-
1
-
-
0036260089
-
Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis
-
Brundula V., Rewcastle N.B., Metz L.M., Bernard C.C., Yong V.W. Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis. Brain 2002, 125:1297-1308.
-
(2002)
Brain
, vol.125
, pp. 1297-1308
-
-
Brundula, V.1
Rewcastle, N.B.2
Metz, L.M.3
Bernard, C.C.4
Yong, V.W.5
-
2
-
-
0037007645
-
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
-
Zhu S., Stavrovskaya I.G., Drozda M., et al. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature 2002, 417:74-78.
-
(2002)
Nature
, vol.417
, pp. 74-78
-
-
Zhu, S.1
Stavrovskaya, I.G.2
Drozda, M.3
-
3
-
-
34848857092
-
Minocycline treatment in acute stroke: an open-label, evaluator-blinded study
-
Lampl Y., Boaz M., Gilad R., et al. Minocycline treatment in acute stroke: an open-label, evaluator-blinded study. Neurology 2007, 69:1404-1410.
-
(2007)
Neurology
, vol.69
, pp. 1404-1410
-
-
Lampl, Y.1
Boaz, M.2
Gilad, R.3
-
4
-
-
35948934636
-
Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis
-
Isermann B., Vinnikov I.A., Madhusudhan T., et al. Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis. Nat Med 2007, 13:1349-1358.
-
(2007)
Nat Med
, vol.13
, pp. 1349-1358
-
-
Isermann, B.1
Vinnikov, I.A.2
Madhusudhan, T.3
-
5
-
-
17844392902
-
Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy
-
Krady J.K., Basu A., Allen C.M., et al. Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy. Diabetes 2005, 54:1559-1565.
-
(2005)
Diabetes
, vol.54
, pp. 1559-1565
-
-
Krady, J.K.1
Basu, A.2
Allen, C.M.3
-
6
-
-
0141642017
-
Minocycline inhibits smooth muscle cell proliferation, migration and neointima formation after arterial injury
-
Pinney S.P., Chen H.J., Liang D., et al. Minocycline inhibits smooth muscle cell proliferation, migration and neointima formation after arterial injury. J Cardiovasc Pharmacol 2003, 42:469-476.
-
(2003)
J Cardiovasc Pharmacol
, vol.42
, pp. 469-476
-
-
Pinney, S.P.1
Chen, H.J.2
Liang, D.3
-
7
-
-
77949282627
-
Effect of an antimicrobial agent on atherosclerotic plaques: assessment of metalloproteinase activity by molecular imaging
-
Ohshima S., Fujimoto S., Petrov A., et al. Effect of an antimicrobial agent on atherosclerotic plaques: assessment of metalloproteinase activity by molecular imaging. J Am Coll Cardiol 2010, 55:1240-1249.
-
(2010)
J Am Coll Cardiol
, vol.55
, pp. 1240-1249
-
-
Ohshima, S.1
Fujimoto, S.2
Petrov, A.3
-
8
-
-
4143127785
-
Minocycline exerts multiple inhibitory effects on vascular endothelial growth factor-induced smooth muscle cell migration: the role of ERK1/2, PI3K, and matrix metalloproteinases
-
Yao J.S., Chen Y., Zhai W., et al. Minocycline exerts multiple inhibitory effects on vascular endothelial growth factor-induced smooth muscle cell migration: the role of ERK1/2, PI3K, and matrix metalloproteinases. Circ Res 2004, 95:364-371.
-
(2004)
Circ Res
, vol.95
, pp. 364-371
-
-
Yao, J.S.1
Chen, Y.2
Zhai, W.3
-
9
-
-
0038719694
-
Targeting the cell cycle machinery for the treatment of cardiovascular disease
-
Bicknell K.A., Surry E.L., Brooks G. Targeting the cell cycle machinery for the treatment of cardiovascular disease. J Pharm Pharmacol 2003, 55:571-591.
-
(2003)
J Pharm Pharmacol
, vol.55
, pp. 571-591
-
-
Bicknell, K.A.1
Surry, E.L.2
Brooks, G.3
-
10
-
-
0033019113
-
Biphasic pattern of cell turnover characterizes the progression from fatty streaks to ruptured human atherosclerotic plaques
-
Lutgens E., de Muinck E.D., Kitslaar P.J., et al. Biphasic pattern of cell turnover characterizes the progression from fatty streaks to ruptured human atherosclerotic plaques. Cardiovasc Res 1999, 41:473-479.
-
(1999)
Cardiovasc Res
, vol.41
, pp. 473-479
-
-
Lutgens, E.1
de Muinck, E.D.2
Kitslaar, P.J.3
-
11
-
-
77952709281
-
Minocycline inhibits glial proliferation in the H-Tx rat model of congenital hydrocephalus
-
McAllister J.P., Miller J.M. Minocycline inhibits glial proliferation in the H-Tx rat model of congenital hydrocephalus. Cerebrospinal Fluid Res 2010, 7:7.
