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Volumn 117, Issue 4, 2007, Pages 978-988

SPDEF regulates goblet cell hyperplasia in the airway epithelium

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXY TERMINAL DOMAIN OF THYROID TRANSCRIPTION FACTOR 1; HOUSE DUST ALLERGEN; INTERLEUKIN 13; SENESCENCE ACCELERATED MOUSE POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS; TRANSCRIPTION FACTOR FOXJ1; TRANSCRIPTION FACTOR SCGB1A1; TRANSCRIPTION FACTOR SFTPA; TRANSCRIPTION FACTOR SOX17; UNCLASSIFIED DRUG;

EID: 34147151188     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI29176     Document Type: Article
Times cited : (227)

References (46)
  • 1
    • 0035153026 scopus 로고    scopus 로고
    • Airway goblet-cell mucus secretion
    • Jackson, A.D. 2001. Airway goblet-cell mucus secretion. Trends Pharmacol. Sci. 22:39-45.
    • (2001) Trends Pharmacol. Sci , vol.22 , pp. 39-45
    • Jackson, A.D.1
  • 2
    • 0035378557 scopus 로고    scopus 로고
    • The role of epidermal growth factor in mucus production
    • Nadel, J.A., and Burgel, P.R. 2001. The role of epidermal growth factor in mucus production. Curr. Opin. Pharmacol. 1:254-258.
    • (2001) Curr. Opin. Pharmacol , vol.1 , pp. 254-258
    • Nadel, J.A.1    Burgel, P.R.2
  • 3
    • 2342523999 scopus 로고    scopus 로고
    • Airway mucus hypersecretion in asthma: An undervalued pathology?
    • Rogers, D.F. 2004. Airway mucus hypersecretion in asthma: an undervalued pathology? Curr. Opin. Pharmacol. 4:241-250.
    • (2004) Curr. Opin. Pharmacol , vol.4 , pp. 241-250
    • Rogers, D.F.1
  • 4
    • 0344629659 scopus 로고    scopus 로고
    • Nuclear factor I/thyroid transcription factor 1 interactions modulate surfactant protein C transcription
    • Bachurski, C.J., Yang, G.H., Currier, T.A., Gronostajski, R.M., and Hong, D. 2003. Nuclear factor I/thyroid transcription factor 1 interactions modulate surfactant protein C transcription. Mol. Cell. Biol. 23:9014-9024.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 9014-9024
    • Bachurski, C.J.1    Yang, G.H.2    Currier, T.A.3    Gronostajski, R.M.4    Hong, D.5
  • 5
    • 0032530312 scopus 로고    scopus 로고
    • Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry
    • Chen, J., Knowles, H.J., Hebert, J.L., and Hackett, B.P. 1998. Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry. J. Clin. Invest. 102:1077-1082.
    • (1998) J. Clin. Invest , vol.102 , pp. 1077-1082
    • Chen, J.1    Knowles, H.J.2    Hebert, J.L.3    Hackett, B.P.4
  • 6
    • 0030057596 scopus 로고    scopus 로고
    • The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
    • Kimura, S., et al. 1996. The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev. 10:60-69.
    • (1996) Genes Dev , vol.10 , pp. 60-69
    • Kimura, S.1
  • 8
    • 27944500309 scopus 로고    scopus 로고
    • β-Catenin regulates differentiation of respiratory epithelial cells in vivo
    • Mucenski, M.L., et al. 2005. β-Catenin regulates differentiation of respiratory epithelial cells in vivo. Am. J. Physiol. Lung Cell. Mol. Physiol. 289:L971-L979.
    • (2005) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.289
    • Mucenski, M.L.1
  • 9
    • 1342283994 scopus 로고    scopus 로고
    • Foxa2 regulates alveolarization and goblet cell hyperplasia
    • Wan, H., et al. 2004. Foxa2 regulates alveolarization and goblet cell hyperplasia. Development. 131:953-964.
    • (2004) Development , vol.131 , pp. 953-964
    • Wan, H.1
  • 10
    • 5144226404 scopus 로고    scopus 로고
    • Foxa2 is required for transition to air breathing at birth
    • Wan, H., et al. 2004. Foxa2 is required for transition to air breathing at birth. Proc. Natl. Acad. Sci. U. S. A. 101:14449-14454.
