-
1
-
-
59149087627
-
Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study
-
Silverberg, M.S. et al. Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. Nat. Genet. 41, 216-220 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 216-220
-
-
Silverberg, M.S.1
-
2
-
-
48349136889
-
Genome-wide association defnes more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett, J.C. et al. Genome-wide association defnes more than 30 distinct susceptibility loci for Crohn's disease. Nat. Genet. 40, 955-962 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
-
3
-
-
44349136821
-
Genetic determinants of ulcerative colitis include the ECM1 locus and fve loci implicated in Crohn's disease
-
Fisher, S.A. et al. Genetic determinants of ulcerative colitis include the ECM1 locus and fve loci implicated in Crohn's disease. Nat. Genet. 40, 710-712 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 710-712
-
-
Fisher, S.A.1
-
4
-
-
44349173654
-
Replication of signals from recent studies of Crohn's disease identifes previously unknown disease loci for ulcerative colitis
-
Franke, A. et al. Replication of signals from recent studies of Crohn's disease identifes previously unknown disease loci for ulcerative colitis. Nat. Genet. 40, 713-715 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 713-715
-
-
Franke, A.1
-
5
-
-
55049111426
-
Sequence variants in IL10 ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
-
Franke, A. et al. Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat. Genet. 40, 1319-1323 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 1319-1323
-
-
Franke, A.1
-
6
-
-
42749096082
-
Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifes two susceptibility loci harboring CARD9 and IL18RAP
-
Zhernakova, A. et al. Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifes two susceptibility loci harboring CARD9 and IL18RAP. Am. J. Hum. Genet. 82, 1202-1210 (2008).
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 1202-1210
-
-
Zhernakova, A.1
-
7
-
-
58149345887
-
Practical aspects of imputation-driven meta-analysis of genome-wide association studies
-
de Bakker, P.I. et al. Practical aspects of imputation-driven meta-analysis of genome-wide association studies. Hum. Mol. Genet. 17, R122-R128 (2008).
-
(2008)
Hum. Mol. Genet.
, vol.17
-
-
De Bakker, P.I.1
-
8
-
-
37249034766
-
Systematic association mapping identifes NELL1 as a novel IBD disease gene
-
Franke, A. et al. Systematic association mapping identifes NELL1 as a novel IBD disease gene. PLoS One 2, e691 (2007).
-
(2007)
PLoS One
, vol.2
-
-
Franke, A.1
-
9
-
-
48349122755
-
Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis
-
Goyette, P. et al. Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis. Mucosal Immunol. 1, 131-138 (2008).
-
(2008)
Mucosal Immunol.
, vol.1
, pp. 131-138
-
-
Goyette, P.1
-
10
-
-
70649103789
-
Genome-wide association study of ulcerative colitis identifes three new susceptibility loci, including the HNF4A region
-
Barrett, J.C. et al. Genome-wide association study of ulcerative colitis identifes three new susceptibility loci, including the HNF4A region. Nat. Genet. 41, 1330-1334 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 1330-1334
-
-
Barrett, J.C.1
-
11
-
-
52949091918
-
Loci on 20q13 and 21q22 are associated with pediatric-onset infammatory bowel disease
-
Kugathasan, S. et al. Loci on 20q13 and 21q22 are associated with pediatric-onset infammatory bowel disease. Nat. Genet. 40, 1211-1215 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 1211-1215
-
-
Kugathasan, S.1
-
12
-
-
70649086082
-
A genome-wide association study identifes three new susceptibility loci for ulcerative colitis in the Japanese population
-
Asano, K. et al. A genome-wide association study identifes three new susceptibility loci for ulcerative colitis in the Japanese population. Nat. Genet. 41, 1325-1329 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 1325-1329
-
-
Asano, K.1
-
13
-
-
70649113728
-
Common variants at fve new loci associated with early-onset infammatory bowel disease
-
Imielinski, M. et al. Common variants at fve new loci associated with early-onset infammatory bowel disease. Nat. Genet. 41, 1335-1340 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 1335-1340
-
-
Imielinski, M.1
-
14
-
-
67650255063
-
Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease
-
McGovern, D.P. et al. Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease. Infamm. Bowel Dis. 15, 883-889 (2009).
