Wound-induced ATP release and EGF receptor activation in epithelial cell

Journal of Cell Science

Volumn 120, Issue 5, 2007, Pages 815-825

  Yin, Jia ^a   Xu, Keping ^a   Zhang, Jing ^a   Kumar, Ashok ^a   Yu, Fu Shin X ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

ATP; Cell migration; EGFR; HB EGF; Purinoceptor; Wound healing

Indexed keywords

ADAM PROTEIN; ADENOSINE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; EPIDERMAL GROWTH FACTOR RECEPTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PURINE P2Y RECEPTOR;

ARTICLE; BRONCHUS MUCOSA; CELL LINE; CELL MIGRATION; CELLULAR STRESS RESPONSE; CELLULAR STRESS SIGNAL; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA INJURY; ENZYME ACTIVATION; ENZYME RELEASE; EPITHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; WOUND CLOSURE; WOUND HEALING;

ADAM PROTEINS; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BLOTTING, WESTERN; CALCIUM; CELL LINE; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 34047114821     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.03389     Document Type: Article

References (49)

1. Agteresch, H. J., Dagnelie, P. C., van der Gaast, A., Stijnen, T. and Wilson, J. H. (2000). Randomized clinical trial of adenosine 5′-triphosphate in patients with advanced non-small-cell lung cancer. J. Natl. Cancer Inst. 92, 321-328.
2. Agteresch, H. J., Rietveld, T., Kerkhofs, L. G., van den Berg, J. W., Wilson, J. H. and Dagnelie, P. C. (2002). Beneficial effects of adenosine triphosphate on nutritional status in advanced lung cancer patients: a randomized clinical trial. J. Clin. Oncol. 20, 371-378.
3. Ahmad, S., Ahmad, A., McConville, G., Schneider, B. K., Allen, C. B., Manzer, R., Mason, R. J. and White, C. W. (2005). Lung epithelial cells release ATP during ozone exposure: signaling for cell survival. Free Radic. Biol. Med. 39, 213-226.
4. Araki-Sasaki, K., Ohashi, Y., Sasabe, T., Hayashi, K., Watanabe, H., Tano, Y. and Handa, H. (1995). An SV40-immortalized human corneal epithelial cell line and its characterization. Invest. Ophthalmol. Vis. Sci. 36, 614-621.
5. Blobel, C. P. (2002). Functional and biochemical characterization of ADAMs and their predicted role in protein ectodomain shedding. Inflamm. Res. 51, 83-84.
6. Blobel, C. P. (2005). ADAMs: key components in EGFR signalling and development. Nat. Rev. Mol. Cell Biol. 6, 32-43.
7. Block, E. R., Matela, A. R., SundarRaj, N., Iszkula, E. R. and Klarlund, J. K. (2004). Wounding induces motility in sheets of corneal epithelial cells through loss of spatial constraints: role of heparin-binding epidermal growth factor-like growth factor signaling. J. Biol. Chem. 279, 24307-24312.
8. Brunschweiger, A. and Muller, C. E. (2006). P2 receptors activated by uracil nucleotides - an update. Curr. Med. Chem. 13, 289-312.
9. Chandrasekher, G. and Bazan, H. E. (1999). Corneal epithelial wound healing increases the expression but not long lasting activation of the p85alpha subunit of phosphatidylinositol-3 kinase. Curr. Eye Res. 18, 168-176.
10. Chandrasekher, G., Kakazu, A. H. and Bazan, H. E. (2001). HGF- and KGF-induced activation of PI-3K/p70 s6 kinase pathway in corneal epithelial cells: its relevance in wound healing. Exp. Eye Res. 73, 191-202.
11. Dethlefsen, S. M., Raab, G., Moses, M. A., Adam, R. M., Klagsbrun, M. and Freeman, M. R. (1998). Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin-binding EGF-like growth factor independently of protein kinase C. J. Cell. Biochem. 69, 143-153.
12. Gechtman, Z., Alonso, J. L., Raab, G., Ingber, D. E. and Klagsbrun, M. (1999). The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading. J. Biol. Chem. 274, 28828-28835.
