-
1
-
-
34347397335
-
5-Lipoxygenase: Regulation of expression and enzyme activity
-
Rådmark O, Werz O, Steinhilber D, Samuelsson B., 5-Lipoxygenase: regulation of expression and enzyme activity. Trends Biochem Sci 2007; 32: 332-341.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 332-341
-
-
Rådmark, O.1
Werz, O.2
Steinhilber, D.3
Samuelsson, B.4
-
2
-
-
0142093151
-
5-lipoxygenase and atherosclerosis
-
Mehrabian M, Allayee H., 5-lipoxygenase and atherosclerosis. Curr Opin Lipidol 2003; 14: 447-457.
-
(2003)
Curr Opin Lipidol
, vol.14
, pp. 447-457
-
-
Mehrabian, M.1
Allayee, H.2
-
3
-
-
2642693710
-
Age-associated up-regulation of neuronal 5-lipoxygenase expression: Putative role in neuronal vulnerability
-
Uz T, Pesold C, Longone P, Manev H., Age-associated up-regulation of neuronal 5-lipoxygenase expression: putative role in neuronal vulnerability. FASEB J 1998; 12: 439-449.
-
(1998)
FASEB J
, vol.12
, pp. 439-449
-
-
Uz, T.1
Pesold, C.2
Longone, P.3
Manev, H.4
-
4
-
-
34447565153
-
The 5-lipoxygenase enzymatic pathway in the mouse brain: Young versus old
-
Chinnici CM, Yao Y, Praticò D., The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old. Neurobiol Aging 2007; 28: 1457-1462.
-
(2007)
Neurobiol Aging
, vol.28
, pp. 1457-1462
-
-
Chinnici, C.M.1
Yao, Y.2
Praticò, D.3
-
5
-
-
56349145099
-
Oxidative stress hypothesis in Alzheimer's disease: A reappraisal
-
Praticò D., Oxidative stress hypothesis in Alzheimer's disease: a reappraisal. Trends Pharmacol Sci 2008; 29: 609-615.
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 609-615
-
-
Praticò, D.1
-
6
-
-
42049114647
-
5-Lipoxygenase gene disruption reduces amyloid-β pathology in a mouse model of Alzheimer's disease
-
Firuzi O, Zhuo J, Chinnici CM, et al. 5-Lipoxygenase gene disruption reduces amyloid-β pathology in a mouse model of Alzheimer's disease. FASEB J 2008; 22: 1169-1178.
-
(2008)
FASEB J
, vol.22
, pp. 1169-1178
-
-
Firuzi, O.1
Zhuo, J.2
Chinnici, C.M.3
-
7
-
-
34548638560
-
A role for 12/15 lipoxygenase in the amyloid β precursor protein metabolism
-
Succol F, Praticò D., A role for 12/15 lipoxygenase in the amyloid β precursor protein metabolism. J Neurochem 2007; 103: 380-387.
-
(2007)
J Neurochem
, vol.103
, pp. 380-387
-
-
Succol, F.1
Praticò, D.2
-
8
-
-
9644275598
-
Modulation of nuclear factor-B activity by indomethacin influences Aβ levels but not Aβ precursor protein metabolism in a model of Alzheimer's disease
-
Sung S, Yang H, Uryu K, et al. Modulation of nuclear factor-B activity by indomethacin influences Aβ levels but not Aβ precursor protein metabolism in a model of Alzheimer's disease. Am J Pathol 2004; 165: 2197-2206.
-
(2004)
Am J Pathol
, vol.165
, pp. 2197-2206
-
-
Sung, S.1
Yang, H.2
Uryu, K.3
-
9
-
-
44649118752
-
Thromboxane receptor activation mediates isoprostane-induced increases in amyloid pathology in Tg2576 mice
-
Shineman DW, Zhang B, Leight SN, et al. Thromboxane receptor activation mediates isoprostane-induced increases in amyloid pathology in Tg2576 mice. J Neurosci 2008; 28: 4785-4794.
-
(2008)
J Neurosci
, vol.28
, pp. 4785-4794
-
-
Shineman, D.W.1
Zhang, B.2
Leight, S.N.3
-
10
-
-
0036653703
-
Recent advances in the development of γ-secretase inhibitors
-
Josien H., Recent advances in the development of γ-secretase inhibitors. Curr Opin Drug Discov Devel 2002; 5: 513-525.