    • (2004) Proc. Natl. Acad. Sci. U. S. A , vol.101 , pp. 14449-14454
    • Wan, H.1
  • 11
    • 17144407948 scopus 로고    scopus 로고
    • Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis
    • Wan, H., et al. 2005. Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis. J. Biol. Chem. 280:13809-13816.
    • (2005) J. Biol. Chem , vol.280 , pp. 13809-13816
    • Wan, H.1
  • 12
    • 0036337973 scopus 로고    scopus 로고
    • GATA6 regulates differentiation of distal lung epithelium
    • Yang, H., Lu, M.M., Zhang, L., Whitsett, J.A., and Morrisey, E.E. 2002. GATA6 regulates differentiation of distal lung epithelium. Development. 129:2233-2246.
    • (2002) Development , vol.129 , pp. 2233-2246
    • Yang, H.1    Lu, M.M.2    Zhang, L.3    Whitsett, J.A.4    Morrisey, E.E.5
  • 13
    • 0028024585 scopus 로고
    • The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis
    • Bohinski, R.J., DiLauro, R., and Whitsett, J.A. 1994. The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis. Mol. Cell. Biol. 14:5671-5681.
    • (1994) Mol. Cell. Biol , vol.14 , pp. 5671-5681
    • Bohinski, R.J.1    DiLauro, R.2    Whitsett, J.A.3
  • 14
    • 85177000620 scopus 로고    scopus 로고
    • Bruno, M.D., Bohinski, R.J., Huelsman, K.M., Whitsett, J.A., and Korfhagen, T.R. 1995. Lung cell-specific expression of the murine surfactant protein A (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1 [erratum 1995, 270:16482]. J. Biol. Chem. 270:6531-6536.
    • Bruno, M.D., Bohinski, R.J., Huelsman, K.M., Whitsett, J.A., and Korfhagen, T.R. 1995. Lung cell-specific expression of the murine surfactant protein A (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1 [erratum 1995, 270:16482]. J. Biol. Chem. 270:6531-6536.
  • 15
    • 0029962808 scopus 로고    scopus 로고
    • Transcription of the lungspecific surfactant protein C gene is mediated by thyroid transcription factor 1
    • Kelly, S.E., Bachurski, C.J., Burhans, M.S., and Glasser, S.W. 1996. Transcription of the lungspecific surfactant protein C gene is mediated by thyroid transcription factor 1. J. Biol. Chem. 271:6881-6888.
    • (1996) J. Biol. Chem , vol.271 , pp. 6881-6888
    • Kelly, S.E.1    Bachurski, C.J.2    Burhans, M.S.3    Glasser, S.W.4
  • 16
    • 0029913604 scopus 로고    scopus 로고
    • Transcriptional regulation of a mouse Clara cell-specific protein (mCC10) gene by the NKx transcription factor family members thyroid transcription factor 1 and cardiac muscle-specific homeobox protein (CSX)
    • Ray, M.K., Chen, C.Y., Schwartz, R.J., and DeMayo, F.J. 1996. Transcriptional regulation of a mouse Clara cell-specific protein (mCC10) gene by the NKx transcription factor family members thyroid transcription factor 1 and cardiac muscle-specific homeobox protein (CSX). Mol. Cell. Biol. 16:2056-2064.
    • (1996) Mol. Cell. Biol , vol.16 , pp. 2056-2064
    • Ray, M.K.1    Chen, C.Y.2    Schwartz, R.J.3    DeMayo, F.J.4
  • 17
    • 0037040178 scopus 로고    scopus 로고
    • GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression
    • Liu, C., Glasser, S.W., Wan, H., and Whitsett, J.A. 2002. GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression. J. Biol. Chem. 277:4519-4525.
    • (2002) J. Biol. Chem , vol.277 , pp. 4519-4525
    • Liu, C.1    Glasser, S.W.2    Wan, H.3    Whitsett, J.A.4
  • 18
    • 0034614639 scopus 로고    scopus 로고
    • Retinoic acid stimulation of the human surfactant protein B promoter is thyroid transcription factor 1 site-dependent
    • Naltner, A., Ghaffari, M., Whitsett, J.A., and Yan, C. 2000. Retinoic acid stimulation of the human surfactant protein B promoter is thyroid transcription factor 1 site-dependent. J. Biol. Chem. 275:56-62.
