메뉴 건너뛰기




Volumn 70, Issue 3, 2011, Pages 305-312

Post-injury administration of minocycline: An effective treatment for nerve-injury induced neuropathic pain

Author keywords

Analgesia; Analgesics; Glia; Microglia; Pain; Spinal cord

Indexed keywords

MINOCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE P38;

EID: 79957600105     PISSN: 01680102     EISSN: 18728111     Source Type: Journal    
DOI: 10.1016/j.neures.2011.03.012     Document Type: Article
Times cited : (72)

References (35)
  • 4
    • 36749098953 scopus 로고    scopus 로고
    • A novel role of minocycline: attenuating morphine antinociceptive tolerance by inhibition of p38 MAPK in the activated spinal microglia
    • Cui Y., Liao X.X., Liu W., Guo R.X., Wu Z.Z., Zhao C.M., Chen P.X., Feng J.Q. A novel role of minocycline: attenuating morphine antinociceptive tolerance by inhibition of p38 MAPK in the activated spinal microglia. Brain Behav. Immun. 2008, 22(1):114-123.
    • (2008) Brain Behav. Immun. , vol.22 , Issue.1 , pp. 114-123
    • Cui, Y.1    Liao, X.X.2    Liu, W.3    Guo, R.X.4    Wu, Z.Z.5    Zhao, C.M.6    Chen, P.X.7    Feng, J.Q.8
  • 6
    • 33646439133 scopus 로고    scopus 로고
    • Activated microglia contribute to the maintenance of chronic pain after spinal cord injury
    • Hains B.C., Waxman S.G. Activated microglia contribute to the maintenance of chronic pain after spinal cord injury. J. Neurosci. 2006, 26(16):4308-4317.
    • (2006) J. Neurosci. , vol.26 , Issue.16 , pp. 4308-4317
    • Hains, B.C.1    Waxman, S.G.2
  • 7
    • 28744435045 scopus 로고    scopus 로고
    • Intrathecal minocycline attenuates peripheral inflammation-induced hyperalgesia by inhibiting p38 MAPK in spinal microglia
    • Hua X.Y., Svensson C.I., Matsui T., Fitzsimmons B., Yaksh T.L., Webb M. Intrathecal minocycline attenuates peripheral inflammation-induced hyperalgesia by inhibiting p38 MAPK in spinal microglia. Eur. J. Neurosci. 2005, 22(10):2431-2440.
    • (2005) Eur. J. Neurosci. , vol.22 , Issue.10 , pp. 2431-2440
    • Hua, X.Y.1    Svensson, C.I.2    Matsui, T.3    Fitzsimmons, B.4    Yaksh, T.L.5    Webb, M.6
  • 8
    • 0037705314 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain
    • Jin S.X., Zhuang Z.Y., Woolf C.J., Ji R.R. p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. J. Neurosci. 2003, 23(10):4017-4022.
    • (2003) J. Neurosci. , vol.23 , Issue.10 , pp. 4017-4022
    • Jin, S.X.1    Zhuang, Z.Y.2    Woolf, C.J.3    Ji, R.R.4
  • 9
    • 0026727999 scopus 로고
    • An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat
    • Kim S.H., Chung J.M. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 1992, 50(3):355-363.
    • (1992) Pain , vol.50 , Issue.3 , pp. 355-363
    • Kim, S.H.1    Chung, J.M.2
  • 10
    • 17044417657 scopus 로고    scopus 로고
    • Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation
    • Ledeboer A., Sloane E.M., Milligan E.D., Frank M.G., Mahony J.H., Maier S.F., Watkins L.R. Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation. Pain 2005, 115(1-2):71-83.
    • (2005) Pain , vol.115 , Issue.1-2 , pp. 71-83
    • Ledeboer, A.1    Sloane, E.M.2    Milligan, E.D.3    Frank, M.G.4    Mahony, J.H.5    Maier, S.F.6    Watkins, L.R.7
  • 13
    • 65949086600 scopus 로고    scopus 로고
    • Inhibiting astrocytic activation: a novel analgesic mechanism of ketamine at the spinal level?
    • Mei X., Wang W., Wang W., Li Y., Zhang H., Wu S., Li Y., Xu L. Inhibiting astrocytic activation: a novel analgesic mechanism of ketamine at the spinal level?. J. Neurochem. 2009, 109(6):1691-1700.
    • (2009) J. Neurochem. , vol.109 , Issue.6 , pp. 1691-1700
    • Mei, X.1    Wang, W.2    Wang, W.3    Li, Y.4    Zhang, H.5    Wu, S.6    Li, Y.7    Xu, L.8
  • 14
    • 33847417406 scopus 로고    scopus 로고
    • Minocycline and pentoxifylline attenuate allodynia and hyperalgesia and potentiate the effects of morphine in rat and mouse models of neuropathic pain
    • Mika J., Osikowicz M., Makuch W., Przewlocka B. Minocycline and pentoxifylline attenuate allodynia and hyperalgesia and potentiate the effects of morphine in rat and mouse models of neuropathic pain. Eur. J. Pharmacol. 2007, 560(2-3):142-149.
