Induction of Human CYP2C9 by Rifampicin, Hyperforin, and Phenobarbital Is Mediated by the Pregnane X Receptor

Journal of Pharmacology and Experimental Therapeutics

Volumn 308, Issue 2, 2004, Pages 495-501

  Chen, Yuping ^a   Ferguson, Stephen S ^a   Negishi, Masahiko ^a   Goldstein, Joyce A ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RECEPTOR BLOCKING AGENT; ANDROSTANE DERIVATIVE; ANTICOAGULANT AGENT; ANTICONVULSIVE AGENT; ANTIDIABETIC AGENT; ANTIINFECTIVE AGENT; CELL NUCLEUS RECEPTOR; CELL RECEPTOR; CIS ACTING ELEMENT; CYP2C9 PROTEIN, HUMAN; CYTOCHROME P450 2C9; GLIPIZIDE; HYPERFORIN; HYPERTENSIVE AGENT; LOSARTAN; LUCIFERASE; MESSENGER RNA; NONSTEROID ANTIINFLAMMATORY AGENT; PHENOBARBITAL; PHENYTOIN; PREGNANE X RECEPTOR; RIFAMPICIN; STEROID RECEPTOR; TERPENE; TOLBUTAMIDE; UNSPECIFIC MONOOXYGENASE; WARFARIN;

ARTICLE; BASE PAIRING; BINDING SITE; BIOSYNTHESIS; CELL CULTURE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DRUG BINDING SITE; DRUG EFFECT; DRUG METABOLISM; ENZYME INDUCTION; GENE DELETION; GENE EXPRESSION REGULATION; GENE MUTATION; GENETICS; HUMAN; HUMAN CELL; HYPERICUM PERFORATUM; MUTAGENESIS; PHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; TRANSACTIVATION; TRANSLATION INITIATION;

ANTI-BACTERIAL AGENTS; ARYL HYDROCARBON HYDROXYLASES; BICYCLO COMPOUNDS; BINDING SITES; ENZYME INDUCTION; EXCITATORY AMINO ACID ANTAGONISTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; PHENOBARBITAL; PHLOROGLUCINOL; PROMOTER REGIONS (GENETICS); RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RIFAMPIN; TERPENES; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED;

EID: 1642498178     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.058818     Document Type: Article

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