Folate deficiency induces in vitro and mouse brain region-specific downregulation of leucine carboxyl methyltransferase-1 and protein phosphatase 2A Bα subunit expression that correlate with enhanced tau phosphorylation

Journal of Neuroscience

Volumn 28, Issue 45, 2008, Pages 11477-11487

  Sontag, Jean Marie ^a   Nunbhakdi Craig, Viyada ^a   Montgomery, Lisa ^a   Arning, Erland ^b   Bottiglieri, Teodoro ^b   Sontag, Estelle ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Folate; Methylation; Methylesterase; Methyltransferase; PP2A; Tau

Indexed keywords

LEUCINE CARBOXYLMETHYLTRANSFERASE 1; METHYLTRANSFERASE; PHOSPHOPROTEIN PHOSPHATASE 2A; TAU PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ANALYSIS; FOLIC ACID DEFICIENCY; IN VITRO STUDY; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METHYLATION; PROTEIN PHOSPHORYLATION;

ANIMALS; BRAIN; CARBOXYLIC ESTER HYDROLASES; CELL DEATH; CELL LINE, TRANSFORMED; DOWN-REGULATION; FOLIC ACID DEFICIENCY; MALE; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PROTEIN O-METHYLTRANSFERASE; PROTEIN PHOSPHATASE 2; SERINE; TAU PROTEINS;

EID: 58149213742     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2816-08.2008     Document Type: Article

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