-
2
-
-
37649024728
-
Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner
-
Andrabi S., Gjoerup O.V., Kean J.A., Roberts T.M., Schaffhausen B. Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:19011-19016.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 19011-19016
-
-
Andrabi, S.1
Gjoerup, O.V.2
Kean, J.A.3
Roberts, T.M.4
Schaffhausen, B.5
-
3
-
-
80052259754
-
Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2(PP2A)/SET
-
Arnaud L., Chen S., Liu F., Li B., Khatoon S., Grundke-Iqbal I., Iqbal K. Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2(PP2A)/SET. FEBS Letters 2011, 585:2653-2659.
-
(2011)
FEBS Letters
, vol.585
, pp. 2653-2659
-
-
Arnaud, L.1
Chen, S.2
Liu, F.3
Li, B.4
Khatoon, S.5
Grundke-Iqbal, I.6
Iqbal, K.7
-
4
-
-
43049121301
-
A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins
-
Arnold H.K., Sears R.C. A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins. Cancer and Metastasis Reviews 2008, 27:147-158.
-
(2008)
Cancer and Metastasis Reviews
, vol.27
, pp. 147-158
-
-
Arnold, H.K.1
Sears, R.C.2
-
5
-
-
0035208849
-
Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis
-
Atzori C., Ghetti B., Piva R., Srinivasan A.N., Zolo P., Delisle M.B., Mirra S.S., Migheli A. Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis. Journal of Neuropathology and Experimental Neurology 2001, 60:1190-1197.
-
(2001)
Journal of Neuropathology and Experimental Neurology
, vol.60
, pp. 1190-1197
-
-
Atzori, C.1
Ghetti, B.2
Piva, R.3
Srinivasan, A.N.4
Zolo, P.5
Delisle, M.B.6
Mirra, S.S.7
Migheli, A.8
-
6
-
-
0036937699
-
Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
-
Augustinack J.C., Schneider A., Mandelkow E.M., Hyman B.T. Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease. Acta Neuropathologica 2002, 103:26-35.
-
(2002)
Acta Neuropathologica
, vol.103
, pp. 26-35
-
-
Augustinack, J.C.1
Schneider, A.2
Mandelkow, E.M.3
Hyman, B.T.4
-
7
-
-
0034680902
-
Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain
-
Bennecib M., Gong C.X., Grundke-Iqbal I., Iqbal K. Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain. FEBS Letters 2000, 485:87-93.
-
(2000)
FEBS Letters
, vol.485
, pp. 87-93
-
-
Bennecib, M.1
Gong, C.X.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
8
-
-
59649101299
-
Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A
-
Bertoli C., Copetti T., Lam E.W., Demarchi F., Schneider C. Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A. Oncogene 2009, 28:721-733.
-
(2009)
Oncogene
, vol.28
, pp. 721-733
-
-
Bertoli, C.1
Copetti, T.2
Lam, E.W.3
Demarchi, F.4
Schneider, C.5
-
9
-
-
0027338266
-
Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding
-
Biernat J., Gustke N., Drewes G., Mandelkow E.M., Mandelkow E. Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding. Neuron 1993, 11:153-163.
-
(1993)
Neuron
, vol.11
, pp. 153-163
-
-
Biernat, J.1
Gustke, N.2
Drewes, G.3
Mandelkow, E.M.4
Mandelkow, E.5
-
10
-
-
33644532549
-
Towards compendia of negative genetic association studies: an example for Alzheimer disease
-
Blomqvist M.E., Reynolds C., Katzov H., Feuk L., Andreasen N., Bogdanovic N., Blennow K., Brookes A.J., Prince J.A. Towards compendia of negative genetic association studies: an example for Alzheimer disease. Human Genetics 2006, 119:29-37.
-
(2006)
Human Genetics
, vol.119
, pp. 29-37
-
-
Blomqvist, M.E.1
Reynolds, C.2
Katzov, H.3
Feuk, L.4
Andreasen, N.5
Bogdanovic, N.6
Blennow, K.7
Brookes, A.J.8
Prince, J.A.9
-
11
-
-
70349638299
-
Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies
-
Brunden K.R., Trojanowski J.Q., Lee V.M. Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies. Nature Reviews Drug Discovery 2009, 8:783-793.
-
(2009)
Nature Reviews Drug Discovery
, vol.8
, pp. 783-793
-
-
Brunden, K.R.1
Trojanowski, J.Q.2
Lee, V.M.3
-
12
-
-
0033551070
-
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
-
Cantley L.C., Neel B.G. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proceedings of the National Academy of Sciences of the United States of America 1999, 96:4240-4245.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, pp. 4240-4245
-
-
Cantley, L.C.1
Neel, B.G.2
-
13
-
-
60349084974
-
Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway
-
Chen L., Liu L., Yin J., Luo Y., Huang S. Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway. International Journal of Biochemistry and Cell Biology 2009, 41:1284-1295.
-
(2009)
International Journal of Biochemistry and Cell Biology
, vol.41
, pp. 1284-1295
-
-
Chen, L.1
Liu, L.2
Yin, J.3
Luo, Y.4
Huang, S.5
-
14
-
-
83855162924
-
Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling
-
Chen L.M., Xiong Y.S., Kong F.L., Qu M., Wang Q., Chen X.Q., Wang J.Z., Zhu L.Q. Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling. Journal of Neurochemistry 2012, 120:157-164.
-
(2012)
Journal of Neurochemistry
, vol.120
, pp. 157-164
-
-
Chen, L.M.1
Xiong, Y.S.2
Kong, F.L.3
Qu, M.4
Wang, Q.5
Chen, X.Q.6
Wang, J.Z.7
Zhu, L.Q.8
-
15
-
-
0031015069
-
Activation of protein phosphatase 5 by limited proteolysis or the binding of polyunsaturated fatty acids to the TPR domain
-
Chen M.X., Cohen P.T. Activation of protein phosphatase 5 by limited proteolysis or the binding of polyunsaturated fatty acids to the TPR domain. FEBS Letters 1997, 400:136-140.
-
(1997)
FEBS Letters
, vol.400
, pp. 136-140
-
-
Chen, M.X.1
Cohen, P.T.2
-
16
-
-
44849144122
-
I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A
-
Chen S., Li B., Grundke-Iqbal I., Iqbal K. I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A. Journal of Biological Chemistry 2008, 283:10513-10521.
-
(2008)
Journal of Biological Chemistry
, vol.283
, pp. 10513-10521
-
-
Chen, S.1
Li, B.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
17
-
-
0043193866
-
Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis
-
Chiang C.W., Kanies C., Kim K.W., Fang W.B., Parkhurst C., Xie M., Henry T., Yang E. Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis. Molecular and Cellular Biology 2003, 23:6350-6362.
-
(2003)
Molecular and Cellular Biology
, vol.23
, pp. 6350-6362
-
-
Chiang, C.W.1
Kanies, C.2
Kim, K.W.3
Fang, W.B.4
Parkhurst, C.5
Xie, M.6
Henry, T.7
Yang, E.8
-
18
-
-
0033758105
-
Microtubule-affinity regulating kinase MARK) is tightly associated with neurofibrillary tangles in Alzheimer brain: a fluorescence resonance energy transfer study
-
Chin J.Y., Knowles R.B., Schneider A., Drewes G., Mandelkow E.M., Hyman B.T. Microtubule-affinity regulating kinase MARK) is tightly associated with neurofibrillary tangles in Alzheimer brain: a fluorescence resonance energy transfer study. Journal of Neuropathology and Experimental Neurology 2000, 59:966-971.
-
(2000)
Journal of Neuropathology and Experimental Neurology
, vol.59
, pp. 966-971
-
-
Chin, J.Y.1
Knowles, R.B.2
Schneider, A.3
Drewes, G.4
Mandelkow, E.M.5
Hyman, B.T.6
-
19
-
-
0035234311
-
Protein phosphatase 5 in signal transduction
-
Chinkers M. Protein phosphatase 5 in signal transduction. Trends in Endocrinology & Metabolism 2001, 12:28-32.
-
(2001)
Trends in Endocrinology & Metabolism
, vol.12
, pp. 28-32
-
-
Chinkers, M.1
-
20
-
-
33846118688
-
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme
-
Cho U.S., Xu W. Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme. Nature 2007, 445:53-57.
-
(2007)
Nature
, vol.445
, pp. 53-57
-
-
Cho, U.S.1
Xu, W.2
-
21
-
-
33745370049
-
Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine
-
Chohan M.O., Khatoon S., Iqbal I.G., Iqbal K. Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine. FEBS Letters 2006, 580:3973-3979.
-
(2006)
FEBS Letters
, vol.580
, pp. 3973-3979
-
-
Chohan, M.O.1
Khatoon, S.2
Iqbal, I.G.3
Iqbal, K.4
-
22
-
-
70349570600
-
Aberrant phosphorylation in the pathogenesis of Alzheimer's disease
-
Chung S.H. Aberrant phosphorylation in the pathogenesis of Alzheimer's disease. BMB Report 2009, 42:467-474.
-
(2009)
BMB Report
, vol.42
, pp. 467-474
-
-
Chung, S.H.1
-
23
-
-
13844256246
-
Molecular recognition via coupled folding and binding in a TPR domain
-
Cliff M.J., Williams M.A., Brooke-Smith J., Barford D., Ladbury J.E. Molecular recognition via coupled folding and binding in a TPR domain. Journal of Molecular Biology 2005, 346:717-732.
-
(2005)
Journal of Molecular Biology
, vol.346
, pp. 717-732
-
-
Cliff, M.J.1
Williams, M.A.2
Brooke-Smith, J.3
Barford, D.4
Ladbury, J.E.5
-
24
-
-
24644499539
-
Expression of calcipressin 1, an inhibitor of the phosphatase calcineurin, is altered with aging and Alzheimer's disease
-
Cook C.N., Hejna M.J., Magnuson D.J., Lee J.M. Expression of calcipressin 1, an inhibitor of the phosphatase calcineurin, is altered with aging and Alzheimer's disease. Journal of Alzheimer's Disease 2005, 8:63-73.
-
(2005)
Journal of Alzheimer's Disease
, vol.8
, pp. 63-73
-
-
Cook, C.N.1
Hejna, M.J.2
Magnuson, D.J.3
Lee, J.M.4
-
25
-
-
81355127353
-
Neuroglial alterations in rats submitted to the okadaic acid-induced model of dementia
-
Costa A.P., Tramontina A.C., Biasibetti R., Batassini C., Lopes M.W., Wartchow K.M., Bernardi C., Tortorelli L.S., Leal R.B., Goncalves C.A. Neuroglial alterations in rats submitted to the okadaic acid-induced model of dementia. Behavioural Brain Research 2012, 226:420-427.
-
(2012)
Behavioural Brain Research
, vol.226
, pp. 420-427
-
-
Costa, A.P.1
Tramontina, A.C.2
Biasibetti, R.3
Batassini, C.4
Lopes, M.W.5
Wartchow, K.M.6
Bernardi, C.7
Tortorelli, L.S.8
Leal, R.B.9
Goncalves, C.A.10
-
26
-
-
0029328289
-
Greengard P Inhibition of protein phosphatase 1 stimulates secretion of Alzheimer amyloid precursor protein
-
da Cruz e Silva E.F., da Cruz e Silva O.A., Zaia C.T. Greengard P Inhibition of protein phosphatase 1 stimulates secretion of Alzheimer amyloid precursor protein. Molecular Medicine 1995, 1:535-541.
-
(1995)
Molecular Medicine
, vol.1
, pp. 535-541
-
-
da Cruz e Silva, E.F.1
da Cruz e Silva, O.A.2
Zaia, C.T.3
-
27
-
-
60249095382
-
The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission
-
Dagda R.K., Merrill R.A., Cribbs J.T., Chen Y., Hell J.W., Usachev Y.M., Strack S. The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission. Journal of Biological Chemistry 2008, 283:36241-36248.
-
(2008)
Journal of Biological Chemistry
, vol.283
, pp. 36241-36248
-
-
Dagda, R.K.1
Merrill, R.A.2
Cribbs, J.T.3
Chen, Y.4
Hell, J.W.5
Usachev, Y.M.6
Strack, S.7
-
28
-
-
0043092070
-
A developmentally regulated, neuron-specific splice variant of the variable subunit Bbeta targets protein phosphatase 2A to mitochondria and modulates apoptosis
-
Dagda R.K., Zaucha J.A., Wadzinski B.E., Strack S. A developmentally regulated, neuron-specific splice variant of the variable subunit Bbeta targets protein phosphatase 2A to mitochondria and modulates apoptosis. Journal of Biological Chemistry 2003, 278:24976-24985.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 24976-24985
-
-
Dagda, R.K.1
Zaucha, J.A.2
Wadzinski, B.E.3
Strack, S.4
-
29
-
-
0033554835
-
Purification of porcine brain protein phosphatase 2A leucine carboxyl methyltransferase and cloning of the human homologue
-
De Baere I., Derua R., Janssens V., Van Hoof C., Waelkens E., Merlevede W., Goris J. Purification of porcine brain protein phosphatase 2A leucine carboxyl methyltransferase and cloning of the human homologue. Biochemistry 1999, 38:16539-16547.
-
(1999)
Biochemistry
, vol.38
, pp. 16539-16547
-
-
De Baere, I.1
Derua, R.2
Janssens, V.3
Van Hoof, C.4
Waelkens, E.5
Merlevede, W.6
Goris, J.7
-
30
-
-
22244475384
-
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase
-
Derkinderen P., Scales T.M., Hanger D.P., Leung K.Y., Byers H.L., Ward M.A., Lenz C., Price C., Bird I.N., Perera T., Kellie S., Williamson R., Noble W., Van Etten R.A., Leroy K., Brion J.P., Reynolds C.H., Anderton B.H. Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase. Journal of Neuroscience 2005, 25:6584-6593.
-
(2005)
Journal of Neuroscience
, vol.25
, pp. 6584-6593
-
-
Derkinderen, P.1
Scales, T.M.2
Hanger, D.P.3
Leung, K.Y.4
Byers, H.L.5
Ward, M.A.6
Lenz, C.7
Price, C.8
Bird, I.N.9
Perera, T.10
Kellie, S.11
Williamson, R.12
Noble, W.13
Van Etten, R.A.14
Leroy, K.15
Brion, J.P.16
Reynolds, C.H.17
Anderton, B.H.18
-
32
-
-
33646246733
-
HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites
-
Dickey C.A., Dunmore J., Lu B., Wang J.W., Lee W.C., Kamal A., Burrows F., Eckman C., Hutton M., Petrucelli L. HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites. FASEB Journal 2006, 20:753-755.
