-
1
-
-
57349096045
-
The metabolic syndrome
-
Cornier M.A., Dabelea D., Hernandez T.L., et al. The metabolic syndrome. Endocr Rev 2008, 29(7):777-822.
-
(2008)
Endocr Rev
, vol.29
, Issue.7
, pp. 777-822
-
-
Cornier, M.A.1
Dabelea, D.2
Hernandez, T.L.3
-
2
-
-
13544253065
-
Metabolic syndrome: a clinical and molecular perspective
-
Moller D.E., Kaufman K.D. Metabolic syndrome: a clinical and molecular perspective. Annu Rev Med 2005, 56:45-62.
-
(2005)
Annu Rev Med
, vol.56
, pp. 45-62
-
-
Moller, D.E.1
Kaufman, K.D.2
-
3
-
-
34250019702
-
Explaining the decrease in U.S. deaths from coronary disease, 1980-2000
-
Ford E.S., Ajani U.A., Croft J.B., et al. Explaining the decrease in U.S. deaths from coronary disease, 1980-2000. N Engl J Med 2007, 356(23):2388-2398.
-
(2007)
N Engl J Med
, vol.356
, Issue.23
, pp. 2388-2398
-
-
Ford, E.S.1
Ajani, U.A.2
Croft, J.B.3
-
4
-
-
0031134779
-
The epidemiology of acute myocardial infarction and ischemic heart disease in Canada: data from 1976 to 1991
-
Brophy J.M. The epidemiology of acute myocardial infarction and ischemic heart disease in Canada: data from 1976 to 1991. Can J Cardiol 1997, 13(5):474-478.
-
(1997)
Can J Cardiol
, vol.13
, Issue.5
, pp. 474-478
-
-
Brophy, J.M.1
-
5
-
-
73749083481
-
Global estimates of the prevalence of diabetes for 2010 and 2030
-
Shaw J.E., Sicree R.A., Zimmet P.Z. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010, 87(1):4-14.
-
(2010)
Diabetes Res Clin Pract
, vol.87
, Issue.1
, pp. 4-14
-
-
Shaw, J.E.1
Sicree, R.A.2
Zimmet, P.Z.3
-
6
-
-
0027190372
-
The health risks of smoking. The Framingham Study: 34 years of follow-up
-
Freund K.M., Belanger A.J., D'Agostino R.B., et al. The health risks of smoking. The Framingham Study: 34 years of follow-up. Ann Epidemiol 1993, 3(4):417-424.
-
(1993)
Ann Epidemiol
, vol.3
, Issue.4
, pp. 417-424
-
-
Freund, K.M.1
Belanger, A.J.2
D'Agostino, R.B.3
-
7
-
-
0024311243
-
Blood pressure as a risk factor for cardiovascular disease. The Framingham Study-30 years of follow-up
-
Stokes J., Kannel W.B., Wolf P.A., et al. Blood pressure as a risk factor for cardiovascular disease. The Framingham Study-30 years of follow-up. Hypertension 1989, 13(Suppl 5):I13-I18.
-
(1989)
Hypertension
, vol.13
, Issue.SUPPL. 5
-
-
Stokes, J.1
Kannel, W.B.2
Wolf, P.A.3
-
8
-
-
0032515775
-
Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus: United Kingdom Prospective Diabetes Study (UKPDS: 23)
-
Turner R.C., Millns H., Neil H.A., et al. Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus: United Kingdom Prospective Diabetes Study (UKPDS: 23). BMJ 1998, 316(7134):823-828.
-
(1998)
BMJ
, vol.316
, Issue.7134
, pp. 823-828
-
-
Turner, R.C.1
Millns, H.2
Neil, H.A.3
-
9
-
-
0026597808
-
Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment
-
Manninen V., Tenkanen L., Koskinen P., et al. Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment. Circulation 1992, 85(1):37-45.
-
(1992)
Circulation
, vol.85
, Issue.1
, pp. 37-45
-
-
Manninen, V.1
Tenkanen, L.2
Koskinen, P.3
-
10
-
-
0025636233
-
Lipoproteins and coronary heart disease in the Helsinki Heart Study
-
Manttari M., Huttunen J.K., Koskinen P., et al. Lipoproteins and coronary heart disease in the Helsinki Heart Study. Eur Heart J 1990, 11(Suppl H):26-31.
-
(1990)
Eur Heart J
, vol.11
, Issue.SUPPL. H
, pp. 26-31
-
-
Manttari, M.1
Huttunen, J.K.2
Koskinen, P.3
-
11
-
-
0027942931
-
The triglyceride issue revisited. Findings from the Helsinki Heart Study
-
Tenkanen L., Pietila K., Manninen V., et al. The triglyceride issue revisited. Findings from the Helsinki Heart Study. Arch Intern Med 1994, 154(23):2714-2720.
