-
1
-
-
0032879904
-
MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs
-
Schuetz, J. D., Connelly, M. C., Sun, D., Paibir, S. G., Flynn, P. M., Srinivas, R. V., Kumar, A., Fridland, A. "MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs." Nat Med 1999; 5(9): 1048-1051.
-
(1999)
Nat Med
, vol.5
, Issue.9
, pp. 1048-1051
-
-
Schuetz, J.D.1
Connelly, M.C.2
Sun, D.3
Paibir, S.G.4
Flynn, P.M.5
Srinivas, R.V.6
Kumar, A.7
Fridland, A.8
-
2
-
-
0037705377
-
Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells
-
Wielinga, P. R., I. van der Heijden, I., Reid, G., Beijnen, J. H., Wijnholds, J., Borst, P. "Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells." J Biol Chem 2003; 278(20): 17664-17671.
-
(2003)
J Biol Chem
, vol.278
, Issue.20
, pp. 17664-17671
-
-
Wielinga, P.R.1
Reid, G.2
Beijnen, J.H.3
Wijnholds, J.4
Borst, P.5
-
3
-
-
0037693882
-
Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4)
-
Zelcer, N., Reid, G., Wielinga, P., Kuil, A., van der Heijden, I., Schuetz, J. D., Borst, P. "Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4)." Biochem J 2003; 371(Pt 2): 361-367.
-
(2003)
Biochem J
, vol.371
, Issue.Pt 2
, pp. 361-367
-
-
Zelcer, N.1
Reid, G.2
Wielinga, P.3
Kuil, A.4
van der Heijden, I.5
Schuetz, J.D.6
Borst, P.7
-
4
-
-
0036074018
-
Mammalian ABC transporters in health and disease
-
Borst, P. and R. O. Elferink. "Mammalian ABC transporters in health and disease." Annu Rev Biochem 2002; 71: 537-592.
-
(2002)
Annu Rev Biochem
, vol.71
, pp. 537-592
-
-
Borst, P.1
Elferink, R.O.2
-
5
-
-
0036186107
-
The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP
-
van Aubel, R. A., Smeets, P. H., Peters, J. G., Bindels, R. J., Russel, F. G. "The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP." J Am Soc Nephrol 2002; 13(3): 595-603.
-
(2002)
J Am Soc Nephrol
, vol.13
, Issue.3
, pp. 595-603
-
-
van Aubel, R.A.1
Smeets, P.H.2
Peters, J.G.3
Bindels, R.J.4
Russel, F.G.5
-
6
-
-
0042766881
-
Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane
-
Rius, M., Nies, A. T., Hummel-Eisenbeiss, J., Jedlitschky, G., Keppler, D. "Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane." Hepatology 2003; 38(2): 374-384.
-
(2003)
Hepatology
, vol.38
, Issue.2
, pp. 374-384
-
-
Rius, M.1
Nies, A.T.2
Hummel-Eisenbeiss, J.3
Jedlitschky, G.4
Keppler, D.5
-
7
-
-
33645825217
-
Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione
-
Rius, M., Hummel-Eisenbeiss, J., Hofmann, A. F., Keppler, D. "Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione." Am J Physiol Gastrointest Liver Physiol 2006; 290(4): G640-649.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
, Issue.4
-
-
Rius, M.1
Hummel-Eisenbeiss, J.2
Hofmann, A.F.3
Keppler, D.4
-
8
-
-
6344265573
-
Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain
-
Nies, A. T., Jedlitschky, G. Konig, J., Herold-Mende, C., Steiner, H. H., Schmitt, H. P., Keppler, D. "Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain." Neuroscience 2004; 129(2): 349-360.
-
(2004)
Neuroscience
, vol.129
, Issue.2
, pp. 349-360
-
-
Nies, A.T.1
Jedlitschky, G.2
Konig, J.3
Herold-Mende, C.4
Steiner, H.H.5
Schmitt, H.P.6
Keppler, D.7
-
9
-
-
18644378003
-
Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma
-
Konig, J., Hartel, M., Nies, A. T., Martignoni, M. E., Guo, J., Buchler, M. W., Friess, H., Keppler, D. "Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma." Int J Cancer 2005; 115(3): 359-367.
