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Volumn 120, Issue 1, 2012, Pages 157-164

Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling

Author keywords

Akt; Alzheimer disease; GSK 3beta; neuroglobin; tau hyperphosphorylation

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; NEUROGLOBIN; PROTEIN KINASE B; TAU PROTEIN;

EID: 83855162924     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07275.x     Document Type: Article
Times cited : (64)

References (37)
  • 1
    • 77954773829 scopus 로고    scopus 로고
    • Neuroglobin overexpression in cultured human neuronal cells protects against hydrogen peroxide insult via activating phosphoinositide-3 kinase and opening the mitochondrial K(ATP) channel
    • Antao S. T., Duong T. T., Aran R., and, Witting P. K., (2010) Neuroglobin overexpression in cultured human neuronal cells protects against hydrogen peroxide insult via activating phosphoinositide-3 kinase and opening the mitochondrial K(ATP) channel. Antioxid. Redox Signal. 13, 769-781.
    • (2010) Antioxid. Redox Signal. , vol.13 , pp. 769-781
    • Antao, S.T.1    Duong, T.T.2    Aran, R.3    Witting, P.K.4
  • 4
    • 0034726874 scopus 로고    scopus 로고
    • A vertebrate globin expressed in the brain
    • Burmester T., Weich B., Reinhardt S., and, Hankeln T., (2000) A vertebrate globin expressed in the brain. Nature 407, 520-523.
    • (2000) Nature , vol.407 , pp. 520-523
    • Burmester, T.1    Weich, B.2    Reinhardt, S.3    Hankeln, T.4
  • 5
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • DOI 10.1038/378785a0
    • Cross D. A., Alessi D. R., Cohen P., Andjelkovich M., and, Hemmings B. A., (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378, 785-789. (Pubitemid 26004411)
    • (1995) Nature , vol.378 , Issue.6559 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 6
    • 59449107434 scopus 로고    scopus 로고
    • Multiple protective activities of neuroglobin in cultured neuronal cells exposed to hypoxia re-oxygenation injury
    • Duong T. T., Witting P. K., Antao S. T., Parry S. N., Kennerson M., Lai B., Vogt S., Lay P. A., and, Harris H. H., (2009) Multiple protective activities of neuroglobin in cultured neuronal cells exposed to hypoxia re-oxygenation injury. J. Neurochem. 108, 1143-1154.
    • (2009) J. Neurochem. , vol.108 , pp. 1143-1154
    • Duong, T.T.1    Witting, P.K.2    Antao, S.T.3    Parry, S.N.4    Kennerson, M.5    Lai, B.6    Vogt, S.7    Lay, P.A.8    Harris, H.H.9
  • 7
    • 33750705253 scopus 로고    scopus 로고
    • Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death
    • DOI 10.1016/j.neulet.2006.09.027, PII S030439400600975X
    • Fordel E., Thijs L., Martinet W., Lenjou M., Laufs T., Van Bockstaele D., Moens L., and, Dewilde S., (2006) Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death. Neurosci. Lett. 410, 146-151. (Pubitemid 44709414)
    • (2006) Neuroscience Letters , vol.410 , Issue.2 , pp. 146-151
    • Fordel, E.1    Thijs, L.2    Martinet, W.3    Lenjou, M.4    Laufs, T.5    Van Bockstaele, D.6    Moens, L.7    Dewilde, S.8
  • 8
    • 38649090098 scopus 로고    scopus 로고
    • Neuroglobin: an endogenous neuroprotectant
    • DOI 10.1016/j.coph.2007.09.003, PII S1471489207001592
    • Greenberg D. A., Jin K., and, Khan A. A., (2008) Neuroglobin: an endogenous neuroprotectant. Curr. Opin. Pharmacol. 8, 20-24. (Pubitemid 351168689)
