Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice

Hepatology

Volumn 56, Issue 2, 2012, Pages 658-667

  Chen, Shujuan ^a   Yueh, Mei Fei ^a   Evans, Ronald M ^b   Tukey, Robert H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; CONSTITUTIVE ANDROSTANE RECEPTOR; DEXAMETHASONE; GLUCOCORTICOID; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 1A4; GLUCURONOSYLTRANSFERASE 1A6; GLUCURONOSYLTRANSFERASE 1A9; PREGNANE X RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BILIRUBIN BLOOD LEVEL; BILIRUBIN METABOLISM; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE DELETION; GENE EXPRESSION; GENE LOCUS; GENE REPRESSION; GENE SILENCING; GLUCURONIDATION; HYPERBILIRUBINEMIA; MALE; MOUSE; NEWBORN; NONHUMAN; PERINATAL DEVELOPMENT; PREGNANCY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SECOND TRIMESTER PREGNANCY; THIRD TRIMESTER PREGNANCY; TRANSACTIVATION;

ANIMALS; ANIMALS, NEWBORN; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCURONIC ACID; GLUCURONOSYLTRANSFERASE; HEPATOCYTES; HUMANS; INFANT, NEWBORN; JAUNDICE, NEONATAL; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PREGNANCY; PREGNANCY COMPLICATIONS; PRIMARY CELL CULTURE; RECEPTORS, STEROID; RNA, SMALL INTERFERING; STEROIDS;

EID: 84864348294     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25671     Document Type: Article

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