Defective epithelial barrier function in asthma

Journal of Allergy and Clinical Immunology

Volumn 128, Issue 3, 2011, Pages

  Xiao, Chang ^a   Puddicombe, Sarah M ^a   Field, Sarah ^a   Haywood, Joel ^a   Broughton Head, Victoria ^a   Puxeddu, Ilaria ^a   Haitchi, Hans Michael ^a   Vernon Wilson, Elizabeth ^a   Sammut, David ^a   Bedke, Nicole ^a   Cremin, Catherine ^a   Sones, Jody ^a   Djukanović, Ratko ^a   Howarth, Peter H ^a   Collins, Jane E ^a   Holgate, Stephen T ^a   Monk, Phillip ^a   Davies, Donna E ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

asthma; cigarette smoke; epidermal growth factor; epithelial barrier; Tight junction

Indexed keywords

CIGARETTE SMOKE; DEXTRAN; EPIDERMAL GROWTH FACTOR;

ARTICLE; ASTHMA; BRONCHOSCOPY; BRONCHUS BIOPSY; BRONCHUS MUCOSA; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DONOR; ELECTRIC RESISTANCE; ELECTRON MICROSCOPY; ENVIRONMENTAL EXPOSURE; EPITHELIUM CELL; GOBLET CELL; HUMAN; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; PERMEABILITY BARRIER; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIGHT JUNCTION; WESTERN BLOTTING;

EID: 80052219553     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.05.038     Document Type: Article

References (47)