-
(2005)
Int J Cancer
, vol.115
, Issue.3
, pp. 359-367
-
-
Konig, J.1
Hartel, M.2
Nies, A.T.3
Martignoni, M.E.4
Guo, J.5
Buchler, M.W.6
Friess, H.7
Keppler, D.8
-
10
-
-
0141447401
-
cGMP and glutathione-conjugate transport in human erythrocytes
-
Klokouzas, A., Wu, C. P., van Veen, H. W., Barrand, M. A., Hladky, S. B. "cGMP and glutathione-conjugate transport in human erythrocytes." Eur J Biochem 2003; 270(18): 3696-3708.
-
(2003)
Eur J Biochem
, vol.270
, Issue.18
, pp. 3696-3708
-
-
Klokouzas, A.1
Wu, C.P.2
van Veen, H.W.3
Barrand, M.A.4
Hladky, S.B.5
-
11
-
-
9444248147
-
The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage
-
Jedlitschky, G., Tirschmann, K., Lubenow, L. E., Nieuwenhuis, H. K., Akkerman, J. W., Greinacher, A., Kroemer, H. K. "The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage." Blood 2004; 104(12): 3603-3610.
-
(2004)
Blood
, vol.104
, Issue.12
, pp. 3603-3610
-
-
Jedlitschky, G.1
Tirschmann, K.2
Lubenow, L.E.3
Nieuwenhuis, H.K.4
Akkerman, J.W.5
Greinacher, A.6
Kroemer, H.K.7
-
12
-
-
0034614112
-
Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells
-
Lee, K., A. J. Klein-Szanto, Kruh, G. D. "Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells." J Natl Cancer Inst 2000; 92(23): 1934-1940.
-
(2000)
J Natl Cancer Inst
, vol.92
, Issue.23
, pp. 1934-1940
-
-
Lee, K.1
Klein-Szanto, A.J.2
Kruh, G.D.3
-
13
-
-
12144269640
-
Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter
-
Smeets, P. H., van Aubel, R. A., Wouterse, A. C., van den Heuvel, J. J., Russel, F. G. "Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter." J Am Soc Nephrol 2004; 15(11): 2828-2835.
-
(2004)
J Am Soc Nephrol
, vol.15
, Issue.11
, pp. 2828-2835
-
-
Smeets, P.H.1
van Aubel, R.A.2
Wouterse, A.C.3
van den Heuvel, J.J.4
Russel, F.G.5
-
14
-
-
0035823559
-
Transport of cyclic nucleotides and estradiol 17-beta-d-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine
-
Chen, Z. S., K. Lee, Kruh, G. D. "Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine." J Biol Chem 2001; 276(36): 33747-33754.
-
(2001)
J Biol Chem
, vol.276
, Issue.36
, pp. 33747-33754
-
-
Chen, Z.S.1
Lee, K.2
Kruh, G.D.3
-
15
-
-
0036893815
-
Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells
-
Wielinga, P. R., Reid, G., Challa, E. E., van der Heijden, I., van Deemter, L., de Haas, M., Mol, C., Kuil, A. J., Groeneveld, E., Schuetz, J. D., Brouwer, C., De Abreu, R. A., Wijnholds, J., Beijnen, J. H., Borst, P. "Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells." Mol Pharmacol 2002; 62(6): 1321-1331.
-
(2002)
Mol Pharmacol
, vol.62
, Issue.6
, pp. 1321-1331
-
-
Wielinga, P.R.1
Reid, G.2
Challa, E.E.3
van der Heijden, I.4
van Deemter, L.5
de Haas, M.6
Mol, C.7
Kuil, A.J.8
Groeneveld, E.9
Schuetz, J.D.10
Brouwer, C.11
de Abreu, R.A.12
Wijnholds, J.13
Beijnen, J.H.14
Borst, P.15
-
16
-
-
1642316825
-
Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat
-
Denk, G. U., Soroka, C. J., Takeyama, Y., Chen, W. S., Schuetz, J. D., Boyer, J. L. "Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat." J Hepatol 2004; 40(4): 585-591.
