Residue Gly1326 of the N-type Calcium Channel α 1B Subunit Controls Reversibility of ω-Conotoxin GVIA and MVIIA Block

Journal of Biological Chemistry

Volumn 276, Issue 19, 2001, Pages 15728-15735

  Feng, Zhong Ping ^a,b   Hamid, Jawed ^a   Doering, Clinton ^a,b   Bosey, Gregory M ^c   Snutch, Terrance P ^c   Zamponi, Gerald W ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b NeuroMed Technologies Inc   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BARIUM; CALCIUM;

MUTANT CHANNEL ACTIVITY;

BIOCHEMISTRY;

AMINO ACID; ARGININE; BARIUM; CALCIUM; CALCIUM CHANNEL N TYPE; GLUTAMIC ACID; GLYCINE; OMEGA CONOTOXIN GVIA; OMEGA CONOTOXIN MVIIA; PROLINE; CALCIUM CHANNEL BLOCKING AGENT; OMEGA CONOTOXIN; PROTEIN SUBUNIT;

ALPHA CHAIN; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; MOLECULAR INTERACTION; MUTATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; BINDING SITE; CELL LINE; CELL MEMBRANE POTENTIAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; GENETIC TRANSFECTION; KINETICS; METABOLISM; MOLECULAR GENETICS; PATCH CLAMP; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARGININE; BINDING SITES; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, N-TYPE; CELL LINE; GLUTAMIC ACID; GLYCINE; HUMANS; KINETICS; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OMEGA-CONOTOXIN GVIA; OMEGA-CONOTOXINS; PATCH-CLAMP TECHNIQUES; PROLINE; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; TRANSFECTION;

EID: 0035844171     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100406200     Document Type: Article

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