1. S.T. Holgate, D.E. Davies, R.M. Powell, P.H. Howarth, H.M. Haitchi, and J.W. Holloway Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms Eur Respir J 29 2007 793 803 (Pubitemid 46554630)
2. E. Steed, M.S. Balda, and K. Matter Dynamics and functions of tight junctions Trends Cell Biol 20 2010 142 149
3. J.M. Anderson, and C.M. Van Itallie Physiology and function of the tight junction Cold Spring Harb Perspect Biol 1 2009 a002584
4. J.R. Turner Intestinal mucosal barrier function in health and disease Nat Rev Immunol 9 2009 799 809
5. H.A. Thomason, A. Scothern, S. McHarg, and D.R. Garrod Desmosomes: adhesive strength and signalling in health and disease Biochem J 429 2010 419 433
6. M. Furuse Molecular basis of the core structure of tight junctions Cold Spring Harb Perspect Biol 2 2010 a002907
7. M. Cereijido, L. Gonzalez-Mariscal, and R.G. Contreras Epithelial tight junctions Am Rev Respir Dis 138 1988 S17 S21
8. P.R. Dragsten, R. Blumenthal, and J.S. Handler Membrane asymmetry in epithelia: is the tight junction a barrier to diffusion in the plasma membrane? Nature 294 1981 718 722 (Pubitemid 12174440)
9. G. van Meer, and K. Simons The function of tight junctions in maintaining differences in lipid composition between the apical and the basolateral cell surface domains of MDCK cells EMBO J 5 1986 1455 1464
10. C.N. Palmer, A.D. Irvine, A. Terron-Kwiatkowski, Y. Zhao, H. Liao, and S.P. Lee Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis Nat Genet 38 2006 441 446
11. B.A. De, N.M. Rafaels, L.Y. McGirt, A.I. Ivanov, S.N. Georas, and C. Cheadle Tight junction defects in patients with atopic dermatitis J Allergy Clin Immunol 127 2011 773 786
12. M. Heyman Gut barrier dysfunction in food allergy Eur J Gastroenterol Hepatol 17 2005 1279 1285 (Pubitemid 41830446)
13. H. Wan, H.L. Winton, C. Soeller, E.R. Tovey, D.C. Gruenert, and P.J. Thompson Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions J Clin Invest 104 1999 123 133 (Pubitemid 29534352)
14. S.M. Evans, D.I. Blyth, T. Wong, S. Sanjar, and M.R. West Decreased distribution of lung epithelial junction proteins after intratracheal antigen or lipopolysaccharide challenge: correlation with neutrophil influx and levels of BALF sE-cadherin Am J Respir Cell Mol Biol 27 2002 446 454
15. I. Tillie-Leblond, P. Gosset, R. Le Berre, A. Janin, T. Prangere, and A.B. Tonnel Keratinocyte growth factor improves alterations of lung permeability and bronchial epithelium in allergic rats Eur Respir J 30 2007 31 39 (Pubitemid 47074003)
16. W.I. de Boer, H.S. Sharma, S.M. Baelemans, H.C. Hoogsteden, B.N. Lambrecht, and G.J. Braunstahl Altered expression of epithelial junctional proteins in atopic asthma: possible role in inflammation Can J Physiol Pharmacol 86 2008 105 112 (Pubitemid 351536459)
17. M. Spears, E. Cameron, R. Chaudhuri, and N.C. Thomson Challenges of treating asthma in people who smoke Expert Rev Clin Immunol 6 2010 257 268
18. S.M. Puddicombe, C. Xiao, R. Haynes, S.A. Martin, S.T. Holgate, and D.E. Davies Epithelial barrier integrity is impaired in cultured asthmatic bronchial epithelial cells (BECs) differentiated in vitro Proc Am Thor Soc 3 2006 A424
19. C. Xiao, N. Bedke, S.T. Holgate, D.E. Davies, and S.M. Puddicombe Bronchial epithelial barrier integrity is altered in asthma but not normal subjects, independent of atopy Am J Resp Crit Care Med 175 2007 A886
20. C. Xiao, S. Field, I. Puxeddu, H.M. Haitchi, E. Vernon-Wilson, and D. Sammut Disrupted tight junctions and epithelial susceptibility in asthma - protection by an epithelial-selective EGF analogue Am J Resp Crit Care Med 177 2008 A57
21. R. Djukanovic, J.W. Wilson, C.K. Lai, S.T. Holgate, and P.H. Howarth The safety aspects of fiberoptic bronchoscopy, bronchoalveolar lavage, and endobronchial biopsy in asthma Am Rev Respir Dis 143 1991 772 777
22. K.M. Britten, P.H. Howarth, and W.R. Roche Immunohistochemistry on resin sections: a comparison of resin embedding techniques for small mucosal biopsies Biotech Histochem 68 1993 271 280 (Pubitemid 23305102)
23. F. Bucchieri, S.M. Puddicombe, J.L. Lordan, A. Richter, D. Buchanan, and S.J. Wilson Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis Am J Respir Cell Mol Biol 27 2002 179 185 (Pubitemid 34780797)
24. T.E. Gray, K. Guzman, C.W. Davis, L.H. Abdullah, and P. Nettesheim Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells Am J Respir Cell Mol Biol 14 1996 104 112 (Pubitemid 126443096)
