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Volumn 113, Issue 4, 2004, Pages 551-560

Inhibition of airway remodeling in IL-5-deficient mice

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; COLLAGEN TYPE 3; COLLAGEN TYPE 5; INTEGRIN; INTERLEUKIN 5; MAJOR BASIC PROTEIN; OVALBUMIN; TRANSFORMING GROWTH FACTOR BETA; ALPHAVBETA6 INTEGRIN; TUMOR ANTIGEN;

EID: 85047693288     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI19133     Document Type: Article
Times cited : (357)

References (34)
  • 2
    • 0036014818 scopus 로고    scopus 로고
    • Fast flowing eosinophils: Signals for stopping and stepping out of blood vessels
    • Broide, D. 2002. Fast flowing eosinophils: signals for stopping and stepping out of blood vessels. Am. J. Respir. Cell Mol. Biol. 26:637-640.
    • (2002) Am. J. Respir. Cell Mol. Biol. , vol.26 , pp. 637-640
    • Broide, D.1
  • 3
    • 0023879839 scopus 로고
    • Recombinant human interleukin 5 is a selective activator of human eosinophil function
    • Lopez, A.F., et al. 1988. Recombinant human interleukin 5 is a selective activator of human eosinophil function. J. Exp. Med. 167:219-224.
    • (1988) J. Exp. Med. , vol.167 , pp. 219-224
    • Lopez, A.F.1
  • 4
    • 0030028768 scopus 로고    scopus 로고
    • Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model
    • Foster, P.S., Hogan, S.P., Ramsay, A.J., Matthaei, K.I., and Young, I.G. 1996. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J. Exp. Med. 183:195-201.
    • (1996) J. Exp. Med. , vol.183 , pp. 195-201
    • Foster, P.S.1    Hogan, S.P.2    Ramsay, A.J.3    Matthaei, K.I.4    Young, I.G.5
  • 5
    • 17444454662 scopus 로고    scopus 로고
    • Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma
    • Lee, J.J., et al. 1997. Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma. J. Exp. Med. 185:2143-2156.
    • (1997) J. Exp. Med. , vol.185 , pp. 2143-2156
    • Lee, J.J.1
  • 6
    • 0030969430 scopus 로고    scopus 로고
    • Anti-interleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization
    • Hamelmann, E., et al. 1997. Anti-interleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization. Am. J. Respir. Crit. Care Med. 155:819-825.
    • (1997) Am. J. Respir. Crit. Care Med. , vol.155 , pp. 819-825
    • Hamelmann, E.1
  • 7
    • 0032873662 scopus 로고    scopus 로고
    • Anti-interleukin 5 but not anti-IgE prevents airway inflammation and airway hyperresponsiveness
    • Hamelmann, E., et al. 1999. Anti-interleukin 5 but not anti-IgE prevents airway inflammation and airway hyperresponsiveness. Am. J. Respir. Crit. Care Med. 160:934-941.
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , pp. 934-941
    • Hamelmann, E.1
  • 8
    • 0030068235 scopus 로고    scopus 로고
    • Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity
    • Corry, D, et al. 1996. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J. Exp. Med. 183:109-117.
    • (1996) J. Exp. Med. , vol.183 , pp. 109-117
    • Corry, D.1
  • 9
    • 0037443649 scopus 로고    scopus 로고
    • A causative relationship exists between eosinophils and the development of allergic pulmonary pathologies in the mouse
    • Shen, H.H., et al. 2003. A causative relationship exists between eosinophils and the development of allergic pulmonary pathologies in the mouse. J. Immunol. 170:3296-3305.
    • (2003) J. Immunol. , vol.170 , pp. 3296-3305
    • Shen, H.H.1
  • 10
    • 0037013925 scopus 로고    scopus 로고
    • Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma
    • Mattes, J., et al. 2002. Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma. J. Exp. Med. 195:1433-1444.
    • (2002) J. Exp. Med. , vol.195 , pp. 1433-1444
    • Mattes, J.1
  • 11
    • 0026610142 scopus 로고
    • Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma
    • Robinson, D.S., et al. 1992. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med. 326:298-304.
    • (1992) N. Engl. J. Med. , vol.326 , pp. 298-304
    • Robinson, D.S.1
  • 12
    • 0026482042 scopus 로고
    • Eosinophils express interleukin 5 and granulocyte macrophage-colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics
    • Broide, D.H., Paine, M.M., and Firestein, G.S. 1992. Eosinophils express interleukin 5 and granulocyte macrophage-colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics. J. Clin. Invest. 90:1414-1424.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1414-1424
    • Broide, D.H.1    Paine, M.M.2    Firestein, G.S.3
  • 13
    • 0028804244 scopus 로고
    • Eosinophilic inflammation is associated with elevation of interleukin-5 in the airways of patients with spontaneous symptomatic asthma
    • Sur, S., Gleich, GJ., Swanson, M.C., Bartemes, K.R., and Broide, D.H. 1995. Eosinophilic inflammation is associated with elevation of interleukin-5 in the airways of patients with spontaneous symptomatic asthma. J. Allergy Clin. Immunol. 96:661-668.
