Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 18, 2003, Pages 10483-10487

  Wang, Xin ^a   Zhu, Shan ^a   Drozda, Martin ^a   Zhang, Wenhua ^a   Stavrovskaya, Irina G ^e   Cattaneo, Elena ^b   Ferrante, Robert J ^c,d   Kristal, Bruce S ^e,f   Friedlander, Robert M ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF MILAN   (Italy)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e BURKE MEDICAL RESEARCH INSTITUTE   (United States)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE; CELL PROTEIN; CYTOCHROME C; MINOCYCLINE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE COURSE; DISEASE MODEL; DRUG EFFECT; DRUG EFFICACY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; MOUSE; NERVE CELL; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; CASPASES; CELL DEATH; CELL LINE; DISEASE MODELS, ANIMAL; HUMANS; HUNTINGTON DISEASE; MICE; MINOCYCLINE; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0041335559     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1832501100     Document Type: Article

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