-
(2006)
FASEB Journal
, vol.20
, pp. 753-755
-
-
Dickey, C.A.1
Dunmore, J.2
Lu, B.3
Wang, J.W.4
Lee, W.C.5
Kamal, A.6
Burrows, F.7
Eckman, C.8
Hutton, M.9
Petrucelli, L.10
-
33
-
-
33847369469
-
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
-
Dickey C.A., Kamal A., Lundgren K., Klosak N., Bailey R.M., Dunmore J., Ash P., Shoraka S., Zlatkovic J., Eckman C.B., Patterson C., Dickson D.W., Nahman N.S., Hutton M., Burrows F., Petrucelli L. The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins. Journal of Clinical Investigation 2007, 117:648-658.
-
(2007)
Journal of Clinical Investigation
, vol.117
, pp. 648-658
-
-
Dickey, C.A.1
Kamal, A.2
Lundgren, K.3
Klosak, N.4
Bailey, R.M.5
Dunmore, J.6
Ash, P.7
Shoraka, S.8
Zlatkovic, J.9
Eckman, C.B.10
Patterson, C.11
Dickson, D.W.12
Nahman, N.S.13
Hutton, M.14
Burrows, F.15
Petrucelli, L.16
-
34
-
-
79952155653
-
The Discodermia calyx Toxin Calyculin A Enhances Cyclin D1 Phosphorylation and Degradation, and Arrests Cell Cycle Progression in Human Breast Cancer Cells
-
Edelson J.R., Brautigan D.L. The Discodermia calyx Toxin Calyculin A Enhances Cyclin D1 Phosphorylation and Degradation, and Arrests Cell Cycle Progression in Human Breast Cancer Cells. Toxins (Basel) 2012, 3:105-119.
-
(2012)
Toxins (Basel)
, vol.3
, pp. 105-119
-
-
Edelson, J.R.1
Brautigan, D.L.2
-
35
-
-
33646258512
-
RCAN1 (DSCR1 or Adapt78) stimulates expression of GSK-3beta
-
Ermak G., Harris C.D., Battocchio D., Davies K.J. RCAN1 (DSCR1 or Adapt78) stimulates expression of GSK-3beta. FASEB Journal 2006, 273:2100-2109.
-
(2006)
FASEB Journal
, vol.273
, pp. 2100-2109
-
-
Ermak, G.1
Harris, C.D.2
Battocchio, D.3
Davies, K.J.4
-
36
-
-
0036944509
-
Anti-tau phospho-specific Ser262 antibody recognizes a variety of abnormal hyper-phosphorylated tau deposits in tauopathies including Pick bodies and argyrophilic grains
-
Ferrer I., Barrachina M., Puig B. Anti-tau phospho-specific Ser262 antibody recognizes a variety of abnormal hyper-phosphorylated tau deposits in tauopathies including Pick bodies and argyrophilic grains. Acta Neuropathologica 2002, 104:658-664.
-
(2002)
Acta Neuropathologica
, vol.104
, pp. 658-664
-
-
Ferrer, I.1
Barrachina, M.2
Puig, B.3
-
37
-
-
0035094403
-
Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration
-
Ferrer I., Blanco R., Carmona M., Ribera R., Goutan E., Puig B., Rey M.J., Cardozo A., Vinals F., Ribalta T. Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. Brain Pathology 2001, 11:144-158.
-
(2001)
Brain Pathology
, vol.11
, pp. 144-158
-
-
Ferrer, I.1
Blanco, R.2
Carmona, M.3
Ribera, R.4
Goutan, E.5
Puig, B.6
Rey, M.J.7
Cardozo, A.8
Vinals, F.9
Ribalta, T.10
-
38
-
-
0028813436
-
The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells
-
Fruman D.A., Bierer B.E., Benes J.E., Burakoff S.J., Austen K.F., Katz H.R. The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells. Journal of Immunology 1995, 154:1846-1851.
-
(1995)
Journal of Immunology
, vol.154
, pp. 1846-1851
-
-
Fruman, D.A.1
Bierer, B.E.2
Benes, J.E.3
Burakoff, S.J.4
Austen, K.F.5
Katz, H.R.6
-
39
-
-
0026503434
-
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A
-
Fruman D.A., Klee C.B., Bierer B.E., Burakoff S.J. Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proceedings of the National Academy of Sciences of the United States of America 1992, 89:3686-3690.
-
(1992)
Proceedings of the National Academy of Sciences of the United States of America
, vol.89
, pp. 3686-3690
-
-
Fruman, D.A.1
Klee, C.B.2
Bierer, B.E.3
Burakoff, S.J.4
-
40
-
-
0029868933
-
Inhibition of protein serine/threonine phosphatases by fumonisin B1, a mycotoxin
-
Fukuda H., Shima H., Vesonder R.F., Tokuda H., Nishino H., Katoh S., Tamura S., Sugimura T., Nagao M. Inhibition of protein serine/threonine phosphatases by fumonisin B1, a mycotoxin. Biochemical and Biophysical Research Communications 1996, 220:160-165.
-
(1996)
Biochemical and Biophysical Research Communications
, vol.220
, pp. 160-165
-
-
Fukuda, H.1
Shima, H.2
Vesonder, R.F.3
Tokuda, H.4
Nishino, H.5
Katoh, S.6
Tamura, S.7
Sugimura, T.8
Nagao, M.9
-
41
-
-
0032870947
-
A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease
-
Ghoshal N., Smiley J.F., DeMaggio A.J., Hoekstra M.F., Cochran E.J., Binder L.I., Kuret J. A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease. American Journal of Pathology 1999, 155:1163-1172.
-
(1999)
American Journal of Pathology
, vol.155
, pp. 1163-1172
-
-
Ghoshal, N.1
Smiley, J.F.2
DeMaggio, A.J.3
Hoekstra, M.F.4
Cochran, E.J.5
Binder, L.I.6
Kuret, J.7
-
42
-
-
55249086251
-
Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease
-
Gong C.X., Iqbal K. Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease. Current Medicinal Chemistry 2008, 15:2321-2328.
-
(2008)
Current Medicinal Chemistry
, vol.15
, pp. 2321-2328
-
-
Gong, C.X.1
Iqbal, K.2
-
43
-
-
0345825934
-
Dephosphorylation of microtubule-associated protein tau by protein phosphatase 5
-
Gong C.X., Liu F., Wu G., Rossie S., Wegiel J., Li L., Grundke-Iqbal I., Iqbal K. Dephosphorylation of microtubule-associated protein tau by protein phosphatase 5. Journal of Neurochemistry 2004, 88:298-310.
-
(2004)
Journal of Neurochemistry
, vol.88
, pp. 298-310
-
-
Gong, C.X.1
Liu, F.2
Wu, G.3
Rossie, S.4
Wegiel, J.5
Li, L.6
Grundke-Iqbal, I.7
Iqbal, K.8
-
44
-
-
0029113874
-
Phosphatase activity toward abnormally phosphorylated tau: decrease in Alzheimer disease brain
-
Gong C.X., Shaikh S., Wang J.Z., Zaidi T., Grundke-Iqbal I., Iqbal K. Phosphatase activity toward abnormally phosphorylated tau: decrease in Alzheimer disease brain. Journal of Neurochemistry 1995, 65:732-738.
-
(1995)
Journal of Neurochemistry
, vol.65
, pp. 732-738
-
-
Gong, C.X.1
Shaikh, S.2
Wang, J.Z.3
Zaidi, T.4
Grundke-Iqbal, I.5
Iqbal, K.6
-
45
-
-
0027214404
-
Phosphoprotein phosphatase activities in Alzheimer disease brain
-
Gong C.X., Singh T.J., Grundke-Iqbal I., Iqbal K. Phosphoprotein phosphatase activities in Alzheimer disease brain. Journal of Neurochemistry 1993, 61:921-927.
-
(1993)
Journal of Neurochemistry
, vol.61
, pp. 921-927
-
-
Gong, C.X.1
Singh, T.J.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
46
-
-
0028049937
-
Casein kinase II preferentially phosphorylates human tau isoforms containing an amino-terminal insert, Identification of threonine 39 as the primary phosphate acceptor
-
Greenwood J.A., Scott C.W., Spreen R.C., Caputo C.B., Johnson G.V. Casein kinase II preferentially phosphorylates human tau isoforms containing an amino-terminal insert, Identification of threonine 39 as the primary phosphate acceptor. Journal of Biological Chemistry 1994, 269:4373-4380.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 4373-4380
-
-
Greenwood, J.A.1
Scott, C.W.2
Spreen, R.C.3
Caputo, C.B.4
Johnson, G.V.5
-
47
-
-
16244391770
-
Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology
-
Griffin R.J., Moloney A., Kelliher M., Johnston J.A., Ravid R., Dockery P., O'Connor R., O'Neill C. Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology. Journal of Neurochemistry 2005, 93:105-117.
-
(2005)
Journal of Neurochemistry
, vol.93
, pp. 105-117
-
-
Griffin, R.J.1
Moloney, A.2
Kelliher, M.3
Johnston, J.A.4
Ravid, R.5
Dockery, P.6
O'Connor, R.7
O'Neill, C.8
-
48
-
-
0035896366
-
Protein kinase B (PKB/Akt)-a key regulator of glucose transport?
-
Hajduch E., Litherland G.J., Hundal H.S. Protein kinase B (PKB/Akt)-a key regulator of glucose transport?. FEBS Letters 2001, 492:199-203.
-
(2001)
FEBS Letters
, vol.492
, pp. 199-203
-
-
Hajduch, E.1
Litherland, G.J.2
Hundal, H.S.3
-
49
-
-
33646401564
-
Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease
-
Hamilton G., Samedi F., Knight J., Archer N., Foy C., Walter S., Turic D., Jehu L., Moore P., Hollingworth P., O'Donovan M.C., Williams J., Owen M.J., Lovestone S., Powell J.F. Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease. Neuroscience Letters 2006, 401:77-80.
-
(2006)
Neuroscience Letters
, vol.401
, pp. 77-80
-
-
Hamilton, G.1
Samedi, F.2
Knight, J.3
Archer, N.4
Foy, C.5
Walter, S.6
Turic, D.7
Jehu, L.8
Moore, P.9
Hollingworth, P.10
O'Donovan, M.C.11
Williams, J.12
Owen, M.J.13
Lovestone, S.14
Powell, J.F.15
-
50
-
-
61849088424
-
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
-
Hanger D.P., Anderton B.H., Noble W. Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. Trends in Molecular Medicine 2009, 15:112-119.
-
(2009)
Trends in Molecular Medicine
, vol.15
, pp. 112-119
-
-
Hanger, D.P.1
Anderton, B.H.2
Noble, W.3
-
51
-
-
34548191034
-
Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis
-
Hanger D.P., Byers H.L., Wray S., Leung K.Y., Saxton M.J., Seereeram A., Reynolds C.H., Ward M.A., Anderton B.H. Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis. Journal of Biological Chemistry 2007, 282:23645-23654.
-
(2007)
Journal of Biological Chemistry
, vol.282
, pp. 23645-23654
-
-
Hanger, D.P.1
Byers, H.L.2
Wray, S.3
Leung, K.Y.4
Saxton, M.J.5
Seereeram, A.6
Reynolds, C.H.7
Ward, M.A.8
Anderton, B.H.9
-
52
-
-
0032563347
-
Purification of protein phosphatase 4 catalytic subunit: inhibition by the antitumour drug fostriecin and other tumour suppressors and promoters
-
Hastie C.J., Cohen P.T. Purification of protein phosphatase 4 catalytic subunit: inhibition by the antitumour drug fostriecin and other tumour suppressors and promoters. FEBS Letters 1998, 431:357-361.
-
(1998)
FEBS Letters
, vol.431
, pp. 357-361
-
-
Hastie, C.J.1
Cohen, P.T.2
-
53
-
-
84984567283
-
Diphenyl ditelluride induces hypophosphorylation of intermediate filaments through modulation of DARPP-32-dependent pathways in cerebral cortex of young rats
-
Heimfarth L., Loureiro S.O., Reis K.P., de Lima B.O., Zamboni F., Lacerda S., Soska A.K., Wild L., da Rocha J.B., Pessoa-Pureur R. Diphenyl ditelluride induces hypophosphorylation of intermediate filaments through modulation of DARPP-32-dependent pathways in cerebral cortex of young rats. Archives of Toxicology 2012, 86:217-230.
-
(2012)
Archives of Toxicology
, vol.86
, pp. 217-230
-
-
Heimfarth, L.1
Loureiro, S.O.2
Reis, K.P.3
de Lima, B.O.4
Zamboni, F.5
Lacerda, S.6
Soska, A.K.7
Wild, L.8
da Rocha, J.B.9
Pessoa-Pureur, R.10
-
54
-
-
0021162349
-
DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1
-
Hemmings H.C., Greengard P., Tung H.Y., Cohen P. DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1. Nature 1984, 310:503-505.
-
(1984)
Nature
, vol.310
, pp. 503-505
-
-
Hemmings, H.C.1
Greengard, P.2
Tung, H.Y.3
Cohen, P.4
-
55
-
-
0033043939
-
P38 kinase is activated in the Alzheimer's disease brain
-
Hensley K., Floyd R.A., Zheng N.Y., Nael R., Robinson K.A., Nguyen X., Pye Q.N., Stewart C.A., Geddes J., Markesbery W.R., Patel E., Johnson G.V., Bing G. p38 kinase is activated in the Alzheimer's disease brain. Journal of Neurochemistry 1999, 72:2053-2058.
-
(1999)
Journal of Neurochemistry
, vol.72
, pp. 2053-2058
-
-
Hensley, K.1
Floyd, R.A.2
Zheng, N.Y.3
Nael, R.4
Robinson, K.A.5
Nguyen, X.6
Pye, Q.N.7
Stewart, C.A.8
Geddes, J.9
Markesbery, W.R.10
Patel, E.11
Johnson, G.V.12
Bing, G.13
-
56
-
-
77952546195
-
Avila J (GSK3: a possible link between beta amyloid peptide and tau protein
-
Hernandez F., Gomez de Barreda E., Fuster-Matanzo A., Lucas J.J. Avila J (GSK3: a possible link between beta amyloid peptide and tau protein. Experimental Neurology 2010, 223:322-325.
