Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 300, Issue 3, 2011, Pages

  le Cras, Timothy D ^a   Acciani, Thomas H ^a   Mushaben, Elizabeth M ^a   Kramer, Elizabeth L ^a   Pastura, Patricia A ^a   Hardie, William D ^a   Korfhagen, Thomas R ^a   Sivaprasad, Umasundari ^a   Ericksen, Mark ^a   Gibson, Aaron M ^a   Holtzman, Michael J ^b   Whitsett, Jeffrey A ^a   Hershey, Gurjit Khurana K ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Airway hyperresponsiveness; Airway smooth muscle; Allergic asthma; House dust mite; Pulmonary inflammation

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; METHACHOLINE;

AIRWAY HYPERREACTIVITY; AIRWAY REMODELING; ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; DERMATOPHAGOIDES; GOBLET CELL; INFLAMMATORY CELL; LUNG ALVEOLUS EPITHELIUM; METAPLASIA; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; SENSITIZATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE;

AIRWAY REMODELING; ANIMALS; ASTHMA; BRONCHIAL HYPERREACTIVITY; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; EPITHELIAL CELLS; GOBLET CELLS; INFLAMMATION; LUNG; METAPLASIA; MICE; MUSCLE, SMOOTH; PYROGLYPHIDAE; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 79955047047     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00346.2010     Document Type: Article

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