-
1
-
-
0037364976
-
Regulatory T cells in transplantation tolerance
-
Wood KJ, Sagaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol. 2003;3:199-210.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 199-210
-
-
Wood, K.J.1
Sagaguchi, S.2
-
2
-
-
16844378209
-
Natural regulatory T cells and self-tolerance
-
Schwartz RH. Natural regulatory T cells and self-tolerance. Nat Immunol. 2005;6:327-330.
-
(2005)
Nat Immunol
, vol.6
, pp. 327-330
-
-
Schwartz, R.H.1
-
3
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
Kim JM, Rasmussen JP, Rudensky AY. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat Immunol. 2007;8:1-7.
-
(2007)
Nat Immunol
, vol.8
, pp. 1-7
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
4
-
-
2442484053
-
Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi S. Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol. 2004;22:531-562.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
5
-
-
0033929005
-
Identification of a previously unknown antigen-specific regulatory Tcells and its mechanism of suppression
-
Zhang ZX, Yang L, Young KJ, DuTemple B, Zhang L. Identification of a previously unknown antigen-specific regulatory Tcells and its mechanism of suppression. Nat Med. 2000;6:782-789.
-
(2000)
Nat Med
, vol.6
, pp. 782-789
-
-
Zhang, Z.X.1
Yang, L.2
Young, K.J.3
DuTemple, B.4
Zhang, L.5
-
6
-
-
29244435493
-
Inducing and expanding regulatory T cell populations by foreign antigen
-
Kretschmer K, Apostolou I, Hawiger D, Khazaie K, Nussenzweig MC, Von Boehmer H. Inducing and expanding regulatory T cell populations by foreign antigen. Nat Immunol. 2005;6:1219-1227.
-
(2005)
Nat Immunol
, vol.6
, pp. 1219-1227
-
-
Kretschmer, K.1
Apostolou, I.2
Hawiger, D.3
Khazaie, K.4
Nussenzweig, M.C.5
Von Boehmer, H.6
-
7
-
-
28244471125
-
-
Rudensky A. Foxp3 and dominant tolerance. Philos Trans R Soc Lond B Biol Sci. 2005;360:1645-1646.
-
Rudensky A. Foxp3 and dominant tolerance. Philos Trans R Soc Lond B Biol Sci. 2005;360:1645-1646.
-
-
-
-
8
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003;299:1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
9
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot JD, Gavin MA, Rudensky A. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol. 2003;4:330-336.
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.3
-
10
-
-
15544384475
-
Essential role for interleukin-2 for CD4+CD25+ T regulatory cell development during the neonatal period
-
Bayer AL, Yu A, Adeegbe D, Malek TR. Essential role for interleukin-2 for CD4+CD25+ T regulatory cell development during the neonatal period. J Exp Med. 2005;201:769-777.
-
(2005)
J Exp Med
, vol.201
, pp. 769-777
-
-
Bayer, A.L.1
Yu, A.2
Adeegbe, D.3
Malek, T.R.4
-
11
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-{beta} induction of transcription factor Foxp3
-
Chen W, Jin W, Hardegen N, et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-{beta} induction of transcription factor Foxp3. J Exp Med. 2003;198:1875-1886.
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
-
13
-
-
2942592429
-
Therapeutic targeting of the effector T cell costimulatory molecule OX40
-
Sugamura K, Ishii N, Weinberg AD. Therapeutic targeting of the effector T cell costimulatory molecule OX40. Nature Rev Immunol. 2004;4:420-431.
-
(2004)
Nature Rev Immunol
, vol.4
, pp. 420-431
-
-
Sugamura, K.1
Ishii, N.2
Weinberg, A.D.3
-
14
-
-
0141609073
-
Co-stimulatory members of the TNFR family: Keys to effective T cell immunity?
-
Croft M. Co-stimulatory members of the TNFR family: keys to effective T cell immunity? Nat Rev Immunol. 2003;3:609-620.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 609-620
-
-
Croft, M.1
-
15
-
-
0345447614
-
OX40-mediated memory T cell generation is TNF receptor-associated factor 2 dependent
-
Prell RA, Evans DE, Thalhofer C, Shi T, Funatake C, Weinberg AD. OX40-mediated memory T cell generation is TNF receptor-associated factor 2 dependent. J Immunol. 2003;171:5997-6005.
-
(2003)
J Immunol
, vol.171
, pp. 5997-6005
-
-
Prell, R.A.1
Evans, D.E.2
Thalhofer, C.3
Shi, T.4
Funatake, C.5
Weinberg, A.D.6
-
16
-
-
0034881390
-
Signaling through OX40 (CD134) breaks peripheral T cell tolerance
-
Bansal-Pakala P, Jember AG, Croft M. Signaling through OX40 (CD134) breaks peripheral T cell tolerance. Nat Med. 2001;7:907-912.
