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Volumn 53, Issue 1-3, 2012, Pages 213-228

Cross-roads in the lung: Immune cells and tissue interactions as determinants of allergic asthma

Author keywords

Allergic asthma; Allergic sensitization; Chronic asthma; Immune tolerance; Lung remodeling

Indexed keywords

IMMUNOGLOBULIN E;

EID: 84866740490     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-012-8296-4     Document Type: Article
Times cited : (10)

References (199)
  • 1
    • 79951796396 scopus 로고    scopus 로고
    • The lung: The natural boundary between nature and nurture
    • Seibold MA, SchwartzDA. The lung: the natural boundary between nature and nurture. Annu Rev Physiol. 2011;17(73):457-78.
    • (2011) Annu Rev Physiol. , vol.17 , Issue.73 , pp. 457-478
    • Seibold, M.A.1    Schwartz, D.A.2
  • 3
    • 40049085088 scopus 로고    scopus 로고
    • Natural history of asthma: Persistence versus progression-does the beginning predict the end?
    • Panettieri RA Jr, Covar R, Grant E, Hillyer EV, Bacharier L. Natural history of asthma: persistence versus progression-does the beginning predict the end? J Allergy Clin Immunol. 2008;121(3):607-13.
    • (2008) J Allergy Clin Immunol. , vol.121 , Issue.3 , pp. 607-613
    • Panettieri Jr., R.A.1    Covar, R.2    Grant, E.3    Hillyer, E.V.4    Bacharier, L.5
  • 4
    • 78049309522 scopus 로고    scopus 로고
    • Mechanisms of tolerance and allergic sensitization in the airways and the lungs
    • Curotto de Lafaille MA, Lafaille JJ, Graca L. Mechanisms of tolerance and allergic sensitization in the airways and the lungs. Curr Opin Immunol. 2010;22(5):616-22.
    • (2010) Curr Opin Immunol. , vol.22 , Issue.5 , pp. 616-622
    • Curotto De Lafaille, M.A.1    Lafaille, J.J.2    Graca, L.3
  • 5
    • 65549123867 scopus 로고    scopus 로고
    • Natural and adaptive foxp3? regulatory T cells: More of the same or a division of labor?
    • Curotto de Lafaille MA, Lafaille JJ. Natural and adaptive foxp3? regulatory T cells: more of the same or a division of labor? Immunity 2009;30(5):626-35.
    • (2009) Immunity , vol.30 , Issue.5 , pp. 626-635
    • Curotto De Lafaille, M.A.1    Lafaille, J.J.2
  • 6
    • 79953756066 scopus 로고    scopus 로고
    • Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses
    • Hammad H, Lambrecht BN. Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses. Allergy. 2011;66(5):579-87.
    • (2011) Allergy. , vol.66 , Issue.5 , pp. 579-587
    • Hammad, H.1    Lambrecht, B.N.2
  • 7
    • 79959369140 scopus 로고    scopus 로고
    • The sentinel role of the airway epithelium in asthma pathogenesis
    • Holgate ST. The sentinel role of the airway epithelium in asthma pathogenesis. Immunol Rev. 2011;242(1):205-19.
    • (2011) Immunol Rev. , vol.24 , Issue.1 , pp. 205-219
    • Holgate, S.T.1
  • 8
    • 84880126395 scopus 로고    scopus 로고
    • Host defense and the airway epithelium: Frontline responses that protect against bacterial invasion and pneumonia
    • Eisele NA. Host defense and the airway epithelium: frontline responses that protect against bacterial invasion and pneumonia. J Pathogens 2011;2011.
    • (2011) J Pathogens , pp. 2011
    • Eisele, N.A.1
  • 11
    • 49449112792 scopus 로고    scopus 로고
    • Hierarchical organization of lung progenitor cells: Is there an adult lung tissue stem cell?
    • Stripp BR. Hierarchical organization of lung progenitor cells: is there an adult lung tissue stem cell? Proc Am Thorac Soc. 2008;5(6):695-8.
    • (2008) Proc Am Thorac Soc. , vol.5 , Issue.6 , pp. 695-698
    • Stripp, B.R.1
  • 12
    • 0027032706 scopus 로고
    • The role of the nonciliated bronchiolar epithelial (Clara) cell as the progenitor cell during bronchiolar epithelial differentiation in the perinatal rabbit lung
    • Plopper CG, Nishio SJ, Alley JL, Kass P, Hyde DM. The role of the nonciliated bronchiolar epithelial (Clara) cell as the progenitor cell during bronchiolar epithelial differentiation in the perinatal rabbit lung. Am J Respir Cell Mol Biol. 1992;7(6):606-13.
    • (1992) Am J Respir Cell Mol Biol. , vol.7 , Issue.6 , pp. 606-613
    • Plopper, C.G.1    Nishio, S.J.2    Alley, J.L.3    Kass, P.4    Hyde, D.M.5
  • 13
    • 0033875885 scopus 로고    scopus 로고
    • Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration
    • Reynolds SD, Giangreco A, Power JHT, Stripp BR. Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration. Am J Pathol. 2000;156(1):269-78.
    • (2000) Am J Pathol. , vol.156 , Issue.1 , pp. 269-278
    • Reynolds, S.D.1    Giangreco, A.2    Power, J.H.T.3    Stripp, B.R.4
  • 14
    • 0036314791 scopus 로고    scopus 로고
    • Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction
    • Giangreco A, Reynolds SD, Stripp BR. Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction.AmJ Pathol. 2002;161(1):173-82.
    • (2002) Am J Pathol. , vol.161 , Issue.1 , pp. 173-182
    • Giangreco, A.1    Reynolds, S.D.2    Stripp, B.R.3
  • 16
    • 80051626877 scopus 로고    scopus 로고
    • Innate immunity in the respiratory epithelium
    • Parker D, Prince A. Innate immunity in the respiratory epithelium. Am J Respir Cell Mol Biol. 2011;45(2):189-201.
    • (2011) Am J Respir Cell Mol Biol. , vol.45 , Issue.2 , pp. 189-201
    • Parker, D.1    Prince, A.2
  • 17
    • 79959345632 scopus 로고    scopus 로고
    • Epithelial cells and airway diseases
    • Proud D, Leigh R. Epithelial cells and airway diseases. Immunol Rev. 2011;242(1):186-204.
    • (2011) Immunol Rev. , vol.24 , Issue.1 , pp. 186-204
    • Proud, D.1    Leigh, R.2
  • 18
    • 55149113944 scopus 로고    scopus 로고
    • Welcome to the neighborhood: Epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites
    • Saenz SA, Taylor BC, Artis D. Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev. 2008;226: 172-90.
    • (2008) Immunol Rev. , vol.226 , pp. 172-190
    • Saenz, S.A.1    Taylor, B.C.2    Artis, D.3
  • 19
    • 75549087056 scopus 로고    scopus 로고
    • Disease-associated functions of IL-33: The new kid in the IL-1 family
    • Liew FY, Pitman NI, McInnes IB. Disease-associated functions of IL-33: the new kid in the IL-1 family. Nat Rev Immunol. 2010;10(2):103-10.
    • (2010) Nat Rev Immunol. , vol.10 , Issue.2 , pp. 103-110
    • Liew, F.Y.1    Pitman, N.I.2    McInnes, I.B.3
  • 20
    • 60449084238 scopus 로고    scopus 로고
    • TSLP in epithelial cell and dendritic cell cross talk
    • Liu YJ. TSLP in epithelial cell and dendritic cell cross talk. Adv Immunol. 2009;101:1-25.
    • (2009) Adv Immunol. , vol.101 , pp. 1-25
    • Liu, Y.J.1
  • 21
    • 75749149721 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin
    • He R, Geha RS. Thymic stromal lymphopoietin. Ann N Y Acad Sci. 2010;1183:13-24.
