Orphan Nuclear Receptors: The Exotics of Xenobiotics

Journal of Biological Chemistry

Volumn 276, Issue 41, 2001, Pages 37739-37742

  Xie, Wen ^b   Evans, Ronald M ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA CYANOPREGNENOLONE; CELL NUCLEUS RECEPTOR; CYCLOSPORIN; DEXAMETHASONE; FIBRIC ACID DERIVATIVE; GLUCOCORTICOID; HYPERICUM PERFORATUM EXTRACT; INDINAVIR; ORAL CONTRACEPTIVE AGENT; ORPHAN NUCLEAR RECEPTOR; PACLITAXEL; PHENOBARBITAL; PREGNANE X RECEPTOR; RETINOIC ACID; RIFAMPICIN; STEROID AND XENOBIOTIC RECEPTOR; THYROID HORMONE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT; ZOXAZOLAMINE; CELL RECEPTOR;

DRUG CLEARANCE; DRUG DESIGN; DRUG METABOLISM; ENZYME INDUCTION; ENZYME SUBSTRATE; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE IDENTIFICATION; HUMAN; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SHORT SURVEY; SIDE EFFECT; ANIMAL; GENOME; METABOLISM; REVIEW; SIGNAL TRANSDUCTION;

HYPERICUM; HYPERICUM PERFORATUM;

ANIMALS; GENOME, HUMAN; HUMANS; RECEPTOR CROSS-TALK; RECEPTORS, CYTOPLASMIC AND NUCLEAR; XENOBIOTICS;

EID: 0035851148     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.R100033200     Document Type: Short Survey

References (26)

1. Gonzalez, F. J. (1992) Trends Pharmacol. Sci. 13, 346-352
2. Denison, M. S., and Whitlock, J. P., Jr. (1995) J. Biol. Chem. 270, 18175-18178
3. Waxman, D. J. (1999) Arch. Biochem. Biophys. 369, 11-23
4. Maurel, P. (1996) in Cytochrome P450, Metabolic and Toxicological Aspects (Ioannides, C., ed) pp. 241-270, CRC Press, Inc., Boca Raton, FL
5. Moore, L. B., Goodwin, B., Jones, S. A., Wisely, G. B., Serabjit-Singh, C. J., Willson, T. M., Collins, J. L., and Kliewer, S. A. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 7500-7502
6. Ema, M., Sogawa, K., Watanabe, N., Chujoh, Y., Matsushita, N., Gotoh, O., Funae, Y., and Fujii-Kuriyama, Y. (1992) Biochem. Biophys. Res. Commun. 184, 246-253
7. Barwick, J. L., Quattrochi, L. C., Mills, A. S., Potenza, C., Tukey, R. H., and Guzelian, P. S. (1996) Mol. Pharmacol. 50, 10-16
8. Blumberg, B., Sabbagh, W., Jr., Juguilon, H., Bolado, J., Jr., van Meter, C. M., Ong, E. S., and Evans, R. M. (1998) Genes Dev. 12, 3195-3205
9. Kliewer, S. A., Moore, J. T., Wade, L., Staudinger, J. L., Watson, M. A., Jones, S. A., McKee, D. D., Oliver, B. B., Willson, T. M., Zetterstrom, R. H., Perlmann, T., and Lehmann, J. M. (1998) Cell 92, 73-82
10. Bertilsson, G., Heidrich, J., Svensson, K., Asman, M., Jendeberg, L., Sydow-Backman, M., Ohlsson, R., Postlind, H., Blomquist, P., and Berkenstam, A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 12208-12213
11. Blumberg, B., and Evans, R. M. (1998) Genes Dev. 12, 3149-3155
12. Savas, U., Griffin, K. J., and Johnson, E. F. (1999) Mol. Pharmacol. 56, 851-857
13. Xie, W., Barwick, J. L., Downes, M., Blumberg, B., Simon, C. M., Nelson, M. C., Neuschwander Tetri, B. A., Brunt, E. M., Guzelian, P. S., and Evans, R. M. (2000) Nature 406, 435-439
14. Staudinger, J. L., Goodwin, B., Jones, S. A., Hawkins-Brown, D., MacKenzie, K. I., LaTour, A., Liu, Y., Klaassen, C. D., Brown, K. K., Reinhard, J., Willson, T. M., Koller, B. H., and Kliewer, S. A. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 3369-3374
15. Xie, W., Radominska-Pandya, A., Shi, Y., Simon, C. M., Nelson, M. C., Ong, E. S., Waxman, D. J., and Evans, R. M. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 3375-3380
16. Synold, T. W., Dussault, I., and Forman, B. M. (2001) Nat. Med. 7, 584-590
17. Baes, M., Gulick, T., Choi, H.-S., Martinoli, M. G., Simha, D., and Moore, D. D. (1994) Mol. Cell. Biol. 14, 1544-1552
18. Forman, B. M., Tzameli, I., Choi, H. S., Chen, J., Simha, D., Seol, W., Evans, R. M., and Moore, D. D. (1998) Nature 395, 612-615
19. Honkakoski, P., Zelko, I., Sueyoshi, T., and Negishi, M. (1998) Mol. Cell. Biol. 18, 5652-5658
20. Wei, P., Zhang, J., Egan-Hafley, M., Liang, S., and Moore, D. D. (2000) Nature 407, 920-923
21. Moore, L. B., Parks, D. J., Jones, S. A., Bledsoe, R. K., Consler, T. G., Stimmel, J. B., Goodwin, B., Liddle, C., Blanchard, S. G., Willson, T. M., Collins, J. L., and Kliewer, S. A. (2000) J. Biol. Chem. 275, 15122-15127
22. Xie, W., Barwick, J. L., Simon, C. M., Pierce, A., Safe, S., Blumberg, B., Guzelian, P. S., and Evans, R. M. (2000) Genes Dev. 14, 3014-3023
23. Tzameli, I., Pissios, P., Schuetz, E. G., and Moore, D. D. (2000) Mol. Cell. Biol. 20, 2951-2958
24. Strom, S. C., Pisarov, L. A., Dorko, K., Thompson, M. T., Schuetz, J. D., and Schuetz, E. G. (1996) Methods Enzymol. 272, 388-400
25. Wan, Y. J., An, D., Cai, Y., Repa, J. J., Hung-Po Chen, T., Flores, M., Postic, C., Magnuson, M. A., Chen, J., Chien, K. R., French, S., Mangelsdorf, D. J., and Sucov, H. M. (2000) Mol. Cell. Biol. 20, 4436-4444
26. Howell, S. R., Shirley, M. A., and Ulm, E. H. (1998) Drug Metab. Dispos. 26, 234-239