Targeting the pregnane X receptor in liver injury

Expert Opinion on Therapeutic Targets

Volumn 16, Issue 11, 2012, Pages 1075-1083

  Li, Tao ^a   Yu, Ruth T ^a   Atkins, Annette R ^a   Downes, Michael ^a   Tukey, Robert H ^b   Evans, Ronald M ^c  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b San Diego   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Drug target; Liver injury; Nuclear receptor; PXR; Xenobiotic

Indexed keywords

1,4 BIS(3,5 DICHLORO 2 PYRIDYLOXY)BENZENE; 4,4' ISOPROPYLIDENEDIPHENOL; CAFESTOL; CHLORDANE; CLOFIBRATE; CLOTRIMAZOLE; CORTICOSTERONE; COUMESTROL; DIELDRIN; DIETHYLSTILBESTROL; ENDOSULFAN; ESTRADIOL; FLUCLOXACILLIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPERFORIN; HYPOCHOLESTEROLEMIC AGENT; PACLITAXEL; PARACETAMOL; PERFLUORODECANOIC ACID; PHENOBARBITAL; PHYTOESTROGEN; PREGNANE X RECEPTOR; RIFAMPICIN; SR 12813; TACROLIMUS; TETRACYCLINE; TRABECTEDIN; TROGLITAZONE; UNCLASSIFIED DRUG; UNINDEXED DRUG; XENOBIOTIC AGENT;

ACUTE LIVER FAILURE; CHRONIC LIVER DISEASE; DRUG CLEARANCE; DRUG METABOLISM; DRUG TARGETING; ENDOCRINE DISEASE; GENETIC POLYMORPHISM; HEPATITIS; HUMAN; IN VITRO STUDY; LIVER INJURY; LIVER PROTECTION; NONHUMAN; PHARMACOGENETICS; REVIEW;

ANIMALS; HUMANS; LIVER; LIVER DISEASES; PHARMACEUTICAL PREPARATIONS; RECEPTORS, STEROID;

EID: 84867562647     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2012.715634     Document Type: Review

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