-
(2010)
Experimental Neurology
, vol.223
, pp. 322-325
-
-
Hernandez, F.1
Gomez de Barreda, E.2
Fuster-Matanzo, A.3
Lucas, J.J.4
-
57
-
-
0034163509
-
Protein phosphatase 2A is associated in an inactive state with microtubules through 2A1-specific interaction with tubulin
-
Hiraga A., Tamura S. Protein phosphatase 2A is associated in an inactive state with microtubules through 2A1-specific interaction with tubulin. Biochemical Journal 2000, 346(Pt 2):433-439.
-
(2000)
Biochemical Journal
, vol.346
, Issue.PART. 2
, pp. 433-439
-
-
Hiraga, A.1
Tamura, S.2
-
58
-
-
21044448540
-
Mechanisms of cell signaling and inflammation in Alzheimer's disease
-
Ho G.J., Drego R., Hakimian E., Masliah E. Mechanisms of cell signaling and inflammation in Alzheimer's disease. Current Drug Targets - Inflammation & Allergy 2005, 4:247-256.
-
(2005)
Current Drug Targets - Inflammation & Allergy
, vol.4
, pp. 247-256
-
-
Ho, G.J.1
Drego, R.2
Hakimian, E.3
Masliah, E.4
-
59
-
-
84863242250
-
Endoplasmic reticulum stress induces tau pathology and forms a vicious cycle: implication in Alzheimer's disease pathogenesis
-
Ho Y.S., Yang X., Lau J.C., Hung C.H., Wuwongse S., Zhang Q., Wang J., Baum L., So K.F., Chang R.C. Endoplasmic reticulum stress induces tau pathology and forms a vicious cycle: implication in Alzheimer's disease pathogenesis. Journal of Alzheimer's Disease 2012.
-
(2012)
Journal of Alzheimer's Disease
-
-
Ho, Y.S.1
Yang, X.2
Lau, J.C.3
Hung, C.H.4
Wuwongse, S.5
Zhang, Q.6
Wang, J.7
Baum, L.8
So, K.F.9
Chang, R.C.10
-
60
-
-
0027217027
-
Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A
-
Honkanen R.E. Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A. FEBS Letters 1993, 330:283-286.
-
(1993)
FEBS Letters
, vol.330
, pp. 283-286
-
-
Honkanen, R.E.1
-
61
-
-
0026015352
-
Cyanobacterial nodularin is a potent inhibitor of type 1 and type 2A protein phosphatases
-
Honkanen R.E., Dukelow M., Zwiller J., Moore R.E., Khatra B.S., Boynton A.L. Cyanobacterial nodularin is a potent inhibitor of type 1 and type 2A protein phosphatases. Molecular Pharmacology 1991, 40:577-583.
-
(1991)
Molecular Pharmacology
, vol.40
, pp. 577-583
-
-
Honkanen, R.E.1
Dukelow, M.2
Zwiller, J.3
Moore, R.E.4
Khatra, B.S.5
Boynton, A.L.6
-
62
-
-
0036032778
-
Regulators of serine/threonine protein phosphatases at the dawn of a clinical era?
-
Honkanen R.E., Golden T. Regulators of serine/threonine protein phosphatases at the dawn of a clinical era?. Current Medicinal Chemistry 2002, 9:2055-2075.
-
(2002)
Current Medicinal Chemistry
, vol.9
, pp. 2055-2075
-
-
Honkanen, R.E.1
Golden, T.2
-
63
-
-
0025201229
-
Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases
-
Honkanen R.E., Zwiller J., Moore R.E., Daily S.L., Khatra B.S., Dukelow M., Boynton A.L. Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases. Journal of Biological Chemistry 1990, 265:19401-19404.
-
(1990)
Journal of Biological Chemistry
, vol.265
, pp. 19401-19404
-
-
Honkanen, R.E.1
Zwiller, J.2
Moore, R.E.3
Daily, S.L.4
Khatra, B.S.5
Dukelow, M.6
Boynton, A.L.7
-
65
-
-
67349142329
-
Alonso Adel C, Grundke-Iqbal I Mechanisms of tau-induced neurodegeneration
-
Iqbal K., Liu F., Gong C.X. Alonso Adel C, Grundke-Iqbal I Mechanisms of tau-induced neurodegeneration. Acta Neuropathologica 2009, 118:53-69.
-
(2009)
Acta Neuropathologica
, vol.118
, pp. 53-69
-
-
Iqbal, K.1
Liu, F.2
Gong, C.X.3
-
66
-
-
0034709459
-
Dual effects of PKNalpha and protein kinase C on phosphorylation of tau protein by glycogen synthase kinase-3beta
-
Isagawa T., Mukai H., Oishi K., Taniguchi T., Hasegawa H., Kawamata T., Tanaka C., Ono Y. Dual effects of PKNalpha and protein kinase C on phosphorylation of tau protein by glycogen synthase kinase-3beta. Biochemical and Biophysical Research Communications 2000, 273:209-212.
-
(2000)
Biochemical and Biophysical Research Communications
, vol.273
, pp. 209-212
-
-
Isagawa, T.1
Mukai, H.2
Oishi, K.3
Taniguchi, T.4
Hasegawa, H.5
Kawamata, T.6
Tanaka, C.7
Ono, Y.8
-
67
-
-
0024517280
-
Calyculin A and okadaic acid: inhibitors of protein phosphatase activity
-
Ishihara H., Martin B.L., Brautigan D.L., Karaki H., Ozaki H., Kato Y., Fusetani N., Watabe S., Hashimoto K., Uemura D., et al. Calyculin A and okadaic acid: inhibitors of protein phosphatase activity. Biochemical and Biophysical Research Communications 1989, 159:871-877.
-
(1989)
Biochemical and Biophysical Research Communications
, vol.159
, pp. 871-877
-
-
Ishihara, H.1
Martin, B.L.2
Brautigan, D.L.3
Karaki, H.4
Ozaki, H.5
Kato, Y.6
Fusetani, N.7
Watabe, S.8
Hashimoto, K.9
Uemura, D.10
-
68
-
-
0035252894
-
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
-
Janssens V., Goris J. Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochemical Journal 2001, 353:417-439.
-
(2001)
Biochemical Journal
, vol.353
, pp. 417-439
-
-
Janssens, V.1
Goris, J.2
-
70
-
-
39949083195
-
PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail)
-
Janssens V., Longin S., Goris J. PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail). Trends in Biochemical Sciences 2008, 33:113-121.
-
(2008)
Trends in Biochemical Sciences
, vol.33
, pp. 113-121
-
-
Janssens, V.1
Longin, S.2
Goris, J.3
-
71
-
-
0033198043
-
CAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease
-
Jicha G.A., Weaver C., Lane E., Vianna C., Kress Y., Rockwood J., Davies P. cAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease. Journal of Neuroscience 1999, 19:7486-7494.
-
(1999)
Journal of Neuroscience
, vol.19
, pp. 7486-7494
-
-
Jicha, G.A.1
Weaver, C.2
Lane, E.3
Vianna, C.4
Kress, Y.5
Rockwood, J.6
Davies, P.7
-
72
-
-
84856561031
-
Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models
-
Jones N.C., Nguyen T., Corcoran N.M., Velakoulis D., Chen T., Grundy R., O'Brien T.J., Hovens C.M. Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models. Neurobiology of Disease 2012.
-
(2012)
Neurobiology of Disease
-
-
Jones, N.C.1
Nguyen, T.2
Corcoran, N.M.3
Velakoulis, D.4
Chen, T.5
Grundy, R.6
O'Brien, T.J.7
Hovens, C.M.8
-
73
-
-
0027471688
-
Cohen PT (Localization of the genes encoding the catalytic subunits of protein phosphatase 2A to human chromosome bands 5q23→q31 and 8p12→p11.2, respectively
-
Jones T.A., Barker H.M., da Cruz e Silva E.F., Mayer-Jaekel R.E., Hemmings B.A., Spurr N.K., Sheer D. Cohen PT (Localization of the genes encoding the catalytic subunits of protein phosphatase 2A to human chromosome bands 5q23→q31 and 8p12→p11.2, respectively. Cytogenetics and Cell Genetics 1993, 63:35-41.
-
(1993)
Cytogenetics and Cell Genetics
, vol.63
, pp. 35-41
-
-
Jones, T.A.1
Barker, H.M.2
da Cruz e Silva, E.F.3
Mayer-Jaekel, R.E.4
Hemmings, B.A.5
Spurr, N.K.6
Sheer, D.7
-
74
-
-
0032530750
-
A protein kinase, PKN, accumulates in Alzheimer neurofibrillary tangles and associated endoplasmic reticulum-derived vesicles and phosphorylates tau protein
-
Kawamata T., Taniguchi T., Mukai H., Kitagawa M., Hashimoto T., Maeda K., Ono Y., Tanaka C. A protein kinase, PKN, accumulates in Alzheimer neurofibrillary tangles and associated endoplasmic reticulum-derived vesicles and phosphorylates tau protein. Journal of Neuroscience 1998, 18:7402-7410.
-
(1998)
Journal of Neuroscience
, vol.18
, pp. 7402-7410
-
-
Kawamata, T.1
Taniguchi, T.2
Mukai, H.3
Kitagawa, M.4
Hashimoto, T.5
Maeda, K.6
Ono, Y.7
Tanaka, C.8
-
75
-
-
33646751445
-
PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3
-
Kerr F., Rickle A., Nayeem N., Brandner S., Cowburn R.F., Lovestone S. PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3. FEBS Letters 2006, 580:3121-3128.
-
(2006)
FEBS Letters
, vol.580
, pp. 3121-3128
-
-
Kerr, F.1
Rickle, A.2
Nayeem, N.3
Brandner, S.4
Cowburn, R.F.5
Lovestone, S.6
-
76
-
-
37049048544
-
Paired helical filaments in electron microscopy of Alzheimer's disease
-
Kidd M. Paired helical filaments in electron microscopy of Alzheimer's disease. Nature 1963, 197:192-193.
-
(1963)
Nature
, vol.197
, pp. 192-193
-
-
Kidd, M.1
-
77
-
-
33846533244
-
The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease
-
Kimura R., Kamino K., Yamamoto M., Nuripa A., Kida T., Kazui H., Hashimoto R., Tanaka T., Kudo T., Yamagata H., Tabara Y., Miki T., Akatsu H., Kosaka K., Funakoshi E., Nishitomi K., Sakaguchi G., Kato A., Hattori H., Uema T., Takeda M. The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease. Human Molecular Genetics 2007, 16:15-23.
-
(2007)
Human Molecular Genetics
, vol.16
, pp. 15-23
-
-
Kimura, R.1
Kamino, K.2
Yamamoto, M.3
Nuripa, A.4
Kida, T.5
Kazui, H.6
Hashimoto, R.7
Tanaka, T.8
Kudo, T.9
Yamagata, H.10
Tabara, Y.11
Miki, T.12
Akatsu, H.13
Kosaka, K.14
Funakoshi, E.15
Nishitomi, K.16
Sakaguchi, G.17
Kato, A.18
Hattori, H.19
Uema, T.20
Takeda, M.21
more..
-
78
-
-
33846820241
-
A novel monoclonal antibody DC63 reveals that inhibitor 1 of protein phosphatase 2A is preferentially nuclearly localised in human brain
-
Kovacech B., Kontsekova E., Zilka N., Novak P., Skrabana R., Filipcik P., Iqbal K., Novak M. A novel monoclonal antibody DC63 reveals that inhibitor 1 of protein phosphatase 2A is preferentially nuclearly localised in human brain. FEBS Letters 2007, 581:617-622.
-
(2007)
FEBS Letters
, vol.581
, pp. 617-622
-
-
Kovacech, B.1
Kontsekova, E.2
Zilka, N.3
Novak, P.4
Skrabana, R.5
Filipcik, P.6
Iqbal, K.7
Novak, M.8
-
79
-
-
0030723127
-
Casein kinase 1 is tightly associated with paired-helical filaments isolated from Alzheimer's disease brain
-
Kuret J., Johnson G.S., Cha D., Christenson E.R., DeMaggio A.J., Hoekstra M.F. Casein kinase 1 is tightly associated with paired-helical filaments isolated from Alzheimer's disease brain. Journal of Neurochemistry 1997, 69:2506-2515.
-
(1997)
Journal of Neurochemistry
, vol.69
, pp. 2506-2515
-
-
Kuret, J.1
Johnson, G.S.2
Cha, D.3
Christenson, E.R.4
DeMaggio, A.J.5
Hoekstra, M.F.6
-
80
-
-
64949088215
-
Homocysteine-induced acute excitotoxicity in cerebellar granule cells in vitro is accompanied by PP2A-mediated dephosphorylation of tau
-
Kuszczyk M., Gordon-Krajcer W., Lazarewicz J.W. Homocysteine-induced acute excitotoxicity in cerebellar granule cells in vitro is accompanied by PP2A-mediated dephosphorylation of tau. Neurochemistry International 2009, 55:174-180.
-
(2009)
Neurochemistry International
, vol.55
, pp. 174-180
-
-
Kuszczyk, M.1
Gordon-Krajcer, W.2
Lazarewicz, J.W.3
-
81
-
-
0029970593
-
Neurofibrillary tangles of Alzheimer's disease brains contain 14-3-3 proteins
-
Layfield R., Fergusson J., Aitken A., Lowe J., Landon M., Mayer R.J. Neurofibrillary tangles of Alzheimer's disease brains contain 14-3-3 proteins. Neuroscience Letters 1996, 209:57-60.
-
(1996)
Neuroscience Letters
, vol.209
, pp. 57-60
-
-
Layfield, R.1
Fergusson, J.2
Aitken, A.3
Lowe, J.4
Landon, M.5
Mayer, R.J.6
-
82
-
-
38349033673
-
The microtubule-associated protein tau is phosphorylated by Syk
-
Lebouvier T., Scales T.M., Hanger D.P., Geahlen R.L., Lardeux B., Reynolds C.H., Anderton B.H., Derkinderen P. The microtubule-associated protein tau is phosphorylated by Syk. Biochimica et Biophysica Acta 2008, 1783:188-192.