-
(2002)
Curr Opin Drug Discov Devel
, vol.5
, pp. 513-525
-
-
Josien, H.1
-
11
-
-
0142059785
-
Gleevec inhibits β-amyloid production but not Notch cleavage
-
Netzer WJ, Dou F, Cai D, et al. Gleevec inhibits β-amyloid production but not Notch cleavage. Proc Natl Acad Sci U S A 2003; 100: 12444-12449.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12444-12449
-
-
Netzer, W.J.1
Dou, F.2
Cai, D.3
-
13
-
-
70349492366
-
HPLC quantification of 5-hydroxyeicosatetraenoic acid in human lung cancer tissues
-
Paige M, Saprito MS, Bunyan DA, Shim YM., HPLC quantification of 5-hydroxyeicosatetraenoic acid in human lung cancer tissues. Biomed Chromatogr 2009; 23: 817-821.
-
(2009)
Biomed Chromatogr
, vol.23
, pp. 817-821
-
-
Paige, M.1
Saprito, M.S.2
Bunyan, D.A.3
Shim, Y.M.4
-
14
-
-
1942501585
-
12/15-lipoxygenase is increased in Alzheimer's disease: Possible involvement in brain oxidative stress
-
Praticò D, Zhukareva V, Yao Y, et al. 12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress. Am J Pathol 2004; 164: 1655-1662.
-
(2004)
Am J Pathol
, vol.164
, pp. 1655-1662
-
-
Praticò, D.1
Zhukareva, V.2
Yao, Y.3
-
15
-
-
17444425699
-
Advances in therapy with anti-leukotriene drugs
-
Riccioni G, DiIlio C, Conti P, et al. Advances in therapy with anti-leukotriene drugs. Ann Clin Lab Sci 2004; 34: 379-387.
-
(2004)
Ann Clin Lab Sci
, vol.34
, pp. 379-387
-
-
Riccioni, G.1
Diilio, C.2
Conti, P.3
-
16
-
-
0036023971
-
A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish
-
Geling A, Steiner H, Willem M, et al. A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish. EMBO Rep 2002; 3: 688-694.
-
(2002)
EMBO Rep
, vol.3
, pp. 688-694
-
-
Geling, A.1
Steiner, H.2
Willem, M.3
-
17
-
-
33645523237
-
Involvement of cAMP response element binding protein-1 in arachidonic-induced vascular smooth muscle cell motility
-
Dronadula N, Rizvi F, Blaskova E, et al. Involvement of cAMP response element binding protein-1 in arachidonic-induced vascular smooth muscle cell motility. J Lipid Res 2006; 47: 767-777.
-
(2006)
J Lipid Res
, vol.47
, pp. 767-777
-
-
Dronadula, N.1
Rizvi, F.2
Blaskova, E.3
-
18
-
-
38149123363
-
Regulating gene transcription in response to cyclic AMP elevation
-
Sands WA, Palmer TM., Regulating gene transcription in response to cyclic AMP elevation. Cell Signaling 2008; 20: 460-466.
-
(2008)
Cell Signaling
, vol.20
, pp. 460-466
-
-
Sands, W.A.1
Palmer, T.M.2
-
19
-
-
56449106689
-
Increased 5-lipooxygenase immunoreactivity in hippocampus of patients with Alzheimer's diseases
-
Ikonomovic MD, Abrahamson EE, Uz T, et al. Increased 5-lipooxygenase immunoreactivity in hippocampus of patients with Alzheimer's diseases. J Histochem Cytochem 2008; 56: 1065-1073.
-
(2008)
J Histochem Cytochem
, vol.56
, pp. 1065-1073
-
-
Ikonomovic, M.D.1
Abrahamson, E.E.2
Uz, T.3
-
20
-
-
0034991806
-
5-Lipoxygenase (5-LOX) promoter polymorphism in patients with early-onset and late-onset Alzheimer's disease
-
Qu T, Manev R, Manev H., 5-Lipoxygenase (5-LOX) promoter polymorphism in patients with early-onset and late-onset Alzheimer's disease. J Neuropsychiatry Clin Neurosci 2001; 13: 304-305.
