Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: Studies with cDNA and oligonucleotide expression arrays

Journal of Pharmacology and Experimental Therapeutics

Volumn 299, Issue 3, 2001, Pages 849-857

  Rae, James M ^a,b   Johnson, Michael D ^b   Lippman, Marc E ^b   Flockhart, David A ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; COMPLEMENTARY DNA; CYTOCHROME P450; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C; CYTOCHROME P450 2C18; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; CYTOCHROME P450 3A4; DIMETHYLANILINE MONOOXYGENASE; FLAVIN CONTAINING MONOOXYGENASE 4; FLAVIN CONTAINING MONOOXYGENASE 5; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE P1; MESSENGER RNA; OLIGONUCLEOTIDE; RIFAMPICIN; UDP GLUCURONOSYLTRANSFERASE 1A; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; DRUG EFFECT; DRUG METABOLISM; DRUG SELECTIVITY; ENZYME INDUCTION; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL; NUCLEOTIDE SEQUENCE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIBONUCLEASE PROTECTION ASSAY;

ANTIBIOTICS, ANTITUBERCULAR; CELLS, CULTURED; DNA, COMPLEMENTARY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REPRODUCIBILITY OF RESULTS; RIFAMPIN; RNA, MESSENGER;

EID: 0035201366     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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