Molecular Regulation of IL-6 Activation by Asbestos in Lung Epithelial Cells: Role of Reactive Oxygen Species

Journal of Immunology

Volumn 159, Issue 8, 1997, Pages 3921-3928

  Simeonova, Petia P ^a   Toriumi, Wataru ^a,c   Kommineni, Choudari ^a   Erkan, Muge ^b   Munson, Albert E ^a   Rom, William N ^b   Luster, Michael I ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CROCIDOLITE; INTERLEUKIN 6; NUCLEAR PROTEIN; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL CULTURE; CHEMISTRY; DRUG EFFECT; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; LUNG; LUNG ALVEOLUS CELL CARCINOMA; LUNG LAVAGE; LUNG TUMOR; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; SECRETION;

ADENOCARCINOMA, BRONCHIOLO-ALVEOLAR; ASBESTOS, CROCIDOLITE; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-6; LUNG; LUNG NEOPLASMS; NUCLEAR PROTEINS; OXIDATION-REDUCTION; PROTEIN BINDING; REACTIVE OXYGEN SPECIES; TUMOR CELLS, CULTURED;

EID: 0031572522     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Mossman, B. T., and J. B. L. Gee. 1989. Medical progress: asbestos related diseases. N. Engl. J. Med. 320:1721.
2. Driscoll, K. E., D. G. Hassenbein, J. Carter, J. Poynter, T. N. Asquth, R. A. Grant, J. Whitten, M. P. Purdon, and R. Takigiku. 1993. Macrophage inflammatory proteins 1 and 2: expression by rat alveolar macrophages, fibroblasts, and epithelial cells and in rat lung after mineral dust exposure. Am. J. Respir. Cell Mol. Biol. 8:311.
3. Bonner, J. C., A. L. Goodell, P. G. Coin, and A. R. Brody. 1993. Chrysotile asbestos upregulates gene expression and production of α-receptors for platelet-derived growth factor (PDGF-AA) on rat lung fibroblasts. J. Clin. Invest. 92:425.
4. Li, X. Y., D. Lamb, and K. Donaldson. 1993. The production of TNF-α and IL-1-like activity by bronchoalveolar leucocytes after intratracheal instillation of crocidolite asbestos. Int. J. Exp. Pathol. 74:403.
5. Perkins, R. C., R. K. Scheule, R. Hamilton, G. Gomes, G. Freidman, and A. Holian. 1993. Human alveolar macrophage cytokine release in response to in vitro and in vivo asbestos exposure. Exp. Lung Res. 19:55.
6. Rom, W. N., W. D. Travis, and A. R. Brody. 1991. Cellular and molecular basis of the asbestos-related diseases. Am. Rev. Respir. Dis. 143:408.
7. Simeonova, P. P., and M. I. Luster. 1995. Iron and reactive oxygen species in the asbestos-induced tumor necrosis factor-α (TNF-α) response from alveolar macrophages. Am. J. Respir. Cell Mol. Biol. 12:676.
8. Janssen, Y. M. W., A. Barchowsky, M. Treadwell, K. E. Driscoll, and B. Mossman. 1995. Asbestos induces nuclear factor κB (NF-κB) DNA-binding activity and NF-κB-dependent gene expression in tracheal epithelial cells. Proc. Natl. Acad. Sci. USA 92:8458.
9. Simeonova, P. P., and M. I. Luster. 1996. Asbestos induction of nuclear transcription factors and IL-8 gene regulation. Am. J. Respir. Cell Mol. Biol. 15:787.
10. Pahl, H. L., and P. A. Baeuerle. 1994. Oxygen and the control of gene expression. Bioessays 16:497.
11. Meyer, M., H. L. Pahl, and P. A. Baeuerle. 1994. Regulation of the transcription factors NF-κB and AP-1 by redox changes. Chem. Biol. Interact. 91:91.
12. Hirano, T. 1992. Interleukin-6 and its relation to inflammation and disease. Clin. Immunol. Immunopathol. 62:S60.
13. Jones, K. P., S. P. Reynolds, S. J. Capper, S. Kalinka, J. H. Edwards, and B. H. Davies. 1991. Measurement of interleukin-6 in bronchoalveolar lavage fluid by radioimmunoassay: differences between patients with interstitial lung disease and control subjects. Clin. Exp. Immunol. 83:30.
14. Devlin, R. B., W. F. McDonnell, R. Mann, S. Becker, D. E. House, D. Schreinemachers, and H. Koren. 1991. Exposure of humans to ambient levels of ozone for 6.6 hours causes cellular and biochemical changes in the lung. Am. J. Respir. Cell Mol. Biol. 4:72.
15. Vanhee, D., P. Gosset, A. Boitelle, B. Wallaert, and A. B. Tonnel. 1995. Cytokines and cytokine network in silicosis and coal workers' pneumoconiosis. Eur. Respir. J. 8:834.
16. Cromwell, O., Q. Hamid, C. J. Corrigan, J. Barkans, Q. Meng, and P. D. Collins. 1992. Expression and generation of interleukin-8,1L-6 and granulocyte-macrophage colony-stimulating factor by bronchial epithelial cells and enhancement by IL-1β and tumor necrosis factor α. Immunology 77:330.
17. Crestani, B., P. Cornillet, M. Dehoux, C. Rolland, M. Guenounou, and M. Aubier. 1994. Alveolar type II epithelial cells produce interleukin-6 in vitro and in vivo. J. Clin. Invest. 94:731.