    • (1995) J. Allergy Clin. Immunol. , vol.96 , pp. 661-668
    • Sur, S.1    Gleich, G.J.2    Swanson, M.C.3    Bartemes, K.R.4    Broide, D.H.5
  • 14
    • 15144358845 scopus 로고    scopus 로고
    • Effect of inhaled interleukin-5 on airway hyperreactivity and eosinophilia in asthmatics
    • Shi, H.Z., et al. 1998. Effect of inhaled interleukin-5 on airway hyperreactivity and eosinophilia in asthmatics. Am. J. Respir. Crit. Care Med. 157:204-209.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , pp. 204-209
    • Shi, H.Z.1
  • 15
    • 6644229440 scopus 로고    scopus 로고
    • Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
    • Leckie, M.J., et al. 2000. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet. 356:2144-2148.
    • (2000) Lancet , vol.356 , pp. 2144-2148
    • Leckie, M.J.1
  • 16
    • 0037438409 scopus 로고    scopus 로고
    • Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway
    • Flood-Page, P.T., Menzies-Gow, A.N., Kay, A.B., and Robinson, D.S. 2003. Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway. Am. J. Respir. Crit. Care Med. 167:199-204.
    • (2003) Am. J. Respir. Crit. Care Med. , vol.167 , pp. 199-204
    • Flood-Page, P.T.1    Menzies-Gow, A.N.2    Kay, A.B.3    Robinson, D.S.4
  • 18
    • 0024505353 scopus 로고
    • Subepithelial fibrosis in the bronchi of asthmatics
    • Roche, W.R., Beasley, R., Williams, J., and Holgate, S.T. 1989. Subepithelial fibrosis in the bronchi of asthmatics. Lancet. 1:520-524.
    • (1989) Lancet , vol.1 , pp. 520-524
    • Roche, W.R.1    Beasley, R.2    Williams, J.3    Holgate, S.T.4
  • 19
    • 0035423346 scopus 로고    scopus 로고
    • Airway smooth muscle cell proliferation is increased in asthma
    • Johnson, P.R., et al. 2001. Airway smooth muscle cell proliferation is increased in asthma. Am. J. Resp. Crit. Care. Med. 164:474-477.
    • (2001) Am. J. Resp. Crit. Care. Med. , vol.164 , pp. 474-477
    • Johnson, P.R.1
  • 20
    • 0030236307 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation
    • Ohno, I., et al. 1996. Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation. Am. J. Respir. Cell Mol. Biol. 15:404-409.
    • (1996) Am. J. Respir. Cell Mol. Biol. , vol.15 , pp. 404-409
    • Ohno, I.1
  • 21
    • 0031226757 scopus 로고    scopus 로고
    • Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma
    • Minshall, E.M., et al. 1997. Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma. Am. J. Respir. Cell Mol. Biol. 7:326-333.
    • (1997) Am. J. Respir. Cell Mol. Biol. , vol.7 , pp. 326-333
    • Minshall, E.M.1
  • 22
    • 0032526349 scopus 로고    scopus 로고
    • IL-4-dependent regulation of TGF-alpha and TGF-beta 1 expression in human eosinophils
    • Elovic, A.E., et al. 1998. IL-4-dependent regulation of TGF-alpha and TGF-beta 1 expression in human eosinophils. J. Immunol. 160:6121-6127.
    • (1998) J. Immunol. , vol.160 , pp. 6121-6127
    • Elovic, A.E.1
  • 23
    • 0033788442 scopus 로고    scopus 로고
    • Activation and transforming growth factor-beta production in eosinophils by hyaluronan
    • Ohkawara, Y., et al. 2000. Activation and transforming growth factor-beta production in eosinophils by hyaluronan. Am. J. Respir. Cell Mol. Biol. 23:444-451.
    • (2000) Am. J. Respir. Cell Mol. Biol. , vol.23 , pp. 444-451
    • Ohkawara, Y.1
  • 24
    • 0142210354 scopus 로고    scopus 로고
    • Accumulation of peribronchial mast cells in a mouse model of ovalbumin allergen induced chronic airway inflammation: Modulation by immunostimulatory DNA sequences
    • Ikeda, R.K., et al. 2003. Accumulation of peribronchial mast cells in a mouse model of ovalbumin allergen induced chronic airway inflammation: modulation by immunostimulatory DNA sequences. J. Immunol. 171:4860-4867.
