Effect of pregnane X receptor ligand on pharmacokinetics of substrates of organic cation transporter Oct1 in rats

Drug Metabolism and Disposition

Volumn 35, Issue 9, 2007, Pages 1580-1586

  Maeda, Tomoji ^a   Oyabu, Masanobu ^a   Yotsumoto, Takafumi ^a   Higashi, Ryunosuke ^a   Nagata, Kiyoshi ^b   Yamazoe, Yasushi ^c   Tamai, Ikumi ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 16ALPHA CYANOPREGNENOLONE; CELL NUCLEUS RECEPTOR; MESSENGER RNA; METFORMIN; ORGANIC CATION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 2; PREGNANE X RECEPTOR; TETRYLAMMONIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BILIARY EXCRETION; CELL CULTURE; CELL ISOLATION; CONTROLLED STUDY; DISTRIBUTION VOLUME; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION;

ANIMALS; AREA UNDER CURVE; CATIONS; CELL SEPARATION; CELLS, CULTURED; DIGOXIN; HEPATOCYTES; KINETICS; LIGANDS; LIVER; MALE; ORGANIC CATION TRANSPORTER 1; PHARMACEUTICAL PREPARATIONS; PREGNENOLONE CARBONITRILE; RATS; RATS, WISTAR; RECEPTORS, STEROID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFECTION; TRICHLOROACETIC ACID;

RATTUS;

EID: 34548059857     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.015842     Document Type: Article

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