-
(2008)
Biochimica et Biophysica Acta
, vol.1783
, pp. 188-192
-
-
Lebouvier, T.1
Scales, T.M.2
Hanger, D.P.3
Geahlen, R.L.4
Lardeux, B.5
Reynolds, C.H.6
Anderton, B.H.7
Derkinderen, P.8
-
83
-
-
70349133040
-
The microtubule-associated protein tau is also phosphorylated on tyrosine
-
Lebouvier T., Scales T.M., Williamson R., Noble W., Duyckaerts C., Hanger D.P., Reynolds C.H., Anderton B.H., Derkinderen P. The microtubule-associated protein tau is also phosphorylated on tyrosine. Journal of Alzheimer's Disease 2009.
-
(2009)
Journal of Alzheimer's Disease
-
-
Lebouvier, T.1
Scales, T.M.2
Williamson, R.3
Noble, W.4
Duyckaerts, C.5
Hanger, D.P.6
Reynolds, C.H.7
Anderton, B.H.8
Derkinderen, P.9
-
84
-
-
12144288564
-
Phosphorylation of tau by fyn: implications for Alzheimer's disease
-
Lee G., Thangavel R., Sharma V.M., Litersky J.M., Bhaskar K., Fang S.M., Do L.H., Andreadis A., Van Hoesen G., Ksiezak-Reding H. Phosphorylation of tau by fyn: implications for Alzheimer's disease. Journal of Neuroscience 2004, 24:2304-2312.
-
(2004)
Journal of Neuroscience
, vol.24
, pp. 2304-2312
-
-
Lee, G.1
Thangavel, R.2
Sharma, V.M.3
Litersky, J.M.4
Bhaskar, K.5
Fang, S.M.6
Do, L.H.7
Andreadis, A.8
Van Hoesen, G.9
Ksiezak-Reding, H.10
-
85
-
-
84863867694
-
Developing therapeutic approaches to tau, selected kinases, and related neuronal protein targets
-
Lee V.M., Brunden K.R., Hutton M., Trojanowski J.Q. Developing therapeutic approaches to tau, selected kinases, and related neuronal protein targets. Cold Spring Harbor Perspectives in Medicine 2012, 1:a006437.
-
(2012)
Cold Spring Harbor Perspectives in Medicine
, vol.1
-
-
Lee, V.M.1
Brunden, K.R.2
Hutton, M.3
Trojanowski, J.Q.4
-
86
-
-
10744229024
-
Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity
-
Leulliot N., Quevillon-Cheruel S., Sorel I., de La Sierra-Gallay I.L., Collinet B., Graille M., Blondeau K., Bettache N., Poupon A., Janin J., van Tilbeurgh H. Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity. Journal of Biological Chemistry 2004, 279:8351-8358.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 8351-8358
-
-
Leulliot, N.1
Quevillon-Cheruel, S.2
Sorel, I.3
de La Sierra-Gallay, I.L.4
Collinet, B.5
Graille, M.6
Blondeau, K.7
Bettache, N.8
Poupon, A.9
Janin, J.10
van Tilbeurgh, H.11
-
87
-
-
72049105843
-
Involvement of the PTEN-AKT-FOXO3a pathway in neuronal apoptosis in developing rat brain after hypoxia-ischemia
-
Li D., Qu Y., Mao M., Zhang X., Li J., Ferriero D., Mu D. Involvement of the PTEN-AKT-FOXO3a pathway in neuronal apoptosis in developing rat brain after hypoxia-ischemia. Journal of Cerebral Blood Flow and Metabolism 2009.
-
(2009)
Journal of Cerebral Blood Flow and Metabolism
-
-
Li, D.1
Qu, Y.2
Mao, M.3
Zhang, X.4
Li, J.5
Ferriero, D.6
Mu, D.7
-
88
-
-
2442465965
-
Memantine inhibits and reverses the Alzheimer type abnormal hyperphosphorylation of tau and associated neurodegeneration
-
Li L., Sengupta A., Haque N., Grundke-Iqbal I., Iqbal K. Memantine inhibits and reverses the Alzheimer type abnormal hyperphosphorylation of tau and associated neurodegeneration. FEBS Letters 2004, 566:261-269.
-
(2004)
FEBS Letters
, vol.566
, pp. 261-269
-
-
Li, L.1
Sengupta, A.2
Haque, N.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
89
-
-
0031603730
-
I1PP2A and I2PP2A, Two potent protein phosphatase 2A-specific inhibitor proteins
-
Li M., Damuni Z. I1PP2A and I2PP2A, Two potent protein phosphatase 2A-specific inhibitor proteins. Methods in Molecular Biology 1998, 93:59-66.
-
(1998)
Methods in Molecular Biology
, vol.93
, pp. 59-66
-
-
Li, M.1
Damuni, Z.2
-
90
-
-
0028931302
-
Purification and characterization of two potent heat-stable protein inhibitors of protein phosphatase 2A from bovine kidney
-
Li M., Guo H., Damuni Z. Purification and characterization of two potent heat-stable protein inhibitors of protein phosphatase 2A from bovine kidney. Biochemistry 1995, 34:1988-1996.
-
(1995)
Biochemistry
, vol.34
, pp. 1988-1996
-
-
Li, M.1
Guo, H.2
Damuni, Z.3
-
91
-
-
0029665228
-
Molecular identification of I1PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A
-
Li M., Makkinje A., Damuni Z. Molecular identification of I1PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A. Biochemistry 1996, 35:6998-7002.
-
(1996)
Biochemistry
, vol.35
, pp. 6998-7002
-
-
Li, M.1
Makkinje, A.2
Damuni, Z.3
-
92
-
-
29244459434
-
Activation of glycogen synthase kinase-3 induces Alzheimer-like tau hyperphosphorylation in rat hippocampus slices in culture
-
Li X., Lu F., Tian Q., Yang Y., Wang Q., Wang J.Z. Activation of glycogen synthase kinase-3 induces Alzheimer-like tau hyperphosphorylation in rat hippocampus slices in culture. Journal of Neural Transmission 2006, 113:93-102.
-
(2006)
Journal of Neural Transmission
, vol.113
, pp. 93-102
-
-
Li, X.1
Lu, F.2
Tian, Q.3
Yang, Y.4
Wang, Q.5
Wang, J.Z.6
-
93
-
-
0035423033
-
Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus
-
Li X., Yost H.J., Virshup D.M., Seeling J.M. Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus. EMBO Journal 2001, 20:4122-4131.
-
(2001)
EMBO Journal
, vol.20
, pp. 4122-4131
-
-
Li, X.1
Yost, H.J.2
Virshup, D.M.3
Seeling, J.M.4
-
94
-
-
84860293520
-
AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation
-
Li X.H., Lv B.L., Xie J.Z., Liu J., Zhou X.W., Wang J.Z. AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation. Neurobiology of Aging 2011.
-
(2011)
Neurobiology of Aging
-
-
Li, X.H.1
Lv, B.L.2
Xie, J.Z.3
Liu, J.4
Zhou, X.W.5
Wang, J.Z.6
-
95
-
-
47849120642
-
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome
-
Liang Z., Liu F., Iqbal K., Grundke-Iqbal I., Wegiel J., Gong C.X. Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. Journal of Alzheimer's Disease 2008, 13:295-302.
-
(2008)
Journal of Alzheimer's Disease
, vol.13
, pp. 295-302
-
-
Liang, Z.1
Liu, F.2
Iqbal, K.3
Grundke-Iqbal, I.4
Wegiel, J.5
Gong, C.X.6
-
96
-
-
0032555642
-
Protein phosphatase 1 is targeted to microtubules by the microtubule-associated protein tau
-
Liao H., Li Y., Brautigan D.L., Gundersen G.G. Protein phosphatase 1 is targeted to microtubules by the microtubule-associated protein tau. Journal of Biological Chemistry 1998, 273:21901-21908.
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 21901-21908
-
-
Liao, H.1
Li, Y.2
Brautigan, D.L.3
Gundersen, G.G.4
-
97
-
-
0029899091
-
Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356
-
Litersky J.M., Johnson G.V., Jakes R., Goedert M., Lee M., Seubert P. Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356. Biochemical Journal 1996, 316(Pt 2):655-660.
-
(1996)
Biochemical Journal
, vol.316
, Issue.PART. 2
, pp. 655-660
-
-
Litersky, J.M.1
Johnson, G.V.2
Jakes, R.3
Goedert, M.4
Lee, M.5
Seubert, P.6
-
98
-
-
27644478606
-
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
-
Liu F., Grundke-Iqbal I., Iqbal K., Gong C.X. Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. European Journal of Neuroscience 2005, 22:1942-1950.
-
(2005)
European Journal of Neuroscience
, vol.22
, pp. 1942-1950
-
-
Liu, F.1
Grundke-Iqbal, I.2
Iqbal, K.3
Gong, C.X.4
-
99
-
-
12544251263
-
Dephosphorylation of tau by protein phosphatase 5: impairment in Alzheimer's disease
-
Liu F., Iqbal K., Grundke-Iqbal I., Rossie S., Gong C.X. Dephosphorylation of tau by protein phosphatase 5: impairment in Alzheimer's disease. Journal of Biological Chemistry 2005, 280:1790-1796.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 1790-1796
-
-
Liu, F.1
Iqbal, K.2
Grundke-Iqbal, I.3
Rossie, S.4
Gong, C.X.5
-
100
-
-
0037049240
-
Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5
-
Liu F., Zaidi T., Iqbal K., Grundke-Iqbal I., Gong C.X. Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5. Neuroscience 2002, 115:829-837.
-
(2002)
Neuroscience
, vol.115
, pp. 829-837
-
-
Liu, F.1
Zaidi, T.2
Iqbal, K.3
Grundke-Iqbal, I.4
Gong, C.X.5
-
101
-
-
0027157178
-
FK506 and ciclosporin: molecular probes for studying intracellular signal transduction
-
Liu J. FK506 and ciclosporin: molecular probes for studying intracellular signal transduction. Trends in Pharmacological Sciences 1993, 14:182-188.
-
(1993)
Trends in Pharmacological Sciences
, vol.14
, pp. 182-188
-
-
Liu, J.1
-
102
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
-
Liu J., Farmer J.D., Lane W.S., Friedman J., Weissman I., Schreiber S.L. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 1991, 66:807-815.
-
(1991)
Cell
, vol.66
, pp. 807-815
-
-
Liu, J.1
Farmer, J.D.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
103
-
-
38049166147
-
FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma
-
Liu Q., Zhao X., Frissora F., Ma Y., Santhanam R., Jarjoura D., Lehman A., Perrotti D., Chen C.S., Dalton J.T., Muthusamy N., Byrd J.C. FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma. Blood 2008, 111:275-284.
-
(2008)
Blood
, vol.111
, pp. 275-284
-
-
Liu, Q.1
Zhao, X.2
Frissora, F.3
Ma, Y.4
Santhanam, R.5
Jarjoura, D.6
Lehman, A.7
Perrotti, D.8
Chen, C.S.9
Dalton, J.T.10
Muthusamy, N.11
Byrd, J.C.12
-
104
-
-
41149086325
-
Phosphorylated PP2A (tyrosine 307) is associated with Alzheimer neurofibrillary pathology
-
Liu R., Zhou X.W., Tanila H., Bjorkdahl C., Wang J.Z., Guan Z.Z., Cao Y., Gustafsson J.A., Winblad B., Pei J.J. Phosphorylated PP2A (tyrosine 307) is associated with Alzheimer neurofibrillary pathology. Journal of Cellular and Molecular Medicine 2008, 12:241-257.
-
(2008)
Journal of Cellular and Molecular Medicine
, vol.12
, pp. 241-257
-
-
Liu, R.1
Zhou, X.W.2
Tanila, H.3
Bjorkdahl, C.4
Wang, J.Z.5
Guan, Z.Z.6
Cao, Y.7
Gustafsson, J.A.8
Winblad, B.9
Pei, J.J.10
-
105
-
-
9644257211
-
Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain
-
Liu S.J., Zhang J.Y., Li H.L., Fang Z.Y., Wang Q., Deng H.M., Gong C.X., Grundke-Iqbal I., Iqbal K., Wang J.Z. Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain. Journal of Biological Chemistry 2004, 279:50078-50088.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 50078-50088
-
-
Liu, S.J.1
Zhang, J.Y.2
Li, H.L.3
Fang, Z.Y.4
Wang, Q.5
Deng, H.M.6
Gong, C.X.7
Grundke-Iqbal, I.8
Iqbal, K.9
Wang, J.Z.10
-
106
-
-
2642530239
-
An inactive protein phosphatase 2A population is associated with methylesterase and can be re-activated by the phosphotyrosyl phosphatase activator
-
Longin S., Jordens J., Martens E., Stevens I., Janssens V., Rondelez E., De Baere I., Derua R., Waelkens E., Goris J., Van Hoof C. An inactive protein phosphatase 2A population is associated with methylesterase and can be re-activated by the phosphotyrosyl phosphatase activator. Biochemical Journal 2004, 380:111-119.
-
(2004)
Biochemical Journal
, vol.380
, pp. 111-119
-
-
Longin, S.1
Jordens, J.2
Martens, E.3
Stevens, I.4
Janssens, V.5
Rondelez, E.6
De Baere, I.7
Derua, R.8
Waelkens, E.9
Goris, J.10
Van Hoof, C.11
-
107
-
-
34848843828
-
Selection of protein phosphatase 2A regulatory subunits is mediated by the C terminus of the catalytic Subunit
-
Longin S., Zwaenepoel K., Louis J.V., Dilworth S., Goris J., Janssens V. Selection of protein phosphatase 2A regulatory subunits is mediated by the C terminus of the catalytic Subunit. Journal of Biological Chemistry 2007, 282:26971-26980.
-
(2007)
Journal of Biological Chemistry
, vol.282
, pp. 26971-26980
-
-
Longin, S.1
Zwaenepoel, K.2
Louis, J.V.3
Dilworth, S.4
Goris, J.5
Janssens, V.6
-
108
-
-
36549071636
-
Spatial control of protein phosphatase 2A (de)methylation
-
Longin S., Zwaenepoel K., Martens E., Louis J.V., Rondelez E., Goris J., Janssens V. Spatial control of protein phosphatase 2A (de)methylation. Experimental Cell Research 2008, 314:68-81.