    • (2007) Eur. J. Pharmacol. , vol.560 , Issue.2-3 , pp. 142-149
    • Mika, J.1    Osikowicz, M.2    Makuch, W.3    Przewlocka, B.4
  • 16
    • 73649211066 scopus 로고    scopus 로고
    • Minocycline reduces the injury-induced expression of prodynorphin and pronociceptin in the dorsal root ganglion in a rat model of neuropathic pain
    • Mika J., Rojewska E., Makuch W., Przewlocka B. Minocycline reduces the injury-induced expression of prodynorphin and pronociceptin in the dorsal root ganglion in a rat model of neuropathic pain. Neuroscience 2010, 165(4):1420-1428.
    • (2010) Neuroscience , vol.165 , Issue.4 , pp. 1420-1428
    • Mika, J.1    Rojewska, E.2    Makuch, W.3    Przewlocka, B.4
  • 18
    • 57749200564 scopus 로고    scopus 로고
    • Pathological and protective roles of glia in chronic pain
    • Milligan E.D., Watkins L.R. Pathological and protective roles of glia in chronic pain. Nat. Rev. Neurosci. 2009, 10(1):23-36.
    • (2009) Nat. Rev. Neurosci. , vol.10 , Issue.1 , pp. 23-36
    • Milligan, E.D.1    Watkins, L.R.2
  • 19
    • 0036264576 scopus 로고    scopus 로고
    • Potentiation by ketamine of fentanyl antinociception. I. An experimental study in rats showing that ketamine administered by non-spinal routes targets spinal cord antinociceptive systems
    • Nadeson R., Tucker A., Bajunaki E., Goodchild C.S. Potentiation by ketamine of fentanyl antinociception. I. An experimental study in rats showing that ketamine administered by non-spinal routes targets spinal cord antinociceptive systems. Br. J. Anaesth. 2002, 88(5):685-691.
    • (2002) Br. J. Anaesth. , vol.88 , Issue.5 , pp. 685-691
    • Nadeson, R.1    Tucker, A.2    Bajunaki, E.3    Goodchild, C.S.4
  • 20
    • 34250217010 scopus 로고    scopus 로고
    • Intrathecal administration of ATP produces long-lasting allodynia in rats: differential mechanisms in the phase of the induction and maintenance
    • Nakagawa T., Wakamatsu K., Zhang N., Maeda S., Minami M., Satoh M., Kaneko S. Intrathecal administration of ATP produces long-lasting allodynia in rats: differential mechanisms in the phase of the induction and maintenance. Neuroscience 2007, 147(2):445-455.
    • (2007) Neuroscience , vol.147 , Issue.2 , pp. 445-455
    • Nakagawa, T.1    Wakamatsu, K.2    Zhang, N.3    Maeda, S.4    Minami, M.5    Satoh, M.6    Kaneko, S.7
  • 21
    • 33746354314 scopus 로고    scopus 로고
    • Fractalkine and minocycline alter neuronal activity in the spinal cord dorsal horn
    • Owolabi S.A., Saab C.Y. Fractalkine and minocycline alter neuronal activity in the spinal cord dorsal horn. FEBS Lett. 2006, 580(18):4306-4310.
    • (2006) FEBS Lett. , vol.580 , Issue.18 , pp. 4306-4310
    • Owolabi, S.A.1    Saab, C.Y.2
  • 22
    • 56949085589 scopus 로고    scopus 로고
    • Minocycline prevents the development of neuropathic pain, but not acute pain: possible anti-inflammatory and antioxidant mechanisms
    • Padi S.S., Kulkarni S.K. Minocycline prevents the development of neuropathic pain, but not acute pain: possible anti-inflammatory and antioxidant mechanisms. Eur. J. Pharmacol. 2008, 601(1-3):79-87.
    • (2008) Eur. J. Pharmacol. , vol.601 , Issue.1-3 , pp. 79-87
    • Padi, S.S.1    Kulkarni, S.K.2
  • 23
    • 0037622717 scopus 로고    scopus 로고
    • Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy
    • Raghavendra V., Tanga F., DeLeo J.A. Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J. Pharmacol. Exp. Ther. 2003, 306(2):624-630.
    • (2003) J. Pharmacol. Exp. Ther. , vol.306 , Issue.2 , pp. 624-630
    • Raghavendra, V.1    Tanga, F.2    DeLeo, J.A.3
  • 24
    • 53549086936 scopus 로고    scopus 로고
    • Neuron-glia crosstalk gets serious: role in pain hypersensitivity
    • Ren K., Dubner R. Neuron-glia crosstalk gets serious: role in pain hypersensitivity. Curr. Opin. Anaesthesiol. 2008, 21(5):570-579.
    • (2008) Curr. Opin. Anaesthesiol. , vol.21 , Issue.5 , pp. 570-579
    • Ren, K.1    Dubner, R.2
  • 25
    • 35548937457 scopus 로고    scopus 로고
    • The neuropathic pain triad: neurons, immune cells and glia
    • Scholz J., Woolf C.J. The neuropathic pain triad: neurons, immune cells and glia. Nat. Neurosci. 2007, 10(11):1361-1368.
