Reduced Paneth cell α-defensins in ileal Crohn's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 50, 2005, Pages 18129-18134

  Wehkamp, Jan ^a   Salzman, Nita H ^b   Porter, Edith ^c,d   Nuding, Sabine ^e,f   Weichenthal, Michael ^g   Petras, Robert E ^h   Shen, Bo ⁱ   Schaeffeler, Elke ^f   Schwab, Matthias ^f   Linzmeier, Rose ^d   Feathers, Ryan W ^a   Chu, Hiutung ^a   Lima Jr , Heriberto ^c   Fellermann, Klaus ^e,f   Ganz, Tomas ^d   Stange, Eduard F ^e,f   Bevins, Charles L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c CALIFORNIA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e ROBERT BOSCH HOSPITAL   (Germany)

^f DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^g UNIVERSITY OF KIEL   (Germany)

^h Northeastern Ohio Medical University   (United States)

ⁱ LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Bacteria; Inflammatory bowel disease; Innate immunity; Intestine

Indexed keywords

ALPHA DEFENSIN; ALPHA DEFENSIN 5; ALPHA DEFENSIN 6; ANTIINFECTIVE AGENT; TISSUE EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; COLON DISEASE; CONTROLLED STUDY; CROHN DISEASE; DISEASE PREDISPOSITION; EXPERIMENTAL MODEL; GENETIC PREDISPOSITION; HISTOPATHOLOGY; HOST RESISTANCE; HUMAN; HUMAN TISSUE; ILEITIS; ILEUM DISEASE; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; INTESTINE FLORA; MOUSE; MUCOSA INFLAMMATION; MUCOSAL IMMUNITY; NONHUMAN; PANETH CELL; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; ULCERATIVE COLITIS;

ALPHA-DEFENSINS; ANALYSIS OF VARIANCE; ANIMALS; CROHN DISEASE; HUMANS; ILEITIS; ILEUM; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; OHIO; PANETH CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ANIMALIA; MUS MUSCULUS;

EID: 29144483937     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0505256102     Document Type: Article

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