What is behind the non-antibiotic properties of minocycline?

Pharmacological Research

Volumn 67, Issue 1, 2013, Pages 18-30

  Garrido Mesa, N ^a   Zarzuelo, A ^a   Galvez J ^a  

^a UNIVERSITY OF GRANADA   (Spain)

Author keywords

Anti apoptotic; Anti inflammatory; Antibiotic; Immunomodulatory; Minocycline; Tetracycline

Indexed keywords

CASPASE; CLOZAPINE; CYCLOOXYGENASE 2; FLUVOXAMINE; INDUCIBLE NITRIC OXIDE SYNTHASE; MATRIX METALLOPROTEINASE; MINOCYCLINE; NEUROLEPTIC AGENT; PAROXETINE; PLACEBO; SECRETORY PHOSPHOLIPASE A2; SERTRALINE; TETRACYCLINE;

ADAPTIVE IMMUNITY; ADD ON THERAPY; ADJUVANT THERAPY; ALZHEIMER DISEASE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ASTHMA; BRAIN ISCHEMIA; CELL PROLIFERATION; CONTROLLED CLINICAL TRIAL (TOPIC); DEGENERATIVE DISEASE; DEPRESSIVE PSYCHOSIS; DRUG DEPENDENCE; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; DRUG STRUCTURE; DRUG TOLERABILITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME SPECIFICITY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMORAL IMMUNITY; IC 50; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; INNATE IMMUNITY; MACROPHAGE; MAJOR DEPRESSION; MICROGLIA; MONOCYTE; MULTIPLE SCLEROSIS; NERVE FUNCTION; NERVOUS SYSTEM INFLAMMATION; NEUROPATHIC PAIN; NEUROPROTECTION; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REVIEW; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIOXIDANTS; APOPTOSIS; CELL PROLIFERATION; ENZYME INHIBITORS; HUMANS; IMMUNOLOGIC FACTORS; MINOCYCLINE; NEURONS;

EID: 84870927178     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2012.10.006     Document Type: Review

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