    • (2003) J. Immunol. , vol.171 , pp. 4860-4867
    • Ikeda, R.K.1
  • 25
    • 0037783483 scopus 로고    scopus 로고
    • Resolution of airway inflammation following OVA inhalation: Comparison of ISS DNA and corticosteroids
    • Ikeda, R.K., et al. 2003. Resolution of airway inflammation following OVA inhalation: comparison of ISS DNA and corticosteroids. Am. J. Resp. Cell Mol. Biol. 28:655-663.
    • (2003) Am. J. Resp. Cell Mol. Biol. , vol.28 , pp. 655-663
    • Ikeda, R.K.1
  • 26
    • 0035903306 scopus 로고    scopus 로고
    • Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1)
    • Lee, C.G., et al. 2001. Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). J. Exp. Med. 194:809-821.
    • (2001) J. Exp. Med. , vol.194 , pp. 809-821
    • Lee, C.G.1
  • 27
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in human disease
    • Blobe, G.C., Schiemann, W.P., and Lodish, H.F. 2000. Role of transforming growth factor beta in human disease. New. Engl. J. Med. 342:1350-1358.
    • (2000) New. Engl. J. Med. , vol.342 , pp. 1350-1358
    • Blobe, G.C.1    Schiemann, W.P.2    Lodish, H.F.3
  • 28
    • 0033524949 scopus 로고    scopus 로고
    • The integrin αVβ6 binds and activates latent TGF-β1: A mechanism for regulating pulmonary inflammation and fibrosis
    • Munger, J.S., et al. 1999. The integrin αVβ6 binds and activates latent TGF-β1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell. 96:319-328.
    • (1999) Cell , vol.96 , pp. 319-328
    • Munger, J.S.1
  • 29
    • 15844376477 scopus 로고    scopus 로고
    • Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin
    • Huang, X.Z., et al. 1996. Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin. J. Cell Biol. 133:921-928
    • (1996) J. Cell Biol. , vol.133 , pp. 921-928
    • Huang, X.Z.1
  • 30
    • 0028978232 scopus 로고
    • Expression of the β6 integrin subunit in development, neoplasia, and tissue repair suggests a role in epithelial remodeling
    • Breuss, J.M., et al. 1995. Expression of the β6 integrin subunit in development, neoplasia, and tissue repair suggests a role in epithelial remodeling. J. Cell Sci. 108:2241-2251.
    • (1995) J. Cell Sci. , vol.108 , pp. 2241-2251
    • Breuss, J.M.1
  • 31
    • 0033840582 scopus 로고    scopus 로고
    • Airway subepithelial fibrosis in a murine model of atopic asthma: Suppression by dexamethasone or anti-interleukin-5 antibody
    • Blyth, D.I., Wharton, T.F., Pedrick, M.S., Savage, T.J., and Sanjar, S. 2000. Airway subepithelial fibrosis in a murine model of atopic asthma: suppression by dexamethasone or anti-interleukin-5 antibody. Am. J. Respir. Cell Mol. Biol. 23:241-246.
    • (2000) Am. J. Respir. Cell Mol. Biol. , vol.23 , pp. 241-246
    • Blyth, D.I.1    Wharton, T.F.2    Pedrick, M.S.3    Savage, T.J.4    Sanjar, S.5
  • 32
    • 0034079382 scopus 로고    scopus 로고
    • Dissociation of inflammatory and epithelial responses in a murine model of chronic asthma
    • Foster, P.S., et al. 2000. Dissociation of inflammatory and epithelial responses in a murine model of chronic asthma. Lab. Invest. 80:655-662.
    • (2000) Lab. Invest. , vol.80 , pp. 655-662
    • Foster, P.S.1
  • 33
    • 0037108493 scopus 로고    scopus 로고
    • The relationship between allergen-induced tissue eosinophilia and markers of repair and remodeling in human atopic skin
    • Phipps, S., et al. 2002. The relationship between allergen-induced tissue eosinophilia and markers of repair and remodeling in human atopic skin. J. Immunol. 169:4604-4612.
    • (2002) J. Immunol. , vol.169 , pp. 4604-4612
    • Phipps, S.1
  • 34
    • 85047693849 scopus 로고    scopus 로고
    • Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
    • doi:10.1J72/JCI200317974
    • Flood-Page, P., et al. 2003. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J. Clin. Invest. 112:1029-1036. doi:10.1J72/JCI200317974.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1029-1036
    • Flood-Page, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.