-
(2010)
Cerebrospinal Fluid Res
, vol.7
, pp. 7
-
-
McAllister, J.P.1
Miller, J.M.2
-
12
-
-
0034855964
-
The growth suppressor p27(Kip1) protects against diet-induced atherosclerosis
-
Diez-Juan A., Andres V. The growth suppressor p27(Kip1) protects against diet-induced atherosclerosis. FASEB J 2001, 15:1989-1995.
-
(2001)
FASEB J
, vol.15
, pp. 1989-1995
-
-
Diez-Juan, A.1
Andres, V.2
-
13
-
-
0037180771
-
Inflammation in atherosclerosis
-
Libby P. Inflammation in atherosclerosis. Nature 2002, 420:868-874.
-
(2002)
Nature
, vol.420
, pp. 868-874
-
-
Libby, P.1
-
14
-
-
0028931265
-
Principles of CDK regulation
-
Morgan D.O. Principles of CDK regulation. Nature 1995, 374:131-134.
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
15
-
-
0034595296
-
Differential effects of the cyclin-dependent kinase inhibitors p27(Kip1), p21(Cip1), and p16(Ink4) on vascular smooth muscle cell proliferation
-
Tanner F.C., Boehm M., Akyurek L.M., et al. Differential effects of the cyclin-dependent kinase inhibitors p27(Kip1), p21(Cip1), and p16(Ink4) on vascular smooth muscle cell proliferation. Circulation 2000, 101:2022-2025.
-
(2000)
Circulation
, vol.101
, pp. 2022-2025
-
-
Tanner, F.C.1
Boehm, M.2
Akyurek, L.M.3
-
16
-
-
54049134395
-
Poly(ADP-ribosyl)ation is implicated in the G0-G1 transition of resting cells
-
Carbone M., Rossi M.N., Cavaldesi M., et al. Poly(ADP-ribosyl)ation is implicated in the G0-G1 transition of resting cells. Oncogene 2008, 27:6083-6092.
-
(2008)
Oncogene
, vol.27
, pp. 6083-6092
-
-
Carbone, M.1
Rossi, M.N.2
Cavaldesi, M.3
-
17
-
-
33745457705
-
Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations
-
Alano C.C., Kauppinen T.M., Valls A.V., Swanson R.A. Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations. Proc Natl Acad Sci U S A 2006, 103:9685-9690.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 9685-9690
-
-
Alano, C.C.1
Kauppinen, T.M.2
Valls, A.V.3
Swanson, R.A.4
-
18
-
-
70349330117
-
Frommhold, D., Nawroth, P.P. and Isermann, B., Hypercoagulability inhibits monocyte transendothelial migration through protease-activated receptor-1-, phospholipase-Cbeta-, phosphoinositide 3-kinase-, and nitric oxide-dependent signaling in monocytes and promotes plaque stability
-
Seehaus S., Shahzad K., Kashif M., et al. Frommhold, D., Nawroth, P.P. and Isermann, B., Hypercoagulability inhibits monocyte transendothelial migration through protease-activated receptor-1-, phospholipase-Cbeta-, phosphoinositide 3-kinase-, and nitric oxide-dependent signaling in monocytes and promotes plaque stability. Circulation 2009, 120:774-784.
-
(2009)
Circulation
, vol.120
, pp. 774-784
-
-
Seehaus, S.1
Shahzad, K.2
Kashif, M.3
-
19
-
-
0033669676
-
Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouse
-
Rosenfeld M.E., Polinsky P., Virmani R., et al. Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouse. Arterioscler Thromb Vasc Biol 2000, 20:2587-2592.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 2587-2592
-
-
Rosenfeld, M.E.1
Polinsky, P.2
Virmani, R.3
-
20
-
-
33846588942
-
Comparison of doxycycline and minocycline in the inhibition of VEGF-induced smooth muscle cell migration
-
Yao J.S., Shen F., Young W.L., Yang G.Y. Comparison of doxycycline and minocycline in the inhibition of VEGF-induced smooth muscle cell migration. Neurochem Int 2007, 50:524-530.
-
(2007)
Neurochem Int
, vol.50
, pp. 524-530
-
-
Yao, J.S.1
Shen, F.2
Young, W.L.3
Yang, G.Y.4
-
21
-
-
0036118347
-
Doxycycline modulates smooth muscle cell growth, migration, and matrix remodeling after arterial injury
-
Bendeck M.P., Conte M., Zhang M., et al. Doxycycline modulates smooth muscle cell growth, migration, and matrix remodeling after arterial injury. Am J Pathol 2002, 160:1089-1095.
-
(2002)
Am J Pathol
, vol.160
, pp. 1089-1095
-
-
Bendeck, M.P.1
Conte, M.2
Zhang, M.3
-
22
-
-
70349731911
-
Minocycline attenuates 5-fluorouracil-induced small intestinal mucositis in mouse model
-
Huang T.Y., Chu H.C., Lin Y.L., et al. Minocycline attenuates 5-fluorouracil-induced small intestinal mucositis in mouse model. Biochem Biophys Res Commun 2009, 389:634-639.