    • (2000) J. Biol. Chem , vol.275 , pp. 56-62
    • Naltner, A.1    Ghaffari, M.2    Whitsett, J.A.3    Yan, C.4
  • 19
    • 2342442849 scopus 로고    scopus 로고
    • TAZ interacts with TTF-1 and regulates expression of surfactant protein-C
    • Park, K.S., et al. 2004. TAZ interacts with TTF-1 and regulates expression of surfactant protein-C. J. Biol. Chem. 279:17384- 17390.
    • (2004) J. Biol. Chem , vol.279 , pp. 17384-17390
    • Park, K.S.1
  • 20
    • 0035877819 scopus 로고    scopus 로고
    • Protein-protein interaction of retinoic acid receptor alpha and thyroid transcription factor-1 in respiratory epithelial cells
    • Yan, C., Naltner, A., Conkright, J., and Ghaffari, M. 2001. Protein-protein interaction of retinoic acid receptor alpha and thyroid transcription factor-1 in respiratory epithelial cells. J. Biol. Chem. 276:21686-21691.
    • (2001) J. Biol. Chem , vol.276 , pp. 21686-21691
    • Yan, C.1    Naltner, A.2    Conkright, J.3    Ghaffari, M.4
  • 21
    • 0037169507 scopus 로고    scopus 로고
    • Role of CBP/p300 and SRC-1 in transcriptional regulation of the pulmonary surfactant protein-A (SP-A) gene by thyroid transcription factor-1 (TTF-1)
    • Yi, M., Tong, G.X., Murry, B., and Mendelson, C.R. 2002. Role of CBP/p300 and SRC-1 in transcriptional regulation of the pulmonary surfactant protein-A (SP-A) gene by thyroid transcription factor-1 (TTF-1). J. Biol. Chem. 277:2997-3005.
    • (2002) J. Biol. Chem , vol.277 , pp. 2997-3005
    • Yi, M.1    Tong, G.X.2    Murry, B.3    Mendelson, C.R.4
  • 23
    • 0042817958 scopus 로고    scopus 로고
    • TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue-specific gene expression
    • deFelice, M., et al. 2003. TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue-specific gene expression. J. Biol. Chem. 278:35574-35583.
    • (2003) J. Biol. Chem , vol.278 , pp. 35574-35583
    • deFelice, M.1
  • 24
    • 0033957171 scopus 로고    scopus 로고
    • PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression
    • Oettgen, P., et al. 2000. PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression. J. Biol. Chem. 275:1216-1225.
    • (2000) J. Biol. Chem , vol.275 , pp. 1216-1225
    • Oettgen, P.1
  • 25
    • 0033987251 scopus 로고    scopus 로고
    • Cloning and expression of the mouse Pse gene encoding a novel Ets family member
    • Yamada, N., Tamai, Y., Miyamoto, H., and Nozaki, M. 2000. Cloning and expression of the mouse Pse gene encoding a novel Ets family member. Gene. 241:267-274.
    • (2000) Gene , vol.241 , pp. 267-274
    • Yamada, N.1    Tamai, Y.2    Miyamoto, H.3    Nozaki, M.4
  • 26
    • 0027304054 scopus 로고
    • Developmental expression of SP-A and SP-A mRNA in the proximal and distal respiratory epithelium in the human fetus and newborn
    • Khoor, A., Gray, M.E., Hull, W.M., Whitsett, J.A., and Stahlman, M.T. 1993. Developmental expression of SP-A and SP-A mRNA in the proximal and distal respiratory epithelium in the human fetus and newborn. J. Histochem. Cytochem. 41:1311-1319.
    • (1993) J. Histochem. Cytochem , vol.41 , pp. 1311-1319
    • Khoor, A.1    Gray, M.E.2    Hull, W.M.3    Whitsett, J.A.4    Stahlman, M.T.5
  • 27
    • 0025120749 scopus 로고
    • The ETS-domain: A new DNA-binding motif that recognizes a purine-rich core DNA sequence
    • Karim, F.D., et al. 1990. The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence. Genes Dev. 4:1451-1453.
