Substrate-specific reduction of PP2A activity exaggerates tau pathology

Biochemical and Biophysical Research Communications

Volumn 379, Issue 2, 2009, Pages 400-405

  Deters, Natasha ^a   Ittner, Lars M ^a   Götz, Jürgen ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Alzheimer's disease (AD); Frontotemporal dementia (FTD); Kinase; Microtubule; Neurofibrillary tangle (NFT); Phosphatase; Tau

Indexed keywords

MUTANT PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN PHOSPHATASE 2A L309A CALPHA; TAU PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; FEMALE; GENETIC CROSS; HIPPOCAMPUS; MICROTUBULE ASSEMBLY; MOUSE; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TAUOPATHY; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; ANIMALS; BRAIN; HUMANS; MICE; MICE, TRANSGENIC; MUTATION; NEUROFIBRILLARY TANGLES; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; PROTEIN SUBUNITS; SOLUBILITY; SUBSTRATE SPECIFICITY; TAU PROTEINS;

MUS;

EID: 58149526301     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.12.140     Document Type: Article

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