Airway epithelial cells release MIP-3α/CCL20 in response to cytokines and ambient particulate matter

American Journal of Respiratory Cell and Molecular Biology

Volumn 28, Issue 6, 2003, Pages 648-654

  Reibman, Joan ^a   Hsu, Yanshen ^b   Chen, Lung Chi ^b   Bleck, Bertram ^b   Gordon, Terry ^b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CHEMOKINE; CHEMOKINE RECEPTOR CCR6; CYTOKINE; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; LIGAND; MACROPHAGE INHIBITORY PROTEIN 3ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLERGIC DISEASE; ARTICLE; CELL CULTURE; CELL MATURATION; CELL MIGRATION; CELL SIZE; DENDRITIC CELL; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MEDIATOR RELEASE; PARTICULATE MATTER; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; STEM CELL; STIMULUS RESPONSE; SYNTHESIS; UPREGULATION;

AIR POLLUTANTS; BRONCHI; CELLS, CULTURED; CHEMOKINES, CC; CYTOKINES; DENDRITIC CELLS; ENZYME INHIBITORS; EPITHELIAL CELLS; FLAVONOIDS; HUMANS; IMIDAZOLES; MACROPHAGE INFLAMMATORY PROTEINS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PARTICLE SIZE; PYRIDINES; RECEPTORS, CHEMOKINE; RESPIRATORY MUCOSA; RNA, MESSENGER;

EID: 0038798012     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2002-0095OC     Document Type: Article

References (44)