-
(2001)
Nat Med
, vol.7
, pp. 907-912
-
-
Bansal-Pakala, P.1
Jember, A.G.2
Croft, M.3
-
17
-
-
1642485023
-
Critical role of OX40 in CD28 and CD154 independent rejection
-
Demirci G, Amanullah F, Kewalaramani R, et al. Critical role of OX40 in CD28 and CD154 independent rejection. J Immunol. 2004;172:1691-1698.
-
(2004)
J Immunol
, vol.172
, pp. 1691-1698
-
-
Demirci, G.1
Amanullah, F.2
Kewalaramani, R.3
-
18
-
-
1542514775
-
Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells
-
Takeda I, Ine S, Killeen N, et al. Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells. J Immunol. 2004;172:3580-3589.
-
(2004)
J Immunol
, vol.172
, pp. 3580-3589
-
-
Takeda, I.1
Ine, S.2
Killeen, N.3
-
19
-
-
14744285671
-
Triggering of OX40 (CD134) on CD4+CD25+ T cells blocks their inhibitory activity: A novel regulatory role for OX40 and its comparison with GITR
-
Valzasina B, Guiducci C, Dislich H, Killeen N, Weinberg AD, Colombo MP. Triggering of OX40 (CD134) on CD4+CD25+ T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR. Blood. 2005;105:2845-2851.
-
(2005)
Blood
, vol.105
, pp. 2845-2851
-
-
Valzasina, B.1
Guiducci, C.2
Dislich, H.3
Killeen, N.4
Weinberg, A.D.5
Colombo, M.P.6
-
20
-
-
0344286707
-
Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40)
-
Pippig SD, Pena-Rossi C, Long J, et al. Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40). J Immunol. 1999;163:6520-6529.
-
(1999)
J Immunol
, vol.163
, pp. 6520-6529
-
-
Pippig, S.D.1
Pena-Rossi, C.2
Long, J.3
-
21
-
-
0033427044
-
OX40 ligand has a critical costimulatory role in dendritic cell:T cell interactions
-
Chen AI, McAdam AJ, Buhlmann JE, et al. OX40 ligand has a critical costimulatory role in dendritic cell:T cell interactions. Immunity. 1999;11:689-698.
-
(1999)
Immunity
, vol.11
, pp. 689-698
-
-
Chen, A.I.1
McAdam, A.J.2
Buhlmann, J.E.3
-
22
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory cells
-
Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory cells. Nature. 2006;441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
-
23
-
-
0035132135
-
IL-15 and IL-2: A matter of life and death for T cells in vivo
-
Li XC, Demirci G, Lacraz SF, et al. IL-15 and IL-2: a matter of life and death for T cells in vivo. Nat Med. 2001;7:114-118.
-
(2001)
Nat Med
, vol.7
, pp. 114-118
-
-
Li, X.C.1
Demirci, G.2
Lacraz, S.F.3
-
24
-
-
31144460031
-
Critical, but conditional, role of OX40 in memory T cell-mediated rejection
-
Vu MD, Clarkson MR, Yagita H, Turka LA, Sayegh MH, Li XC. Critical, but conditional, role of OX40 in memory T cell-mediated rejection. J Immunol. 2006;176:1394-1401.
-
(2006)
J Immunol
, vol.176
, pp. 1394-1401
-
-
Vu, M.D.1
Clarkson, M.R.2
Yagita, H.3
Turka, L.A.4
Sayegh, M.H.5
Li, X.C.6
-
25
-
-
0004880266
-
CTLA-4 signals are required to optimally induce allograft tolerance with combined donor specific transfusion and anti-CD154 monoclonal antibody treatment
-
Zheng XX, Markees TG, Hancock WW, et al. CTLA-4 signals are required to optimally induce allograft tolerance with combined donor specific transfusion and anti-CD154 monoclonal antibody treatment. J Immunol. 1999;162:4983-4990.
-
(1999)
J Immunol
, vol.162
, pp. 4983-4990
-
-
Zheng, X.X.1
Markees, T.G.2
Hancock, W.W.3
-
26
-
-
0027383870
-
Cloning of mouse Ox40: A T cell activation marker that may mediate T-B cell interactions
-
Calderhead DM, Buhlmann JE, van den Eertwegh AJ, Claassen E, Noelle RJ, Fell HP. Cloning of mouse Ox40: a T cell activation marker that may mediate T-B cell interactions. J Immunol. 1993;151:5261-5271.
