Identification of the single channels that underlie the N-type and L- type calcium currents in bullfrog sympathetic neurons

Journal of Neuroscience

Volumn 17, Issue 8, 1997, Pages 2658-2668

  Elmslie, Keith S ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BayK 8644; cell attached patch clamp; L type calcium channels; N type calcium channels; sympathetic neurons; conotoxin GVIA

Indexed keywords

CALCIUM CHANNEL;

ANIMAL CELL; ARTICLE; BULLFROG; CALCIUM CONDUCTANCE; CALCIUM CURRENT; CHANNEL GATING; NERVE POTENTIAL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; REPOLARIZATION; SYMPATHETIC NERVE;

EID: 0030909865     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-08-02658.1997     Document Type: Article

References (15)

1. Aosaki T, Kasai H (1989) Characterization of two kinds of high-voltage-activated Ca-channel currents in chick sensory neurons. Differential sensitivity to dihydropyridines and ω-conotoxin GVIA. Pflügers Arch 414:150-156.
2. Boland LM, Morrill JA, Bean BP (1994) ω-Conotoxin block of N-type calcium channels in frog and rat sympathetic neurons. J Neurosci 14:5011-5027.
3. 2+ channel kinetics by receptor agonists in IMR32 cells. Biophys J 70:2144-2154.
4. Delcour AH, Tsien RW (1993) Altered prevalence of gating modes in neurotransmitter inhibition of N-type calcium channels. Science 259:980-984.
5. Delcour AH, Lipscombe D, Tsien RW (1993) Multiple modes of N-type calcium channel activity distinguished by differences in gating kinetics. J Neurosci 13:181-194.
6. Elmslie KS (1992) Calcium current modulation in frog sympathetic neurones: multiple neurotransmitters and G proteins. J Physiol (Lond) 451:229-246.
7. Elmslie KS, Kammermeier PJ, Jones SW (1992) Calcium current modulation in frog sympathetic neurones: L-current is relatively insensitive to neurotransmitters. J Physiol (Lond) 456:107-123.
8. 2+ channel types and their modulation in bullfrog sympathetic neurons. Neuron 13:217-228.
9. Forti L, Pietrobon D (1993) Functional diversity of L-type calcium channels in rat cerebellar neurons. Neuron 10:437-450.
10. Fox AP, Nowycky MC, Tsien RW (1987) Single-channel recordings of three types of calcium channels in chick sensory neurones. J Physiol (Lond) 394:173-200.
11. Fujita Y, Mynlieff M, Dirksen RT, Kim M-S, Niidome T, Nakai J, Friedrich T, Iwabe N, Miyata T, Furuichi T, Furutama D, Mikoshiba K, Mori Y, Beam KG (1993) Primary structure and functional expression of the ω-conotoxin-sensitive N-typc calcium channel from rabbit brain. Neuron 10:585-598.
12. 2+ channels in evoked release of norepinephrine from sympathetic neurons. Science 239:57-61.
13. Horn R, Marty A (1988) Muscarinic activation of ionic currents measured by a new whole-cell recording method. J Gen Physiol 92:145-159.
14. Jones SW (1987) Sodium currents in dissociated bullfrog sympathetic neurones. J Physiol (Lond) 389:605-627.
15. Jones SW, Jacobs LS (1990) Dihydropyridine actions on calcium currents of frog sympathetic neurons. J Neurosci 10:2261-2267.