-
(2008)
Experimental Cell Research
, vol.314
, pp. 68-81
-
-
Longin, S.1
Zwaenepoel, K.2
Martens, E.3
Louis, J.V.4
Rondelez, E.5
Goris, J.6
Janssens, V.7
-
109
-
-
0035914309
-
Interaction between protein phosphatase 5 and the A subunit of protein phosphatase 2A: evidence for a heterotrimeric form of protein phosphatase 5
-
Lubert E.J., Hong Y., Sarge K.D. Interaction between protein phosphatase 5 and the A subunit of protein phosphatase 2A: evidence for a heterotrimeric form of protein phosphatase 5. Journal of Biological Chemistry 2001, 276:38582-38587.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 38582-38587
-
-
Lubert, E.J.1
Hong, Y.2
Sarge, K.D.3
-
110
-
-
34547183507
-
Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies
-
Luo W., Dou F., Rodina A., Chip S., Kim J., Zhao Q., Moulick K., Aguirre J., Wu N., Greengard P., Chiosis G. Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:9511-9516.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 9511-9516
-
-
Luo, W.1
Dou, F.2
Rodina, A.3
Chip, S.4
Kim, J.5
Zhao, Q.6
Moulick, K.7
Aguirre, J.8
Wu, N.9
Greengard, P.10
Chiosis, G.11
-
111
-
-
0025635610
-
Tautomycin from the bacterium Streptomyces verticillatus, another potent and specific inhibitor of protein phosphatases 1 and 2A
-
MacKintosh C., Klumpp S. Tautomycin from the bacterium Streptomyces verticillatus, another potent and specific inhibitor of protein phosphatases 1 and 2A. FEBS Letters 1990, 277:137-140.
-
(1990)
FEBS Letters
, vol.277
, pp. 137-140
-
-
MacKintosh, C.1
Klumpp, S.2
-
112
-
-
27744547991
-
SET protein (TAF1beta, I2PP2A) is involved in neuronal apoptosis induced by an amyloid precursor protein cytoplasmic subdomain
-
Madeira A., Pommet J.M., Prochiantz A., Allinquant B. SET protein (TAF1beta, I2PP2A) is involved in neuronal apoptosis induced by an amyloid precursor protein cytoplasmic subdomain. FASEB Journal 2005, 19:1905-1907.
-
(2005)
FASEB Journal
, vol.19
, pp. 1905-1907
-
-
Madeira, A.1
Pommet, J.M.2
Prochiantz, A.3
Allinquant, B.4
-
113
-
-
79952105548
-
Post-translational modifications of tau protein: implications for Alzheimer's disease
-
Martin L., Latypova X., Terro F. Post-translational modifications of tau protein: implications for Alzheimer's disease. Neurochemistry International 2011, 58:458-471.
-
(2011)
Neurochemistry International
, vol.58
, pp. 458-471
-
-
Martin, L.1
Latypova, X.2
Terro, F.3
-
114
-
-
58349114277
-
Inhibition of glycogen synthase kinase-3beta downregulates total tau proteins in cultured neurons and its reversal by the blockade of protein phosphatase-2A
-
Martin L., Magnaudeix A., Esclaire F., Yardin C., Terro F. Inhibition of glycogen synthase kinase-3beta downregulates total tau proteins in cultured neurons and its reversal by the blockade of protein phosphatase-2A. Brain Research 2009, 1252:66-75.
-
(2009)
Brain Research
, vol.1252
, pp. 66-75
-
-
Martin, L.1
Magnaudeix, A.2
Esclaire, F.3
Yardin, C.4
Terro, F.5
-
115
-
-
80052634341
-
The new indirubin derivative inhibitors of glycogen synthase kinase-3,6-BIDECO and 6-BIMYEO, prevent tau phosphorylation and apoptosis induced by the inhibition of protein phosphatase-2A by okadaic acid in cultured neurons
-
Martin L., Magnaudeix A., Wilson C.M., Yardin C., Terro F. The new indirubin derivative inhibitors of glycogen synthase kinase-3,6-BIDECO and 6-BIMYEO, prevent tau phosphorylation and apoptosis induced by the inhibition of protein phosphatase-2A by okadaic acid in cultured neurons. Journal of Neuroscience Research 2011, 89:1802-1811.
-
(2011)
Journal of Neuroscience Research
, vol.89
, pp. 1802-1811
-
-
Martin, L.1
Magnaudeix, A.2
Wilson, C.M.3
Yardin, C.4
Terro, F.5
-
116
-
-
79960360530
-
Tau phosphorylation and neuronal apoptosis induced by the blockade of PP2A preferentially involve GSK3beta
-
Martin L., Page G., Terro F. Tau phosphorylation and neuronal apoptosis induced by the blockade of PP2A preferentially involve GSK3beta. Neurochemistry International 2011, 59:235-250.
-
(2011)
Neurochemistry International
, vol.59
, pp. 235-250
-
-
Martin, L.1
Page, G.2
Terro, F.3
-
117
-
-
0027787984
-
Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ
-
Merrill A.H., van Echten G., Wang E., Sandhoff K. Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ. Journal of Biological Chemistry 1993, 268:27299-27306.
-
(1993)
Journal of Biological Chemistry
, vol.268
, pp. 27299-27306
-
-
Merrill, A.H.1
van Echten, G.2
Wang, E.3
Sandhoff, K.4
-
118
-
-
33748040410
-
Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells
-
Messner D.J., Romeo C., Boynton A., Rossie S. Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells. Journal of Cellular Biochemistry 2006, 99:241-255.
-
(2006)
Journal of Cellular Biochemistry
, vol.99
, pp. 241-255
-
-
Messner, D.J.1
Romeo, C.2
Boynton, A.3
Rossie, S.4
-
120
-
-
0035929178
-
Tautomycetin is a novel and specific inhibitor of serine/threonine protein phosphatase type 1, PP1
-
Mitsuhashi S., Matsuura N., Ubukata M., Oikawa H., Shima H., Kikuchi K. Tautomycetin is a novel and specific inhibitor of serine/threonine protein phosphatase type 1, PP1. Biochemical and Biophysical Research Communications 2001, 287:328-331.
-
(2001)
Biochemical and Biophysical Research Communications
, vol.287
, pp. 328-331
-
-
Mitsuhashi, S.1
Matsuura, N.2
Ubukata, M.3
Oikawa, H.4
Shima, H.5
Kikuchi, K.6
-
121
-
-
0028899714
-
Proline-directed and non-proline-directed phosphorylation of PHF-tau
-
Morishima-Kawashima M., Hasegawa M., Takio K., Suzuki M., Yoshida H., Titani K., Ihara Y. Proline-directed and non-proline-directed phosphorylation of PHF-tau. Journal of Biological Chemistry 1995, 270:823-829.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 823-829
-
-
Morishima-Kawashima, M.1
Hasegawa, M.2
Takio, K.3
Suzuki, M.4
Yoshida, H.5
Titani, K.6
Ihara, Y.7
-
122
-
-
0035503696
-
Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress
-
Morita K., Saitoh M., Tobiume K., Matsuura H., Enomoto S., Nishitoh H., Ichijo H. Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress. EMBO Journal 2001, 20:6028-6036.
-
(2001)
EMBO Journal
, vol.20
, pp. 6028-6036
-
-
Morita, K.1
Saitoh, M.2
Tobiume, K.3
Matsuura, H.4
Enomoto, S.5
Nishitoh, H.6
Ichijo, H.7
-
123
-
-
4644272703
-
The role of DARPP-32 in the actions of drugs of abuse
-
Nairn A.C., Svenningsson P., Nishi A., Fisone G., Girault J.A., Greengard P. The role of DARPP-32 in the actions of drugs of abuse. Neuropharmacology 2004, 47(Suppl 1):14-23.
-
(2004)
Neuropharmacology
, vol.47
, Issue.SUPPL. 1
, pp. 14-23
-
-
Nairn, A.C.1
Svenningsson, P.2
Nishi, A.3
Fisone, G.4
Girault, J.A.5
Greengard, P.6
-
124
-
-
33847336005
-
Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella
-
Nayeem N., Kerr F., Naumann H., Linehan J., Lovestone S., Brandner S. Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella. Molecular and Cellular Neurosciences 2007, 34:400-408.
-
(2007)
Molecular and Cellular Neurosciences
, vol.34
, pp. 400-408
-
-
Nayeem, N.1
Kerr, F.2
Naumann, H.3
Linehan, J.4
Lovestone, S.5
Brandner, S.6
-
126
-
-
0033553570
-
A protein phosphatase methylesterase PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A
-
Ogris E., Du X., Nelson K.C., Mak E.K., Yu X.X., Lane W.S., Pallas D.C. A protein phosphatase methylesterase PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A. Journal of Biological Chemistry 1999, 274:14382-14391.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 14382-14391
-
-
Ogris, E.1
Du, X.2
Nelson, K.C.3
Mak, E.K.4
Yu, X.X.5
Lane, W.S.6
Pallas, D.C.7
-
128
-
-
0033540060
-
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
-
Patrick G.N., Zukerberg L., Nikolic M., de la Monte S., Dikkes P., Tsai L.H. Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature 1999, 402:615-622.
-
(1999)
Nature
, vol.402
, pp. 615-622
-
-
Patrick, G.N.1
Zukerberg, L.2
Nikolic, M.3
de la Monte, S.4
Dikkes, P.5
Tsai, L.H.6
-
129
-
-
0030614508
-
The regulatory Ser262 of microtubule-associated protein tau is phosphorylated by phosphorylase kinase
-
Paudel H.K. The regulatory Ser262 of microtubule-associated protein tau is phosphorylated by phosphorylase kinase. Journal of Biological Chemistry 1997, 272:1777-1785.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 1777-1785
-
-
Paudel, H.K.1
-
130
-
-
12244279939
-
Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease
-
Pei J.J., Braak H., An W.L., Winblad B., Cowburn R.F., Iqbal K., Grundke-Iqbal I. Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease. Brain Research Molecular Brain Research 2002, 109:45-55.
-
(2002)
Brain Research Molecular Brain Research
, vol.109
, pp. 45-55
-
-
Pei, J.J.1
Braak, H.2
An, W.L.3
Winblad, B.4
Cowburn, R.F.5
Iqbal, K.6
Grundke-Iqbal, I.7
-
131
-
-
0042679509
-
Okadaic-acid-induced inhibition of protein phosphatase 2A produces activation of mitogen-activated protein kinases ERK1/2, MEK1/2, and p70 S6, similar to that in Alzheimer's disease
-
Pei J.J., Gong C.X., An W.L., Winblad B., Cowburn R.F., Grundke-Iqbal I., Iqbal K. Okadaic-acid-induced inhibition of protein phosphatase 2A produces activation of mitogen-activated protein kinases ERK1/2, MEK1/2, and p70 S6, similar to that in Alzheimer's disease. American Journal of Pathology 2003, 163:845-858.
-
(2003)
American Journal of Pathology
, vol.163
, pp. 845-858
-
-
Pei, J.J.1
Gong, C.X.2
An, W.L.3
Winblad, B.4
Cowburn, R.F.5
Grundke-Iqbal, I.6
Iqbal, K.7
-
132
-
-
0030635495
-
Distribution, levels, and activity of glycogen synthase kinase-3 in the Alzheimer disease brain
-
Pei J.J., Tanaka T., Tung Y.C., Braak E., Iqbal K., Grundke-Iqbal I. Distribution, levels, and activity of glycogen synthase kinase-3 in the Alzheimer disease brain. Journal of Neuropathology and Experimental Neurology 1997, 56:70-78.
-
(1997)
Journal of Neuropathology and Experimental Neurology
, vol.56
, pp. 70-78
-
-
Pei, J.J.1
Tanaka, T.2
Tung, Y.C.3
Braak, E.4
Iqbal, K.5
Grundke-Iqbal, I.6
-
133
-
-
43049112747
-
Protein phosphatase 2A (PP2A), a drugable tumor suppressor in Ph1(+) leukemias
-
Perrotti D., Neviani P. Protein phosphatase 2A (PP2A), a drugable tumor suppressor in Ph1(+) leukemias. Cancer and Metastasis Reviews 2008, 27:159-168.
-
(2008)
Cancer and Metastasis Reviews
, vol.27
, pp. 159-168
-
-
Perrotti, D.1
Neviani, P.2
-
134
-
-
0033516947
-
Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation
-
Perry G., Roder H., Nunomura A., Takeda A., Friedlich A.L., Zhu X., Raina A.K., Holbrook N., Siedlak S.L., Harris P.L., Smith M.A. Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport 1999, 10:2411-2415.
-
(1999)
Neuroreport
, vol.10
, pp. 2411-2415
-
-
Perry, G.1
Roder, H.2
Nunomura, A.3
Takeda, A.4
Friedlich, A.L.5
Zhu, X.6
Raina, A.K.7
Holbrook, N.8
Siedlak, S.L.9
Harris, P.L.10
Smith, M.A.11
-
135
-
-
33845757628
-
Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress
-
Poppek D., Keck S., Ermak G., Jung T., Stolzing A., Ullrich O., Davies K.J., Grune T. Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress. Biochemical Journal 2006, 400:511-520.
-
(2006)
Biochemical Journal
, vol.400
, pp. 511-520
-
-
Poppek, D.1
Keck, S.2
Ermak, G.3
Jung, T.4
Stolzing, A.5
Ullrich, O.6
Davies, K.J.7
Grune, T.8
-
136
-
-
77950366745
-
PP2A regulates tau phosphorylation directly and also indirectly via activating GSK-3beta
-
Qian W., Shi J., Yin X., Iqbal K., Grundke-Iqbal I., Gong C.X., Liu F. PP2A regulates tau phosphorylation directly and also indirectly via activating GSK-3beta. Journal of Alzheimer's Disease 2010, 19:1221-1229.
-
(2010)
Journal of Alzheimer's Disease
, vol.19
, pp. 1221-1229
-
-
Qian, W.1
Shi, J.2
Yin, X.3
Iqbal, K.4
Grundke-Iqbal, I.5
Gong, C.X.6
Liu, F.7
-
137
-
-
17644410079
-
Phosphothreonine-212 of Alzheimer abnormally hyperphosphorylated tau is a preferred substrate of protein phosphatase-1
-
Rahman A., Grundke-Iqbal I., Iqbal K. Phosphothreonine-212 of Alzheimer abnormally hyperphosphorylated tau is a preferred substrate of protein phosphatase-1. Neurochemical Research 2005, 30:277-287.
