Mast-cell infiltration of airway smooth muscle in asthma

New England Journal of Medicine

Volumn 346, Issue 22, 2002, Pages 1699-1705

  Brightling, Christopher E ^a   Bradding, Peter ^a   Symon, Fiona A ^a   Holgate, Stephen T ^b   Wardlaw, Andrew J ^a   Pavord, Ian D ^a  

^a UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TRYPTASE;

ADULT; ARTICLE; ASTHMA; BASEMENT MEMBRANE; BREATHING MUSCLE; BRONCHITIS; BRONCHUS BIOPSY; CELL INFILTRATION; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EOSINOPHIL; FEMALE; HUMAN; HUMAN TISSUE; HYPOTHESIS; IMMUNOHISTOCHEMISTRY; MALE; MAST CELL; MULTICENTER STUDY; PRIORITY JOURNAL; SMOOTH MUSCLE; T LYMPHOCYTE;

ADULT; ASTHMA; BASEMENT MEMBRANE; BIOPSY; BRONCHI; BRONCHITIS; EOSINOPHILIA; FEMALE; HUMANS; MALE; MAST CELLS; MIDDLE AGED; MUSCLE, SMOOTH; REFERENCE VALUES;

EID: 0037198418     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMoa012705     Document Type: Article

References (20)

1. Eosinophils in asthma and other allergic diseases
2. Airway hyperresponsiveness in asthma: Not just a matter of airway inflammation
3. Chronic cough: Eosinophilic bronchitis without asthma
4. Eosinophilic bronchitis: An important cause of prolonged cough
5. Eosinophilic bronchitis is an important cause of chronic cough
6. Chronic cough resembles asthma with IL-5 and granulocyte-macrophage colonystimulating factor gene expression in bronchoalveolar cells
7. Induced sputum inflammatory mediator concentrations in eosinophilic bronchitis and asthma
8. The use of induced sputum to investigate airway inflammation
9. British Thoracic Society guidelines on diagnostic flexible bronchoscopy
10. Immunohistochemistry on resin sections: A comparison of resin embedding techniques for small mucosal biopsies
11. Variation in the measurement of basement membrane thickness and inflammatory cell number in bronchial biopsies
12. Corticosteroid reversibility in COPD is related to features of asthma
13. Human mast cell and airway smooth muscle cell interactions: Implications for asthma
14. Degradation of airway neuropeptides by human lung tryptase
15. Tryptase inhibitors block allergen-induced airway and inflammatory responses in allergic sheep
16. Alpha-thrombin stimulates contraction of human bronchial rings by activation of protease-activated receptors
17. Epithelial desquamation in asthma: Artifact or pathology?
18. Mast cell numbers are increased in the smooth muscle of human sensitized isolated bronchi
19. Identification of basophils by immunohistochemistry in the airways of post-mortem cases of fatal asthma