DNA binding to proteolytically activated TLR9 is sequence-independent and enhanced by DNA curvature

EMBO Journal

Volumn 31, Issue 4, 2012, Pages 919-931

  Li, Yue ^a   Berke, Ian C ^a   Modis, Yorgo ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

CpG; DNA curvature; innate immune receptor; nucleic acid recognition; Toll like receptor 9

Indexed keywords

CURVED DNA; HIGH MOBILITY GROUP B1 PROTEIN; HISTONE H2A; HISTONE H2B; PHOSPHODIESTERASE; PHOSPHOROTHIOIC ACID; TOLL LIKE RECEPTOR 9;

ANIMAL CELL; ARTICLE; AUTOIMMUNE DISEASE; DISEASE ASSOCIATION; DNA BINDING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN NUCLEIC ACID INTERACTION; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; BASE SEQUENCE; DNA; DNA PRIMERS; MICE; NF-KAPPA B; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEOLYSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 9;

EID: 84863129261     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.441     Document Type: Article

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