25. C. Ehrhardt, C. Kneuer, J. Fiegel, J. Hanes, U.F. Schaefer, and K.J. Kim Influence of apical fluid volume on the development of functional intercellular junctions in the human epithelial cell line 16HBE14o-: implications for the use of this cell line as an in vitro model for bronchial drug absorption studies Cell Tissue Res 308 2002 391 400 (Pubitemid 34666965)
26. D.E. Davies, R. Polosa, S.M. Puddicombe, A. Richter, and S.T. Holgate The epidermal growth factor receptor and its ligand family: their potential role in repair and remodelling in asthma Allergy 54 1999 771 783 (Pubitemid 29402159)
27. S. Basuroy, A. Seth, B. Elias, A.P. Naren, and R. Rao MAPK interacts with occludin and mediates EGF-induced prevention of tight junction disruption by hydrogen peroxide Biochem J 393 2006 69 77 (Pubitemid 43049303)
28. M.H. Boskabady, and P.D. Snashall Enhanced muscarinic receptor blockade with atropine in the asthmatic tracheobronchial tree. Evidence for increased drug delivery Am Rev Respir Dis 145 1992 756 761
29. M. Ahdieh, T. Vandenbos, and A. Youakim Lung epithelial barrier function and wound healing are decreased by IL-4 and IL-13 and enhanced by IFN-gamma Am J Physiol Cell Physiol 281 2001 C2029 C2038
30. S. Prasad, R. Mingrino, K. Kaukinen, K.L. Hayes, R.M. Powell, and T.T. MacDonald Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells Lab Invest 85 2005 1139 1162 (Pubitemid 43073987)
31. M. Terakado, Y. Gon, A. Sekiyama, I. Takeshita, Y. Kozu, and K. Matsumoto The Rac1/JNK pathway is critical for EGFR-dependent barrier formation in human airway epithelial cells Am J Physiol Lung Cell Mol Physiol 300 2011 L56 L63
32. R. Polosa, G. Prosperini, S.H. Leir, S.T. Holgate, P.M. Lackie, and D.E. Davies Expression of c-erbB receptors and ligands in human bronchial mucosa Am J Respir Cell Mol Biol 20 1999 914 923 (Pubitemid 129540850)
33. R.A. O'Donnell, A. Richter, J. Ward, G. Angco, A. Mehta, and K. Rousseau Expression of ErbB receptors and mucins in the airways of long-term current smokers Thorax 59 2004 1032 1040 (Pubitemid 39573921)
34. P.D. Vermeer, L.A. Einwalter, T.O. Moninger, T. Rokhlina, J.A. Kern, and J. Zabner Segregation of receptor and ligand regulates activation of epithelial growth factor receptor Nature 422 2003 322 326 (Pubitemid 36378360)
35. M. Bruewer, S. Samarin, and A. Nusrat Inflammatory bowel disease and the apical junctional complex Ann N Y Acad Sci 1072 2006 242 252 (Pubitemid 44448457)
36. A. Sinha, J. Nightingale, K.P. West, J. Berlanga-Acosta, and R.J. Playford Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis N Engl J Med 349 2003 350 357 (Pubitemid 36886241)
37. R.J. Farrell Epidermal growth factor for ulcerative colitis N Engl J Med 349 2003 395 397 (Pubitemid 36886247)
38. T. Hayashi, and S. Sakamoto Radioimmunoassay of human epidermal growth factor-hEGF levels in human body fluids J Pharmacobiodyn 11 1988 146 151
39. J.W. Sweetenham, D.E. Davies, S. Warnes, and P. Alexander Urinary epidermal growth factor (hEGF) levels in patients with carcinomas of the breast, colon and rectum Br J Cancer 62 1990 459 461 (Pubitemid 20292847)
40. G.E. Oxford, L. Tayari, M.D. Barfoot, A.B. Peck, Y. Tanaka, and M.G. Humphreys-Beher Salivary EGF levels reduced in diabetic patients J Diabetes Complications 14 2000 140 145
41. L. Ma, W.P. Wang, J.Y. Chow, S.T. Yuen, and C.H. Cho Reduction of EGF is associated with the delay of ulcer healing by cigarette smoking Am J Physiol Gastrointest Liver Physiol 278 2000 G10 G17
42. C.E. Shin, R.A. Falcone Jr., L. Stuart, C.R. Erwin, and B.W. Warner Diminished epidermal growth factor levels in infants with necrotizing enterocolitis J Pediatr Surg 35 2000 173 176
43. R. Djukanovic, J.W. Wilson, C.K. Lai, S.T. Holgate, and P.H. Howarth The safety aspects of fiberoptic bronchoscopy, bronchoalveolar lavage, and endobronchial biopsy in asthma Am Rev Respir Dis 143 1991 772 777
44. J. Bousquet Global Initiative for Asthma (GINA) and its objectives Clin Exp Allergy 30 2000 2 5 (Pubitemid 30341369)
45. K.M. Britten, P.H. Howarth, and W.R. Roche Immunohistochemistry on resin sections: a comparison of resin embedding techniques for small mucosal biopsies Biotech Histochem 68 1993 271 280 (Pubitemid 23305102)
46. F. Bucchieri, S.M. Puddicombe, J.L. Lordan, A. Richter, D. Buchanan, and S.J. Wilson Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis Am J Respir Cell Mol Biol 27 2002 179 185 (Pubitemid 34780797)
47. T.E. Gray, K. Guzman, C.W. Davis, L.H. Abdullah, and P. Nettesheim Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells Am J Respir Cell Mol Biol 14 1996 104 112 (Pubitemid 126443096)