    • (2010) Ann N y Acad Sci. , vol.1183 , pp. 13-24
    • He, R.1    Geha, R.S.2
  • 22
    • 0033826756 scopus 로고    scopus 로고
    • Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma
    • Holgate ST, Lackie P, Wilson S, Roche W, Davies D. Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma. Am J Respir Crit Care Med. 2000;162(3 Pt 2):S113-7.
    • (2000) Am J Respir Crit Care Med. , vol.162 , Issue.3 PART 2
    • Holgate, S.T.1    Lackie, P.2    Wilson, S.3    Roche, W.4    Davies, D.5
  • 23
    • 77249092615 scopus 로고    scopus 로고
    • New insights into innate immune mechanisms underlying allergenicity
    • Wills-Karp M, Nathan A, Page K, Karp CL. New insights into innate immune mechanisms underlying allergenicity. Mucosal Immunol. 2010;3(2):104-10.
    • (2010) Mucosal Immunol. , vol.3 , Issue.2 , pp. 104-110
    • Wills-Karp, M.1    Nathan, A.2    Page, K.3    Karp, C.L.4
  • 24
    • 64149087970 scopus 로고    scopus 로고
    • House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
    • Hammad H, Chieppa M, Perros F, Willart MA, Germain RN, Lambrecht BN. House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat Med. 2009;15(4):410-6.
    • (2009) Nat Med. , vol.15 , Issue.4 , pp. 410-416
    • Hammad, H.1    Chieppa, M.2    Perros, F.3    Willart, M.A.4    Germain, R.N.5    Lambrecht, B.N.6
  • 26
    • 79953046719 scopus 로고    scopus 로고
    • The inflammasome NLRs in immunity, inflammation, and associated diseases
    • Davis BK, Wen H, Ting JP. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu Rev Immunol. 2011;23(29):707-35.
    • (2011) Annu Rev Immunol. , vol.23 , Issue.29 , pp. 707-735
    • Davis, B.K.1    Wen, H.2    Ting, J.P.3
  • 27
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. 2008;320(5876): 674-7.
    • (2008) Science. , vol.320 , Issue.5876 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 29
    • 34047114821 scopus 로고    scopus 로고
    • Wound-induced ATP release and EGF receptor activation in epithelial cells
    • Yin J, Xu K, Zhang J, Kumar A, Yu FS. Wound-induced ATP release and EGF receptor activation in epithelial cells. J Cell Sci. 2007;120(Pt 5):815-25.
    • (2007) J Cell Sci. , vol.120 , Issue.PART 5 , pp. 815-825
    • Yin, J.1    Xu, K.2    Zhang, J.3    Kumar, A.4    Yu, F.S.5
  • 31
    • 79955040263 scopus 로고    scopus 로고
    • The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses
    • Kouzaki H, Iijima K, Kobayashi T, O'Grady SM, Kita H. The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J Immunol. 2011;186(7):4375-87.
    • (2011) J Immunol. , vol.18 , Issue.7 , pp. 4375-4387
    • Kouzaki, H.1    Iijima, K.2    Kobayashi, T.3    O'grady, S.M.4    Kita, H.5
  • 32
    • 40049088465 scopus 로고    scopus 로고
    • Dendritic cells and epithelial cells: Linking innate and adaptive immunity in asthma
    • Hammad H, Lambrecht BN. Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma. Nat Rev Immunol. 2008;8(3):193-204.
    • (2008) Nat Rev Immunol. , vol.8 , Issue.3 , pp. 193-204
    • Hammad, H.1    Lambrecht, B.N.2
  • 33
    • 63449124229 scopus 로고    scopus 로고
    • Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution
    • Ovrevik J, Lag M, Holme JA, Schwarze PE, Refsnes M. Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution. Toxicology. 2009;259(1-2):46-53.
    • (2009) Toxicology. , vol.259 , Issue.1-2 , pp. 46-53
    • Ovrevik, J.1    Lag, M.2    Holme, J.A.3    Schwarze, P.E.4    Refsnes, M.5
  • 34
    • 0038798012 scopus 로고    scopus 로고
    • Airway epithelial cells release MIP-3alpha/CCL20 in response to cytokines and ambient particulate matter
    • Reibman J, Hsu Y, Chen LC, Bleck B, Gordon T. Airway epithelial cells release MIP-3alpha/CCL20 in response to cytokines and ambient particulate matter. Am J Respir Cell Mol Biol. 2003;28(6):648-54.
    • (2003) Am J Respir Cell Mol Biol. , vol.28 , Issue.6 , pp. 648-654
    • Reibman, J.1    Hsu, Y.2    Chen, L.C.3    Bleck, B.4    Gordon, T.5
  • 35
    • 32044465280 scopus 로고    scopus 로고
    • A major lung CD103 (alphaE)-beta7 integrin-positive epithelial dendritic cell population expressing Langerin and tight junction proteins
    • Sung SS, Fu SM, Rose CE Jr, Gaskin F, Ju ST, Beaty SR. A major lung CD103 (alphaE)-beta7 integrin-positive epithelial dendritic cell population expressing Langerin and tight junction proteins. J Immunol. 2006;176(4):2161-72.
    • (2006) J Immunol. , vol.176 , Issue.4 , pp. 2161-2172
    • Sung, S.S.1    Fu, S.M.2    Rose Jr., C.E.3    Gaskin, F.4    Ju, S.T.5    Beaty, S.R.6
  • 36
    • 40149092686 scopus 로고    scopus 로고
    • Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin
    • Bleck B, Tse DB, Curotto de Lafaille MA, Zhang F, Reibman J. Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin. J Clin Immunol. 2008;28(2):147-56.
    • (2008) J Clin Immunol. , vol.28 , Issue.2 , pp. 147-156
    • Bleck, B.1    Tse, D.B.2    Curotto De Lafaille, M.A.3    Zhang, F.4    Reibman, J.5
  • 37
    • 55849148482 scopus 로고    scopus 로고
    • The cytokine network in asthma and chronic obstructive pulmonary disease
    • Barnes PJ. The cytokine network in asthma and chronic obstructive pulmonary disease. J Clin Invest. 2008;118(11): 3546-56.
    • (2008) J Clin Invest. , vol.118 , Issue.11 , pp. 3546-3556
    • Barnes, P.J.1
  • 38
    • 0037121946 scopus 로고    scopus 로고
    • Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen
    • Eisenbarth SC, Piggott DA, Huleatt JW, Visintin I, Herrick CA, Bottomly K. Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med. 2002;196(12):1645-51.
    • (2002) J Exp Med. , vol.196 , Issue.12 , pp. 1645-1651
    • Eisenbarth, S.C.1    Piggott, D.A.2    Huleatt, J.W.3    Visintin, I.4    Herrick, C.A.5    Bottomly, K.6
  • 39
    • 0037108373 scopus 로고    scopus 로고
    • House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: The cysteine protease allergen der p 1, activates proteaseactivated receptor (PAR)-2 and inactivates PAR-1
    • Asokananthan N, Graham PT, Stewart DJ, Bakker AJ, Eidne KA, Thompson PJ, Stewart GA. House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: the cysteine protease allergen, Der p 1, activates proteaseactivated receptor (PAR)-2 and inactivates PAR-1. J Immunol. 2002;169(8):4572-8.
    • (2002) J Immunol. , vol.169 , Issue.8 , pp. 4572-4578
    • Asokananthan, N.1    Graham, P.T.2    Stewart, D.J.3    Bakker, A.J.4    Eidne, K.A.5    Thompson, P.J.6    Stewart, G.A.7
  • 40
    • 0032193198 scopus 로고    scopus 로고
    • Dust mite proteolytic allergens induce cytokine release from cultured airway epithelium
    • King C, Brennan S, Thompson PJ, Stewart GA. Dust mite proteolytic allergens induce cytokine release from cultured airway epithelium. J Immunol. 1998;161(7):3645-51.