13. Glading, A., Chang, P., Lauffenburger, D. A. and Wells, A. (2000). Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway. J. Biol. Chem. 275, 2390-2398.
14. Goishi, K., Higashiyama, S, Klagsbrun, M., Nakano, N., Umata, T., Ishikawa, M., Mekada, E. and Taniguchi, N. (1995). Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity. Mol. Biol. Cell 6, 967-980.
15. Higashiyama, S. and Nanba, D. (2005). ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk. Biochim. Biophys. Acta 1751, 110-117.
16. Higashiyama, S., Iwamoto, R., Goishi, K., Raab, G., Taniguchi, N, Klagsbrun, M. and Mekada, E. (1995). The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor. J. Cell Biol. 128, 929-938.
17. Hong, J. P., Jung, H. D. and Kim, Y. W. (2006). Recombinant human epidermal growth factor (EGF) to enhance healing for diabetic foot ulcers. Ann. Plast. Surg. 56, 394-398; discussion 399-400.
18. Hubschmann, M. V., Skladchikova, G., Bock, E. and Berezin, V. (2005). Neural cell adhesion molecule function is regulated by metalloproteinase-mediated ectodomain release. J. Neurosci. Res. 80, 826-837.
19. Hundhausen, C., Misztela, D., Berkhout, T. A., Broadway, N., Saftig, P., Reiss, K., Hartmann, D., Fahrenholz, F., Postina, R., Matthews, V. et al. (2003). The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. Blood 102, 1186-1195.
20. Hynes, N. E., Horsch, K., Olayioye, M. A. and Badache, A. (2001). The ErbB receptor tyrosine family as signal integrators. Endocr. Relat. Cancer 8, 151-159.
21. Imanishi, J., Kamiyama, K., Iguchi, I., Kita, M., Sotozono, C. and Kinoshita, S. (2000). Growth factors: importance in wound healing and maintenance of transparency of the cornea. Prog. Retin. Eye Res. 19, 113-129.
22. Iwamoto, R. and Mekada, E. (2000). Heparin-binding EGF-like growth factor: a juxtacrine growth factor. Cytokine Growth Factor Rev. 11, 335-344.
23. Kaufmann, A., Musset, B., Limberg, S. H., Renigunta, V., Sus, R., Dalpke, A. H., Heeg, K. M., Robaye, B. and Hanley, P. J. (2005). "Host tissue damage" signal ATP promotes non-directional migration and negatively regulates toll-like receptor signaling in human monocytes. J. Biol. Chem. 280, 32459-32467.
24. Khakh, B. S. (2001). Molecular physiology of P2X receptors and ATP signalling at synapses. Nat. Rev. Neurosci. 2, 165-174.
25. Kimura, K., Nishimura, T. and Satoh, Y. (1999). Effects of ATP and its analogues on [Ca2+]i dynamics in the rabbit corneal epithelium. Arch. Histol. Cytol. 62, 129-138.
26. Klemke, R. L., Cai, S., Giannini, A. L., Gallagher, P. J., de Lanerolle, P. and Cheresh, D. A. (1997). Regulation of cell motility by mitogen-activated protein kinase. J. Cell Biol. 137, 481-492.
27. Klepeis, V. E., Cornell-Bell, A. and Trinkaus-Randall, V. (2001). Growth factors but not gap junctions play a role in injury-induced Ca2+ waves in epithelial cells. J. Cell Sci. 114, 4185-4195.
28. Klepeis, V. E., Weinger, I., Kaczmarek, E. and Trinkaus-Randall, V. (2004). P2Y receptors play a critical role in epithelial cell communication and migration. J. Cell. Biochem. 93, 1115-1133.
29. Lazarowski, E. R., Watt, W. C., Stutts, M. J., Boucher, R. C. and Harden, T. K. (1995). Pharmacological selectivity of the cloned human P2U-purinoceptor: potent activation by diadenosine tetraphosphate. Br. J. Pharmacol. 116, 1619-1627.
30. Martin, P. (1997). Wound healing-aiming for perfect skin regeneration. Science 276, 75-81.
31. Mazie, A. R., Spix, J. K., Block, E. R., Achebe, H. B. and Klarlund, J. K. (2006). Epithelial cell motility is triggered by activation of the EGF receptor through phosphatidic acid signaling. J. Cell Sci. 119, 1645-1654.