-
(1993)
J Immunol
, vol.151
, pp. 5261-5271
-
-
Calderhead, D.M.1
Buhlmann, J.E.2
van den Eertwegh, A.J.3
Claassen, E.4
Noelle, R.J.5
Fell, H.P.6
-
27
-
-
0037443415
-
The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo
-
Yuan X, Salama AD, Dong V, et al. The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo. J Immunol. 2003;170:2949-2955.
-
(2003)
J Immunol
, vol.170
, pp. 2949-2955
-
-
Yuan, X.1
Salama, A.D.2
Dong, V.3
-
28
-
-
0034177891
-
Blockade of CD134 (OX40)-CD134L interaction ameliorates lethal acute graft-versus-host disease in a murine model of allogeneic bone marrow transplantation
-
Tsukada N, Akiba H, Kobata T, Aizawa Y, Yagita H, Okumura K. Blockade of CD134 (OX40)-CD134L interaction ameliorates lethal acute graft-versus-host disease in a murine model of allogeneic bone marrow transplantation. Blood. 2000;95:2434-2439.
-
(2000)
Blood
, vol.95
, pp. 2434-2439
-
-
Tsukada, N.1
Akiba, H.2
Kobata, T.3
Aizawa, Y.4
Yagita, H.5
Okumura, K.6
-
29
-
-
0035451519
-
Critical involvement of OX40 ligand signals in the T cell priming events during experimental autoimmune encephalomyelitis
-
Ndhlovu LC, Ishii N, Murata K, Sato T, Sugamura K. Critical involvement of OX40 ligand signals in the T cell priming events during experimental autoimmune encephalomyelitis. J Immunol. 2001;167:2991-2999.
-
(2001)
J Immunol
, vol.167
, pp. 2991-2999
-
-
Ndhlovu, L.C.1
Ishii, N.2
Murata, K.3
Sato, T.4
Sugamura, K.5
-
30
-
-
0035808782
-
Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40
-
Jember AG-H, Zuberi R, Liu F-T, Croft M. Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40. J Exp Med. 2001;193:387-392.
-
(2001)
J Exp Med
, vol.193
, pp. 387-392
-
-
Jember, A.G.-H.1
Zuberi, R.2
Liu, F.-T.3
Croft, M.4
-
31
-
-
0035092850
-
CD28-independent induction of experimental autoimmune encephalomyelitis
-
Chitnis T, Najafian N, Abdallah KA, et al. CD28-independent induction of experimental autoimmune encephalomyelitis. J Clin Invest. 2001;107:575-583.
-
(2001)
J Clin Invest
, vol.107
, pp. 575-583
-
-
Chitnis, T.1
Najafian, N.2
Abdallah, K.A.3
-
32
-
-
0037528710
-
Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients
-
Blazar BR, Sharpe AH, Chen AI, et al. Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients. Blood. 2003;101:3741-3748.
-
(2003)
Blood
, vol.101
, pp. 3741-3748
-
-
Blazar, B.R.1
Sharpe, A.H.2
Chen, A.I.3
-
33
-
-
30744445700
-
OX40 costimulation synergizes with GM-CSF whole-cell vaccination to overcome established CD8+ T cell tolerance to an endogenous tumor antigen
-
Murata S, Ladle BH, Kim PS, et al. OX40 costimulation synergizes with GM-CSF whole-cell vaccination to overcome established CD8+ T cell tolerance to an endogenous tumor antigen. J Immunol. 2006;176:974-983.
-
(2006)
J Immunol
, vol.176
, pp. 974-983
-
-
Murata, S.1
Ladle, B.H.2
Kim, P.S.3
-
34
-
-
0033682056
-
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
-
Salomon B, Lenschow DJ, Rhee L, et al. B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity. 2000;12:431-440.
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
Lenschow, D.J.2
Rhee, L.3
-
35
-
-
0036170938
-
Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance
-
Shimizu J, Yamazaki S, Takahashi T, Ishida Y, Sakaguchi S. Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol. 2002;3:135-142.
-
(2002)
Nat Immunol
, vol.3
, pp. 135-142
-
-
Shimizu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
36
-
-
0034710983
-
Pinpointing when T cell costimulaotry receptor CTLA-4 must be engaged to dampen diabetogenic T cells
-
Luhder F, Chambers C, Allison JP, Benoist C, Mathis D. Pinpointing when T cell costimulaotry receptor CTLA-4 must be engaged to dampen diabetogenic T cells. Proc Natl Acad Sci U S A. 2000;97:12204-12209.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12204-12209
-
-
Luhder, F.1
Chambers, C.2
Allison, J.P.3
Benoist, C.4
Mathis, D.5
-
37
-
-
32444432610
-
-
Sutmuller RPM, den Brok MHMGM, Kramer M, et al. Toll-like receptor 2 controls expansion and function of regulatory T cells. J Clin Invest. 2006;116:485-494.