    • (1998) J Immunol. , vol.161 , Issue.7 , pp. 3645-3651
    • King, C.1    Brennan, S.2    Thompson, P.J.3    Stewart, G.A.4
  • 41
    • 0036788731 scopus 로고    scopus 로고
    • Size fractions of ambient particulate matter induce granulocyte macrophage colony-stimulating factor in human bronchial epithelial cells by mitogen-activated protein kinase pathways
    • Reibman J, Hsu Y, Chen LC, Kumar A, Su WC, Choy W, Talbot A, Gordon T. Size fractions of ambient particulate matter induce granulocyte macrophage colony-stimulating factor in human bronchial epithelial cells by mitogen-activated protein kinase pathways. Am J Respir Cell Mol Biol. 2002;27(4):455-62.
    • (2002) Am J Respir Cell Mol Biol. , vol.27 , Issue.4 , pp. 455-462
    • Reibman, J.1    Hsu, Y.2    Chen, L.C.3    Kumar, A.4    Su, W.C.5    Choy, W.6    Talbot, A.7    Gordon, T.8
  • 44
    • 0031572522 scopus 로고    scopus 로고
    • Molecular regulation of IL-6 activation by asbestos in lung epithelial cells: Role of reactive oxygen species
    • Simeonova PP, Toriumi W, Kommineni C, Erkan M, Munson AE, Rom WN, Luster MI. Molecular regulation of IL-6 activation by asbestos in lung epithelial cells: role of reactive oxygen species. J Immunol. 1997;159(8):3921-8.
    • (1997) J Immunol. , vol.159 , Issue.8 , pp. 3921-3928
    • Simeonova, P.P.1    Toriumi, W.2    Kommineni, C.3    Erkan, M.4    Munson, A.E.5    Rom, W.N.6    Luster, M.I.7
  • 49
    • 42649137213 scopus 로고    scopus 로고
    • T cell trafficking in allergic asthma: The ins and outs
    • Medoff BD, Thomas SY, Luster AD. T cell trafficking in allergic asthma: the ins and outs. Annu Rev Immunol. 2008;26: 205-32.
    • (2008) Annu Rev Immunol. , vol.26 , pp. 205-232
    • Medoff, B.D.1    Thomas, S.Y.2    Luster, A.D.3
  • 50
    • 0032768453 scopus 로고    scopus 로고
    • Stretch induces cytokine release by alveolar epithelial cells in vitro
    • Vlahakis NE, Schroeder MA, Limper AH, Hubmayr RD. Stretch induces cytokine release by alveolar epithelial cells in vitro. Am J Physiol. 1999;277(1 Pt 1):L167-73.
    • (1999) Am J Physiol. , vol.277 , Issue.1 PART 1
    • Vlahakis, N.E.1    Schroeder, M.A.2    Limper, A.H.3    Hubmayr, R.D.4
  • 51
    • 0034892244 scopus 로고    scopus 로고
    • Activation of the EGF receptor signaling pathway in airway epithelial cells exposed to Utah Valley PM
    • Wu W, Samet JM, Ghio AJ, Devlin RB. Activation of the EGF receptor signaling pathway in airway epithelial cells exposed to Utah Valley PM. Am J Physiol Lung Cell Mol Physiol. 2001;281(2):L483-9.
    • (2001) Am J Physiol Lung Cell Mol Physiol. , vol.281 , Issue.2
    • Wu, W.1    Samet, J.M.2    Ghio, A.J.3    Devlin, R.B.4
  • 52
    • 0029911395 scopus 로고    scopus 로고
    • Transcriptional activation of the interleukin-8 gene by respiratory syncytial virus infection in alveolar epithelial cells: Nuclear translocation of the RelA transcription factor as a mechanism producing airway mucosal inflammation
    • Garofalo R, Sabry M, Jamaluddin M, Yu RK, Casola A, Ogra PL, Brasier AR. Transcriptional activation of the interleukin-8 gene by respiratory syncytial virus infection in alveolar epithelial cells: nuclear translocation of the RelA transcription factor as a mechanism producing airway mucosal inflammation. J Virol. 1996;70(12):8773-81.
    • (1996) J Virol. , vol.70 , Issue.12 , pp. 8773-8781
    • Garofalo, R.1    Sabry, M.2    Jamaluddin, M.3    Yu, R.K.4    Casola, A.5    Ogra, P.L.6    Brasier, A.R.7
  • 53
    • 68149166400 scopus 로고    scopus 로고
    • IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells
    • Bautista MV, Chen Y, Ivanova VS, Rahimi MK, Watson AM, Rose MC. IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells. J Immunol. 2009;183(3):2159-66.
    • (2009) J Immunol. , vol.183 , Issue.3 , pp. 2159-2166
    • Bautista, M.V.1    Chen, Y.2    Ivanova, V.S.3    Rahimi, M.K.4    Watson, A.M.5    Rose, M.C.6
  • 54
    • 0035044065 scopus 로고    scopus 로고
    • Regulated production of the T helper 2-type T-cell chemoattractant TARC by human bronchial epithelial cells in vitro and in human lung xenografts
    • Berin MC, Eckmann L, Broide DH, Kagnoff MF. Regulated production of the T helper 2-type T-cell chemoattractant TARC by human bronchial epithelial cells in vitro and in human lung xenografts. Am J Respir Cell Mol Biol. 2001;24(4):382-9.
    • (2001) Am J Respir Cell Mol Biol. , vol.24 , Issue.4 , pp. 382-389
    • Berin, M.C.1    Eckmann, L.2    Broide, D.H.3    Kagnoff, M.F.4
  • 57
    • 25144525707 scopus 로고    scopus 로고
    • A role for TSLP in the development of inflammation in an asthma model
    • Al-Shami A, Spolski R, Kelly J, Keane-Myers A, Leonard WJ. A role for TSLP in the development of inflammation in an asthma model. J Exp Med. 2005;202(6):829-39.
    • (2005) J Exp Med. , vol.202 , Issue.6 , pp. 829-839
    • Al-Shami, A.1    Spolski, R.2    Kelly, J.3    Keane-Myers, A.4    Leonard, W.J.5
  • 59
    • 78650634881 scopus 로고    scopus 로고
    • Diesel exhaust particle-treated human bronchial epithelial cells upregulate Jagged-1 and OX40 ligand in myeloid dendritic cells via thymic stromal lymphopoietin
    • Bleck B, Tse DB, Gordon T, Ahsan MR, Reibman J. Diesel exhaust particle-treated human bronchial epithelial cells upregulate Jagged-1 and OX40 ligand in myeloid dendritic cells via thymic stromal lymphopoietin. J Immunol. 2010;185(11): 6636-45.
    • (2010) J Immunol. , vol.18 , Issue.11 , pp. 6636-6645
    • Bleck, B.1    Tse, D.B.2    Gordon, T.3    Ahsan, M.R.4    Reibman, J.5
  • 62
    • 78049277883 scopus 로고    scopus 로고
    • Innate immune cell populations function as initiators and effectors in Th2 cytokine responses
    • Saenz SA, Noti M, Artis D. Innate immune cell populations function as initiators and effectors in Th2 cytokine responses. Trends Immunol. 2010;31(11):407-13.
    • (2010) Trends Immunol. , vol.31 , Issue.11 , pp. 407-413
    • Saenz, S.A.1    Noti, M.2    Artis, D.3
  • 63
    • 79952531912 scopus 로고    scopus 로고
    • Type 2 innate immune responses and the natural helper cell
    • Koyasu S, Moro K. Type 2 innate immune responses and the natural helper cell. Immunology. 2011;132(4):475-81.
