Intrathecal α-conotoxins Vc1.1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic pain

Neuropharmacology

Volumn 62, Issue 7, 2012, Pages 2202-2207

  Napier, I A ^a   Klimis, H ^a   Rycroft, B K ^a   Jin, A H ^b   Alewood, P F ^b   Motin, L ^b   Adams, D J ^b,c   Christie, M J ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c RMIT UNIVERSITY   (Australia)

Author keywords

Allodynia; Conotoxin; Intrathecal; nAChR; Nicotinic; Pain

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID B; ALPHA CONOTOXIN AUIB; ALPHA CONOTOXIN MII; ALPHA CONOTOXIN VC1.1; ANALGESIC AGENT; BACLOFEN; BUNGAROTOXIN RECEPTOR; CHOLINERGIC RECEPTOR; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA3; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG TARGETING; FEMALE; IN VITRO STUDY; MALE; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROPATHIC PAIN; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SENSORY NERVE; SYNAPTIC TRANSMISSION;

EID: 84859111177     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.01.016     Document Type: Article

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