    • (2008) Current Opinion in Pharmacology , vol.8 , Issue.1 , pp. 20-24
    • Greenberg, D.A.1    Jin, K.2    Khan, A.A.3
  • 9
    • 0022550260 scopus 로고
    • Defective brain microtubule assembly in Alzheimer's disease
    • Iqbal K., Grundke-Iqbal I., Zaidi T., Merz P. A., Wen G. Y., Shaikh S. S., Wisniewski H. M., Alafuzoff I., and, Winblad B., (1986) Defective brain microtubule assembly in Alzheimer's disease. Lancet 2, 421-426. (Pubitemid 16047953)
    • (1986) Lancet , vol.2 , Issue.8504 , pp. 421-426
    • Iqbal, K.1    Grundke-Iqbal, I.2    Zaidi, T.3
  • 10
    • 33749472634 scopus 로고    scopus 로고
    • Role of p53 up-regulated modulator of apoptosis and phosphorylated Akt in melanoma cell growth, apoptosis, and patient survival
    • DOI 10.1158/0008-5472.CAN-05-3633
    • Karst A. M., Dai D. L., Cheng J. Q., and, Li G., (2006) Role of p53 up-regulated modulator of apoptosis and phosphorylated Akt in melanoma cell growth, apoptosis, and patient survival. Cancer Res. 66, 9221-9226. (Pubitemid 44521143)
    • (2006) Cancer Research , vol.66 , Issue.18 , pp. 9221-9226
    • Karst, A.M.1    Dai, D.L.2    Cheng, J.Q.3    Li, G.4
  • 11
    • 55749098112 scopus 로고    scopus 로고
    • Neuroglobin: Endogenous neuroprotectant or maintenance of homeostasis?
    • author reply e179
    • Kelsen J., Hundahl C. A., and, Hay-Schmidt A., (2008) Neuroglobin: endogenous neuroprotectant or maintenance of homeostasis? Stroke 39, e177-e178; author reply e179.
    • (2008) Stroke , vol.39
    • Kelsen, J.1    Hundahl, C.A.2    Hay-Schmidt, A.3
  • 13
    • 37649003389 scopus 로고    scopus 로고
    • Neuroglobin attenuates beta-amyloid neurotoxicity in vitro and transgenic Alzheimer phenotype in vivo
    • Khan A. A., Mao X. O., Banwait S., Jin K., and, Greenberg D. A., (2007a) Neuroglobin attenuates beta-amyloid neurotoxicity in vitro and transgenic Alzheimer phenotype in vivo. Proc. Natl. Acad. Sci. USA 104, 19114-19119.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 19114-19119
    • Khan, A.A.1    Mao, X.O.2    Banwait, S.3    Jin, K.4    Greenberg, D.A.5
  • 14
    • 34447516984 scopus 로고    scopus 로고
    • A neuroglobin-overexpressing transgenic mouse
    • DOI 10.1016/j.gene.2007.02.044, PII S0378111907002041
    • Khan A. A., Sun Y., Jin K., Mao X. O., Chen S., Ellerby L. M., and, Greenberg D. A., (2007b) A neuroglobin-overexpressing transgenic mouse. Gene 398, 172-176. (Pubitemid 47068890)
    • (2007) Gene , vol.398 , Issue.SPEC. ISS. 1-2 , pp. 172-176
    • Khan, A.A.1    Sun, Y.2    Jin, K.3    Mao, X.O.4    Chen, S.5    Ellerby, L.M.6    Greenberg, D.A.7
  • 15
    • 0025110182 scopus 로고
    • β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage
    • DOI 10.1016/0006-8993(90)91355-K
    • Koh J. Y., Yang L. L., and, Cotman C. W., (1990) Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res. 533, 315-320. (Pubitemid 20377714)
    • (1990) Brain Research , vol.533 , Issue.2 , pp. 315-320
    • Koh, J.-Y.1    Yang, L.L.2    Cotman, C.W.3
  • 17
    • 53649088015 scopus 로고    scopus 로고
    • Neuroglobin protects PC12 cells against beta-amyloid-induced cell injury
    • Li R. C., Pouranfar F., Lee S. K., Morris M. W., Wang Y., and, Gozal D., (2008b) Neuroglobin protects PC12 cells against beta-amyloid-induced cell injury. Neurobiol. Aging 29, 1815-1822.