-
(2009)
Infamm. Bowel Dis.
, vol.15
, pp. 883-889
-
-
McGovern, D.P.1
-
15
-
-
46249124976
-
Deubiquitylation and regulation of the immune response
-
Sun, S.C. Deubiquitylation and regulation of the immune response. Nat. Rev. Immunol. 8, 501-511 (2008).
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 501-511
-
-
Sun, S.C.1
-
16
-
-
50449111452
-
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
-
Graham, R.R. et al. Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat. Genet. 40, 1059-1061 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 1059-1061
-
-
Graham, R.R.1
-
17
-
-
66049120977
-
Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-κB signalling
-
Trynka, G. et al. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-κB signalling. Gut 58, 1078-1083 (2009).
-
(2009)
Gut
, vol.58
, pp. 1078-1083
-
-
Trynka, G.1
-
18
-
-
66349090778
-
Phospholipase A2 structure/function mechanism, and signaling
-
Burke, J.E. & Dennis, E.A. Phospholipase A2 structure/function, mechanism, and signaling. J. Lipid Res. 50 Suppl, S237-S242 (2009).
-
(2009)
J. Lipid Res.
, vol.50
, Issue.SUPPL.
-
-
Burke, J.E.1
Dennis, E.A.2
-
19
-
-
67149095289
-
Primary biliary cirrhosis associated with HLA IL12A, and IL12RB2 variants
-
Hirschfeld, G.M. et al. Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. N. Engl. J. Med. 360, 2544-2555 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 2544-2555
-
-
Hirschfeld, G.M.1
-
20
-
-
69449101386
-
Allele-specifc chromatin remodeling in the ZPBP2/GSDMB/ ORMDL3 locus associated with the risk of asthma and autoimmune disease
-
Verlaan, D.J. et al. Allele-specifc chromatin remodeling in the ZPBP2/GSDMB/ ORMDL3 locus associated with the risk of asthma and autoimmune disease. Am. J. Hum. Genet. 85, 377-393 (2009).
-
(2009)
Am. J. Hum. Genet.
, vol.85
, pp. 377-393
-
-
Verlaan, D.J.1
-
21
-
-
34547216747
-
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
-
Moffatt, M.F. et al. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448, 470-473 (2007).
-
(2007)
Nature
, vol.448
, pp. 470-473
-
-
Moffatt, M.F.1
-
22
-
-
68949214606
-
Biphasic, bidirectional regulation of NF-κB by endoplasmic reticulum stress
-
Kitamura, M. Biphasic, bidirectional regulation of NF-κB by endoplasmic reticulum stress. Antioxid. Redox Signal. 11, 2353-2364 (2009).
-
(2009)
Antioxid. Redox Signal.
, vol.11
, pp. 2353-2364
-
-
Kitamura, M.1
-
23
-
-
50249116184
-
The endoplasmic reticulum stress response in immunity and autoimmunity
-
Todd, D.J., Lee, A.H. & Glimcher, L.H. The endoplasmic reticulum stress response in immunity and autoimmunity. Nat. Rev. Immunol. 8, 663-674 (2008).
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 663-674
-
-
Todd, D.J.1
Lee, A.H.2
Glimcher, L.H.3
-
24
-
-
0036046814
-
ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins
-
RESEARCH0027
-
Hjelmqvist, L. et al. ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins. Genome Biol. 3, RESEARCH0027 (2002).
-
(2002)
Genome Biol.
, vol.3
-
-
Hjelmqvist, L.1
-
25
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007).
-
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 559-575
-
-
Purcell, S.1
-
26
-
-
34548849168
-
TRAF1-C5 is a risk locus for rheumatiod arthritis: A genomewide study
-
Plenge, R.M. et al. TRAF1-C5 is a risk locus for rheumatiod arthritis: a genomewide study. N. Engl. J. Med. 357, 1199-1209 (2007).
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 1199-1209
-
-
Plenge, R.M.1
-
27
-
-
0034282912
-
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response
-
Wang, Y. et al. Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. J. Biol. Chem. 275, 27013-27020 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27013-27020
-
-
Wang, Y.1
|