1. Lanzavecchia, A., and F. Sallusto. 2001. Regulation of T cell immunity by dendritic cells. Cell 106:263-266.
2. Lambrecht, B. N. 2001. Allergen uptake and presentation by dendritic cells. Curr. Opin. Allergy Clin. Immunol. 1:51-59.
3. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392:245-252.
4. Liu. Y. J. 2001. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106:259-262.
5. Caux, C., B. Vanbervliet, C. Massacrier, S. Ait-Yahia, C. Vaure. K. Chemin, MC Dieu-Nosjean And, and A. Vicari. 2002. Regulation of dendritic cell recruitment by chemokines. Transplantation 73(1 Suppl):S7-S11.
6. Mackay, C. R. 2001. Chemokines: immunology's high impact factors. Nat. Immunol. 2:95-101.
7. Lukacs, N. W. 2001. Role of chemokines in the pathogenesis of asthma. Nature Rev. Immunol. 1:108-116.
8. Zlotnik, A., and O. Yoshie. 2000. Chemokines: a new classification system and their role in immunity. Immunity 12:121-127.
9. Hromas, R., P. W. Gray, D. Chantry, R. Godiska, M. Krathwohl, K. Fife, G. I. Bell, J. Takeda, S. Aronica, M. Gordon, S. Cooper, H. E. Broxmeyer, and M. J. Klemsz. 1997. Cloning and characterization of exodus, a novel beta-chemokine. Blood 89:3315-3322.
10. Rossi, D. L., A. P. Vicari, K. Franz-Bacon. T. K. McClanahan, and A. Zlotnik. 1997. Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta. J. Immunol. 158:1033-1036.
11. Hieshima, K. T. Imai, G. Opdenakker, J. Van Damme, J. Kusuda, H. Tei, Y. Sakaki, K. Takatsuki, R. Miura, O. Yoshie, and H. Nomiyama. 1997. Molecular cloning of a novel human CC chemokine liver and activation-regulated chemokine (LARC) expressed in liver: chemotactic activity for lymphocytes and gene localization on chromosome 2. J. Biol. Chem. 272:5846-5853.
12. Greaves, D. R. W. Wang, D. J. Dairaghi, M. C. Dieu, B. Saint-Vis, K. Franz-Bacon, D. Rossi, C. Caux, T. McClanahan, S. Gordon, A. Zlotnik, and T. J. Schall. 1997. CCR6. a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells. J. Exp. Med. 186:837-844.
13. Ebert, L. M., and S. R. McColl. 2002. Up-regulation of CCR5 and CCR6 on distinct subpopulations of antigen-activated CD4+ T lymphocytes. J. Immunol. 168:65-72.
14. Krzysiek, R., E. A. Lefevre, J. Bernard, A. Foussat, P. Galanaud, F. Louache, and Y. Richard. 2000. Regulation of CCR6 chemokine receptor expression and responsiveness to macrophage inflammatory protein-3alpha/CCL20 in human B cells. Blood 96:2338-2345.
15. Tanaka, Y., T. Imai, M. Baba, I. Ishikawa, M. Uehira, H. Nomiyama, and O. Yoshie. 1999. Selective expression of liver and activation-regulated chemokine (LARC) in intestinal epithelium in mice and humans. Eur. J. Immunol. 29:633-642.
16. Homey, B., M. C. Dieu-Nosjean, A. Wiesenborn, C. Massacrier, J. J. Pin, E. Oldham, D. Carton, M. E. Buchanan, A. Muller, R. deWaal Malefyt, G. Deng, R. Orozco, T. Ruzicka, P. Lehmann, S. Lebecque, C. Caux, and A. Zlotnik. 2000. Up-regulation of macrophage inflammatory protein-3 alpha/CCL20 and CC chemokine receptor 6 in psoriasis. J. Immunol. 164:6621-6632.
17. Izadpanah, A., M. B. Dwinell, L. Eckmann, N. M. Varki, and M. F. Kagnoff. 2001. Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity. Am. J. Physiol. Gastrointest. Liver Physiol. 280:G710-G719.
18. Casamayor-Palleja, M., P. Mondiere, A. Amara. C. Bella, M. C. Dieu-Nosjean, C. Caux, and T. Defrance. 2001. Expression of macrophage inflammatory protein-3alpha, stromal cell-derived factor-1, and B-cell-attracting chemokine-1 identifies the tonsil crypt as an attractive site for B cells. Blood 97:3992-3994.
19. Jahnsen, F. L., E. D. Moloney, T. Hogan, J. W. Upham, C. M. Burke, and P. G. Holt. 2001. Rapid dendritic cell recruitment to the bronchial mucosa of patients with atopic asthma in response to local allergen challenge. Thorax 56:823-826.
20. Holt, P. G., and P. A. Stumbles. 2000. Characterization of dendritic cell populations in the respiratory tract. J. Aerosol Med. 13:361-367.
21. Stumbles, P. A.. D. H. Strickland, C. L. Pimm, S. F. Proksch, A. M. Marsh, A. S. McWilliam. A. Bosco. I. Tobagus, J. A. Thomas, S. Napoli, A. E. Proudfoot, T. N. Wells, and P. G. Holt. 2001. Regulation of dendritic cell recruitment into resting and inflamed airway epithelium: use of alternative cbemokine receptors as a function of inducing stimulus. J. Immunol. 167:228-234.
22. Lukacs, N. W., D. M. Prosser, M. Wiekowski, S. A. Lira, and D. N. Cook. 2001. Requirement for the chemokine receptor CCR6 in allergic pulmonary inflammation. J. Exp. Med. 194:551-555.
23. Holt, P. G., M. A. Schon-Hegrad, J. Oliver. B. J. Holt, and P. G. McMenamin. 1990. A contiguous network of dendritic antigen-presenting cells within the respiratory epithelium. Int. Arch. Allergy Appl. Immunol. 91:155-159.
24. Romagnani, S. 2002. Cytokines and chemoattractants in allergic inflammation. Mol. Immunol. 38:881-885.
