Proteomic analysis of the anti-inflammatory action of minocycline

Proteomics

Volumn 11, Issue 1, 2011, Pages 42-51

  Dunston, Christopher R ^a   Griffiths, Helen R ^a   Lambert, Peter A ^a   Staddon, Susan ^b   Vernallis, Ann B ^a  

^a ASTON UNIVERSITY   (United Kingdom)

^b OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

2 DE; Cell biology; Lipopolysaccharide; Macrophage; Minocycline; Tigecycline

Indexed keywords

ALDEHYDE REDUCTASE; DOXYCYCLINE; HEAT SHOCK PROTEIN; LIPOPOLYSACCHARIDE; MINOCYCLINE; NITRIC OXIDE; OXYTETRACYCLINE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; TIGECYCLINE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL METABOLISM; CONTROLLED STUDY; LIQUID CHROMATOGRAPHY; MACROPHAGE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; TWO DIMENSIONAL ELECTROPHORESIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CHROMATOGRAPHY, LIQUID; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; IMMUNOBLOTTING; LIPOPOLYSACCHARIDES; MASS SPECTROMETRY; MICE; MINOCYCLINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROTEOMICS; TETRACYCLINES;

EID: 78650408816     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201000273     Document Type: Article

References (42)

1. Kraus, R. L., Pasieczny, R., Lariosa-Willingham, K., Turner, M. S. et al., Antioxidant properties of minocycline: neuroprotection in an oxidative stress assay and direct radical-scavenging activity. J. Neurochem. 2005, 94, 819-827.
2. Kelly, K. J., Sutton, T. A., Weathered, N., Ray, N. et al., Minocycline inhibits apoptosis and inflammation in a rat model of ischemic renal injury. Am. J. Physiol. Renal Physiol. 2004, 287, F760-F766.
3. Saikali, Z., Singh, G., Doxycycline and other tetracyclines in the treatment of bone metastasis. Anticancer Drugs 2003, 14, 773-778.
4. Yrjanheikki, J., Tikka, T., Keinanen, R., Goldsteins, G. et al., A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc. Natl. Acad. Sci. USA 1999, 96, 13496-13500.
5. Yrjanheikki, J., Keinanen, R., Pellikka, M., Hokfelt, T. et al., Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. Proc. Natl. Acad. Sci. USA 1998, 95, 15769-15774.
6. Amin, A. R., Attur, M. G., Thakker, G. D., Patel, P. D. et al., A novel mechanism of action of tetracyclines: effects on nitric oxide synthases. Proc. Natl. Acad. Sci. USA 1996, 93, 14014-14019.
7. Tilley, B. C., Alarcon, G. S., Heyse, S. P., Trentham, D. E. et al., Minocycline in rheumatoid arthritis. A 48-week, double-blind, placebo-controlled trial. MIRA Trial Group. Ann. Intern. Med. 1995, 122, 81-89.
8. Bogren, A., Teles, R. P., Torresyap, G., Haffajee, A. D. et al., Locally delivered doxycycline during supportive periodontal Therapy: a 3-year study. J. Periodontol. 2008, 79, 827-835.
9. Romero-Perez, D., Fricovsky, E., Yamasaki, K. G., Griffin, M. et al., Cardiac uptake of minocycline and mechanisms for in vivo cardioprotection. J. Am. Coll. Cardiol. 2008, 52, 1086-1094.
10. Du, Y., Ma, Z., Lin, S., Dodel, R. C. et al., Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease. Proc. Natl. Acad. Sci. USA 2001, 98, 14669-14674.
11. Zabad, R. K., Metz, L. M., Todoruk, T. R., Zhang, Y. et al., The clinical response to minocycline in multiple sclerosis is accompanied by beneficial immune changes: a pilot study. Mult. Scler. 2007, 13, 517-526.
12. Gordon, P. H., Moore, D. H., Miller, R. G., Florence, J. M. et al., Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial. Lancet Neurol. 2007, 6, 1045-1053.
13. Zhu, S., Stavrovskaya, I. G., Drozda, M., Kim, B. Y. S. et al., Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature 2002, 417, 74-78.
14. D'Agostino, P., Arcoleo, F., Barbera, C., Di Bella, G. et al., Tetracycline inhibits the nitric oxide synthase activity induced by endotoxin in cultured murine macrophages. Eur. J. Pharmacol. 1998, 346, 283-290.
15. Lai, A. Y., Todd, K. G., Hypoxia-activated microglial mediators of neuronal survival are differentially regulated by tetracyclines. Glia 2006, 53, 809-816.
16. Chen, C., Chen, Y. H., Lin, W. W., Involvement of p38 mitogen-activated protein kinase in lipopolysaccharide-induced iNOS and COX-2 expression in J774 macrophages. Immunology 1999, 97, 124-129.
17. Kirkwood, K., Martin, T., Agnello, K., Kim, Y. J., Differential regulation of MMP-13 by chemical modified tetracyclines in osteoblasts. J. Int. Acad. Periodontol. 2004, 6, 39-46.