    • (2011) Immunology. , vol.13 , Issue.4 , pp. 475-481
    • Koyasu, S.1    Moro, K.2
  • 67
    • 80052267978 scopus 로고    scopus 로고
    • Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitro through a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism
    • e1-5
    • Li M, Li Q, Yang G, Kolosov VP, Perelman JM, Zhou XD. Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitro through a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism. J Allergy Clin Immunol. 2011;128(3):626-34 e1-5.
    • (2011) J Allergy Clin Immunol. , vol.128 , Issue.3 , pp. 626-634
    • Li, M.1    Li, Q.2    Yang, G.3    Kolosov, V.P.4    Perelman, J.M.5    Zhou, X.D.6
  • 68
    • 77956897439 scopus 로고    scopus 로고
    • The chitinase-like protein YKL-40 is secreted by airway epithelial cells at base line and in response to compressive mechanical stress
    • Park J-A, Drazen JM, Tschumperlin DJ. The chitinase-like protein YKL-40 is secreted by airway epithelial cells at base line and in response to compressive mechanical stress. J Biol Chem. 2010;285(39):29817-25.
    • (2010) J Biol Chem. , vol.28 , Issue.39 , pp. 29817-29825
    • Park, J.-A.1    Drazen, J.M.2    Tschumperlin, D.J.3
  • 72
    • 38049158195 scopus 로고    scopus 로고
    • Can inhaled corticosteroids influence the natural history of asthma?
    • Murray CS. Can inhaled corticosteroids influence the natural history of asthma? Curr Opin Allergy Clin Immunol. 2008;8(1): 77-81.
    • (2008) Curr Opin Allergy Clin Immunol. , vol.8 , Issue.1 , pp. 77-81
    • Murray, C.S.1
  • 73
    • 47949128719 scopus 로고    scopus 로고
    • Epidemiologic, experimental, and clinical links between respiratory syncytial virus infection and asthma
    • Mohapatra SS, Boyapalle S. Epidemiologic, experimental, and clinical links between respiratory syncytial virus infection and asthma. Clin Microbiol Rev. 2008;21(3):495-504.
    • (2008) Clin Microbiol Rev. , vol.21 , Issue.3 , pp. 495-504
    • Mohapatra, S.S.1    Boyapalle, S.2
  • 74
    • 2142808245 scopus 로고    scopus 로고
    • Respiratory syncytial virusinduced chemokine production: Linking viral replication to chemokine production in vitro and in vivo
    • Miller AL, Bowlin TL, Lukacs NW. Respiratory syncytial virusinduced chemokine production: linking viral replication to chemokine production in vitro and in vivo. J Infect Dis. 2004;189(8):1419-30.
    • (2004) J Infect Dis. , vol.189 , Issue.8 , pp. 1419-1430
    • Miller, A.L.1    Bowlin, T.L.2    Lukacs, N.W.3
  • 75
    • 0030794556 scopus 로고    scopus 로고
    • Respiratory syncytial virus infection results in airway hyperresponsiveness and enhanced airway sensitization to allergen
    • Schwarze J, Hamelmann E, Bradley KL, Takeda K, Gelfand EW. Respiratory syncytial virus infection results in airway hyperresponsiveness and enhanced airway sensitization to allergen. J Clin Invest. 1997;100(1):226-33.
    • (1997) J Clin Invest. , vol.100 , Issue.1 , pp. 226-233
    • Schwarze, J.1    Hamelmann, E.2    Bradley, K.L.3    Takeda, K.4    Gelfand, E.W.5
  • 76
    • 84866732227 scopus 로고    scopus 로고
    • The role of RSV infection in asthma initiation and progression: Findings in a mouse model
    • Han J, Takeda K, Gelfand EW. The role of RSV infection in asthma initiation and progression: findings in a mouse model. Pulm Med. 2011;2011:748038.
    • (2011) Pulm Med. , vol.2011 , pp. 748038
    • Han, J.1    Takeda, K.2    Gelfand, E.W.3
  • 78
    • 79951953564 scopus 로고    scopus 로고
    • TSLP from RSV-stimulated rat airway epithelial cells activates myeloid dendritic cells
    • Qiao J, Li A, Jin X. TSLP from RSV-stimulated rat airway epithelial cells activates myeloid dendritic cells. Immunol Cell Biol. 2011;89(2):231-8.
    • (2011) Immunol Cell Biol. , vol.89 , Issue.2 , pp. 231-238
    • Qiao, J.1    Li, A.2    Jin, X.3
  • 80
    • 1542347573 scopus 로고    scopus 로고
    • Viralinduced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells
    • Dahl ME, Dabbagh K, Liggitt D, Kim S, Lewis DB. Viralinduced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells. Nat Immunol. 2004;5(3):337-43.
    • (2004) Nat Immunol. , vol.5 , Issue.3 , pp. 337-343
    • Dahl, M.E.1    Dabbagh, K.2    Liggitt, D.3    Kim, S.4    Lewis, D.B.5
  • 81
    • 0036788817 scopus 로고    scopus 로고
    • Decreased distribution of lung epithelial junction proteins after intratracheal antigen or lipopolysaccharide challenge: Correlation with neutrophil influx and levels of BALF sE-cadherin
    • Evans SM, Blyth DI, Wong T, Sanjar S, West MR. Decreased distribution of lung epithelial junction proteins after intratracheal antigen or lipopolysaccharide challenge: correlation with neutrophil influx and levels of BALF sE-cadherin. Am J Respir Cell Mol Biol. 2002;27(4):446-54.
    • (2002) Am J Respir Cell Mol Biol. , vol.27 , Issue.4 , pp. 446-454
    • Evans, S.M.1    Blyth, D.I.2    Wong, T.3    Sanjar, S.4    West, M.R.5
  • 82
    • 34447581118 scopus 로고    scopus 로고
    • Keratinocyte growth factor improves alterations of lung permeability and bronchial epithelium in allergic rats
    • Tillie-Leblond I, Gosset P, Le Berre R, Janin A, Prangere T, Tonnel AB, Guery BP. Keratinocyte growth factor improves alterations of lung permeability and bronchial epithelium in allergic rats. Eur Respir J. 2007;30(1):31-9.
    • (2007) Eur Respir J. , vol.30 , Issue.1 , pp. 31-39
    • Tillie-Leblond, I.1    Gosset, P.2    Le Berre, R.3    Janin, A.4    Prangere, T.5    Tonnel, A.B.6    Guery, B.P.7
  • 83
    • 36849031788 scopus 로고    scopus 로고
    • Epithelium dysfunction in asthma
    • quiz 45-6
    • Holgate ST. Epithelium dysfunction in asthma. J Allergy Clin Immunol. 2007;120(6):1233-44; quiz 45-6.
    • (2007) J Allergy Clin Immunol. , vol.120 , Issue.6 , pp. 1233-1244
    • Holgate, S.T.1
  • 85
    • 30044442771 scopus 로고    scopus 로고
    • MAPK interacts with occludin and mediates EGF-induced prevention of tight junction disruption by hydrogen peroxide
    • Basuroy S, Seth A, Elias B, Naren AP, Rao R. MAPK interacts with occludin and mediates EGF-induced prevention of tight junction disruption by hydrogen peroxide. Biochem J. 2006; 393(Pt 1):69-77.
    • (2006) Biochem J. , vol.393 , Issue.PART 1 , pp. 69-77
    • Basuroy, S.1    Seth, A.2    Elias, B.3    Naren, A.P.4    Rao, R.5
  • 88
    • 70349664159 scopus 로고    scopus 로고
    • SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production
    • Chen G, Korfhagen TR, Xu Y, Kitzmiller J, Wert SE, Maeda Y, Gregorieff A, Clevers H, Whitsett JA. SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production. J Clin Invest. 2009;119(10):2914-24.