18. Arnold, R., B. Humbert, H. Werchau, H. Gallati, and W. Konig. 1994. Interleukin-8, interleukin-6, and soluble tumour necrosis factor receptor type I release from a human pulmonary epithelial cell line (A549) exposed to respiratory syncytial virus. Immunology 82:126.
19. Devlin, R. B., K. P. McKinnon, T. Noah, S. Becker, and H. S. Koren. 1994. Ozone-induced release of cytokines and fibronectin by alveolar macrophages and airway epithelial cells. Am. J. Physiol. 266:L612.
20. Elias, J. A., V. Lentz, and P. Cummings. 1991. Transforming growth factor-β regulation of IL-6 production by unstimulated and IL-1 stimulated human fibroblasts. J. Immunol. 146:3437.
21. Kotloff, R. M., J. Little, and J. A. Elias. 1990. Human alveolar macrophage and blood monocyte interleukin-6 production. Am. J. Respir. Cell Mol. Biol. 3497.
22. Zhang, Y., M. Broser, and W. N. Rom. 1994. Activation of the interleukin 6 gene by Mycobacterium tuberculosis or lipopolysaccharide is mediated by nuclear factors NF-IL6 and NF-κB. Proc. Natl. Acad. Sci. USA 91:2225.
23. Dendorfer, U., P. Oettgen, and T. A. Libermann. 1994. Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide. Mol. Cell. Biol. 14:4443.
24. Matsusaka, T., K. Fujikawa, Y. Nishio, N. Mukaida, K. Matsushima, T. Kishimoto, and S. Akira. 1993. Transcription factors NF-IL-6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. Proc. Natl. Acad. Sci. USA 90:10193.
25. Kopp, E. B., and S. Ghosh. 1995. NF-κB and Rel proteins in innate immunity. Adv. Immunol. 58:1.
26. Lieber, M., B. Smith, A. Szakal, W. Nelson-Rees, and G. Todaro. 1976. A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. Int. J. Cancer 17:62.
27. Rosenthal, G. J., R. P. Stranahan, M. M. Fort, and M. I. Luster. 1989. The role of alveolar macrophage activation in the response to mineral fibers. In Effects of Mineral Dusts on Cells, NATO ASI Series Vol. H30. B. T. Mossman and R. O. Begin, eds. Springer-Verlag, Berlin, p. 329.
28. Wang, A. M., M. V. Doyle, and D. F. Mark. 1989. Quantitation of mRNA by the polymerase chain reaction. Proc. Nat. Acad. Sci. USA 86:9717.
29. Schreiber, E., P. Matthias, M. M. Muller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with "mini-extracts," prepared from a small number of cells. Nucleic Acids Res. 17:6420.
30. Pennypacker, K. R., L. Thai, J.-S. Hong, and M. K. McMillian. 1994. Prolonged expression of AP-1 transcription factors in the rat hippocampus after systematic kainate treatment. J. Neurosci. 14:3998.
31. Koren, H. S., R. B. Devlin, D. E. Grahamm R. Mann, M. P. McGee, D. H. Horstman, W. J. Kozumbo, S. Becker, D. E. House, W. F. McDonnell, and P. A. Bromberg. 1989. Ozone-induced inflammation in the lower airways of human subjects. Am. Rev. Respir. Dis. 139:407.
32. Akira, S., H. Isshiki, T. Sugita, O. Tanabe, S. Kinoshita, Y. Nishio, T. Nakajima, T. Hirano, and T. Kishimoto. 1990. A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J. 9:1897.
33. Crouch, E. 1990. Pathobiology of pulmonary fibrosis. Am. J. Physiol. 259: L159.
34. Adler, K. B., B. M. Fischer, D. T. Wright, L. A. Cohn, and S. Becker. 1994. Interactions between respiratory epithelial cells and cytokines: relationship to lung inflammation. Ann. NY Acad. Sci. 725:128.
35. Rosenthal, G. J., D. R. Germolec, M. E. Blazka, E. Corsini, P. Simeonova, P. Pollock, L.-Y. Kong, J. Kwon, and M. I. Luster. 1994. Asbestos stimulated IL-8 production from human lung epithelial cells. J. Immunol. 153:3237.
36. 3+]. Arch. Biochem. Biophys. 298:646.
37. Trautwein, C., C. Caelles, P. van der Geer, T. Hunter, M. Karin, and M. Chojkier. 1993. Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain. Nature 364:544.
38. Yan, S. F., I. Tritto, D. Pinsky, H. Liao, J. Huang, G. Fuller, J. Brett, L. May, and D. Stern. Induction of interleukin 6 (IL-6) by hypoxia in vascular cells. J. Biol. Chem. 270:11463.
39. DiCosmo, B. F., G. P. Geba, D. Picarella, J. A. Elias, J. A. Rankin, B. R. Stripp, J. A. Whitsett, and R. A. Flavell. 1994. Airway epithelial cell expression of interleukin-6 in transgenic mice: uncoupling of airway inflammation and bronchial hyperactivity. J. Clin. Invest. 94:2028.
40. Fries, K. M., M. E. Felch, and R. P. Phipps. 1994. Interleukin-6 is an autocrine growth factor for murine lung fibroblast subsets. Am. J. Respir. Cell. Biol. 11: 552.
41. Bonfield, T. L., J. R. Panuska, M. W. Konstan, K. A. Hilliard, H. Ghnaim, and M. Berger. 1995. Inflammatory cytokines in cystic fibrosis lungs. Am. J. Respir. Crit. Care Med. 152:2111.