    • (2007) Nat. Neurosci. , vol.10 , Issue.11 , pp. 1361-1368
    • Scholz, J.1    Woolf, C.J.2
  • 26
    • 0035871840 scopus 로고    scopus 로고
    • Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
    • Tikka T., Fiebich B.L., Goldsteins G., Keinanen R., Koistinaho J. Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J. Neurosci. 2001, 21(8):2580-2588.
    • (2001) J. Neurosci. , vol.21 , Issue.8 , pp. 2580-2588
    • Tikka, T.1    Fiebich, B.L.2    Goldsteins, G.3    Keinanen, R.4    Koistinaho, J.5
  • 27
    • 13144276331 scopus 로고    scopus 로고
    • Neuropathic pain and spinal microglia: a big problem from molecules in " small" glia
    • Tsuda M., Inoue K., Salter M.W. Neuropathic pain and spinal microglia: a big problem from molecules in " small" glia. Trends Neurosci. 2005, 28(2):101-107.
    • (2005) Trends Neurosci. , vol.28 , Issue.2 , pp. 101-107
    • Tsuda, M.1    Inoue, K.2    Salter, M.W.3
  • 28
    • 70349171800 scopus 로고    scopus 로고
    • Crosstalk between spinal astrocytes and neurons in nerve injury-induced neuropathic pain
    • Wang W., Wang W., Mei X., Huang J., Wei Y., Wang Y., Wu S., Li Y. Crosstalk between spinal astrocytes and neurons in nerve injury-induced neuropathic pain. PLoS One 2009, 4(9):e6973.
    • (2009) PLoS One , vol.4 , Issue.9
    • Wang, W.1    Wang, W.2    Mei, X.3    Huang, J.4    Wei, Y.5    Wang, Y.6    Wu, S.7    Li, Y.8
  • 29
    • 0030840882 scopus 로고    scopus 로고
    • Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat
    • Watkins L.R., Martin D., Ulrich P., Tracey K.J., Maier S.F. Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat. Pain 1997, 71(3):225-235.
    • (1997) Pain , vol.71 , Issue.3 , pp. 225-235
    • Watkins, L.R.1    Martin, D.2    Ulrich, P.3    Tracey, K.J.4    Maier, S.F.5
  • 30
    • 0034882399 scopus 로고    scopus 로고
    • Spinal cord glia: new players in pain
    • Watkins L.R., Milligan E.D., Maier S.F. Spinal cord glia: new players in pain. Pain 2001, 93(3):201-205.
    • (2001) Pain , vol.93 , Issue.3 , pp. 201-205
    • Watkins, L.R.1    Milligan, E.D.2    Maier, S.F.3
  • 31
    • 0033539522 scopus 로고    scopus 로고
    • A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
    • Yrjanheikki J., Tikka T., Keinanen R., Goldsteins G., Chan P.H., Koistinaho J. A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc. Natl. Acad. Sci. U.S.A. 1999, 96(23):13496-13500.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , Issue.23 , pp. 13496-13500
    • Yrjanheikki, J.1    Tikka, T.2    Keinanen, R.3    Goldsteins, G.4    Chan, P.H.5    Koistinaho, J.6
  • 32
    • 14044252008 scopus 로고    scopus 로고
    • ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model
    • Zhuang Z.Y., Gerner P., Woolf C.J., Ji R.R. ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model. Pain 2005, 114(1-2):149-159.
    • (2005) Pain , vol.114 , Issue.1-2 , pp. 149-159
    • Zhuang, Z.Y.1    Gerner, P.2    Woolf, C.J.3    Ji, R.R.4
  • 33
    • 34249717859 scopus 로고    scopus 로고
    • Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine
    • Zhuang Z.Y., Kawasaki Y., Tan P.H., Wen Y.R., Huang J., Ji R.R. Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain Behav. Immun. 2007, 21(5):642-651.
    • (2007) Brain Behav. Immun. , vol.21 , Issue.5 , pp. 642-651
    • Zhuang, Z.Y.1    Kawasaki, Y.2    Tan, P.H.3    Wen, Y.R.4    Huang, J.5    Ji, R.R.6
  • 34
    • 33645460235 scopus 로고    scopus 로고
    • A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance
    • Zhuang Z.Y., Wen Y.R., Zhang D.R., Borsello T., Bonny C., Strichartz G.R., Decosterd I., Ji R.R. A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance. J. Neurosci. 2006, 26(13):3551-3560.
    • (2006) J. Neurosci. , vol.26 , Issue.13 , pp. 3551-3560
    • Zhuang, Z.Y.1    Wen, Y.R.2    Zhang, D.R.3    Borsello, T.4    Bonny, C.5    Strichartz, G.R.6    Decosterd, I.7    Ji, R.R.8
  • 35
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983, 16(2):109-110.
    • (1983) Pain , vol.16 , Issue.2 , pp. 109-110
    • Zimmermann, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.