-
(2004)
J Hepatol
, vol.40
, Issue.4
, pp. 585-591
-
-
Denk, G.U.1
Soroka, C.J.2
Takeyama, Y.3
Chen, W.S.4
Schuetz, J.D.5
Boyer, J.L.6
-
17
-
-
37149046027
-
Obstructive cholestasis induces TNF-alpha- and IL-1 -mediated periportal downregulation of Bsep and zonal regulation of Ntcp, Oatp1a4, and Oatp1b2
-
Donner, M. G., Schumacher, S., Warskulat, U., Heinemann, J., Haussinger, D. "Obstructive cholestasis induces TNF-alpha- and IL-1 -mediated periportal downregulation of Bsep and zonal regulation of Ntcp, Oatp1a4, and Oatp1b2." Am J Physiol Gastrointest Liver Physiol 2007; 293(6): G1134-1146.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.293
, Issue.6
-
-
Donner, M.G.1
Schumacher, S.2
Warskulat, U.3
Heinemann, J.4
Haussinger, D.5
-
18
-
-
0042825756
-
Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice
-
Wagner, M., Fickert, P., Zollner, G., Fuchsbichler, A., Silbert, D., Tsybrovskyy, O., Zatloukal, K., Guo, G. L., Schuetz, J. D., Gonzalez, F. J., Marschall, H. U., Denk, H., Trauner, M. "Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice." Gastroenterology 2003; 125(3): 825-838.
-
(2003)
Gastroenterology
, vol.125
, Issue.3
, pp. 825-838
-
-
Wagner, M.1
Fickert, P.2
Zollner, G.3
Fuchsbichler, A.4
Silbert, D.5
Tsybrovskyy, O.6
Zatloukal, K.7
Guo, G.L.8
Schuetz, J.D.9
Gonzalez, F.J.10
Marschall, H.U.11
Denk, H.12
Trauner, M.13
-
19
-
-
0035080391
-
Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver
-
Soroka, C. J., Lee, J. M., Azzaroli, F., Boyer, J. L. "Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver." Hepatology 2001; 33(4): 783-791.
-
(2001)
Hepatology
, vol.33
, Issue.4
, pp. 783-791
-
-
Soroka, C.J.1
Lee, J.M.2
Azzaroli, F.3
Boyer, J.L.4
-
20
-
-
0034928631
-
Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver
-
Donner, M. G. and D. Keppler. "Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver." Hepatology 2001; 34(2): 351-359.
-
(2001)
Hepatology
, vol.34
, Issue.2
, pp. 351-359
-
-
Donner, M.G.1
Keppler, D.2
-
21
-
-
0141814990
-
Tumor necrosis factor alpha-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis
-
Bohan, A., Chen, W. S., Denson, L. A., Held, M. A., Boyer, J. L. "Tumor necrosis factor alpha-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis." J Biol Chem 2003; 278(38): 36688-36698.
-
(2003)
J Biol Chem
, vol.278
, Issue.38
, pp. 36688-36698
-
-
Bohan, A.1
Chen, W.S.2
Denson, L.A.3
Held, M.A.4
Boyer, J.L.5
-
22
-
-
33646871585
-
Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents
-
Boyer, J. L., Trauner, M., Mennone, A., Soroka, C. J., Cai, S. Y., Moustafa, T., Zollner, G., Lee, J. Y., Ballatori, N. "Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents." Am J Physiol Gastrointest Liver Physiol 2006; 290(6): G1124-1130.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
, Issue.6
-
-
Boyer, J.L.1
Trauner, M.2
Mennone, A.3
Soroka, C.J.4
Cai, S.Y.5
Moustafa, T.6
Zollner, G.7
Lee, J.Y.8
Ballatori, N.9
-
23
-
-
33644910207
-
Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides
-
Zelcer, N., van de Wetering, K., de Waart, R., Scheffer, G. L., Marschall, H. U., Wielinga, P. R., Kuil, A., Kunne, C., Smith, A., van der Valk, M., Wijnholds, J., Elferink, R. O., Borst, P. "Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides." J Hepatol 2006; 44(4): 768-775.