-
(2005)
Neurochemical Research
, vol.30
, pp. 277-287
-
-
Rahman, A.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
138
-
-
31044445372
-
PP2B isolated from human brain preferentially dephosphorylates Ser-262 and Ser-396 of the Alzheimer disease abnormally hyperphosphorylated tau
-
Rahman A., Grundke-Iqbal I., Iqbal K. PP2B isolated from human brain preferentially dephosphorylates Ser-262 and Ser-396 of the Alzheimer disease abnormally hyperphosphorylated tau. Journal of Neural Transmission 2006, 113:219-230.
-
(2006)
Journal of Neural Transmission
, vol.113
, pp. 219-230
-
-
Rahman, A.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
139
-
-
0033178807
-
Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A
-
Resjo S., Oknianska A., Zolnierowicz S., Manganiello V., Degerman E. Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A. Biochemical Journal 1999, 341(Pt 3):839-845.
-
(1999)
Biochemical Journal
, vol.341
, Issue.PART. 3
, pp. 839-845
-
-
Resjo, S.1
Oknianska, A.2
Zolnierowicz, S.3
Manganiello, V.4
Degerman, E.5
-
140
-
-
29244482770
-
PTEN levels in Alzheimer's disease medial temporal cortex
-
Rickle A., Bogdanovic N., Volkmann I., Zhou X., Pei J.J., Winblad B., Cowburn R.F. PTEN levels in Alzheimer's disease medial temporal cortex. Neurochemistry International 2006, 48:114-123.
-
(2006)
Neurochemistry International
, vol.48
, pp. 114-123
-
-
Rickle, A.1
Bogdanovic, N.2
Volkmann, I.3
Zhou, X.4
Pei, J.J.5
Winblad, B.6
Cowburn, R.F.7
-
141
-
-
0033779701
-
Calcineurin: form and function
-
Rusnak F., Mertz P. Calcineurin: form and function. Physiological Reviews 2000, 80:1483-1521.
-
(2000)
Physiological Reviews
, vol.80
, pp. 1483-1521
-
-
Rusnak, F.1
Mertz, P.2
-
142
-
-
0035848717
-
Absence of PPP2R1A mutations in Wilms tumor
-
Ruteshouser E.C., Ashworth L.K., Huff V. Absence of PPP2R1A mutations in Wilms tumor. Oncogene 2001, 20:2050-2054.
-
(2001)
Oncogene
, vol.20
, pp. 2050-2054
-
-
Ruteshouser, E.C.1
Ashworth, L.K.2
Huff, V.3
-
143
-
-
0037151038
-
A functional role for the B56 alpha-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function
-
Ruvolo P.P., Clark W., Mumby M., Gao F., May W.S. A functional role for the B56 alpha-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function. Journal of Biological Chemistry 2002, 277:22847-22852.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 22847-22852
-
-
Ruvolo, P.P.1
Clark, W.2
Mumby, M.3
Gao, F.4
May, W.S.5
-
144
-
-
36849075621
-
DYRK1A-mediated hyperphosphorylation of tau. A functional link between Down syndrome and Alzheimer disease
-
Ryoo S.R., Jeong H.K., Radnaabazar C., Yoo J.J., Cho H.J., Lee H.W., Kim I.S., Cheon Y.H., Ahn Y.S., Chung S.H., Song W.J. DYRK1A-mediated hyperphosphorylation of tau. A functional link between Down syndrome and Alzheimer disease. Journal of Biological Chemistry 2007, 282:34850-34857.
-
(2007)
Journal of Biological Chemistry
, vol.282
, pp. 34850-34857
-
-
Ryoo, S.R.1
Jeong, H.K.2
Radnaabazar, C.3
Yoo, J.J.4
Cho, H.J.5
Lee, H.W.6
Kim, I.S.7
Cheon, Y.H.8
Ahn, Y.S.9
Chung, S.H.10
Song, W.J.11
-
145
-
-
0028865376
-
In situ dephosphorylation of tau by protein phosphatase 2A and 2B in fetal rat primary cultured neurons
-
Saito T., Ishiguro K., Uchida T., Miyamoto E., Kishimoto T., Hisanaga S. In situ dephosphorylation of tau by protein phosphatase 2A and 2B in fetal rat primary cultured neurons. FEBS Letters 1995, 376:238-242.
-
(1995)
FEBS Letters
, vol.376
, pp. 238-242
-
-
Saito, T.1
Ishiguro, K.2
Uchida, T.3
Miyamoto, E.4
Kishimoto, T.5
Hisanaga, S.6
-
146
-
-
70349312814
-
Protein phosphatase 5 protects neurons against amyloid-beta toxicity
-
Sanchez-Ortiz E., Hahm B.K., Armstrong D.L., Rossie S. Protein phosphatase 5 protects neurons against amyloid-beta toxicity. Journal of Neurochemistry 2009, 111:391-402.
-
(2009)
Journal of Neurochemistry
, vol.111
, pp. 391-402
-
-
Sanchez-Ortiz, E.1
Hahm, B.K.2
Armstrong, D.L.3
Rossie, S.4
-
147
-
-
33746879943
-
Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation
-
Sato S., Cerny R.L., Buescher J.L., Ikezu T. Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation. Journal of Neurochemistry 2006, 98:1573-1584.
-
(2006)
Journal of Neurochemistry
, vol.98
, pp. 1573-1584
-
-
Sato, S.1
Cerny, R.L.2
Buescher, J.L.3
Ikezu, T.4
-
148
-
-
0347624594
-
Activation of the RAS/cyclic AMP pathway suppresses a TOR deficiency in yeast
-
Schmelzle T., Beck T., Martin D.E., Hall M.N. Activation of the RAS/cyclic AMP pathway suppresses a TOR deficiency in yeast. Molecular and Cellular Biology 2004, 24:338-351.
-
(2004)
Molecular and Cellular Biology
, vol.24
, pp. 338-351
-
-
Schmelzle, T.1
Beck, T.2
Martin, D.E.3
Hall, M.N.4
-
149
-
-
2442601508
-
Bisperoxovanadium compounds are potent PTEN inhibitors
-
Schmid A.C., Byrne R.D., Vilar R., Woscholski R. Bisperoxovanadium compounds are potent PTEN inhibitors. FEBS Letters 2004, 566:35-38.
-
(2004)
FEBS Letters
, vol.566
, pp. 35-38
-
-
Schmid, A.C.1
Byrne, R.D.2
Vilar, R.3
Woscholski, R.4
-
150
-
-
0034622242
-
Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases
-
Schwab C., DeMaggio A.J., Ghoshal N., Binder L.I., Kuret J., McGeer P.L. Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases. Neurobiology of Aging 2000, 21:503-510.
-
(2000)
Neurobiology of Aging
, vol.21
, pp. 503-510
-
-
Schwab, C.1
DeMaggio, A.J.2
Ghoshal, N.3
Binder, L.I.4
Kuret, J.5
McGeer, P.L.6
-
151
-
-
0031052339
-
Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5
-
Sengupta A., Wu Q., Grundke-Iqbal I., Iqbal K., Singh T.J. Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5. Molecular and Cellular Biochemistry 1997, 167:99-105.
-
(1997)
Molecular and Cellular Biochemistry
, vol.167
, pp. 99-105
-
-
Sengupta, A.1
Wu, Q.2
Grundke-Iqbal, I.3
Iqbal, K.4
Singh, T.J.5
-
152
-
-
0028978701
-
Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau
-
Seubert P., Mawal-Dewan M., Barbour R., Jakes R., Goedert M., Johnson G.V., Litersky J.M., Schenk D., Lieberburg I., Trojanowski J.Q., et al. Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau. Journal of Biological Chemistry 1995, 270:18917-18922.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 18917-18922
-
-
Seubert, P.1
Mawal-Dewan, M.2
Barbour, R.3
Jakes, R.4
Goedert, M.5
Johnson, G.V.6
Litersky, J.M.7
Schenk, D.8
Lieberburg, I.9
Trojanowski, J.Q.10
-
154
-
-
0027447602
-
The protein tyrosine kinase, fyn, in Alzheimer's disease pathology
-
Shirazi S.K., Wood J.G. The protein tyrosine kinase, fyn, in Alzheimer's disease pathology. Neuroreport 1993, 4:435-437.
-
(1993)
Neuroreport
, vol.4
, pp. 435-437
-
-
Shirazi, S.K.1
Wood, J.G.2
-
155
-
-
0034727889
-
JNK activation is associated with intracellular beta-amyloid accumulation
-
Shoji M., Iwakami N., Takeuchi S., Waragai M., Suzuki M., Kanazawa I., Lippa C.F., Ono S., Okazawa H. JNK activation is associated with intracellular beta-amyloid accumulation. Brain Research Molecular Brain Research 2000, 85:221-233.
-
(2000)
Brain Research Molecular Brain Research
, vol.85
, pp. 221-233
-
-
Shoji, M.1
Iwakami, N.2
Takeuchi, S.3
Waragai, M.4
Suzuki, M.5
Kanazawa, I.6
Lippa, C.F.7
Ono, S.8
Okazawa, H.9
-
156
-
-
0029888525
-
Calcium/calmodulin-dependent protein kinase II phosphorylates tau at Ser-262 but only partially inhibits its binding to microtubules
-
Singh T.J., Wang J.Z., Novak M., Kontzekova E., Grundke-Iqbal I., Iqbal K. Calcium/calmodulin-dependent protein kinase II phosphorylates tau at Ser-262 but only partially inhibits its binding to microtubules. FEBS Letters 1996, 387:145-148.
-
(1996)
FEBS Letters
, vol.387
, pp. 145-148
-
-
Singh, T.J.1
Wang, J.Z.2
Novak, M.3
Kontzekova, E.4
Grundke-Iqbal, I.5
Iqbal, K.6
-
157
-
-
0030928118
-
Purification of a fatty acid-stimulated protein-serine/threonine phosphatase from bovine brain and its identification as a homolog of protein phosphatase 5
-
Skinner J., Sinclair C., Romeo C., Armstrong D., Charbonneau H., Rossie S. Purification of a fatty acid-stimulated protein-serine/threonine phosphatase from bovine brain and its identification as a homolog of protein phosphatase 5. Journal of Biological Chemistry 1997, 272:22464-22471.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 22464-22471
-
-
Skinner, J.1
Sinclair, C.2
Romeo, C.3
Armstrong, D.4
Charbonneau, H.5
Rossie, S.6
-
158
-
-
71849117415
-
Estrogen partially down-regulates PTEN to prevent apoptosis in VSC4. 1 motoneurons following exposure to IFN-gamma
-
Smith J.A., Zhang R., Varma A.K., Das A., Ray S.K., Banik N.L. Estrogen partially down-regulates PTEN to prevent apoptosis in VSC4. 1 motoneurons following exposure to IFN-gamma. Brain Research 2009.
-
(2009)
Brain Research
-
-
Smith, J.A.1
Zhang, R.2
Varma, A.K.3
Das, A.4
Ray, S.K.5
Banik, N.L.6
-
159
-
-
75749112450
-
Accumulation of tumor-suppressor PTEN in Alzheimer neurofibrillary tangles
-
Sonoda Y., Mukai H., Matsuo K., Takahashi M., Ono Y., Maeda K., Akiyama H., Kawamata T. Accumulation of tumor-suppressor PTEN in Alzheimer neurofibrillary tangles. Neuroscience Letters 2010, 471:20-24.
-
(2010)
Neuroscience Letters
, vol.471
, pp. 20-24
-
-
Sonoda, Y.1
Mukai, H.2
Matsuo, K.3
Takahashi, M.4
Ono, Y.5
Maeda, K.6
Akiyama, H.7
Kawamata, T.8
-
160
-
-
5644293035
-
3rd Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis
-
Sontag E., Hladik C., Montgomery L., Luangpirom A., Mudrak I., Ogris E., White C.L. 3rd Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis. Journal of Neuropathology and Experimental Neurology 2004, 63:1080-1091.
-
(2004)
Journal of Neuropathology and Experimental Neurology
, vol.63
, pp. 1080-1091
-
-
Sontag, E.1
Hladik, C.2
Montgomery, L.3
Luangpirom, A.4
Mudrak, I.5
Ogris, E.6
White, C.L.7
-
161
-
-
1842510667
-
3rd Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology
-
Sontag E., Luangpirom A., Hladik C., Mudrak I., Ogris E., Speciale S., White C.L. 3rd Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology. Journal of Neuropathology and Experimental Neurology 2004, 63:287-301.
-
(2004)
Journal of Neuropathology and Experimental Neurology
, vol.63
, pp. 287-301
-
-
Sontag, E.1
Luangpirom, A.2
Hladik, C.3
Mudrak, I.4
Ogris, E.5
Speciale, S.6
White, C.L.7
-
162
-
-
0033520355
-
3rd, Mumby MC, Bloom GS Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies
-
Sontag E., Nunbhakdi-Craig V., Lee G., Brandt R., Kamibayashi C., Kuret J., White C.L. 3rd, Mumby MC, Bloom GS Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies. Journal of Biological Chemistry 1999, 274:25490-25498.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 25490-25498
-
-
Sontag, E.1
Nunbhakdi-Craig, V.2
Lee, G.3
Brandt, R.4
Kamibayashi, C.5
Kuret, J.6
White, C.L.7
-
163
-
-
33947328858
-
Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation
-
Sontag E., Nunbhakdi-Craig V., Sontag J.M., Diaz-Arrastia R., Ogris E., Dayal S., Lentz S.R., Arning E., Bottiglieri T. Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation. Journal of Neuroscience 2007, 27:2751-2759.
-
(2007)
Journal of Neuroscience
, vol.27
, pp. 2751-2759
-
-
Sontag, E.1
Nunbhakdi-Craig, V.2
Sontag, J.M.3
Diaz-Arrastia, R.4
Ogris, E.5
Dayal, S.6
Lentz, S.R.7
Arning, E.8
Bottiglieri, T.9
-
164
-
-
58149213742
-
Folate deficiency induces in vitro and mouse brain region-specific downregulation of leucine carboxyl methyltransferase-1 and protein phosphatase 2A B(alpha) subunit expression that correlate with enhanced tau phosphorylation
-
Sontag J.M., Nunbhakdi-Craig V., Montgomery L., Arning E., Bottiglieri T., Sontag E. Folate deficiency induces in vitro and mouse brain region-specific downregulation of leucine carboxyl methyltransferase-1 and protein phosphatase 2A B(alpha) subunit expression that correlate with enhanced tau phosphorylation. Journal of Neuroscience 2008, 28:11477-11487.