-
(2009)
Biochem Biophys Res Commun
, vol.389
, pp. 634-639
-
-
Huang, T.Y.1
Chu, H.C.2
Lin, Y.L.3
-
23
-
-
0035871840
-
Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
-
Tikka T., Fiebich B.L., Goldsteins G., Keinanen R., Koistinaho J. Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J Neurosci 2001, 21:2580-2588.
-
(2001)
J Neurosci
, vol.21
, pp. 2580-2588
-
-
Tikka, T.1
Fiebich, B.L.2
Goldsteins, G.3
Keinanen, R.4
Koistinaho, J.5
-
24
-
-
0031281806
-
Inhibition of proliferation and induction of apoptosis by doxycycline in cultured human osteosarcoma cells
-
Fife R.S., Rougraff B.T., Proctor C., Sledge G.W. Inhibition of proliferation and induction of apoptosis by doxycycline in cultured human osteosarcoma cells. J Lab Clin Med 1997, 130:530-534.
-
(1997)
J Lab Clin Med
, vol.130
, pp. 530-534
-
-
Fife, R.S.1
Rougraff, B.T.2
Proctor, C.3
Sledge, G.W.4
-
25
-
-
0029257434
-
Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells
-
Fife R.S., Sledge G.W. Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells. J Lab Clin Med 1995, 125:407-411.
-
(1995)
J Lab Clin Med
, vol.125
, pp. 407-411
-
-
Fife, R.S.1
Sledge, G.W.2
-
26
-
-
70350159878
-
Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis
-
Orr A.W., Hastings N.E., Blackman B.R., Wamhoff B.R. Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis. J Vasc Res 2010, 47:168-180.
-
(2010)
J Vasc Res
, vol.47
, pp. 168-180
-
-
Orr, A.W.1
Hastings, N.E.2
Blackman, B.R.3
Wamhoff, B.R.4
-
27
-
-
0032559554
-
Expression of cyclin-dependent kinase inhibitors in vascular disease
-
Tanner F.C., Yang Z.Y., Duckers E., et al. Expression of cyclin-dependent kinase inhibitors in vascular disease. Circ Res 1998, 82:396-403.
-
(1998)
Circ Res
, vol.82
, pp. 396-403
-
-
Tanner, F.C.1
Yang, Z.Y.2
Duckers, E.3
-
28
-
-
64049087377
-
Regulation of FOXO1-mediated transcription and cell proliferation by PARP-1
-
Sakamaki J., Daitoku H., Yoshimochi K., Miwa M., Fukamizu A. Regulation of FOXO1-mediated transcription and cell proliferation by PARP-1. Biochem Biophys Res Commun 2009, 382:497-502.
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 497-502
-
-
Sakamaki, J.1
Daitoku, H.2
Yoshimochi, K.3
Miwa, M.4
Fukamizu, A.5
-
29
-
-
23844491841
-
Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia
-
Abid M.R., Yano K., Guo S., et al. Forkhead transcription factors inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia. J Biol Chem 2005, 280:29864-29873.
-
(2005)
J Biol Chem
, vol.280
, pp. 29864-29873
-
-
Abid, M.R.1
Yano, K.2
Guo, S.3
-
30
-
-
0030885556
-
The molecular bases of restenosis
-
Libby P., Tanaka H. The molecular bases of restenosis. Prog Cardiovasc Dis 1997, 40:97-106.
-
(1997)
Prog Cardiovasc Dis
, vol.40
, pp. 97-106
-
-
Libby, P.1
Tanaka, H.2
-
31
-
-
34248178529
-
Poly(ADP-ribose) polymerase inhibition reduces atherosclerotic plaque size and promotes factors of plaque stability in apolipoprotein E-deficient mice: effects on macrophage recruitment, nuclear factor-kappaB nuclear translocation, and foam cell death
-
Oumouna-Benachour K., Hans C.P., Suzuki Y., et al. Poly(ADP-ribose) polymerase inhibition reduces atherosclerotic plaque size and promotes factors of plaque stability in apolipoprotein E-deficient mice: effects on macrophage recruitment, nuclear factor-kappaB nuclear translocation, and foam cell death. Circulation 2007, 115:2442-2450.
-
(2007)
Circulation
, vol.115
, pp. 2442-2450
-
-
Oumouna-Benachour, K.1
Hans, C.P.2
Suzuki, Y.3
-
32
-
-
42749084898
-
Combined treatment with atorvastatin and minocycline suppresses severity of EAE
-
Luccarini I., Ballerini C., Biagioli T., et al. Combined treatment with atorvastatin and minocycline suppresses severity of EAE. Exp Neurol 2008, 211:214-226.
-
(2008)
Exp Neurol
, vol.211
, pp. 214-226
-
-
Luccarini, I.1
Ballerini, C.2
Biagioli, T.3
|