Orphan nuclear receptor binding site in the human inducible nitric oxide synthase promoter mediates responsiveness to steroid and xenobiotic ligands

Journal of Cellular Biochemistry

Volumn 85, Issue 1, 2002, Pages 72-82

  Toell, Andrea ^a   Krncke, Klaus Dietrich ^a   Kleinert, Hartmut ^b   Carlberg, Carsten ^c  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

CAR; Gene regulation; Nitric oxide; Orphan nuclear receptors; PXR; Steroids; Xenobiotics

Indexed keywords

CALCITRIOL; CALCITRIOL RECEPTOR; CELL NUCLEUS RECEPTOR; CLOTRIMAZOLE; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450; DNA; LIGAND; LIOTHYRONINE; LIOTHYRONINE RECEPTOR; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PREGNANE X RECEPTOR; RETINOID X RECEPTOR; STEROID; TESTOSTERONE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

APOPTOSIS; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; TRANSCRIPTION REGULATION;

ANDROSTANOLS; BINDING SITES; CLOTRIMAZOLE; CYTOCHROME P-450 ENZYME SYSTEM; DIMERIZATION; GENE EXPRESSION REGULATION; HUMANS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROMOTER REGIONS (GENETICS); RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; RECEPTORS, STEROID; RECEPTORS, THYROID HORMONE; RETINOID X RECEPTORS; STEROIDS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; XENOBIOTICS;

EID: 0036192731     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10104     Document Type: Article

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