-
(2008)
Journal of Neuroscience
, vol.28
, pp. 11477-11487
-
-
Sontag, J.M.1
Nunbhakdi-Craig, V.2
Montgomery, L.3
Arning, E.4
Bottiglieri, T.5
Sontag, E.6
-
165
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck P.A., Pershouse M.A., Jasser S.A., Yung W.K., Lin H., Ligon A.H., Langford L.A., Baumgard M.L., Hattier T., Davis T., Frye C., Hu R., Swedlund B., Teng D.H., Tavtigian S.V. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nature Genetics 1997, 15:356-362.
-
(1997)
Nature Genetics
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
Frye, C.11
Hu, R.12
Swedlund, B.13
Teng, D.H.14
Tavtigian, S.V.15
-
166
-
-
0037728833
-
Inhibition of protein phosphatase 2A- and protein phosphatase 1-induced tau hyperphosphorylation and impairment of spatial memory retention in rats
-
Sun L., Liu S.Y., Zhou X.W., Wang X.C., Liu R., Wang Q., Wang J.Z. Inhibition of protein phosphatase 2A- and protein phosphatase 1-induced tau hyperphosphorylation and impairment of spatial memory retention in rats. Neuroscience 2003, 118:1175-1182.
-
(2003)
Neuroscience
, vol.118
, pp. 1175-1182
-
-
Sun, L.1
Liu, S.Y.2
Zhou, X.W.3
Wang, X.C.4
Liu, R.5
Wang, Q.6
Wang, J.Z.7
-
167
-
-
2942589223
-
Increased MAP kinase activity in Alzheimer's and Down syndrome but not in schizophrenia human brain
-
Swatton J.E., Sellers L.A., Faull R.L., Holland A., Iritani S., Bahn S. Increased MAP kinase activity in Alzheimer's and Down syndrome but not in schizophrenia human brain. European Journal of Neuroscience 2004, 19:2711-2719.
-
(2004)
European Journal of Neuroscience
, vol.19
, pp. 2711-2719
-
-
Swatton, J.E.1
Sellers, L.A.2
Faull, R.L.3
Holland, A.4
Iritani, S.5
Bahn, S.6
-
168
-
-
0035971151
-
Phosphorylation of tau is regulated by PKN
-
Taniguchi T., Kawamata T., Mukai H., Hasegawa H., Isagawa T., Yasuda M., Hashimoto T., Terashima A., Nakai M., Mori H., Ono Y., Tanaka C. Phosphorylation of tau is regulated by PKN. Journal of Biological Chemistry 2001, 276:10025-10031.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 10025-10031
-
-
Taniguchi, T.1
Kawamata, T.2
Mukai, H.3
Hasegawa, H.4
Isagawa, T.5
Yasuda, M.6
Hashimoto, T.7
Terashima, A.8
Nakai, M.9
Mori, H.10
Ono, Y.11
Tanaka, C.12
-
169
-
-
19544362550
-
Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease
-
Tanimukai H., Grundke-Iqbal I., Iqbal K. Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease. American Journal of Pathology 2005, 166:1761-1771.
-
(2005)
American Journal of Pathology
, vol.166
, pp. 1761-1771
-
-
Tanimukai, H.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
170
-
-
67650667479
-
Novel therapeutic strategies for neurodegenerative disease
-
Tanimukai H., Kudo T., Tanaka T., Grundke-Iqbal I., Iqbal K., Takeda M. Novel therapeutic strategies for neurodegenerative disease. Psychogeriatrics 2009, 9:103-109.
-
(2009)
Psychogeriatrics
, vol.9
, pp. 103-109
-
-
Tanimukai, H.1
Kudo, T.2
Tanaka, T.3
Grundke-Iqbal, I.4
Iqbal, K.5
Takeda, M.6
-
171
-
-
2942642325
-
Injection of okadaic acid into the meynert nucleus basalis of rat brain induces decreased acetylcholine level and spatial memory deficit
-
Tian Q., Lin Z.Q., Wang X.C., Chen J., Wang Q., Gong C.X., Wang J.Z. Injection of okadaic acid into the meynert nucleus basalis of rat brain induces decreased acetylcholine level and spatial memory deficit. Neuroscience 2004, 126:277-284.
-
(2004)
Neuroscience
, vol.126
, pp. 277-284
-
-
Tian, Q.1
Lin, Z.Q.2
Wang, X.C.3
Chen, J.4
Wang, Q.5
Gong, C.X.6
Wang, J.Z.7
-
172
-
-
67849099654
-
Biphasic effects of forskolin on tau phosphorylation and spatial memory in rats
-
Tian Q., Zhang J.X., Zhang Y., Wu F., Tang Q., Wang C., Shi Z.Y., Zhang J.H., Liu S., Wang Y., Zhang Q., Wang J.Z. Biphasic effects of forskolin on tau phosphorylation and spatial memory in rats. Journal of Alzheimer's Disease 2009.
-
(2009)
Journal of Alzheimer's Disease
-
-
Tian, Q.1
Zhang, J.X.2
Zhang, Y.3
Wu, F.4
Tang, Q.5
Wang, C.6
Shi, Z.Y.7
Zhang, J.H.8
Liu, S.9
Wang, Y.10
Zhang, Q.11
Wang, J.Z.12
-
173
-
-
0035847102
-
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus, implications for PTEN stability to proteasome-mediated degradation
-
Torres J., Pulido R. The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus, implications for PTEN stability to proteasome-mediated degradation. Journal of Biological Chemistry 2001, 276:993-998.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 993-998
-
-
Torres, J.1
Pulido, R.2
-
174
-
-
77049126656
-
Tau phosphorylated at tyrosine 394 is found in Alzheimer's disease tangles and can be a product of the Abl-related kinase, Arg.
-
Tremblay M.A., Acker C.M., Davies P. Tau phosphorylated at tyrosine 394 is found in Alzheimer's disease tangles and can be a product of the Abl-related kinase, Arg. Journal of Alzheimer's Disease 2010, 19:721-733.
-
(2010)
Journal of Alzheimer's Disease
, vol.19
, pp. 721-733
-
-
Tremblay, M.A.1
Acker, C.M.2
Davies, P.3
-
175
-
-
11844273281
-
Inhibitors of protein phosphatase-2A from human brain structures, immunocytological localization and activities towards dephosphorylation of the Alzheimer type hyperphosphorylated tau
-
Tsujio I., Zaidi T., Xu J., Kotula L., Grundke-Iqbal I., Iqbal K. Inhibitors of protein phosphatase-2A from human brain structures, immunocytological localization and activities towards dephosphorylation of the Alzheimer type hyperphosphorylated tau. FEBS Letters 2005, 579:363-372.
-
(2005)
FEBS Letters
, vol.579
, pp. 363-372
-
-
Tsujio, I.1
Zaidi, T.2
Xu, J.3
Kotula, L.4
Grundke-Iqbal, I.5
Iqbal, K.6
-
176
-
-
4844230325
-
(14-3-3 proteins and zeta isoform containing neurofibrillary tangles in patients with Alzheimer's disease
-
Umahara T., Uchihara T., Tsuchiya K., Nakamura A., Iwamoto T., Ikeda K., Takasaki M. (14-3-3 proteins and zeta isoform containing neurofibrillary tangles in patients with Alzheimer's disease. Acta Neuropathologica 2004, 108:279-286.
-
(2004)
Acta Neuropathologica
, vol.108
, pp. 279-286
-
-
Umahara, T.1
Uchihara, T.2
Tsuchiya, K.3
Nakamura, A.4
Iwamoto, T.5
Ikeda, K.6
Takasaki, M.7
-
177
-
-
56849104094
-
Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins
-
Vale C., Botana L.M. Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins. FASEB Journal 2008, 275:6060-6066.
-
(2008)
FASEB Journal
, vol.275
, pp. 6060-6066
-
-
Vale, C.1
Botana, L.M.2
-
178
-
-
0038702246
-
Phosphatases in apoptosis: to be or not to be, PP2A is in the heart of the question
-
Van Hoof C., Goris J. Phosphatases in apoptosis: to be or not to be, PP2A is in the heart of the question. Biochimica et Biophysica Acta 2003, 1640:97-104.
-
(2003)
Biochimica et Biophysica Acta
, vol.1640
, pp. 97-104
-
-
Van Hoof, C.1
Goris, J.2
-
179
-
-
0033946740
-
Phosphorylation of the PTEN tail regulates protein stability and function
-
Vazquez F., Ramaswamy S., Nakamura N., Sellers W.R. Phosphorylation of the PTEN tail regulates protein stability and function. Molecular and Cellular Biology 2000, 20:5010-5018.
-
(2000)
Molecular and Cellular Biology
, vol.20
, pp. 5010-5018
-
-
Vazquez, F.1
Ramaswamy, S.2
Nakamura, N.3
Sellers, W.R.4
-
180
-
-
23744482703
-
Increase in tau tyrosine phosphorylation correlates with the formation of tau aggregates
-
Vega I.E., Cui L., Propst J.A., Hutton M.L., Lee G., Yen S.H. Increase in tau tyrosine phosphorylation correlates with the formation of tau aggregates. Brain Research Molecular Brain Research 2005, 138:135-144.
-
(2005)
Brain Research Molecular Brain Research
, vol.138
, pp. 135-144
-
-
Vega, I.E.1
Cui, L.2
Propst, J.A.3
Hutton, M.L.4
Lee, G.5
Yen, S.H.6
-
181
-
-
61849092013
-
PP1 inhibition by Abeta peptide as a potential pathological mechanism in Alzheimer's disease
-
Vintem A.P., Henriques A.G., da Cruz E.S.O.A., da Cruz E.S.E.F. PP1 inhibition by Abeta peptide as a potential pathological mechanism in Alzheimer's disease. Neurotoxicology and Teratology 2009, 31:85-88.
-
(2009)
Neurotoxicology and Teratology
, vol.31
, pp. 85-88
-
-
Vintem, A.P.1
Henriques, A.G.2
da Cruz, E.S.O.A.3
da Cruz, E.S.E.F.4
-
182
-
-
61649127812
-
From promiscuity to precision: protein phosphatases get a makeover
-
Virshup D.M., Shenolikar S. From promiscuity to precision: protein phosphatases get a makeover. Molecular Cell 2009, 33:537-545.
-
(2009)
Molecular Cell
, vol.33
, pp. 537-545
-
-
Virshup, D.M.1
Shenolikar, S.2
-
183
-
-
0035075793
-
PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus
-
Vogelsberg-Ragaglia V., Schuck T., Trojanowski J.Q., Lee V.M. PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus. Experimental Neurology 2001, 168:402-412.
-
(2001)
Experimental Neurology
, vol.168
, pp. 402-412
-
-
Vogelsberg-Ragaglia, V.1
Schuck, T.2
Trojanowski, J.Q.3
Lee, V.M.4
-
184
-
-
0030720062
-
Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A
-
Walsh A.H., Cheng A., Honkanen R.E. Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A. FEBS Letters 1997, 416:230-234.
-
(1997)
FEBS Letters
, vol.416
, pp. 230-234
-
-
Walsh, A.H.1
Cheng, A.2
Honkanen, R.E.3
-
185
-
-
68949102230
-
Protein phosphatase 2A regulates self-renewal of Drosophila neural stem cells
-
Wang C., Chang K.C., Somers G., Virshup D., Ang B.T., Tang C., Yu F., Wang H. Protein phosphatase 2A regulates self-renewal of Drosophila neural stem cells. Development 2009, 136:2287-2296.
-
(2009)
Development
, vol.136
, pp. 2287-2296
-
-
Wang, C.1
Chang, K.C.2
Somers, G.3
Virshup, D.4
Ang, B.T.5
Tang, C.6
Yu, F.7
Wang, H.8
-
186
-
-
0028902487
-
Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B
-
Wang J.Z., Gong C.X., Zaidi T., Grundke-Iqbal I., Iqbal K. Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B. Journal of Biological Chemistry 1995, 270:4854-4860.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 4854-4860
-
-
Wang, J.Z.1
Gong, C.X.2
Zaidi, T.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
187
-
-
0029995590
-
Restoration of biological activity of Alzheimer abnormally phosphorylated tau by dephosphorylation with protein phosphatase-2A, -2B and -1
-
Wang J.Z., Grundke-Iqbal I., Iqbal K. Restoration of biological activity of Alzheimer abnormally phosphorylated tau by dephosphorylation with protein phosphatase-2A, -2B and -1. Brain Research Molecular Brain Research 1996, 38:200-208.
-
(1996)
Brain Research Molecular Brain Research
, vol.38
, pp. 200-208
-
-
Wang, J.Z.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
188
-
-
33846212717
-
Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration
-
Wang J.Z., Grundke-Iqbal I., Iqbal K. Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration. European Journal of Neuroscience 2007, 25:59-68.
-
(2007)
European Journal of Neuroscience
, vol.25
, pp. 59-68
-
-
Wang, J.Z.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
189
-
-
78649859760
-
The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment
-
Wang X., Blanchard J., Kohlbrenner E., Clement N., Linden R.M., Radu A., Grundke-Iqbal I., Iqbal K. The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment. FASEB Journal 2010, 24:4420-4432.
-
(2010)
FASEB Journal
, vol.24
, pp. 4420-4432
-
-
Wang, X.1
Blanchard, J.2
Kohlbrenner, E.3
Clement, N.4
Linden, R.M.5
Radu, A.6
Grundke-Iqbal, I.7
Iqbal, K.8
-
190
-
-
33746456956
-
Effects of endogenous beta-amyloid overproduction on tau phosphorylation in cell culture
-
Wang Z.F., Li H.L., Li X.C., Zhang Q., Tian Q., Wang Q., Xu H., Wang J.Z. Effects of endogenous beta-amyloid overproduction on tau phosphorylation in cell culture. Journal of Neurochemistry 2006, 98:1167-1175.
-
(2006)
Journal of Neurochemistry
, vol.98
, pp. 1167-1175
-
-
Wang, Z.F.1
Li, H.L.2
Li, X.C.3
Zhang, Q.4
Tian, Q.5
Wang, Q.6
Xu, H.7
Wang, J.Z.8
-
191
-
-
0035253607
-
PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways
-
Weng L., Brown J., Eng C. PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways. Human Molecular Genetics 2001, 10:237-242.