    • (2008) Neurobiol. Aging , vol.29 , pp. 1815-1822
    • Li, R.C.1    Pouranfar, F.2    Lee, S.K.3    Morris, M.W.4    Wang, Y.5    Gozal, D.6
  • 18
    • 78049458153 scopus 로고    scopus 로고
    • Neuroglobin protects neurons against oxidative stress in global ischemia
    • Li R. C., Guo S. Z., Lee S. K., and, Gozal D., (2010) Neuroglobin protects neurons against oxidative stress in global ischemia. J. Cereb. Blood Flow Metab. 30, 1874-1882.
    • (2010) J. Cereb. Blood Flow Metab. , vol.30 , pp. 1874-1882
    • Li, R.C.1    Guo, S.Z.2    Lee, S.K.3    Gozal, D.4
  • 19
    • 78649783156 scopus 로고    scopus 로고
    • The activity of recombinant human neuroglobin as an antioxidant and free radical scavenger
    • Li W., Wu Y., Ren C., Lu Y., Gao Y., Zheng X., and, Zhang C., (2011) The activity of recombinant human neuroglobin as an antioxidant and free radical scavenger. Proteins 79, 115-125.
    • (2011) Proteins , vol.79 , pp. 115-125
    • Li, W.1    Wu, Y.2    Ren, C.3    Lu, Y.4    Gao, Y.5    Zheng, X.6    Zhang, C.7
  • 20
    • 0346434153 scopus 로고    scopus 로고
    • Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory
    • Liu S. J., Zhang A. H., Li H. L., Wang Q., Deng H. M., Netzer W. J., Xu H., and, Wang J. Z., (2003) Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory. J. Neurochem. 87, 1333-1344. (Pubitemid 38020568)
    • (2003) Journal of Neurochemistry , vol.87 , Issue.6 , pp. 1333-1344
    • Liu, S.J.1    Zhang, A.H.2    Li, H.L.3    Wang, Q.4    Deng, H.M.5    Netzer, W.J.6    Xu, H.7    Wang, J.Z.8
  • 21
    • 77951666767 scopus 로고    scopus 로고
    • Neuroglobin protects nerve cells from apoptosis by inhibiting the intrinsic pathway of cell death
    • Raychaudhuri S., Skommer J., Henty K., Birch N., and, Brittain T., (2010) Neuroglobin protects nerve cells from apoptosis by inhibiting the intrinsic pathway of cell death. Apoptosis 15, 401-411.
    • (2010) Apoptosis , vol.15 , pp. 401-411
    • Raychaudhuri, S.1    Skommer, J.2    Henty, K.3    Birch, N.4    Brittain, T.5
  • 23
    • 0035489468 scopus 로고    scopus 로고
    • PKB/AKT: Functional insights from genetic models
    • DOI 10.1038/35096067
    • Scheid M. P., and, Woodgett J. R., (2001) PKB/AKT: functional insights from genetic models. Nat. Rev. Mol. Cell Biol. 2, 760-768. (Pubitemid 33679838)
    • (2001) Nature Reviews Molecular Cell Biology , vol.2 , Issue.10 , pp. 760-768
    • Scheid, M.P.1    Woodgett, J.R.2
  • 25
    • 44949226185 scopus 로고    scopus 로고
    • 17beta-estradiol attenuates glycogen synthase kinase-3beta activation and tau hyperphosphorylation in Akt-independent manner
    • Shi H. R., Zhu L. Q., Wang S. H., Liu X. A., Tian Q., Zhang Q., Wang Q., and, Wang J. Z., (2008) 17beta-estradiol attenuates glycogen synthase kinase-3beta activation and tau hyperphosphorylation in Akt-independent manner. J. Neural Transm. 115, 879-888.
    • (2008) J. Neural Transm. , vol.115 , pp. 879-888
    • Shi, H.R.1    Zhu, L.Q.2    Wang, S.H.3    Liu, X.A.4    Tian, Q.5    Zhang, Q.6    Wang, Q.7    Wang, J.Z.8
  • 27
    • 0037087220 scopus 로고    scopus 로고
    • Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
    • DOI 10.1016/S0304-3940(01)02583-6, PII S0304394001025836
    • Sun X., Sato S., Murayama O., Murayama M., Park J. M., Yamaguchi H., and, Takashima A., (2002) Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100. Neurosci. Lett. 321, 61-64. (Pubitemid 34185499)
    • (2002) Neuroscience Letters , vol.321 , Issue.1-2 , pp. 61-64
    • Sun, X.1    Sato, S.2    Murayama, O.3    Murayama, M.4    Park, J.-M.5    Yamaguchi, H.6    Takashima, A.7
  • 30
    • 77956915887 scopus 로고    scopus 로고
    • Neuroglobin and Alzheimer's dementia: Genetic association and gene expression changes
    • Szymanski M., Wang R., Fallin M. D., Bassett S. S., and, Avramopoulos D., (2010) Neuroglobin and Alzheimer's dementia: genetic association and gene expression changes. Neurobiol. Aging 31, 1835-1842.