    • (2009) J Clin Invest. , vol.119 , Issue.10 , pp. 2914-2924
    • Chen, G.1    Korfhagen, T.R.2    Xu, Y.3    Kitzmiller, J.4    Wert, S.E.5    Maeda, Y.6    Gregorieff, A.7    Clevers, H.8    Whitsett, J.A.9
  • 93
    • 33846834049 scopus 로고    scopus 로고
    • Transcriptional control of lung morphogenesis
    • Maeda Y, Dave V, Whitsett JA. Transcriptional control of lung morphogenesis. Physiol Rev. 2007;87(1):219-44.
    • (2007) Physiol Rev. , vol.87 , Issue.1 , pp. 219-244
    • Maeda, Y.1    Dave, V.2    Whitsett, J.A.3
  • 94
    • 0028024585 scopus 로고
    • The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis
    • Bohinski RJ, Di Lauro R, Whitsett JA. The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis. Mol Cell Biol. 1994;14(9):5671-81.
    • (1994) Mol Cell Biol. , vol.14 , Issue.9 , pp. 5671-5681
    • Bohinski, R.J.1    Di Lauro, R.2    Whitsett, J.A.3
  • 97
    • 77956538031 scopus 로고    scopus 로고
    • Airway basal stem cells: A perspective on their roles in epithelial homeostasis and remodeling
    • Rock JR, Randell SH, Hogan BL. Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling. Dis Model Mech. 2010;3(9-10):545-56.
    • (2010) Dis Model Mech. , vol.3 , Issue.9-10 , pp. 545-556
    • Rock, J.R.1    Randell, S.H.2    Hogan, B.L.3
  • 98
  • 99
    • 79952221961 scopus 로고    scopus 로고
    • Tracking cell lineage to rediscover (again) the switch from ciliated to mucous cells
    • Patel AC, Brody SL, Stappenbeck TS, Holtzman MJ. Tracking cell lineage to rediscover (again) the switch from ciliated to mucous cells. Am J Respir Cell Mol Biol. 2011;44(3):261-3.
    • (2011) Am J Respir Cell Mol Biol. , vol.44 , Issue.3 , pp. 261-263
    • Patel, A.C.1    Brody, S.L.2    Stappenbeck, T.S.3    Holtzman, M.J.4
  • 101
    • 33748924799 scopus 로고    scopus 로고
    • Elimination of IL-13 reverses established goblet cell metaplasia into ciliated epithelia in airway epithelial cell culture
    • Kondo M, Tamaoki J, Takeyama K, Isono K, Kawatani K, Izumo T, Nagai A. Elimination of IL-13 reverses established goblet cell metaplasia into ciliated epithelia in airway epithelial cell culture. Allergol Int. 2006;55(3):329-36.
    • (2006) Allergol Int. , vol.55 , Issue.3 , pp. 329-336
    • Kondo, M.1    Tamaoki, J.2    Takeyama, K.3    Isono, K.4    Kawatani, K.5    Izumo, T.6    Nagai, A.7
  • 102
    • 16044371529 scopus 로고    scopus 로고
    • Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: Lymphocytic and eosinophilic inflammation without airway hyperreactivity
    • Rankin JA, Picarella DE, Geba GP, Temann UA, Prasad B, DiCosmo B, Tarallo A, Stripp B, Whitsett J, Flavell RA. Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc Natl Acad Sci USA 1996;93(15):7821-5.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.15 , pp. 7821-7825
    • Rankin, J.A.1    Picarella, D.E.2    Geba, G.P.3    Temann, U.A.4    Prasad, B.5    Dicosmo, B.6    Tarallo, A.7    Stripp, B.8    Whitsett, J.9    Flavell, R.A.10
  • 103
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest. 1999;103(6):779-88.
    • (1999) J Clin Invest. , vol.103 , Issue.6 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5    Wang, J.6    Zhang, Y.7    Elias, J.A.8
  • 105
    • 0035719955 scopus 로고    scopus 로고
    • Th2 cytokines and asthma. Interleukin-9 as a therapeutic target for asthma
    • Zhou Y, McLane M, Levitt RC. Th2 cytokines and asthma. Interleukin-9 as a therapeutic target for asthma. Respir Res. 2001;2(2):80-4.
    • (2001) Respir Res. , vol.2 , Issue.2 , pp. 80-84
    • Zhou, Y.1    McLane, M.2    Levitt, R.C.3
  • 106
    • 0033696860 scopus 로고    scopus 로고
    • IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development
    • Townsend JM, Fallon GP, Matthews JD, Smith P, Jolin EH, McKenzie NA. IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development. Immunity. 2000;13(4):573-83.
    • (2000) Immunity. , vol.13 , Issue.4 , pp. 573-583
    • Townsend, J.M.1    Fallon, G.P.2    Matthews, J.D.3    Smith, P.4    Jolin, E.H.5    McKenzie, N.A.6
  • 109
    • 0037593635 scopus 로고    scopus 로고
    • Interleukin-1 beta and tumor necrosis factor-alpha induce MUC5AC overexpression through a mechanism involving ERK/ p38 mitogen-activated protein kinases-MSK1-CREB activation in human airway epithelial cells
    • Song KS, Lee WJ, Chung KC, Koo JS, Yang EJ, Choi JY, Yoon JH. Interleukin-1 beta and tumor necrosis factor-alpha induce MUC5AC overexpression through a mechanism involving ERK/ p38 mitogen-activated protein kinases-MSK1-CREB activation in human airway epithelial cells. J Biol Chem. 2003;278(26): 23243-50.
    • (2003) J Biol Chem. , vol.278 , Issue.26 , pp. 23243-23250
    • Song, K.S.1    Lee, W.J.2    Chung, K.C.3    Koo, J.S.4    Yang, E.J.5    Choi, J.Y.6    Yoon, J.H.7
  • 110
    • 33846069779 scopus 로고    scopus 로고
    • IL-1beta disrupts postnatal lung morphogenesis in the mouse
    • Bry K, Whitsett JA, Lappalainen U. IL-1beta disrupts postnatal lung morphogenesis in the mouse. Am J Respir Cell Mol Biol. 2007;36(1):32-42.
    • (2007) Am J Respir Cell Mol Biol. , vol.36 , Issue.1 , pp. 32-42
    • Bry, K.1    Whitsett, J.A.2    Lappalainen, U.3
  • 111
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello CA. Biologic basis for interleukin-1 in disease. Blood. 1996;87(6):2095-147.
    • (1996) Blood. , vol.87 , Issue.6 , pp. 2095-2147
    • Dinarello, C.A.1
  • 114
    • 33745634410 scopus 로고    scopus 로고
    • Contribution of IL-18- induced innate T cell activation to airway inflammation with mucus hypersecretion and airway hyperresponsiveness
    • Ishikawa Y, Yoshimoto T, Nakanishi K. Contribution of IL-18- induced innate T cell activation to airway inflammation with mucus hypersecretion and airway hyperresponsiveness. Int Immunol. 2006;18(6):847-55.
    • (2006) Int Immunol. , vol.18 , Issue.6 , pp. 847-855
    • Ishikawa, Y.1    Yoshimoto, T.2    Nakanishi, K.3
  • 115
    • 84860321706 scopus 로고    scopus 로고
    • Interleukin-18 promoter polymorphism and asthma risk: A meta-analysis
    • Ma Y, Zhang B, Tang RK, Liu Y, Peng GG. Interleukin-18 promoter polymorphism and asthma risk: a meta-analysis. Mol Biol Rep. 2012;39(2):1371-6.
    • (2012) Mol Biol Rep. , vol.39 , Issue.2 , pp. 1371-1376
    • Ma, Y.1    Zhang, B.2    Tang, R.K.3    Liu, Y.4    Peng, G.G.5
  • 118
    • 0032536837 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production
    • Kuperman D, Schofield B, Wills-Karp M, Grusby MJ. Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. J Exp Med. 1998;187(6): 939-48.