-
(2006)
J Hepatol
, vol.44
, Issue.4
, pp. 768-775
-
-
Zelcer, N.1
van de Wetering, K.2
de Waart, R.3
Scheffer, G.L.4
Marschall, H.U.5
Wielinga, P.R.6
Kuil, A.7
Kunne, C.8
Smith, A.9
van der Valk, M.10
Wijnholds, J.11
Elferink, R.O.12
Borst, P.13
-
24
-
-
33646541411
-
Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis
-
Mennone, A., Soroka, C. J., Cai, S. Y., Harry, K., Adachi, M., Hagey, L., Schuetz, J. D., Boyer, J. L. Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis. Hepatology 2006; 43: 1013-21.
-
(2006)
Hepatology
, vol.43
, pp. 1013-1021
-
-
Mennone, A.1
Soroka, C.J.2
Cai, S.Y.3
Harry, K.4
Adachi, M.5
Hagey, L.6
Schuetz, J.D.7
Boyer, J.L.8
-
25
-
-
33645839049
-
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids
-
Zollner, G., Wagner, M., Moustafa, T., Fickert, P., Silbert, D., Gumhold, J., Fuchsbichler, A., Halilbasic, E., Denk, H., Marschall, H. U., Trauner, M. "Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids." Am J Physiol Gastrointest Liver Physiol 2006; 290(5): G923-932.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
, Issue.5
-
-
Zollner, G.1
Wagner, M.2
Moustafa, T.3
Fickert, P.4
Silbert, D.5
Gumhold, J.6
Fuchsbichler, A.7
Halilbasic, E.8
Denk, H.9
Marschall, H.U.10
Trauner, M.11
-
26
-
-
0036328387
-
Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital
-
Xiong, H., Yoshinari, K., Brouwer, K. L., Negishi, M. "Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital." Drug Metab Dispos 2002; 30(8): 918-923.
-
(2002)
Drug Metab Dispos
, vol.30
, Issue.8
, pp. 918-923
-
-
Xiong, H.1
Yoshinari, K.2
Brouwer, K.L.3
Negishi, M.4
-
27
-
-
22344433760
-
Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver
-
Maher, J. M., Cheng, X., Slitt, A. L., Dieter, M. Z., Klaassen, C. D. "Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver." Drug Metab Dispos 2005; 33(7): 956-962.
-
(2005)
Drug Metab Dispos
, vol.33
, Issue.7
, pp. 956-962
-
-
Maher, J.M.1
Cheng, X.2
Slitt, A.L.3
Dieter, M.Z.4
Klaassen, C.D.5
-
28
-
-
34748821996
-
Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport
-
Petrick, J. S. and C. D. Klaassen. "Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport." Drug Metab Dispos 2007; 35(10): 1806-1815.
-
(2007)
Drug Metab Dispos
, vol.35
, Issue.10
, pp. 1806-1815
-
-
Petrick, J.S.1
Klaassen, C.D.2
-
29
-
-
13844315320
-
Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury
-
Stedman, C. A., Liddle, C., Coulter, S. A., Sonoda, J., Alvarez, J. G., Moore, D. D., Evans, R. M., Downes, M. "Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury." Proc Natl Acad Sci U S A 2005; 102(6): 2063-2068.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.6
, pp. 2063-2068
-
-
Stedman, C.A.1
Liddle, C.2
Coulter, S.A.3
Sonoda, J.4
Alvarez, J.G.5
Moore, D.D.6
Evans, R.M.7
Downes, M.8
-
30
-
-
0037169551
-
Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor
-
Kast, H. R., Goodwin, B., Tarr, P. T., Jones, S. A., Anisfeld, A. M., Stoltz, C. M., Tontonoz, P., Kliewer, S., Willson, T. M., Edwards, P. A. "Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor." J Biol Chem 2002; 277(4): 2908-2915.
