Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

Gut

Volumn 60, Issue 9, 2011, Pages 1229-1235

  Plantinga, Theo S ^a   Crisan, Tania O ^a   Oosting, Marije ^a   Van De Veerdonk, Frank L ^a   De Jong, Dirk J ^a   Philpott, Dana J ^b   Van Der Meer, Jos W M ^a   Girardin, Stephen E ^b   Joosten, Leo A B ^a   Netea, Mihai G ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; AUTOPHAGY RELATED 16 LIKE 1 PROTEIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ARTICLE; ATG16L1 GENE; AUTOPHAGY; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE PRODUCTION; GENE; GENE EXPRESSION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ADENINE; AUTOPHAGY; CARRIER PROTEINS; CASPASE 1; CELLS, CULTURED; CROHN DISEASE; CYTOKINES; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; NOD2 SIGNALING ADAPTOR PROTEIN; POLYMORPHISM, GENETIC; RNA, MESSENGER;

EID: 80051550866     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gut.2010.228908     Document Type: Article

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