18. Alano, C. C., Kauppinen, T. M., Valls, A. V., Swanson, R. A., Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations. Proc. Natl. Acad. Sci. 2006, 103, 9685-9690.
19. Dalm, D., Palm, G. J., Aleksandrov, A., Simonson, T. et al., Nonantibiotic properties of tetracyclines: structural basis for inhibition of secretory phospholipase A2. J. Mol. Biol. 2010, 398, 83-96.
20. Gutsmann, T., Muller, M., Carroll, S. F., MacKenzie, R. C. et al., Dual role of lipopolysaccharide (LPS)-binding protein in neutralization of LPS and enhancement of LPS-induced activation of mononuclear cells. Infect. Immun. 2001, 69, 6942-6950.
21. Kawai, T., Akira, S., TLR signaling. Semin. Immunol. 2007, 19, 24-32.
22. Kawai, T., Akira, S., Signaling to NF-kappaB by toll-like receptors. Trends Mol. Med. 2007, 13, 460-469.
23. Taylor, B. S., Geller, D. A., Molecular regulation of the human inducible nitric oxide synthase (iNOS) gene. Shock 2000, 13, 413-424.
24. Cuzzocrea, S., Role of nitric oxide and reactive oxygen species in arthritis. Curr. Pharm. Des. 2006, 12, 3551-3570.
25. Tsukahara, Y., Morisaki, T., Kojima, M., Uchiyama, A. et al., iNOS expression by activated neutrophils from patients with sepsis. ANZ J. Surg. 2001, 71, 15-20.
26. Mosmann, T., Rapid colorimetric assay for cellular growth and survival:Application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65, 55-63.
27. Bergeron, J., Ammirati, M., Danley, D., James, L. et al., Glycylcyclines bind to the high-affinity tetracycline ribosomal binding site and evade Tet(M)- and Tet(O)-mediated ribosomal protection. Antimicrob. Agents Chemother. 1996, 40, 2226-2228.
28. Walters, J. D., Characterization of minocycline transport by human neutrophils. J. Periodontol. 2006, 77, 1964-1968.
29. Walters, J. D., Nakkula, R. J., Maney, P., Modulation of gingival fibroblast minocycline accumulation by biological mediators. J. Dent. Res. 2005, 84, 320-323.
30. Saibil, H. R., Chaperone machines in action. Curr. Opin. Struct. Biol. 2008, 18, 35-42.
31. Saba, J. A., McComb, M. E., Potts, D. L., Costello, C. E. et al., Proteomic mapping of stimulus-specific signaling pathways involved in THP-1 cells exposed to Porphyromonas gingivalis or its purified components. J. Proteome Res. 2007, 6, 2211-2221.
32. Zheng, L., He, M., Long, M., Blomgran, R. et al., Pathogen-induced apoptotic neutrophils express heat shock proteins and elicit activation of human macrophages. J. Immunol. 2004, 173, 6319-6326.
33. Edelman, D. A., Jiang, Y., Tyburski, J. G., Wilson, R. F. et al., Lipopolysaccharide up-regulates heat shock protein expression in rat lung pericytes. J. Surg. Res. 2007, 140, 171-176.
34. Wang, X., Li, Y., Kuang, J., Zhao, Y. et al., Increased heat shock protein 70 expression in the pancreas of rats with endotoxic shock. World J. Gastroenterol. 2006, 7, 780-783.
35. Rittner, H. L., Hafner, V., Klimiuk, P. A., Szweda, L. I. et al., Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis. J. Clin. Invest. 1999, 103, 1007-1013.
36. Kaiserova, K., Tang, X.-L., Srivastava, S., Bhatnagar, A., Role of nitric oxide in regulating aldose reductase activation in the ischemic heart. J. Biol. Chem. 2008, 283, 9101-9112.
37. Ramana, K. V., Srivastava, S. K., Mediation of aldose reductase in lipopolysaccharide-induced inflammatory signals in mouse peritoneal macrophages. Cytokine 2006, 36, 115-122.
38. Reddy, A. B. M., Srivastava, S. K., Ramana, K. V., Anti-inflammatory effect of aldose reductase inhibition in murine polymicrobial sepsis. Cytokine 2009, 48, 170-176.
39. Nakanishi-Matsui, M., Sekiya, M., Nakamoto, R. K., Futai, M., The mechanism of rotating proton pumping ATPases. Biochimica et Biophysica Acta 2010, 8, 1343-1352.
40. Nakamoto, R. K., Baylis Scanlon, J. A., Al-Shawi, M. K., The rotary mechanism of the ATP synthase. Arch. Biochem. Biophys. 2008, 476, 43-50.
41. Sultana, R., Reed, T., Perluigi, M., Coccia, R. et al., Proteomic identification of nitrated brain proteins in amnestic mild cognitive impairment: a regional study. J. Cell. Mol. Med. 2007, 11, 839-851.
42. Hojlund, K., Wrzesinski, K., Larsen, P. M., Fey, S. J. et al., Proteome analysis reveals phosphorylation of ATP synthase β-subunit in human skeletal muscle and proteins with potential roles in type 2 diabetes. J. Biol. Chem. 2003, 278, 10436-10442.