Homocysteine-induced acute excitotoxicity in cerebellar granule cells in vitro is accompanied by PP2A-mediated dephosphorylation of tau

Neurochemistry International

Volumn 55, Issue 1-3, 2009, Pages 174-180

  Kuszczyk, Magdalena ^a   Gordon Krajcer, Wanda ^a   Lazarewicz, Jerzy W ^a  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Cerebellar granule cells; Excitotoxicity; Homocysteine; mGluRs; NMDA receptors; Phosphorylation; PP2A; Tau protein

Indexed keywords

4 CARBOXY 2 METHYLPHENYLGLYCINE; DIZOCILPINE; HOMOCYSTEINE; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 5; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; EXCITOTOXICITY; GRANULE CELL; HYPERHOMOCYSTEINEMIA; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; ENZYME INHIBITORS; EXCITATORY AMINO ACIDS; HOMOCYSTEINE; IMMUNOHISTOCHEMISTRY; PHENOTYPE; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; TAU PROTEINS;

RATTUS;

EID: 64949088215     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2009.02.010     Document Type: Article

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