The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

European Journal of Immunology

Volumn 33, Issue 11, 2003, Pages 2987-2997

  Heil, Florian ^a   Ahmad Nejad, Parviz ^b   Hemmi, Hiroaki ^c   Hochrein, Hubertus ^a   Ampenberger, Franziska ^a   Gellert, Tanja ^a   Dietrich, Harald ^a   Lipford, Grayson ^d   Takeda, Kiyoshi ^c   Akira, Shizuo ^c   Wagner, Hermann ^a   Bauer, Stefan ^a  

^a Inst Med Microbiol Immunol Hyg   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c OSAKA UNIVERSITY   (Japan)

^d PFIZER INC   (United States)

Author keywords

Cellular activation; Endosomal maturation; Molecular biology; Toll like receptor

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; BAFILOMYCIN A1; CYTOKINE; GANCICLOVIR; GUANOSINE DERIVATIVE; HYBRID PROTEIN; IMIDAZOQUINOLINE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LOXORIBINE; MITOGEN ACTIVATED PROTEIN KINASE; RESIQUIMOD; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 9; TUMOR VACCINE;

ACIDIFICATION; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL ACTIVATION; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; CPG ISLAND; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG MECHANISM; DRUG STRUCTURE; ENDOSOME; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; LYSOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; CYTOPLASMIC VESICLES; DNA-BINDING PROTEINS; GUANOSINE; HUMANS; IMIDAZOLES; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MITOGENS; MULTIGENE FAMILY; MYELOID DIFFERENTIATION FACTOR 88; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; SPLEEN; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS;

EID: 0242391997     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200324238     Document Type: Article

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