-
(2002)
J Biol Chem
, vol.277
, Issue.4
, pp. 2908-2915
-
-
Kast, H.R.1
Goodwin, B.2
Tarr, P.T.3
Jones, S.A.4
Anisfeld, A.M.5
Stoltz, C.M.6
Tontonoz, P.7
Kliewer, S.8
Willson, T.M.9
Edwards, P.A.10
-
31
-
-
23044436687
-
CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice
-
Wagner, M., Halilbasic, E., Marschall, H. U., Zollner, G., Fickert, P., Langner, C., Zatloukal, K., Denk, H., Trauner, M. "CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice." Hepatology 2005; 42(2): 420-430.
-
(2005)
Hepatology
, vol.42
, Issue.2
, pp. 420-430
-
-
Wagner, M.1
Halilbasic, E.2
Marschall, H.U.3
Zollner, G.4
Fickert, P.5
Langner, C.6
Zatloukal, K.7
Denk, H.8
Trauner, M.9
-
32
-
-
2542440464
-
Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice
-
Assem, M., Schuetz, E. G., Leggas, M., Sun, D., Yasuda, K., Reid, G., Zelcer, N., Adachi, M., Strom, S., Evans, R. M., Moore, D. D., Borst, P., Schuetz, J. D. "Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice." J Biol Chem 2004; 279(21): 22250-22257.
-
(2004)
J Biol Chem
, vol.279
, Issue.21
, pp. 22250-22257
-
-
Assem, M.1
Schuetz, E.G.2
Leggas, M.3
Sun, D.4
Yasuda, K.5
Reid, G.6
Zelcer, N.7
Adachi, M.8
Strom, S.9
Evans, R.M.10
Moore, D.D.11
Borst, P.12
Schuetz, J.D.13
-
33
-
-
0034035667
-
Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver
-
Wan, Y. J., An, D., Cai, Y., Repa, J. J., Hung-Po Chen, T., Flores, M., Postic, C., Magnuson, M. A., Chen, J., Chien, K. R., French, S., Mangelsdorf, D. J., Sucov, H. M. "Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver." Mol Cell Biol 2000; 20(12): 4436-4444.
-
(2000)
Mol Cell Biol
, vol.20
, Issue.12
, pp. 4436-4444
-
-
Wan, Y.J.1
An, D.2
Cai, Y.3
Repa, J.J.4
Hung-Po Chen, T.5
Flores, M.6
Postic, C.7
Magnuson, M.A.8
Chen, J.9
Chien, K.R.10
French, S.11
Mangelsdorf, D.J.12
Sucov, H.M.13
-
34
-
-
67649208211
-
Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice
-
Cui, Y. J., Aleksunes, L. M., Tanaka, Y., Goedken, M. J., Klaassen, C. D. "Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice." Toxicol Sci 2009; 110(1): 47-60.
-
(2009)
Toxicol Sci
, vol.110
, Issue.1
, pp. 47-60
-
-
Cui, Y.J.1
Aleksunes, L.M.2
Tanaka, Y.3
Goedken, M.J.4
Klaassen, C.D.5
-
35
-
-
11244327692
-
Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice
-
Uppal, H., Toma, D., Saini, S. P., Ren, S., Jones, T. J., Xie, W. "Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice." Hepatology 2005; 41(1): 168-176.
-
(2005)
Hepatology
, vol.41
, Issue.1
, pp. 168-176
-
-
Uppal, H.1
Toma, D.2
Saini, S.P.3
Ren, S.4
Jones, T.J.5
Xie, W.6
-
36
-
-
70350407482
-
Association of pregnane X receptor with multidrug resistance-related protein 3 and its role in human colon cancer chemoresistance
-
Jiang, H., Chen, K., He, J., Pan, F., Li, J., Chen, J., Chen, W., Liang, H. "Association of pregnane X receptor with multidrug resistance-related protein 3 and its role in human colon cancer chemoresistance." J Gastrointest Surg 2009; 13(10): 1831-1838.