-
(2001)
J Neuropsychiatry Clin Neurosci
, vol.13
, pp. 304-305
-
-
Qu, T.1
Manev, R.2
Manev, H.3
-
21
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J, Selkoe DJ., The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002; 297: 353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
22
-
-
46749097518
-
Inhibition and modulation of gamma-secretase for Alzheimer's disease
-
Wolfe MS., Inhibition and modulation of gamma-secretase for Alzheimer's disease. Neurotherapeutics 2008; 5: 391-398.
-
(2008)
Neurotherapeutics
, vol.5
, pp. 391-398
-
-
Wolfe, M.S.1
-
23
-
-
0037424275
-
PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1
-
Luo WJ, Wang H, Li H, et al. PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1. J Biol Chem 2003; 278: 7850-7854.
-
(2003)
J Biol Chem
, vol.278
, pp. 7850-7854
-
-
Luo, W.J.1
Wang, H.2
Li, H.3
-
24
-
-
32044466055
-
Transcriptional regulation of Pen-2, a key component of the γ-secretase complex, by CREB
-
Wang R, Zhang YW, Sun P, et al. Transcriptional regulation of Pen-2, a key component of the γ-secretase complex, by CREB. Mol Cell Biol 2006; 26: 1347-1354.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 1347-1354
-
-
Wang, R.1
Zhang, Y.W.2
Sun, P.3
-
25
-
-
9644281700
-
Alternative initiation of transcription of the human presenilin 1 gene in SH-SY5Y and SK-N-SH cells. The role of Ets factors in the regulation of presenilin 1
-
Pastorcic M, Das HK., Alternative initiation of transcription of the human presenilin 1 gene in SH-SY5Y and SK-N-SH cells. The role of Ets factors in the regulation of presenilin 1. Eur J Biochem 2004; 271: 4485-4494.
-
(2004)
Eur J Biochem
, vol.271
, pp. 4485-4494
-
-
Pastorcic, M.1
Das, H.K.2
-
26
-
-
40249114794
-
Transcriptional regulation of β-secretase by p25/cdk5 leads to enhanced amyloidogenic processing
-
Wen Y, Yu WH, Maloney B, et al. Transcriptional regulation of β-secretase by p25/cdk5 leads to enhanced amyloidogenic processing. Neuron 2008; 57: 680-690.
-
(2008)
Neuron
, vol.57
, pp. 680-690
-
-
Wen, Y.1
Yu, W.H.2
Maloney, B.3
-
27
-
-
0347356360
-
Transcriptional regulation of BACE-1, the β-amyloid precursor protein β secretase, by Sp1
-
Christensen MA, Zhou W, Qing H, et al. Transcriptional regulation of BACE-1, the β-amyloid precursor protein β secretase, by Sp1. Mol Cell Biol 2004; 24: 865-874.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 865-874
-
-
Christensen, M.A.1
Zhou, W.2
Qing, H.3
-
28
-
-
0033535504
-
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
-
De Strooper B, Annaert W, Cupers P, et al. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature 1999; 398: 518-522.
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
-
29
-
-
18344380083
-
A presenilin-1/γ-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions
-
Marambaud P, Shioi J, Serban G, et al. A presenilin-1/γ-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. EMBO J 2002; 21: 1948-1956.
-
(2002)
EMBO J
, vol.21
, pp. 1948-1956
-
-
Marambaud, P.1
Shioi, J.2
Serban, G.3
-
30
-
-
9144219644
-
Cyclooxygenase (COX)-2 and COX-1 potentiate beta-amyloid peptide generation through mechanisms that involve gamma-secretase activity
-
Qin W, Ho L, Pompl PN, et al. Cyclooxygenase (COX)-2 and COX-1 potentiate beta-amyloid peptide generation through mechanisms that involve gamma-secretase activity. J Biol Chem 2003; 278: 50970-50977.
-
(2003)
J Biol Chem
, vol.278
, pp. 50970-50977
-
-
Qin, W.1
Ho, L.2
Pompl, P.N.3
|