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Volumn 69, Issue 1, 2006, Pages 99-108

Regulation and binding of pregnane X receptor by nuclear receptor corepressor silencing mediator of retinoid and thyroid hormone receptors (SMRT)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; GLUTATHIONE TRANSFERASE; LIGAND; NUCLEAR RECEPTOR COREPRESSOR; PREGNANE X RECEPTOR; PROTEIN P160; RECEPTOR; RIFAMPICIN; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; STEROID RECEPTOR COACTIVATOR 3; UNCLASSIFIED DRUG;

EID: 30044438390     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.105.013375     Document Type: Article
Times cited : (68)

References (41)
  • 1
    • 0032403230 scopus 로고    scopus 로고
    • The orphan nuclear receptor, COUP-TF II, inhibits myogenesis by post-transcriptional regulation of MyoD function: COUP-TF II directly interacts with p300 and myoD
    • Bailey P, Sartorelli V, Hamamori Y, and Muscat GE (1998) The orphan nuclear receptor, COUP-TF II, inhibits myogenesis by post-transcriptional regulation of MyoD function: COUP-TF II directly interacts with p300 and myoD. Nucleic Acids Res 26:5501-5510.
    • (1998) Nucleic Acids Res , vol.26 , pp. 5501-5510
    • Bailey, P.1    Sartorelli, V.2    Hamamori, Y.3    Muscat, G.E.4
  • 4
    • 0029097233 scopus 로고
    • A transcriptional co-repressor that interacts with nuclear hormone receptors
    • Chen JD and Evans RM (1995) A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature (Lond) 377:454-457.
    • (1995) Nature (Lond) , vol.377 , pp. 454-457
    • Chen, J.D.1    Evans, R.M.2
  • 5
    • 0029794881 scopus 로고    scopus 로고
    • SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers
    • Chen JD, Umesono K, and Evans RM (1996) SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers. Proc Natl Acad Sci USA 93:7567-7571.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7567-7571
    • Chen, J.D.1    Umesono, K.2    Evans, R.M.3
  • 6
    • 0141529776 scopus 로고    scopus 로고
    • Daxx silencing sensitizes cells to multiple apoptotic pathways
    • Chen LY and Chen JD (2003) Daxx silencing sensitizes cells to multiple apoptotic pathways. Mol Cell Biol 23:7108-7121.
    • (2003) Mol Cell Biol , vol.23 , pp. 7108-7121
    • Chen, L.Y.1    Chen, J.D.2
  • 7
    • 0034465602 scopus 로고    scopus 로고
    • The nuclear corepressors recognize distinct nuclear receptor complexes
    • Cohen RN, Putney A, Wondisford FE, and Hollenberg AN (2000) The nuclear corepressors recognize distinct nuclear receptor complexes. Mol Endocrinol 14:900-914.
    • (2000) Mol Endocrinol , vol.14 , pp. 900-914
    • Cohen, R.N.1    Putney, A.2    Wondisford, F.E.3    Hollenberg, A.N.4
  • 8
    • 0029859318 scopus 로고    scopus 로고
    • Two receptor interaction domains in the corepressor, N-CoR/RIP13, are required for an efficient interaction with Rev-erbA alpha and RVR: Physical association is dependent on the E region of the orphan receptors
    • Downes M, Burke LJ, Bailey PJ, and Muscat GE (1996) Two receptor interaction domains in the corepressor, N-CoR/RIP13, are required for an efficient interaction with Rev-erbA alpha and RVR: physical association is dependent on the E region of the orphan receptors. Nucleic Acids Res 24:4379-4386.
    • (1996) Nucleic Acids Res , vol.24 , pp. 4379-4386
    • Downes, M.1    Burke, L.J.2    Bailey, P.J.3    Muscat, G.E.4
  • 12
    • 0032702726 scopus 로고    scopus 로고
    • The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module
    • Goodwin B, Hodgson E, and Liddle C (1999) The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module. Mol Pharmacol 56:1329-1339.
    • (1999) Mol Pharmacol , vol.56 , pp. 1329-1339
    • Goodwin, B.1    Hodgson, E.2    Liddle, C.3
  • 13
    • 0032924934 scopus 로고    scopus 로고
    • Cytochrome P-450 3A4: Regulation and role in drug metabolism
    • Guengerich FP (1999) Cytochrome P-450 3A4: regulation and role in drug metabolism. Annu Rev Pharmacol Toxicol 39:1-17.