-
(1994)
Arch Intern Med
, vol.154
, Issue.23
, pp. 2714-2720
-
-
Tenkanen, L.1
Pietila, K.2
Manninen, V.3
-
13
-
-
0036787345
-
Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process?
-
Gabriely I., Ma X.H., Yang X.M., et al. Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process?. Diabetes 2002, 51(10):2951-2958.
-
(2002)
Diabetes
, vol.51
, Issue.10
, pp. 2951-2958
-
-
Gabriely, I.1
Ma, X.H.2
Yang, X.M.3
-
14
-
-
42649084025
-
Cardiovascular disease and modifiable cardiometabolic risk factors
-
Cannon C.P. Cardiovascular disease and modifiable cardiometabolic risk factors. Clin Cornerstone 2007, 8(3):11-28.
-
(2007)
Clin Cornerstone
, vol.8
, Issue.3
, pp. 11-28
-
-
Cannon, C.P.1
-
15
-
-
0028836292
-
Weight, weight change, and coronary heart disease in women. Risk within the 'normal' weight range
-
Willett W.C., Manson J.E., Stampfer M.J., et al. Weight, weight change, and coronary heart disease in women. Risk within the 'normal' weight range. JAMA 1995, 273(6):461-465.
-
(1995)
JAMA
, vol.273
, Issue.6
, pp. 461-465
-
-
Willett, W.C.1
Manson, J.E.2
Stampfer, M.J.3
-
16
-
-
0014216480
-
Habitual level of physical activity and risk of coronary heart disease: the Framingham study
-
Kannel W.B. Habitual level of physical activity and risk of coronary heart disease: the Framingham study. Can Med Assoc J 1967, 96(12):811-812.
-
(1967)
Can Med Assoc J
, vol.96
, Issue.12
, pp. 811-812
-
-
Kannel, W.B.1
-
17
-
-
0034730069
-
Physical activity and coronary heart disease in men: The Harvard Alumni Health Study
-
Sesso H.D., Paffenbarger R.S., Lee I.M. Physical activity and coronary heart disease in men: The Harvard Alumni Health Study. Circulation 2000, 102(9):975-980.
-
(2000)
Circulation
, vol.102
, Issue.9
, pp. 975-980
-
-
Sesso, H.D.1
Paffenbarger, R.S.2
Lee, I.M.3
-
18
-
-
84855405617
-
Should waist circumference be replaced by index of central obesity (ICO) in definition of metabolic syndrome?
-
Parikh R., Mohan V., Joshi S. Should waist circumference be replaced by index of central obesity (ICO) in definition of metabolic syndrome?. Diabetes Metab Res Rev 2012, 28(1):3-5.
-
(2012)
Diabetes Metab Res Rev
, vol.28
, Issue.1
, pp. 3-5
-
-
Parikh, R.1
Mohan, V.2
Joshi, S.3
-
19
-
-
24344443725
-
Weight change and risk of developing type 2 diabetes
-
Oguma Y., Sesso H.D., Paffenbarger R.S., et al. Weight change and risk of developing type 2 diabetes. Obes Res 2005, 13(5):945-951.
-
(2005)
Obes Res
, vol.13
, Issue.5
, pp. 945-951
-
-
Oguma, Y.1
Sesso, H.D.2
Paffenbarger, R.S.3
-
20
-
-
0028917432
-
Weight gain as a risk factor for clinical diabetes mellitus in women
-
Colditz G.A., Willett W.C., Rotnitzky A., et al. Weight gain as a risk factor for clinical diabetes mellitus in women. Ann Intern Med 1995, 122(7):481-486.
-
(1995)
Ann Intern Med
, vol.122
, Issue.7
, pp. 481-486
-
-
Colditz, G.A.1
Willett, W.C.2
Rotnitzky, A.3
-
21
-
-
0036217052
-
Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
-
Lewis G.F., Carpentier A., Adeli K., et al. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev 2002, 23(2):201-229.
-
(2002)
Endocr Rev
, vol.23
, Issue.2
, pp. 201-229
-
-
Lewis, G.F.1
Carpentier, A.2
Adeli, K.3
-
22
-
-
44649148432
-
Impact of diabetes and hypertension on the heart
-
Pieske B., Wachter R. Impact of diabetes and hypertension on the heart. Curr Opin Cardiol 2008, 23(4):340-349.
-
(2008)
Curr Opin Cardiol
, vol.23
, Issue.4
, pp. 340-349
-
-
Pieske, B.1
Wachter, R.2
-
23
-
-
49849089716
-
Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options
-
Aneja A., Tang W.H., Bansilal S., et al. Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options. Am J Med 2008, 121(9):748-757.