    • (1990) Genes Dev , vol.4 , pp. 1451-1453
    • Karim, F.D.1
  • 28
    • 0042162959 scopus 로고    scopus 로고
    • Role for ETS domain transcription factors Pea3/Erm in mouse lung development
    • Liu, Y., Jiang, H., Crawford, H.C., and Hogan, B.L. 2003. Role for ETS domain transcription factors Pea3/Erm in mouse lung development. Dev. Biol. 261:10-24.
    • (2003) Dev. Biol , vol.261 , pp. 10-24
    • Liu, Y.1    Jiang, H.2    Crawford, H.C.3    Hogan, B.L.4
  • 29
    • 33745183342 scopus 로고    scopus 로고
    • Erm/ thyroid transcription factor 1 interactions modulate surfactant protein C transcription
    • Lin, S., Perl, A.K., and Shannon, J.M. 2006. Erm/ thyroid transcription factor 1 interactions modulate surfactant protein C transcription. J. Biol. Chem. 281:16716-16726.
    • (2006) J. Biol. Chem , vol.281 , pp. 16716-16726
    • Lin, S.1    Perl, A.K.2    Shannon, J.M.3
  • 30
    • 0036008331 scopus 로고    scopus 로고
    • Conditional gene expression in the respiratory epithelium of the mouse
    • Perl, A.K., Tichelaar, J.W., and Whitsett, J.A. 2002. Conditional gene expression in the respiratory epithelium of the mouse. Transgenic Res. 11:21-29.
    • (2002) Transgenic Res , vol.11 , pp. 21-29
    • Perl, A.K.1    Tichelaar, J.W.2    Whitsett, J.A.3
  • 31
    • 27644491560 scopus 로고    scopus 로고
    • Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli
    • Perl, A.K., et al. 2005. Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli. Am. J. Respir. Cell Mol. Biol. 33:455-462.
    • (2005) Am. J. Respir. Cell Mol. Biol , vol.33 , pp. 455-462
    • Perl, A.K.1
  • 32
    • 0031280279 scopus 로고    scopus 로고
    • Interleukin-4 alters epithelial cell differentiation and surfactant homeostasis in the postnatal mouse lung
    • Jain-Vora, S., Wert, S.E., Temann, U.A., Rankin, J.A., and Whitsett, J.A. 1997. Interleukin-4 alters epithelial cell differentiation and surfactant homeostasis in the postnatal mouse lung. Am. J. Respir. Cell Mol. Biol. 17:541-551.
    • (1997) Am. J. Respir. Cell Mol. Biol , vol.17 , pp. 541-551
    • Jain-Vora, S.1    Wert, S.E.2    Temann, U.A.3    Rankin, J.A.4    Whitsett, J.A.5
  • 33
    • 0036344597 scopus 로고    scopus 로고
    • Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma
    • Kuperman, D.A., et al. 2002. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat. Med. 8:885-889.
    • (2002) Nat. Med , vol.8 , pp. 885-889
    • Kuperman, D.A.1
  • 34
    • 16044371529 scopus 로고    scopus 로고
    • Phenotypic and physiolog ic characterization of transgenic mice expressing interleukin 4 in the lung: Lymphocytic and eosinophilic inflammation without airway hyperreactivity
    • Rankin, J.A., et al. 1996. Phenotypic and physiolog ic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc. Natl. Acad. Sci. U. S. A. 93:7821-7825.
    • (1996) Proc. Natl. Acad. Sci. U. S. A , vol.93 , pp. 7821-7825
    • Rankin, J.A.1
  • 35
    • 0032545213 scopus 로고    scopus 로고
    • Interleukin-13: Central mediator of allergic asthma
    • Wills-Karp, M., et al. 1998. Interleukin-13: central mediator of allergic asthma. Science. 282:2258-2261.
    • (1998) Science , vol.282 , pp. 2258-2261
    • Wills-Karp, M.1
  • 36
    • 0035084068 scopus 로고    scopus 로고
    • Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice
    • Tomkinson, A., et al. 2001. Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice. Am. J. Respir. Crit. Care Med. 163:721-730.
    • (2001) Am. J. Respir. Crit. Care Med , vol.163 , pp. 721-730
    • Tomkinson, A.1
  • 37
    • 0037081280 scopus 로고    scopus 로고
    • NKX-3.1 interacts with prostate-derived Ets factor and regulates the activity of the PSA promoter
    • Chen, H., Nandi, A.K., Li, X., and Bieberich, C.J. 2002. NKX-3.1 interacts with prostate-derived Ets factor and regulates the activity of the PSA promoter. Cancer Res. 62:338-340.