    • (1998) J Exp Med. , vol.187 , Issue.6 , pp. 939-948
    • Kuperman, D.1    Schofield, B.2    Wills-Karp, M.3    Grusby, M.J.4
  • 119
    • 79751483223 scopus 로고    scopus 로고
    • Interleukin-13 induces mucin 5AC production involving STAT6/SPDEF in human airway epithelial cells
    • Yu H, Li Q, Kolosov VP, Perelman JM, Zhou X. Interleukin-13 induces mucin 5AC production involving STAT6/SPDEF in human airway epithelial cells. Cell Commun Adhes. 2010; 17(4-6):83-92.
    • (2010) Cell Commun Adhes. , vol.17 , Issue.4-6 , pp. 83-92
    • Yu, H.1    Li, Q.2    Kolosov, V.P.3    Perelman, J.M.4    Zhou, X.5
  • 123
    • 0033011603 scopus 로고    scopus 로고
    • The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma
    • Holgate ST, Lackie PM, Davies DE, Roche WR, Walls AF. The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma. Clin Exp Allergy. 1999;29(Suppl 2): 90-5.
    • (1999) Clin Exp Allergy. , vol.29 , Issue.SUPPL. 2 , pp. 90-95
    • Holgate, S.T.1    Lackie, P.M.2    Davies, D.E.3    Roche, W.R.4    Walls, A.F.5
  • 126
    • 0031731150 scopus 로고    scopus 로고
    • Activation and localization of transcription factor, nuclear factor- kappaB, in asthma
    • Hart LA, Krishnan VL, Adcock IM, Barnes PJ, Chung KF. Activation and localization of transcription factor, nuclear factor- kappaB, in asthma. Am J Respir Crit Care Med. 1998;158(5 Pt 1):1585-92.
    • (1998) Am J Respir Crit Care Med. , vol.158 , Issue.5 PART 1 , pp. 1585-1592
    • Hart, L.A.1    Krishnan, V.L.2    Adcock, I.M.3    Barnes, P.J.4    Chung, K.F.5
  • 127
    • 0029999428 scopus 로고    scopus 로고
    • Pathophysiology of asthma
    • Barnes PJ. Pathophysiology of asthma. Br J Clin Pharmacol. 1996;42(1):3-10.
    • (1996) Br J Clin Pharmacol. , vol.42 , Issue.1 , pp. 3-10
    • Barnes, P.J.1
  • 128
    • 0034665748 scopus 로고    scopus 로고
    • The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain
    • Nissen RM, Yamamoto KR. The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev. 2000;14(18):2314-29.
    • (2000) Genes Dev. , vol.14 , Issue.18 , pp. 2314-2329
    • Nissen, R.M.1    Yamamoto, K.R.2
  • 131
    • 29144479205 scopus 로고    scopus 로고
    • Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium
    • Broide DH, Lawrence T, Doherty T, Cho JY, Miller M, McElwain K, McElwain S, Karin M. Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium. Proc Natl Acad Sci USA 2005;102(49):17723-8.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.49 , pp. 17723-17728
    • Broide, D.H.1    Lawrence, T.2    Doherty, T.3    Cho, J.Y.4    Miller, M.5    McElwain, K.6    McElwain, S.7    Karin, M.8
  • 133
    • 78649986082 scopus 로고    scopus 로고
    • IkappaB kinase beta inhibitor IMD-0354 suppresses airway remodelling in a Dermatophagoides pteronyssinus-sensitized mouse model of chronic asthma
    • Ogawa H, Azuma M, Muto S, Nishioka Y, Honjo A, Tezuka T, Uehara H, Izumi K, Itai A, Sone S. IkappaB kinase beta inhibitor IMD-0354 suppresses airway remodelling in a Dermatophagoides pteronyssinus-sensitized mouse model of chronic asthma. Clin Exp Allergy. 2011;41(1):104-15.
    • (2011) Clin Exp Allergy. , vol.41 , Issue.1 , pp. 104-115
    • Ogawa, H.1    Azuma, M.2    Muto, S.3    Nishioka, Y.4    Honjo, A.5    Tezuka, T.6    Uehara, H.7    Izumi, K.8    Itai, A.9    Sone, S.10
  • 134
    • 57749114754 scopus 로고    scopus 로고
    • HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition
    • Thuault S, Tan EJ, Peinado H, Cano A, Heldin CH, Moustakas A. HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to- mesenchymal transition. J Biol Chem. 2008;283(48):33437-46.
    • (2008) J Biol Chem. , vol.283 , Issue.48 , pp. 33437-33446
    • Thuault, S.1    Tan, E.J.2    Peinado, H.3    Cano, A.4    Heldin, C.H.5    Moustakas, A.6
  • 135
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol. 2004;20:781-810.
    • (2004) Annu Rev Cell Dev Biol. , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 136
    • 84856692365 scopus 로고    scopus 로고
    • Beta- catenin determines upper airway progenitor cell fate and pre-invasive squamous lung cancer progression by modulating epithelial-to- mesenchymal transition
    • Giangreco A, Lu L, Vickers C, Teixeira VH, Groot KR, Ilieva EV, George J, Nicholson AG, Sage EK, Watt FM, Janes SM. beta- catenin determines upper airway progenitor cell fate and pre-invasive squamous lung cancer progression by modulating epithelial-to-mesenchymal transition. J Pathol. 2012;226(4): 575-87.
    • (2012) J Pathol. , vol.226 , Issue.4 , pp. 575-587
    • Giangreco, A.1    Lu, L.2    Vickers, C.3    Teixeira, V.H.4    Groot, K.R.5    Ilieva, E.V.6    George, J.7    Nicholson, A.G.8    Sage, E.K.9    Watt, F.M.10    Janes, S.M.11
  • 137
    • 15744374449 scopus 로고    scopus 로고
    • Wnt-dependent regulation of the E-cadherin repressor snail
    • Yook JI, Li XY, Ota I, Fearon ER, Weiss SJ. Wnt-dependent regulation of the E-cadherin repressor snail. J Biol Chem. 2005;280(12):11740-8.
    • (2005) J Biol Chem. , vol.280 , Issue.12 , pp. 11740-11748
    • Yook, J.I.1    Li, X.Y.2    Ota, I.3    Fearon, E.R.4    Weiss, S.J.5
  • 138
    • 79251638799 scopus 로고    scopus 로고
    • Chronic respiratory aeroallergen exposure in mice induces epithelial-mesenchymal transition in the large airways
    • Johnson JR, Roos A, Berg T, Nord M, Fuxe J. Chronic respiratory aeroallergen exposure in mice induces epithelial-mesenchymal transition in the large airways. PLoS ONE. 2011; 6(1):e16175.
    • (2011) PLoS ONE , vol.6 , Issue.1
    • Johnson, J.R.1    Roos, A.2    Berg, T.3    Nord, M.4    Fuxe, J.5
  • 140
    • 73949090678 scopus 로고    scopus 로고
    • TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids
    • Doerner AM, Zuraw BL. TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids. Respir Res. 2009;10:100.
    • (2009) Respir Res. , vol.10 , pp. 100
    • Doerner, A.M.1    Zuraw, B.L.2
  • 141
    • 80051788293 scopus 로고    scopus 로고
    • Matrix metalloprotease-9 induces transforming growth factor-beta(1) production in airway epithelium via activation of epidermal growth factor receptors
    • Perng DW, Chang KT, Su KC, Wu YC, Chen CS, Hsu WH, Tsai CM, Lee YC. Matrix metalloprotease-9 induces transforming growth factor-beta(1) production in airway epithelium via activation of epidermal growth factor receptors. Life Sci. 2011;89(5-6):204-12.