    • (2010) Neurobiol. Aging , vol.31 , pp. 1835-1842
    • Szymanski, M.1    Wang, R.2    Fallin, M.D.3    Bassett, S.S.4    Avramopoulos, D.5
  • 31
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-AKT pathway in human cancer
    • Vivanco I., and, Sawyers C. L., (2002) The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev. Cancer 2, 489-501. (Pubitemid 37328931)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 32
    • 33846212717 scopus 로고    scopus 로고
    • Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration
    • DOI 10.1111/j.1460-9568.2006.05226.x
    • Wang J. Z., Grundke-Iqbal I., and, Iqbal K., (2007) Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration. Eur. J. Neurosci. 25, 59-68. (Pubitemid 46098893)
    • (2007) European Journal of Neuroscience , vol.25 , Issue.1 , pp. 59-68
    • Wang, J.-Z.1    Grundke-Iqbal, I.2    Iqbal, K.3
  • 35
    • 67649484358 scopus 로고    scopus 로고
    • Neuroglobin-overexpression alters hypoxic response gene expression in primary neuron culture following oxygen glucose deprivation
    • Yu Z., Liu J., Guo S., Xing C., Fan X., Ning M., Yuan J. C., Lo E. H., and, Wang X., (2009) Neuroglobin-overexpression alters hypoxic response gene expression in primary neuron culture following oxygen glucose deprivation. Neuroscience 162, 396-403.
    • (2009) Neuroscience , vol.162 , pp. 396-403
    • Yu, Z.1    Liu, J.2    Guo, S.3    Xing, C.4    Fan, X.5    Ning, M.6    Yuan, J.C.7    Lo, E.H.8    Wang, X.9
  • 36
    • 36048937547 scopus 로고    scopus 로고
    • Activation of glycogen synthase kinase-3 inhibits long-term potentiation with synapse-associated impairments
    • DOI 10.1523/JNEUROSCI.3321-07.2007
    • Zhu L. Q., Wang S. H., Liu D., Yin Y. Y., Tian Q., Wang X. C., Wang Q., Chen J. G., and, Wang J. Z., (2007) Activation of glycogen synthase kinase-3 inhibits long-term potentiation with synapse-associated impairments. J. Neurosci. 27, 12211-12220. (Pubitemid 350085482)
    • (2007) Journal of Neuroscience , vol.27 , Issue.45 , pp. 12211-12220
    • Zhu, L.-Q.1    Wang, S.-H.2    Liu, D.3    Yin, Y.-Y.4    Tian, Q.5    Wang, X.-C.6    Wang, Q.7    Chen, J.-G.8    Wang, J.-Z.9
  • 37
    • 77949381494 scopus 로고    scopus 로고
    • GSK-3 beta inhibits presynaptic vesicle exocytosis by phosphorylating P/Q-type calcium channel and interrupting SNARE complex formation
    • Zhu L. Q., Liu D., Hu J., Cheng J., Wang S. H., Wang Q., Wang F., Chen J. G., and, Wang J. Z., (2010) GSK-3 beta inhibits presynaptic vesicle exocytosis by phosphorylating P/Q-type calcium channel and interrupting SNARE complex formation. J. Neurosci. 30, 3624-3633.
    • (2010) J. Neurosci. , vol.30 , pp. 3624-3633
    • Zhu, L.Q.1    Liu, D.2    Hu, J.3    Cheng, J.4    Wang, S.H.5    Wang, Q.6    Wang, F.7    Chen, J.G.8    Wang, J.Z.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.