    • (2002) Cancer Res , vol.62 , pp. 338-340
    • Chen, H.1    Nandi, A.K.2    Li, X.3    Bieberich, C.J.4
  • 38
    • 26944474424 scopus 로고    scopus 로고
    • Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation
    • Shroyer, N.F., Wallis, D., Venken, K.J., Bellen, H.J., and Zoghbi, H.Y. 2005. Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 19:2412-2417.
    • (2005) Genes Dev , vol.19 , pp. 2412-2417
    • Shroyer, N.F.1    Wallis, D.2    Venken, K.J.3    Bellen, H.J.4    Zoghbi, H.Y.5
  • 39
    • 0025010740 scopus 로고
    • Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity
    • Guazzi, S., et al. 1990. Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity. EMBO J. 9:3631-3639.
    • (1990) EMBO J , vol.9 , pp. 3631-3639
    • Guazzi, S.1
  • 41
    • 0032549673 scopus 로고    scopus 로고
    • Cloning of the aminoterminal and 5′-flanking region of the human MUC5AC mucin gene and transcriptional upregulation by bacterial exoproducts
    • Li, D., Gallup, M., Fan, N., Szymkowski, D.E., and Basbaum, C.B. 1998. Cloning of the aminoterminal and 5′-flanking region of the human MUC5AC mucin gene and transcriptional upregulation by bacterial exoproducts. J. Biol. Chem. 273:6812-6820.
    • (1998) J. Biol. Chem , vol.273 , pp. 6812-6820
    • Li, D.1    Gallup, M.2    Fan, N.3    Szymkowski, D.E.4    Basbaum, C.B.5
  • 42
    • 33646253175 scopus 로고    scopus 로고
    • Sox17 influences the differentiation of respiratory epithelial cells
    • Park, K.-S., Wells, J.M., Zorn, A.M., Wert, S.E., and Whitsett, J.A. 2006. Sox17 influences the differentiation of respiratory epithelial cells. Dev. Biol. 294:192-202.
    • (2006) Dev. Biol , vol.294 , pp. 192-202
    • Park, K.-S.1    Wells, J.M.2    Zorn, A.M.3    Wert, S.E.4    Whitsett, J.A.5
  • 43
    • 0037083525 scopus 로고    scopus 로고
    • Increased expression of thyroid transcription factor-1 (TTF-1) in respiratory epithelial cells inhibits alveolarization and causes pulmonary inflammation
    • Wert, S.E., Dey, C.R., Blair, P.A., Kimura, S., and Whitsett, J.A. 2002. Increased expression of thyroid transcription factor-1 (TTF-1) in respiratory epithelial cells inhibits alveolarization and causes pulmonary inflammation. Dev. Biol. 242:75-87.
    • (2002) Dev. Biol , vol.242 , pp. 75-87
    • Wert, S.E.1    Dey, C.R.2    Blair, P.A.3    Kimura, S.4    Whitsett, J.A.5
  • 44
    • 0029815021 scopus 로고    scopus 로고
    • Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung
    • Zhou, L., Lim, L., Costa, R.H., and Whitsett, J.A. 1996. Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung. J. Histochem. Cytochem. 44:1183-1193.
    • (1996) J. Histochem. Cytochem , vol.44 , pp. 1183-1193
    • Zhou, L.1    Lim, L.2    Costa, R.H.3    Whitsett, J.A.4
  • 45
    • 0027471741 scopus 로고
    • Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice
    • Wert, S.E., Glasser, S.W., Korfhagen, T.R., and Whitsett, J.A. 1993. Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice. Dev. Biol. 156:426-443.
    • (1993) Dev. Biol , vol.156 , pp. 426-443
    • Wert, S.E.1    Glasser, S.W.2    Korfhagen, T.R.3    Whitsett, J.A.4
  • 46
    • 0032167664 scopus 로고    scopus 로고
    • Impaired development of Th2 cells in IL-13-deficient mice
    • McKenzie, G.J., et al. 1999. Impaired development of Th2 cells in IL-13-deficient mice. Immunity. 9:423-432.
    • (1999) Immunity , vol.9 , pp. 423-432
    • McKenzie, G.J.1


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