The novel anticonvulsant drug, gabapentin (neurontin), binds to the α2δ subunit of a calcium channel

Journal of Biological Chemistry

Volumn 271, Issue 10, 1996, Pages 5768-5776

  Gee, Nicolas S ^a   Brown, Jason P ^a   Dissanayake, Visaka U K ^a   Offord, James ^b   Thurlow, Richard ^c   Woodruff, Geoffrey N ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PFIZER INC   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CALCIUM CHANNEL; CALCIUM ION; COMPLEMENTARY DNA; GABAPENTIN; PROTEIN SUBUNIT;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DRUG MECHANISM; EPILEPSY; MONKEY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN GLYCOSYLATION; PROTEIN ISOLATION; PROTEIN PURIFICATION; SWINE;

ACETIC ACIDS; AMINES; ANIMALS; ANTICONVULSANTS; CALCIUM CHANNELS; CELL LINE; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; CEREBRAL CORTEX; CHROMATOGRAPHY; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; CYCLOHEXANECARBOXYLIC ACIDS; DNA, COMPLEMENTARY; DURAPATITE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GAMMA-AMINOBUTYRIC ACID; KINETICS; MACROMOLECULAR SUBSTANCES; MOLECULAR WEIGHT; MUSCLE, SKELETAL; RABBITS; RECOMBINANT PROTEINS; SWINE; TRANSFECTION; TRITIUM;

ANIMALIA; ORYCTOLAGUS CUNICULUS; SUS SCROFA;

EID: 0029975930     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.10.5768     Document Type: Article

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