32. Mediero, A., Peral, A. and Pintor, J. (2006). Dual roles of diadenosine polyphosphates in corneal epithelial cell migration. Invest. Ophthalmol. Vis. Sci. 47, 4500-4506.
33. Mustoe, T. A., Cutler, N. R., Allman, R. M., Goode, P. S., Deuel, T. F., Prause, J. A., Bear, M, Serdar, C. M. and Pierce, G. F. (1994). A phase II study to evaluate recombinant platelet-derived growth factor-BB in the treatment of stage 3 and 4 pressure ulcers. Arch. Surg. 129, 213-219.
34. Paradiso, A. M., Ribeiro, C. M. and Boucher, R. C. (2001). Polarized signaling via purinoceptors in normal and cystic fibrosis airway epithelia. J. Gen. Physiol. 117, 53-67.
35. Pellegatti, P., Falzoni, S., Pinton, P., Rizzuto, R. and Di Virgilio, F. (2005). A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion. Mol. Biol. Cell 16, 3659-3665.
36. Raab, G. and Klagsbrun, M. (1997). Heparin-binding EGF-like growth factor. Biochim. Biophys. Acta 1333, F179-F199.
37. Raab, G., Higashiyama, S., Hetelekidis, S., Abraham, J. A., Damm, D., Ono, M. and Klagsbrun, M. (1994). Biosynthesis and processing by phorbol ester of the cells surface-associated precursor form of heparin-binding EGF-like growth factor. Biochem. Biophys. Res. Commun. 204, 592-597.
38. Robson, M. C., Phillips, L. G., Thomason, A., Altrock, B. W., Pence, P. C., Heggers, J. P., Johnston, A. E. McHugh, T. P., Anthony, M. S., Robson, L. E. et al. (1992). Recombinant human platelet-derived growth factor-BB for the treatment of chronic pressure ulcers. Ann. Plast. Surg. 29, 193-201.
39. Sahin, U., Weskamp, G., Kelly, K., Zhou, H. M., Higashiyama, S., Peschon, J., Hartmann, D., Saftig, F. and Blobel, C. P. (2004). Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands. J. Cell Biol. 164, 769-779.
40. Sanderson, M. P., Dempsey, P. J. and Dunbar, A. J. (2006). Control of ErbB signaling through metalloprotease mediated ectodomain shedding of EGF-like factors. Growth Factors 24, 121-136.
41. Schlondorff, J. and Blobel, C. P. (1999). Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding. J. Cell Sci. 112, 3603-3617.
42. Schwiebert, E. M. and Zsembery, A. (2003). Extracellular ATP as a signaling molecule for epithelial cells. Biochim. Biophys. Acta 1615, 7-32.
43. Smiell, J. M., Wieman, T. J., Steed, D. L., Perry, B. H., Sampson, A. R. and Schwab, B. H. (1999). Efficacy and safety, of becaplermin (recombinant human platelet-derived growth factor-BB) in patients with nonhealing, lower extremity diabetic ulcers: a combined analysis of four randomized studies. Wound Repair Regen. 7, 335-346.
44. Werner, S. and Grose, R. (2003). Regulation of wound healing by growth factors and cytokines. Physiol. Rev. 83, 835-870.
45. Xu, K. P., Ding, Y., Ling, J., Dong, Z. and Yu, F. S. (2004a). Wound-induced HB-EGF ectodomain shedding and EGFR activation in corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 45, 813-820.
46. Xu, K. P., Riggs, A., Ding, Y. and Yu, F. S. (2004b). Role of ErbB2 in corneal epithelial wound healing. Invest. Ophthalmol. Vis. Sci. 45, 4277-4283.
47. Yang, L., Cranson, D. and Trinkaus-Randall, V. (2004). Cellular injury induces activation of MAPK via P2Y receptors. J. Cell Biochem. 91, 938-950.
48. Zhang, Y. and Akhtar, R. A. (1996). Effect of epidermal growth factor on phosphatidylinositol 3-kinase activity in rabbit corneal epithelial cells. Exp. Eye Res. 63, 265-275.
49. Zhang, Y. and Akhtar, R. A. (1997). Epidermal growth factor stimulation of phosphatidylinositol 3-kinase during wound closure in rabbit corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 38, 1139-1148.