-
(2001)
Human Molecular Genetics
, vol.10
, pp. 237-242
-
-
Weng, L.1
Brown, J.2
Eng, C.3
-
192
-
-
41549090369
-
Multiple pathways regulated by the tumor suppressor PP2A in transformation
-
Westermarck J., Hahn W.C. Multiple pathways regulated by the tumor suppressor PP2A in transformation. Trends in Molecular Medicine 2008, 14:152-160.
-
(2008)
Trends in Molecular Medicine
, vol.14
, pp. 152-160
-
-
Westermarck, J.1
Hahn, W.C.2
-
193
-
-
0035340295
-
The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase
-
Woods Y.L., Cohen P., Becker W., Jakes R., Goedert M., Wang X., Proud C.G. The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase. Biochemical Journal 2001, 355:609-615.
-
(2001)
Biochemical Journal
, vol.355
, pp. 609-615
-
-
Woods, Y.L.1
Cohen, P.2
Becker, W.3
Jakes, R.4
Goedert, M.5
Wang, X.6
Proud, C.G.7
-
194
-
-
52049100425
-
Structure of a protein phosphatase 2A holoenzyme: insights into B55-mediated Tau dephosphorylation
-
Xu Y., Chen Y., Zhang P., Jeffrey P.D., Shi Y. Structure of a protein phosphatase 2A holoenzyme: insights into B55-mediated Tau dephosphorylation. Molecular Cell 2008, 31:873-885.
-
(2008)
Molecular Cell
, vol.31
, pp. 873-885
-
-
Xu, Y.1
Chen, Y.2
Zhang, P.3
Jeffrey, P.D.4
Shi, Y.5
-
195
-
-
33845404441
-
Structure of the protein phosphatase 2A holoenzyme
-
Xu Y., Xing Y., Chen Y., Chao Y., Lin Z., Fan E., Yu J.W., Strack S., Jeffrey P.D., Shi Y. Structure of the protein phosphatase 2A holoenzyme. Cell 2006, 127:1239-1251.
-
(2006)
Cell
, vol.127
, pp. 1239-1251
-
-
Xu, Y.1
Xing, Y.2
Chen, Y.3
Chao, Y.4
Lin, Z.5
Fan, E.6
Yu, J.W.7
Strack, S.8
Jeffrey, P.D.9
Shi, Y.10
-
196
-
-
0029737421
-
Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II
-
Yamaguchi H., Ishiguro K., Uchida T., Takashima A., Lemere C.A., Imahori K. Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II. Acta Neuropathologica 1996, 92:232-241.
-
(1996)
Acta Neuropathologica
, vol.92
, pp. 232-241
-
-
Yamaguchi, H.1
Ishiguro, K.2
Uchida, T.3
Takashima, A.4
Lemere, C.A.5
Imahori, K.6
-
197
-
-
24144497098
-
Phosphorylation of tau at serine 416 by Ca2+/calmodulin-dependent protein kinase II in neuronal soma in brain
-
Yamamoto H., Hiragami Y., Murayama M., Ishizuka K., Kawahara M., Takashima A. Phosphorylation of tau at serine 416 by Ca2+/calmodulin-dependent protein kinase II in neuronal soma in brain. Journal of Neurochemistry 2005, 94:1438-1447.
-
(2005)
Journal of Neurochemistry
, vol.94
, pp. 1438-1447
-
-
Yamamoto, H.1
Hiragami, Y.2
Murayama, M.3
Ishizuka, K.4
Kawahara, M.5
Takashima, A.6
-
198
-
-
77649269312
-
PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR
-
Yan L., Mieulet V., Burgess D., Findlay G.M., Sully K., Procter J., Goris J., Janssens V., Morrice N.A., Lamb R.F. PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR. Molecular Cell 2010, 37:633-642.
-
(2010)
Molecular Cell
, vol.37
, pp. 633-642
-
-
Yan, L.1
Mieulet, V.2
Burgess, D.3
Findlay, G.M.4
Sully, K.5
Procter, J.6
Goris, J.7
Janssens, V.8
Morrice, N.A.9
Lamb, R.F.10
-
199
-
-
79959736543
-
Glycogen synthase kinase-3beta regulates Tyr307 phosphorylation of protein phosphatase-2A via protein tyrosine phosphatase 1B but not Src
-
Yao X.Q., Zhang X.X., Yin Y.Y., Liu B., Luo D.J., Liu D., Chen N.N., Ni Z.F., Wang X., Wang Q., Wang J.Z., Liu G.P. Glycogen synthase kinase-3beta regulates Tyr307 phosphorylation of protein phosphatase-2A via protein tyrosine phosphatase 1B but not Src. Biochemical Journal 2011, 437:335-344.
-
(2011)
Biochemical Journal
, vol.437
, pp. 335-344
-
-
Yao, X.Q.1
Zhang, X.X.2
Yin, Y.Y.3
Liu, B.4
Luo, D.J.5
Liu, D.6
Chen, N.N.7
Ni, Z.F.8
Wang, X.9
Wang, Q.10
Wang, J.Z.11
Liu, G.P.12
-
200
-
-
0034685703
-
Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain
-
Yasojima K., Kuret J., DeMaggio A.J., McGeer E., McGeer P.L. Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain. Brain Research 2000, 865:116-120.
-
(2000)
Brain Research
, vol.865
, pp. 116-120
-
-
Yasojima, K.1
Kuret, J.2
DeMaggio, A.J.3
McGeer, E.4
McGeer, P.L.5
-
201
-
-
79960739369
-
Upregulation of AKT Attenuates amyloid-beta-induced cell apoptosis
-
Yin G., Li L.Y., Qu M., Luo H.B., Wang J.Z., Zhou X.W. Upregulation of AKT Attenuates amyloid-beta-induced cell apoptosis. Journal of Alzheimer's Disease 2011.
-
(2011)
Journal of Alzheimer's Disease
-
-
Yin, G.1
Li, L.Y.2
Qu, M.3
Luo, H.B.4
Wang, J.Z.5
Zhou, X.W.6
-
202
-
-
77049107343
-
Acetyl-l-carnitine attenuates okadaic acid induced tau hyperphosphorylation and spatial memory impairment in rats
-
Yin Y.Y., Liu H., Cong X.B., Liu Z., Wang Q., Wang J.Z., Zhu L.Q. Acetyl-l-carnitine attenuates okadaic acid induced tau hyperphosphorylation and spatial memory impairment in rats. Journal of Alzheimer's Disease 2010, 19:735-746.
-
(2010)
Journal of Alzheimer's Disease
, vol.19
, pp. 735-746
-
-
Yin, Y.Y.1
Liu, H.2
Cong, X.B.3
Liu, Z.4
Wang, Q.5
Wang, J.Z.6
Zhu, L.Q.7
-
203
-
-
57049094384
-
Okadaic acid increases autophagosomes in rat neurons: implications for Alzheimer's disease
-
Yoon S.Y., Choi J.E., Kweon H.S., Choe H., Kim S.W., Hwang O., Lee H., Lee J.Y., Kim D.H. Okadaic acid increases autophagosomes in rat neurons: implications for Alzheimer's disease. Journal of Neuroscience Research 2008, 86:3230-3239.
-
(2008)
Journal of Neuroscience Research
, vol.86
, pp. 3230-3239
-
-
Yoon, S.Y.1
Choi, J.E.2
Kweon, H.S.3
Choe, H.4
Kim, S.W.5
Hwang, O.6
Lee, H.7
Lee, J.Y.8
Kim, D.H.9
-
204
-
-
0345096631
-
Phosphorylation of tau protein to sites found in Alzheimer's disease brain is catalyzed by Ca2+/calmodulin-dependent protein kinase II as demonstrated tandem mass spectrometry
-
Yoshimura Y., Ichinose T., Yamauchi T. Phosphorylation of tau protein to sites found in Alzheimer's disease brain is catalyzed by Ca2+/calmodulin-dependent protein kinase II as demonstrated tandem mass spectrometry. Neuroscience Letters 2003, 353:185-188.
-
(2003)
Neuroscience Letters
, vol.353
, pp. 185-188
-
-
Yoshimura, Y.1
Ichinose, T.2
Yamauchi, T.3
-
205
-
-
0035177048
-
Methylation of the protein phosphatase 2A catalytic subunit is essential for association of Balpha regulatory subunit but not SG2NA, striatin, or polyomavirus middle tumor antigen
-
Yu X.X., Du X., Moreno C.S., Green R.E., Ogris E., Feng Q., Chou L., McQuoid M.J., Pallas D.C. Methylation of the protein phosphatase 2A catalytic subunit is essential for association of Balpha regulatory subunit but not SG2NA, striatin, or polyomavirus middle tumor antigen. Molecular Biology of the Cell 2001, 12:185-199.
-
(2001)
Molecular Biology of the Cell
, vol.12
, pp. 185-199
-
-
Yu, X.X.1
Du, X.2
Moreno, C.S.3
Green, R.E.4
Ogris, E.5
Feng, Q.6
Chou, L.7
McQuoid, M.J.8
Pallas, D.C.9
-
206
-
-
84856721541
-
Calyculin A reveals serine/threonine phosphatase protein phosphatase 1 as a regulatory nodal point in canonical signal transducer and activator of transcription 3 signaling of human microvascular endothelial cells
-
Zgheib C., Zouein F.A., Chidiac R., Kurdi M., Booz G.W. Calyculin A reveals serine/threonine phosphatase protein phosphatase 1 as a regulatory nodal point in canonical signal transducer and activator of transcription 3 signaling of human microvascular endothelial cells. Journal of Interferon and Cytokine Research 2012.
-
(2012)
Journal of Interferon and Cytokine Research
-
-
Zgheib, C.1
Zouein, F.A.2
Chidiac, R.3
Kurdi, M.4
Booz, G.W.5
-
207
-
-
51649119364
-
Homocysteine induces tau phosphorylation by inactivating protein phosphatase 2A in rat hippocampus
-
Zhang C.E., Tian Q., Wei W., Peng J.H., Liu G.P., Zhou X.W., Wang Q., Wang D.W., Wang J.Z. Homocysteine induces tau phosphorylation by inactivating protein phosphatase 2A in rat hippocampus. Neurobiology of Aging 2008, 29:1654-1665.
-
(2008)
Neurobiology of Aging
, vol.29
, pp. 1654-1665
-
-
Zhang, C.E.1
Tian, Q.2
Wei, W.3
Peng, J.H.4
Liu, G.P.5
Zhou, X.W.6
Wang, Q.7
Wang, D.W.8
Wang, J.Z.9
-
208
-
-
33845619414
-
Tumor-suppressor PTEN affects tau phosphorylation, aggregation, and binding to microtubules
-
Zhang X., Li F., Bulloj A., Zhang Y.W., Tong G., Zhang Z., Liao F.F., Xu H. Tumor-suppressor PTEN affects tau phosphorylation, aggregation, and binding to microtubules. FASEB Journal 2006, 20:1272-1274.
-
(2006)
FASEB Journal
, vol.20
, pp. 1272-1274
-
-
Zhang, X.1
Li, F.2
Bulloj, A.3
Zhang, Y.W.4
Tong, G.5
Zhang, Z.6
Liao, F.F.7
Xu, H.8
-
209
-
-
8744271485
-
Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade
-
Zhou G., Golden T., Aragon I.V., Honkanen R.E. Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade. Journal of Biological Chemistry 2004, 279:46595-46605.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 46595-46605
-
-
Zhou, G.1
Golden, T.2
Aragon, I.V.3
Honkanen, R.E.4
-
210
-
-
49349110718
-
Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A
-
Zhou X.W., Gustafsson J.A., Tanila H., Bjorkdahl C., Liu R., Winblad B., Pei J.J. Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A. Neurobiology of Disease 2008, 31:386-394.
-
(2008)
Neurobiology of Disease
, vol.31
, pp. 386-394
-
-
Zhou, X.W.1
Gustafsson, J.A.2
Tanila, H.3
Bjorkdahl, C.4
Liu, R.5
Winblad, B.6
Pei, J.J.7
-
211
-
-
68949154348
-
Interactions between glycogen synthase kinase 3beta, protein kinase B, and protein phosphatase 2A in tau phosphorylation in mouse N2a neuroblastoma cells
-
Zhou X.W., Winblad B., Guan Z., Pei J.J. Interactions between glycogen synthase kinase 3beta, protein kinase B, and protein phosphatase 2A in tau phosphorylation in mouse N2a neuroblastoma cells. Journal of Alzheimer's Disease 2009.
-
(2009)
Journal of Alzheimer's Disease
-
-
Zhou, X.W.1
Winblad, B.2
Guan, Z.3
Pei, J.J.4
-
212
-
-
77949393847
-
Protein phosphatase 2A facilitates axonogenesis by dephosphorylating CRMP2
-
Zhu L.Q., Zheng H.Y., Peng C.X., Liu D., Li H.L., Wang Q., Wang J.Z. Protein phosphatase 2A facilitates axonogenesis by dephosphorylating CRMP2. Journal of Neuroscience 2010, 30:3839-3848.
-
(2010)
Journal of Neuroscience
, vol.30
, pp. 3839-3848
-
-
Zhu, L.Q.1
Zheng, H.Y.2
Peng, C.X.3
Liu, D.4
Li, H.L.5
Wang, Q.6
Wang, J.Z.7
-
213
-
-
0035142804
-
Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
-
Zhu X., Raina A.K., Rottkamp C.A., Aliev G., Perry G., Boux H., Smith M.A. Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. Journal of Neurochemistry 2001, 76:435-441.
-
(2001)
Journal of Neurochemistry
, vol.76
, pp. 435-441
-
-
Zhu, X.1
Raina, A.K.2
Rottkamp, C.A.3
Aliev, G.4
Perry, G.5
Boux, H.6
Smith, M.A.7
-
214
-
-
0033782845
-
Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease
-
Zhu X., Rottkamp C.A., Boux H., Takeda A., Perry G., Smith M.A. Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. Journal of Neuropathology and Experimental Neurology 2000, 59:880-888.
-
(2000)
Journal of Neuropathology and Experimental Neurology
, vol.59
, pp. 880-888
-
-
Zhu, X.1
Rottkamp, C.A.2
Boux, H.3
Takeda, A.4
Perry, G.5
Smith, M.A.6
|