-
Sutmuller RPM, den Brok MHMGM, Kramer M, et al. Toll-like receptor 2 controls expansion and function of regulatory T cells. J Clin Invest. 2006;116:485-494.
-
-
-
-
38
-
-
0141920662
-
Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells
-
Tang Q, Henriksen KJ, Boden EK, et al. Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells. J Immunol. 2003;171:3348-3352.
-
(2003)
J Immunol
, vol.171
, pp. 3348-3352
-
-
Tang, Q.1
Henriksen, K.J.2
Boden, E.K.3
-
39
-
-
12344307563
-
Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus
-
Liang S, Alard P, Zhao Y, Parnell S, Clark SL, Kosiewicz MM. Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus. J Exp Med. 2005;201:127-137.
-
(2005)
J Exp Med
, vol.201
, pp. 127-137
-
-
Liang, S.1
Alard, P.2
Zhao, Y.3
Parnell, S.4
Clark, S.L.5
Kosiewicz, M.M.6
-
40
-
-
6344279933
-
Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells
-
Stephens GL, McHugh RS, Whitters MJ, et al. Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells. J Immunol. 2004;173:5008-5020.
-
(2004)
J Immunol
, vol.173
, pp. 5008-5020
-
-
Stephens, G.L.1
McHugh, R.S.2
Whitters, M.J.3
-
41
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in ctla-4
-
Waterhouse P, Penninger JM, Timms E, et al. Lymphoproliferative disorders with early lethality in mice deficient in ctla-4. Science. 1995;270:985-988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
-
42
-
-
0031091743
-
-
Bluestone JA. Is CTLA-4 a master switch for peripheral T cell tolerance? J Immunol. 1997;158:1989-1993.
-
Bluestone JA. Is CTLA-4 a master switch for peripheral T cell tolerance? J Immunol. 1997;158:1989-1993.
-
-
-
-
43
-
-
0042662863
-
OX40 (CD134) controls memory T Helper 2 cells that drive lung inflammation
-
Salek-Ardakani S, Song J, Halteman BS, et al. OX40 (CD134) controls memory T Helper 2 cells that drive lung inflammation. J Exp Med. 2003;198:315-324.
-
(2003)
J Exp Med
, vol.198
, pp. 315-324
-
-
Salek-Ardakani, S.1
Song, J.2
Halteman, B.S.3
-
44
-
-
0034677054
-
Role of OX40 signals in coordinating CD4 T cell selection, migration, and cytokine differentiation in Th1 and Th2 cells
-
Lane P. Role of OX40 signals in coordinating CD4 T cell selection, migration, and cytokine differentiation in Th1 and Th2 cells. J Exp Med. 2000;191:201-205.
-
(2000)
J Exp Med
, vol.191
, pp. 201-205
-
-
Lane, P.1
-
45
-
-
8444234229
-
4-1BB and OX40 act independently to facilitate robust CD8 and CD4 recall responses
-
Dawicki W, Bertram EM, Sharpe AH, Watts TH. 4-1BB and OX40 act independently to facilitate robust CD8 and CD4 recall responses. J Immunol. 2004;173:5944-5951.
-
(2004)
J Immunol
, vol.173
, pp. 5944-5951
-
-
Dawicki, W.1
Bertram, E.M.2
Sharpe, A.H.3
Watts, T.H.4
-
46
-
-
33748362628
-
OX40 ligand shuts down IL-10-producing regulatory T cells
-
Ito T, Wang Y-H, Duramad O, et al. OX40 ligand shuts down IL-10-producing regulatory T cells. Proc Natl Acad Sci U S A. 2006;103:13138-13143.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 13138-13143
-
-
Ito, T.1
Wang, Y.-H.2
Duramad, O.3
-
47
-
-
3042800728
-
Donor-specific transplantation tolerance: The paradoxical behavior of CD4+CD25+ T cells
-
Graca L, Le Moine A, Lin C-Y, Fairchild PJ, Cobbold SP, Waldmann H. Donor-specific transplantation tolerance: the paradoxical behavior of CD4+CD25+ T cells. Proc Natl Acad Sci U S A. 2004;101:10122-10126.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10122-10126
-
-
Graca, L.1
Le Moine, A.2
Lin, C.-Y.3
Fairchild, P.J.4
Cobbold, S.P.5
Waldmann, H.6
-
48
-
-
33645286546
-
T cells, tumor immunity and immunotherapy
-
Zou W. Regulatory T cells, tumor immunity and immunotherapy. Nat Rev Immunol. 2006;6:295-306.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 295-306
-
-
Regulatory, Z.W.1
|