    • (1999) Annu Rev Pharmacol Toxicol , vol.39 , pp. 1-17
    • Guengerich, F.P.1
  • 14
    • 0033838465 scopus 로고    scopus 로고
    • The SMRT corepressor is regulated by a MEK-1 kinase pathway: Inhibition of corepressor function is associated with SMRT phosphorylation and nuclear export
    • Hong SH and Privalsky ML (2000) The SMRT corepressor is regulated by a MEK-1 kinase pathway: inhibition of corepressor function is associated with SMRT phosphorylation and nuclear export. Mol Cell Biol 20:6612-6625.
    • (2000) Mol Cell Biol , vol.20 , pp. 6612-6625
    • Hong, S.H.1    Privalsky, M.L.2
  • 16
    • 0033523917 scopus 로고    scopus 로고
    • The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors
    • Hu X and Lazar MA (1999) The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors. Nature (Lond) 402:93-96.
    • (1999) Nature (Lond) , vol.402 , pp. 93-96
    • Hu, X.1    Lazar, M.A.2
  • 17
    • 0038517917 scopus 로고    scopus 로고
    • Liver X receptors interact with corepressors to regulate gene expression
    • Hu X, Li S, Wu J, Xia C, and Lala DS (2003) Liver X receptors interact with corepressors to regulate gene expression. Mol Endocrinol 17:1019-1026.
    • (2003) Mol Endocrinol , vol.17 , pp. 1019-1026
    • Hu, X.1    Li, S.2    Wu, J.3    Xia, C.4    Lala, D.S.5
  • 18
    • 0042592941 scopus 로고    scopus 로고
    • The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor
    • Ishizuka T and Lazar MA (2003) The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor. Mol Cell Biol 23:5122-5131.
    • (2003) Mol Cell Biol , vol.23 , pp. 5122-5131
    • Ishizuka, T.1    Lazar, M.A.2
  • 20
    • 0037169551 scopus 로고    scopus 로고
    • Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor and constitutive androstane receptor
    • Kast HR, Goodwin B, Tarr PT, Jones SA, Anisfeld AM, Stoltz CM, Tontonoz P, Kliewer S, Willson TM, and Edwards PA (2002) Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor and constitutive androstane receptor. J Biol Chem 277:2908-2915.
    • (2002) J Biol Chem , vol.277 , pp. 2908-2915
    • Kast, H.R.1    Goodwin, B.2    Tarr, P.T.3    Jones, S.A.4    Anisfeld, A.M.5    Stoltz, C.M.6    Tontonoz, P.7    Kliewer, S.8    Willson, T.M.9    Edwards, P.A.10
  • 21
    • 0037333974 scopus 로고    scopus 로고
    • Molecular mechanism of nuclear translocation of an orphan nuclear receptor, SXR
    • Kawana K, Ikuta T, Kobayashi Y, Gotoh O, Takeda K, and Kawajiri K (2003) Molecular mechanism of nuclear translocation of an orphan nuclear receptor, SXR. Mol Pharmacol 63:524-531.
    • (2003) Mol Pharmacol , vol.63 , pp. 524-531
    • Kawana, K.1    Ikuta, T.2    Kobayashi, Y.3    Gotoh, O.4    Takeda, K.5    Kawajiri, K.6
  • 23
    • 0032169485 scopus 로고    scopus 로고
    • The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
    • Lehmann JM, McKee DD, Watson MA, Willson TM, Moore JT, and Kliewer SA (1998) The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J Clin Investig 102:1016-1023.
    • (1998) J Clin Investig , vol.102 , pp. 1016-1023
    • Lehmann, J.M.1    McKee, D.D.2    Watson, M.A.3    Willson, T.M.4    Moore, J.T.5    Kliewer, S.A.6
  • 24
    • 0030784510 scopus 로고    scopus 로고
    • Characterization of receptor interaction and transcriptional repression by the corepressor SMRT
    • Li H, Leo C, Schroen DJ, and Chen JD (1997) Characterization of receptor interaction and transcriptional repression by the corepressor SMRT. Mol Endocrinol 11:2025-2037.