    • (2011) Life Sci , vol.89 , Issue.5-6 , pp. 204-212
    • Perng, D.W.1    Chang, K.T.2    Su, K.C.3    Wu, Y.C.4    Chen, C.S.5    Hsu, W.H.6    Tsai, C.M.7    Lee, Y.C.8
  • 143
    • 79960166023 scopus 로고    scopus 로고
    • Matrix metalloproteinases in acute lung injury: Mediators of injury and drivers of repair
    • Davey A, McAuley DF, O'Kane CM. Matrix metalloproteinases in acute lung injury: mediators of injury and drivers of repair. Eur Respir J. 2011;38(4):959-70.
    • (2011) Eur Respir J. , vol.38 , Issue.4 , pp. 959-970
    • Davey, A.1    McAuley, D.F.2    O'kane, C.M.3
  • 144
    • 0030895523 scopus 로고    scopus 로고
    • The measurement of reticular basement membrane and submucosal collagen in the asthmatic airway
    • Wilson JW, Li X. The measurement of reticular basement membrane and submucosal collagen in the asthmatic airway. Clin Exp Allergy. 1997;27(4):363-71.
    • (1997) Clin Exp Allergy. , vol.27 , Issue.4 , pp. 363-371
    • Wilson, J.W.1    Li, X.2
  • 145
    • 0344721504 scopus 로고    scopus 로고
    • Elastosis and fragmentation of fibers of the elastic system in fatal asthma
    • Mauad T, Xavier AC, Saldiva PH, Dolhnikoff M. Elastosis and fragmentation of fibers of the elastic system in fatal asthma. Am J Respir Crit Care Med. 1999;160(3):968-75.
    • (1999) Am J Respir Crit Care Med. , vol.160 , Issue.3 , pp. 968-975
    • Mauad, T.1    Xavier, A.C.2    Saldiva, P.H.3    Dolhnikoff, M.4
  • 148
    • 33748424832 scopus 로고    scopus 로고
    • The high-affinity IgE receptor (FcepsilonRI): A critical regulator of airway smooth muscle cells?
    • Gounni AS. The high-affinity IgE receptor (FcepsilonRI): a critical regulator of airway smooth muscle cells? Am J Physiol Lung Cell Mol Physiol. 2006;291(3):L312-21.
    • (2006) Am J Physiol Lung Cell Mol Physiol. , vol.291 , Issue.3
    • Gounni, A.S.1
  • 149
  • 150
    • 79959351840 scopus 로고    scopus 로고
    • Airway smooth muscle and immunomodulation in acute exacerbations of airway disease
    • Koziol-White CJ, Panettieri RA Jr. Airway smooth muscle and immunomodulation in acute exacerbations of airway disease. Immunol Rev. 2011;242(1):178-85.
    • (2011) Immunol Rev. , vol.242 , Issue.1 , pp. 178-185
    • Koziol-White, C.J.1    Panettieri Jr., R.A.2
  • 151
    • 67651162338 scopus 로고    scopus 로고
    • Noncontractile functions of airway smooth muscle cells in asthma
    • Tliba O, Panettieri RA Jr. Noncontractile functions of airway smooth muscle cells in asthma. Annu Rev Physiol. 2009;71: 509-35.
    • (2009) Annu Rev Physiol. , vol.71 , pp. 509-535
    • Tliba, O.1    Panettieri Jr., R.A.2
  • 155
    • 33646736505 scopus 로고    scopus 로고
    • Airway smooth muscle phenotype and function: Interactions with current asthma therapies
    • Halayko AJ, Tran T, Ji SY, Yamasaki A, Gosens R. Airway smooth muscle phenotype and function: interactions with current asthma therapies. Curr Drug Targets. 2006;7(5):525-40.
    • (2006) Curr Drug Targets. , vol.7 , Issue.5 , pp. 525-540
    • Halayko, A.J.1    Tran, T.2    Ji, S.Y.3    Yamasaki, A.4    Gosens, R.5
  • 157
    • 12744277963 scopus 로고    scopus 로고
    • Beta1-Integrins mediate enhancement of airway smooth muscle proliferation by collagen and fibronectin
    • Nguyen TT, Ward JP, Hirst SJ. beta1-Integrins mediate enhancement of airway smooth muscle proliferation by collagen and fibronectin. Am J Respir Crit Care Med. 2005;171(3): 217-23.
    • (2005) Am J Respir Crit Care Med. , vol.171 , Issue.3 , pp. 217-223
    • Nguyen, T.T.1    Ward, J.P.2    Hirst, S.J.3
  • 159
    • 0033823661 scopus 로고    scopus 로고
    • Differential effects of extracellular matrix proteins on human airway smooth muscle cell proliferation and phenotype
    • Hirst SJ, Twort CH, Lee TH. Differential effects of extracellular matrix proteins on human airway smooth muscle cell proliferation and phenotype. Am J Respir Cell Mol Biol. 2000;23(3): 335-44.
    • (2000) Am J Respir Cell Mol Biol. , vol.23 , Issue.3 , pp. 335-344
    • Hirst, S.J.1    Twort, C.H.2    Lee, T.H.3
  • 160
    • 0035185240 scopus 로고    scopus 로고
    • Effects of growth factors and extracellular matrix on survival of human airway smooth muscle cells
    • Freyer AM, Johnson SR, Hall IP. Effects of growth factors and extracellular matrix on survival of human airway smooth muscle cells. Am J Respir Cell Mol Biol. 2001;25(5):569-76.
    • (2001) Am J Respir Cell Mol Biol. , vol.25 , Issue.5 , pp. 569-576
    • Freyer, A.M.1    Johnson, S.R.2    Hall, I.P.3
  • 162
    • 74849084373 scopus 로고    scopus 로고
    • Airway structural components drive airway smooth muscle remodeling in asthma
    • Dekkers BG, Maarsingh H, Meurs H, Gosens R. Airway structural components drive airway smooth muscle remodeling in asthma. Proc Am Thorac Soc. 2009;6(8):683-92.
    • (2009) Proc Am Thorac Soc. , vol.6 , Issue.8 , pp. 683-692
    • Dekkers, B.G.1    Maarsingh, H.2    Meurs, H.3    Gosens, R.4
  • 163
    • 13544270246 scopus 로고    scopus 로고
    • Multiple beta 1 integrins mediate enhancement of human airway smooth muscle cytokine secretion by fibronectin and type i collagen
    • Peng Q, Lai D, Nguyen TT, Chan V, Matsuda T, Hirst SJ. Multiple beta 1 integrins mediate enhancement of human airway smooth muscle cytokine secretion by fibronectin and type I collagen. J Immunol. 2005;174(4):2258-64.
    • (2005) J Immunol. , vol.174 , Issue.4 , pp. 2258-2264
    • Peng, Q.1    Lai, D.2    Nguyen, T.T.3    Chan, V.4    Matsuda, T.5    Hirst, S.J.6
  • 170
    • 24644523574 scopus 로고    scopus 로고
    • Cyclic mechanical strain-induced proliferation and migration of human airway smooth muscle cells: Role of EMMPRIN and MMPs
    • Hasaneen NA, Zucker S, Cao J, Chiarelli C, Panettieri RA, Foda HD. Cyclic mechanical strain-induced proliferation and migration of human airway smooth muscle cells: role of EMMPRIN and MMPs. FASEB J. 2005;19(11):1507-9.
    • (2005) FASEB J. , vol.19 , Issue.11 , pp. 1507-1509
    • Hasaneen, N.A.1    Zucker, S.2    Cao, J.3    Chiarelli, C.4    Panettieri, R.A.5    Foda, H.D.6
  • 171
    • 77950925754 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 in asthmatic airway smooth muscle enlargement: Is fibroblast growth factor-2 required?
    • Bosse Y, Stankova J, Rola-Pleszczynski M. Transforming growth factor-beta1 in asthmatic airway smooth muscle enlargement: is fibroblast growth factor-2 required? Clin Exp Allergy 2010;40(5):710-24.
