Accumulation of tumor-suppressor PTEN in Alzheimer neurofibrillary tangles

Neuroscience Letters

Volumn 471, Issue 1, 2010, Pages 20-24

  Sonoda, Yuma ^a   Mukai, Hideyuki ^a   Matsuo, Kazuhiko ^a   Takahashi, Mikiko ^a   Ono, Yoshitaka ^a   Maeda, Kiyoshi ^b   Akiyama, Haruhiko ^c   Kawamata, Toshio ^a  

^a KOBE UNIVERSITY   (Japan)

^b Faculty of Science   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Alzheimer's disease; Neurofibrillary tangles; Phosphatase; PI3K; PTEN; Tau

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TAU PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; BIOACCUMULATION; CELL LABELING; CELL NUCLEUS; CLINICAL ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; ENTORHINAL CORTEX; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; MALE; NEUROFIBRILLARY TANGLE; NEUROFILAMENT; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; SENILE PLAQUE; SIGNAL TRANSDUCTION; SUBICULUM; TUMOR SUPPRESSOR GENE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ASTROCYTES; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; MALE; MIDDLE AGED; NEUROFIBRILLARY TANGLES; NEURONS; PHOSPHORYLATION; PROTEIN TRANSPORT; PTEN PHOSPHOHYDROLASE; TAU PROTEINS;

EID: 75749112450     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.12.078     Document Type: Article

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