    • (1997) Mol Endocrinol , vol.11 , pp. 2025-2037
    • Li, H.1    Leo, C.2    Schroen, D.J.3    Chen, J.D.4
  • 26
    • 0033616676 scopus 로고    scopus 로고
    • SMRTe, a silencing mediator for retinoid and thyroid hormone receptors- extended isoform that is more related to the nuclear receptor corepressor
    • Park EJ, Schroen DJ, Yang M, Li H, Li L, and Chen JD (1999) SMRTe, a silencing mediator for retinoid and thyroid hormone receptors- extended isoform that is more related to the nuclear receptor corepressor. Proc Natl Acad Sci USA 96:3519-3524.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3519-3524
    • Park, E.J.1    Schroen, D.J.2    Yang, M.3    Li, H.4    Li, L.5    Chen, J.D.6
  • 27
    • 0036236065 scopus 로고    scopus 로고
    • Induction of CYP3A expression by dehydroepiandrosterone: Involvement of the pregnane X receptor
    • Ripp SL, Fitzpatrick JL, Peters JM, and Prough RA (2002) Induction of CYP3A expression by dehydroepiandrosterone: involvement of the pregnane X receptor. Drug Metab Dispos 30:570-575.
    • (2002) Drug Metab Dispos , vol.30 , pp. 570-575
    • Ripp, S.L.1    Fitzpatrick, J.L.2    Peters, J.M.3    Prough, R.A.4
  • 30
    • 0032437889 scopus 로고    scopus 로고
    • Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element
    • Schuetz EG, Brimer C, and Schuetz JD (1998) Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element. Mol Pharmacol 54:1113-1117.
    • (1998) Mol Pharmacol , vol.54 , pp. 1113-1117
    • Schuetz, E.G.1    Brimer, C.2    Schuetz, J.D.3
  • 31
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau AK, Barstad D, Loria PM, Cheng L, Kushner PJ, Agard DA, and Greene GL (1998) The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 95:927-937.
    • (1998) Cell , vol.95 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6    Greene, G.L.7
  • 32
    • 0030946201 scopus 로고    scopus 로고
    • Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT)
    • Shibata H, Nawaz Z, Tsai SY, O'Malley BW, and Tsai MJ (1997) Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT). Mol Endocrinol 11:714-724.
    • (1997) Mol Endocrinol , vol.11 , pp. 714-724
    • Shibata, H.1    Nawaz, Z.2    Tsai, S.Y.3    O'Malley, B.W.4    Tsai, M.J.5
  • 33
    • 8344219885 scopus 로고    scopus 로고
    • Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver
    • Squires EJ, Sueyoshi T, and Negishi M (2004) Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver. J Biol Chem 279:49307-49314.
    • (2004) J Biol Chem , vol.279 , pp. 49307-49314
    • Squires, E.J.1    Sueyoshi, T.2    Negishi, M.3
  • 36
    • 0035038919 scopus 로고    scopus 로고
    • The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux
    • Synold TW, Dussault I, and Forman BM (2001) The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat Med 7:584-590.
    • (2001) Nat Med , vol.7 , pp. 584-590
    • Synold, T.W.1    Dussault, I.2    Forman, B.M.3
  • 37
    • 0037031809 scopus 로고    scopus 로고
    • Putative role of the orphan nuclear receptor SXR (steroid and xenobiotic receptor) in the mechanism of CYP3A4 inhibition by xenobiotics
    • Takeshita A, Taguchi M, Koibuchi N, and Ozawa Y (2002) Putative role of the orphan nuclear receptor SXR (steroid and xenobiotic receptor) in the mechanism of CYP3A4 inhibition by xenobiotics. J Biol Chem 277:32453-32458.
    • (2002) J Biol Chem , vol.277 , pp. 32453-32458
    • Takeshita, A.1    Taguchi, M.2    Koibuchi, N.3    Ozawa, Y.4
  • 38
    • 0035968274 scopus 로고    scopus 로고
    • SMRTE inhibits MEF2C transcriptional activation by targeting HDAC4 and 5 to nuclear domains
    • Wu X, Li H, Park EJ, and Chen JD (2001) SMRTE inhibits MEF2C transcriptional activation by targeting HDAC4 and 5 to nuclear domains. J Biol Chem 276:24177-24185.
    • (2001) J Biol Chem , vol.276 , pp. 24177-24185
    • Wu, X.1    Li, H.2    Park, E.J.3    Chen, J.D.4
  • 41
    • 0035076197 scopus 로고    scopus 로고
    • The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver
    • Zelko I, Sueyoshi T, Kawamoto T, Moore R, and Negishi M (2001) The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver. Mol Cell Biol 21:2838-2846.
    • (2001) Mol Cell Biol , vol.21 , pp. 2838-2846
    • Zelko, I.1    Sueyoshi, T.2    Kawamoto, T.3    Moore, R.4    Negishi, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.