25. Reibman, J., Y. Hsu, L. Chen, A. Kumar. S. W., W. Choy, A. Talbot, and T. Gordon. 2002. Size-fractions of ambient particulate matter induce granulocyte-macrophage colony stimulating factor in human bronchial epithelial cells by mitogen activated protein kinase pathways. Am. J. Respir. Cell Mol Biol. 27:455-462.
26. Reibman, J., A. T. Talbot, Y. Hsu. G. Ou, J. Jover. D. Nilsen, and M. H. Pillinger. 2000. Regulation of expression of granulocyte-macrophage colony-stimulating factor in human bronchial epithelial cells: roles of protein kinase C and mitogen-activated protein kinases. J. Immunol. 165:1618-1625.
27. Chang, L., and M. Karin. 2001. Mammalian MAP kinase signalling cascades. Nature 410:37-40.
28. Perez-Canadillas, J. M., A. Zaballos, J. Gutierrez, R. Varona. F. Roncal, J. P. Albar, G. Marquez, and M. Bruix. 2001. NMR solution structure of murine CCL20/MIP-3alpha, a chemokine that specifically chemoattracts immature dendritic cells and lymphocytes through its highly specific interaction with the beta-chemokine receptor CCR6. J. Biol. Chem. 276:28372-28379.
29. Dieu, M. C., B. Vanbervliet, A. Vicari, J. M. Bridon, E. Oldham, S. AitYahia. F. Briere, A. Zlotnik, S. Lebecque, and C. Caux. 1998. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J. Exp. Med. 188:373-386.
30. Charbonnier. A. S., N. Kohrgruber, E. Kriehuber. G. Stingl, A. Rot. and D. Maurer. 1999. Macrophage inflammatory protein 3alpha is involved in the constitutive trafficking of epidermal Langerhans cells. J. Exp. Med. 190:1755-1768.
31. Dieu-Nosjean, M. C., C. Massacrier, B. Homey, B. Vanbervliet, J. J. Pin, A. Vicari, S. Lebecque, C. Dezutter-Dambuyant, D. Schmitt, A. Zlotnik, and C. Caux. 2000. Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors. J. Exp. Med. 192:705-718.
32. Nakayama, T., R. Fujisawa, H. Yamada, T. Horikawa. H. Kawasaki, K. Hieshima, D. Izawa, S. Fujiie, T. Tezuka, and O. Yoshie. 2001. Inducible expression of a CC chemokine liver- and activation-regulated chemokine (LARC)/macrophage inflammatory protein (MIP)-3 alpha/CCL20 by epidermal keratinocytes and its role in atopic dermatitis. Int. Immunol. 13:95-103.
33. Tohyama, M., Y. Shirakara, K. Yamasaki, K. Sayama, and K. Hashimoto. 2001. Differentiated keratinocytes are responsible for TNF-alpha regulated production of macrophage inflammatory protein 3alpha/CCL20. a potent chemokine for Langerhans cells. J. Dermatol. Sci. 27:130-139.
34. Scapini, P., C. Laudanna, C. Pinardi, P. Allavena. A. Mantovani, S. Sozzani. and M. A. Cassatella. 2001. Neutrophils produce biologically active macrophage inflammatory protein-3alpha (MIP-3alpha)/CCL20 and MIP-3beta/CCL19. Eur. J. Immunol. 31:1981-1988.
35. Dabbagh, K., K. Takeyama, H. M. Lee. I. F. Ueki, J. A. Lausier, and J. A. Nadel. 1999. IL-4 induces mucin gene expression and goblet ceil metaplasia in vitro and in vivo. J. Immunol. 162:6233-6237.
36. Heinzmann, A., X. Q. Mao, M. Akaiwa. R. T. Kreomer, P. S. Gao, K. Ohshima, R. Umeshita, Y. Abe, S. Braun, T. Yamashita, M. H. Roberts, R. Sugimoto. K. Arima, Y. Arinobu, B. Yu, S. Kruse, T. Enomoto, Y. Dake, M. Kawai, S. Shimazu, S. Sasaki, C. N. Adra, M. Kitaichi, H. Inoue, K. Yamauchi, N. Tomichi, F. Kurimoto, N. Hamasaki, J. M Hopkin, K. Izuhara, T. Shirakawa, and K. A. Deichmann. 2000. Genetic variants of IL-13 signalling and human asthma and atopy. Hum. Mol. Genet. 9:549-559.
37. Romagnani, S. 2001. T-cell responses in allergy and asthma. Curr. Opin. Allergy Clin. Immunol. 1:73-78.
38. Diaz-Sanchez, D. 2000. Pollution and the immune response: atopic diseases: are we too dirty or too clean? Immunology 101:11-18.
39. Laden, F., L. M. Neas, D. W. Dockery, and J. Schwartz. 2000. Association of fine particulate matter from different sources with daily mortality in six U.S. cities. Environ. Health Perspect. 108:941-947.
40. Fujiie, S., K. Hieshima, D. Izawa, T. Nakayama, R. Fujisawa, H. Ohyanagi, and O. Yoshie. 2001. Proinflammatory cytokines induce liver and activation-regulated chemokine/macrophage inflammatory protein-3alpha/CCL20 in mucosal epithelial cells through NF-kappaB. Int. Immunol. 13:1255-1263.
41. Sugita, S., T. Kohno, K. Yamamoto, Y. Imaizumi, H. Nakajima, T. Ishimaru, and T. Matsuyama. 2002. Induction of macrophage-inflammatory protein-3alpha gene expression by TNF-dependent NF-kappaB activation. J. Immunol. 168:5621-5628.
42. Jiang, H., M. B. Harris, and P. Rothman. 2000. IL-4/IL-13 signaling beyond JAK/STAT. J. Allergy Clin. Immunol. 105:1063-1070.
43. Laporte, J. C., P. E. Moore, S. Baraldo, M. H. Jouvin, T. L. Church, I. N. Schwartzman, R. A. Panettieri, Jr., J. P. Kinet, and S. A. Shore. 2001. Direct effects of interleukin-13 on signaling pathways for physiological responses in cultured human airway smooth muscle cells. Am. J. Respir. Crit. Care Med. 164:141-148.
44. Hirst. S. J., M. P. Hatlsworth, Q. Peng, and T. H. Lee. 2002. Selective induction of eotaxin release by interleukin-13 or interleukin- 4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor alpha-chain. Am. J. Respir. Crit. Care Med. 165:1161-1171.