    • (2010) Clin Exp Allergy , vol.40 , Issue.5 , pp. 710-724
    • Bosse, Y.1    Stankova, J.2    Rola-Pleszczynski, M.3
  • 172
    • 71849090786 scopus 로고    scopus 로고
    • Tissue remodeling induced by hypersecreted epidermal growth factor and amphiregulin in the airway after an acute asthma attack
    • e1-7
    • Enomoto Y, Orihara K, Takamasu T, Matsuda A, Gon Y, Saito H, Ra C, Okayama Y. Tissue remodeling induced by hypersecreted epidermal growth factor and amphiregulin in the airway after an acute asthma attack. J Allergy Clin Immunol. 2009;124(5):913-20 e1-7.
    • (2009) J Allergy Clin Immunol. , vol.124 , Issue.5 , pp. 913-920
    • Enomoto, Y.1    Orihara, K.2    Takamasu, T.3    Matsuda, A.4    Gon, Y.5    Saito, H.6    Ra, C.7    Okayama, Y.8
  • 173
    • 84860469330 scopus 로고    scopus 로고
    • Brain derived neurotrophic factor induces proliferation of human airway smooth muscle cells
    • doi:10.1111/ j.1582-4934.2011.01356.x
    • Aravamudan B, Thompson M, Pabelick C, Prakash YS. Brain derived neurotrophic factor induces proliferation of human airway smooth muscle cells. J Cell Mol Med. 2011. doi:10.1111/ j.1582-4934.2011.01356.x.
    • (2011) J Cell Mol Med.
    • Aravamudan, B.1    Thompson, M.2    Pabelick, C.3    Prakash, Y.S.4
  • 174
    • 0032407674 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: Role in mediating airway smooth muscle proliferation
    • Walker TR, Moore SM, Lawson MF, Panettieri RA Jr, Chilvers ER. Platelet-derived growth factor-BB and thrombin activate phosphoinositide 3-kinase and protein kinase B: role in mediating airway smooth muscle proliferation. Mol Pharmacol. 1998;54(6):1007-15.
    • (1998) Mol Pharmacol. , vol.54 , Issue.6 , pp. 1007-1015
    • Walker, T.R.1    Moore, S.M.2    Lawson, M.F.3    Panettieri Jr., R.A.4    Chilvers, E.R.5
  • 178
    • 77951665424 scopus 로고    scopus 로고
    • Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes
    • e13
    • Hastie AT, Moore WC, Meyers DA, Vestal PL, Li H, Peters SP, Bleecker ER. Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes. J Allergy Clin Immunol. 2010;125(5):1028-36 e13.
    • (2010) J Allergy Clin Immunol. , vol.125 , Issue.5 , pp. 1028-1036
    • Hastie, A.T.1    Moore, W.C.2    Meyers, D.A.3    Vestal, P.L.4    Li, H.5    Peters, S.P.6    Bleecker, E.R.7
  • 179
    • 34248189075 scopus 로고    scopus 로고
    • Mast cell regulation of airway smooth muscle function in asthma
    • Bradding P. Mast cell regulation of airway smooth muscle function in asthma. Eur Respir J. 2007;29(5):827-30.
    • (2007) Eur Respir J. , vol.29 , Issue.5 , pp. 827-830
    • Bradding, P.1
  • 182
    • 53149123285 scopus 로고    scopus 로고
    • Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: Cooperative roles for CADM1, stem cell factor, and IL-6
    • Hollins F, Kaur D, Yang W, Cruse G, Saunders R, Sutcliffe A, Berger P, Ito A, Brightling CE, Bradding P. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J Immunol. 2008;181(4):2772-80.
    • (2008) J Immunol. , vol.181 , Issue.4 , pp. 2772-2780
    • Hollins, F.1    Kaur, D.2    Yang, W.3    Cruse, G.4    Saunders, R.5    Sutcliffe, A.6    Berger, P.7    Ito, A.8    Brightling, C.E.9    Bradding, P.10
  • 183
    • 77954115305 scopus 로고    scopus 로고
    • Mast cells in allergy and infection: Versatile effector and regulatory cells in innate and adaptive immunity
    • Galli SJ, Tsai M. Mast cells in allergy and infection: versatile effector and regulatory cells in innate and adaptive immunity. Eur J Immunol. 2010;40(7):1843-51.
    • (2010) Eur J Immunol. , vol.40 , Issue.7 , pp. 1843-1851
    • Galli, S.J.1    Tsai, M.2
  • 184
  • 185
    • 0025763220 scopus 로고
    • Release of both preformed and newly synthesized tumor necrosis factor alpha (TNF-alpha)/cachectin by mouse mast cells stimulated via the Fc epsilon RI. A mechanism for the sustained action of mast cell-derived TNF-alpha during IgE-dependent biological responses
    • Gordon JR, Galli SJ. Release of both preformed and newly synthesized tumor necrosis factor alpha (TNF-alpha)/cachectin by mouse mast cells stimulated via the Fc epsilon RI. A mechanism for the sustained action of mast cell-derived TNF-alpha during IgE-dependent biological responses. J Exp Med. 1991;174(1): 103-7.
    • (1991) J Exp Med. , vol.174 , Issue.1 , pp. 103-107
    • Gordon, J.R.1    Galli, S.J.2
  • 187
    • 65349112520 scopus 로고    scopus 로고
    • The significance of OX40 and OX40L to T-cell biology and immune disease
    • Croft M, So T, Duan W, Soroosh P. The significance of OX40 and OX40L to T-cell biology and immune disease. Immunol Rev. 2009;229(1):173-91.
    • (2009) Immunol Rev. , vol.229 , Issue.1 , pp. 173-191
    • Croft, M.1    So, T.2    Duan, W.3    Soroosh, P.4
  • 188
    • 34548646019 scopus 로고    scopus 로고
    • Cutting edge: OX40 inhibits TGF-beta- and antigen-driven conversion of naive CD4 T cells into CD25? Foxp3? T cells
    • So T, Croft M. Cutting edge: OX40 inhibits TGF-beta- and antigen-driven conversion of naive CD4 T cells into CD25? Foxp3? T cells. J Immunol. 2007;179(3):1427-30.
    • (2007) J Immunol. , vol.179 , Issue.3 , pp. 1427-1430
    • So, T.1    Croft, M.2
  • 190
    • 74249116206 scopus 로고    scopus 로고
    • Respiratory viral infections in infants: Causes, clinical symptoms, virology, and immunology
    • Tregoning JS, Schwarze J. Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology. Clin Microbiol Rev. 2010;23(1):74-98.
    • (2010) Clin Microbiol Rev. , vol.23 , Issue.1 , pp. 74-98
    • Tregoning, J.S.1    Schwarze, J.2
  • 192
    • 77956354206 scopus 로고    scopus 로고
    • Role of viral respiratory infections in asthma and asthma exacerbations
    • Busse WW, Lemanske RF Jr, Gern JE. Role of viral respiratory infections in asthma and asthma exacerbations. Lancet. 2010;376(9743):826-34.
    • (2010) Lancet. , vol.376 , Issue.9743 , pp. 826-834
    • Busse, W.W.1    Lemanske Jr., R.F.2    Gern, J.E.3
  • 194
    • 12544255563 scopus 로고    scopus 로고
    • Activation of the epidermal growth factor receptor by respiratory syncytial virus results in increased inflammation and delayed apoptosis
    • Monick MM, Cameron K, Staber J, Powers LS, Yarovinsky TO, Koland JG, Hunninghake GW. Activation of the epidermal growth factor receptor by respiratory syncytial virus results in increased inflammation and delayed apoptosis. J Biol Chem. 2005;280(3):2147-58.
    • (2005) J Biol Chem. , vol.280 , Issue.3 , pp. 2147-2158
    • Monick, M.M.1    Cameron, K.2    Staber, J.3    Powers, L.S.4    Yarovinsky, T.O.5    Koland, J.G.6    Hunninghake, G.W.7


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