-
(2009)
J Gastrointest Surg
, vol.13
, Issue.10
, pp. 1831-1838
-
-
Jiang, H.1
Chen, K.2
He, J.3
Pan, F.4
Li, J.5
Chen, J.6
Chen, W.7
Liang, H.8
-
37
-
-
67349105004
-
Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor
-
Harmsen, S., Meijerman, I., Beijnen, J. H., Schellens, J. H. "Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor." Cancer Chemother Pharmacol 2009; 64(1): 35-43.
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, Issue.1
, pp. 35-43
-
-
Harmsen, S.1
Meijerman, I.2
Beijnen, J.H.3
Schellens, J.H.4
-
38
-
-
65449177586
-
High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis
-
Schaap, F. G., van der Gaag, N. A., Gouma, D. J., Jansen, P. L. "High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis." Hepatology 2009; 49(4): 1228-1235.
-
(2009)
Hepatology
, vol.49
, Issue.4
, pp. 1228-1235
-
-
Schaap, F.G.1
van der Gaag, N.A.2
Gouma, D.J.3
Jansen, P.L.4
-
39
-
-
34547870567
-
Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis
-
Zollner, G., Wagner, M., Fickert, P., Silbert, D., Gumhold, J., Zatloukal, K., Denk, H., Trauner, M. "Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis." Liver Int 2007; 27(7): 920-929.
-
(2007)
Liver Int
, vol.27
, Issue.7
, pp. 920-929
-
-
Zollner, G.1
Wagner, M.2
Fickert, P.3
Silbert, D.4
Gumhold, J.5
Zatloukal, K.6
Denk, H.7
Trauner, M.8
-
40
-
-
78149279835
-
The impact of resuscitated fecal peritonitis on the expression of the hepatic bile salt transporters in a porcine model
-
Wauters, J., Mesotten, D., van Zwam, K., van Pelt, J., Thiessen, S., Dieudonne, A. S., Vander Borght, S., van den Berghe, G., Wilmer, A. "The impact of resuscitated fecal peritonitis on the expression of the hepatic bile salt transporters in a porcine model." Shock 2010; 34(5): 508-516.
-
(2010)
Shock
, vol.34
, Issue.5
, pp. 508-516
-
-
Wauters, J.1
Mesotten, D.2
van Zwam, K.3
van Pelt, J.4
Thiessen, S.5
Dieudonne, A.S.6
Vander Borght, S.7
van den Berghe, G.8
Wilmer, A.9
-
41
-
-
31144459322
-
Coordinated expression of multidrug resistance-associated proteins (Mrps) in mouse liver during toxicant-induced injury
-
Aleksunes, L. M., Scheffer, G. L., Jakowski, A. B., Pruimboom-Brees, I. M., Manautou, J. E. "Coordinated expression of multidrug resistance-associated proteins (Mrps) in mouse liver during toxicant-induced injury." Toxicol Sci 2006; 89(2): 370-379.
-
(2006)
Toxicol Sci
, vol.89
, Issue.2
, pp. 370-379
-
-
Aleksunes, L.M.1
Scheffer, G.L.2
Jakowski, A.B.3
Pruimboom-Brees, I.M.4
Manautou, J.E.5
-
42
-
-
0035853057
-
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids
-
Xie, W., Radominska-Pandya, A., Shi, Y., Simon, C. M., Nelson, M. C., Ong, E. S., Waxman, D. J., Evans, R. M. "An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids." Proc Natl Acad Sci U S A 2001; 98(6): 3375-3380.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.6
, pp. 3375-3380
-
-
Xie, W.1
Radominska-Pandya, A.2
Shi, Y.3
Simon, C.M.4
Nelson, M.C.5
Ong, E.S.6
Waxman, D.J.7
Evans, R.M.8
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