Minocycline, schizophrenia and GluR1 glutamate receptors

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 33, Issue 1, 2009, Pages 166-

  Manev, Radmila ^a   Manev, Hari ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; GLUTAMATE RECEPTOR 1; MINOCYCLINE;

CENTRAL NERVOUS SYSTEM; COGNITIVE DEFECT; DRUG RECEPTOR BINDING; LETTER; MICROGLIA; NONHUMAN; SCHIZOPHRENIA;

ANIMALS; HUMANS; MICE; MINOCYCLINE; RECEPTORS, AMPA; SCHIZOPHRENIA;

EID: 58149343320     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2008.11.004     Document Type: Letter

References (8)

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2. Coyle J.T. Glutamate and schizophrenia: beyond the dopamine hypothesis. Cell Mol Neurobiol 26 (2006) 365-384
3. Hashimoto K. Microglial activation in schizophrenia and minocycline treatment. Prog Neuro-psychopharmacol Biol Psychiatry 32 (2008) 1758-1759
4. Imbesi M., Uz T., Manev R., Sharma R.P., and Manev H. Minocycline increases phosphorylation and membrane insertion of neuronal GluR1 receptors. Neurosci Lett (2008) Oct 7: [Electronic publication ahead of print]
5. Maier K., Merkler D., Gerber J., Taheri N., Kuhnert A.V., Williams S.K., et al. Multiple neuroprotective mechanisms of minocycline in autoimmune CNS inflammation. Neurobiol Dis 25 (2007) 514-525
6. Wang J.Q., Arora A., Yang L., Parelkar N.K., Zhang G., Liu X., et al. Phosphorylation of AMPA receptors: mechanisms and synaptic plasticity. Mol Neurobiol 32 (2005) 237-249
7. Wiedholz L.M., Owens W.A., Horton R.E., Feyder M., Karlsson R.M., Hefner K., et al. Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and 'schizophrenia-related' behaviors. Mol Psychiatry 13 (2008) 631-640
8. Woolley M.L., Waters K.A., Gartlon J.E., Lacroix L.P., Jennings C., Shaughnessy F., et al. Evaluation of the pro-cognitive effects of the AMPA receptor positive modulator, 5-(1-piperidinylcarbonyl)-2,1,3-benzoxadiazole (CX691), in the rat. Psychopharmacology (Berl) (2008) Sep 16. [Electronic publication ahead of print]