-
(2008)
Am J Med
, vol.121
, Issue.9
, pp. 748-757
-
-
Aneja, A.1
Tang, W.H.2
Bansilal, S.3
-
24
-
-
33749321945
-
Role of changes in cardiac metabolism in development of diabetic cardiomyopathy
-
An D., Rodrigues B. Role of changes in cardiac metabolism in development of diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol 2006, 291(4):H1489-H1506.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
, Issue.4
-
-
An, D.1
Rodrigues, B.2
-
25
-
-
34247483998
-
Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study
-
Fox C.S., Coady S., Sorlie P.D., et al. Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study. Circulation 2007, 115(12):1544-1550.
-
(2007)
Circulation
, vol.115
, Issue.12
, pp. 1544-1550
-
-
Fox, C.S.1
Coady, S.2
Sorlie, P.D.3
-
26
-
-
0027978916
-
Regulation of fatty acid oxidation in the mammalian heart in health and disease
-
Lopaschuk G.D., Belke D.D., Gamble J., et al. Regulation of fatty acid oxidation in the mammalian heart in health and disease. Biochim Biophys Acta 1994, 1213(3):263-276.
-
(1994)
Biochim Biophys Acta
, vol.1213
, Issue.3
, pp. 263-276
-
-
Lopaschuk, G.D.1
Belke, D.D.2
Gamble, J.3
-
27
-
-
19444384446
-
Fatty acid metabolism is enhanced in type 2 diabetic hearts
-
Carley A.N., Severson D.L. Fatty acid metabolism is enhanced in type 2 diabetic hearts. Biochim Biophys Acta 2005, 1734(2):112-126.
-
(2005)
Biochim Biophys Acta
, vol.1734
, Issue.2
, pp. 112-126
-
-
Carley, A.N.1
Severson, D.L.2
-
29
-
-
78649658552
-
Chylomicron- and VLDL-derived lipids enter the heart through different pathways: in vivo evidence for receptor- and non-receptor-mediated fatty acid uptake
-
Bharadwaj K.G., Hiyama Y., Hu Y., et al. Chylomicron- and VLDL-derived lipids enter the heart through different pathways: in vivo evidence for receptor- and non-receptor-mediated fatty acid uptake. J Biol Chem 2010, 285(49):37976-37986.
-
(2010)
J Biol Chem
, vol.285
, Issue.49
, pp. 37976-37986
-
-
Bharadwaj, K.G.1
Hiyama, Y.2
Hu, Y.3
-
30
-
-
0030004652
-
Chylomicron assembly and catabolism: role of apolipoproteins and receptors
-
Hussain M.M., Kancha R.K., Zhou Z., et al. Chylomicron assembly and catabolism: role of apolipoproteins and receptors. Biochim Biophys Acta 1996, 1300(3):151-170.
-
(1996)
Biochim Biophys Acta
, vol.1300
, Issue.3
, pp. 151-170
-
-
Hussain, M.M.1
Kancha, R.K.2
Zhou, Z.3
-
31
-
-
79956313424
-
Postprandial lipoprotein metabolism: VLDL vs chylomicrons
-
Nakajima K., Nakano T., Tokita Y., et al. Postprandial lipoprotein metabolism: VLDL vs chylomicrons. Clin Chim Acta 2011, 412(15-16):1306-1318.
-
(2011)
Clin Chim Acta
, vol.412
, Issue.15-16
, pp. 1306-1318
-
-
Nakajima, K.1
Nakano, T.2
Tokita, Y.3
-
32
-
-
70449216881
-
Transport and metabolism of chylomicra
-
Havel R.J. Transport and metabolism of chylomicra. Am J Clin Nutr 1958, 6(6):662-668.
-
(1958)
Am J Clin Nutr
, vol.6
, Issue.6
, pp. 662-668
-
-
Havel, R.J.1
-
33
-
-
0014117576
-
Lipid composition of human serum lipoproteins
-
Skipski V.P., Barclay M., Barclay R.K., et al. Lipid composition of human serum lipoproteins. Biochem J 1967, 104(2):340-352.
-
(1967)
Biochem J
, vol.104
, Issue.2
, pp. 340-352
-
-
Skipski, V.P.1
Barclay, M.2
Barclay, R.K.3
-
34
-
-
0345098362
-
Selective partitioning of dietary fatty acids into the VLDL TG pool in the early postprandial period
-
Heath R.B., Karpe F., Milne R.W., et al. Selective partitioning of dietary fatty acids into the VLDL TG pool in the early postprandial period. J Lipid Res 2003, 44(11):2065-2072.
-
(2003)
J Lipid Res
, vol.44
, Issue.11
, pp. 2065-2072
-
-
Heath, R.B.1
Karpe, F.2
Milne, R.W.3
-
35
-
-
2942616538
-
Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression
-
Augustus A., Yagyu H., Haemmerle G., et al. Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression. J Biol Chem 2004, 279(24):25050-25057.
-
(2004)
J Biol Chem
, vol.279
, Issue.24
, pp. 25050-25057
-
-
Augustus, A.1
Yagyu, H.2
Haemmerle, G.3
-
36
-
-
19444382326
-
Perfusion of hearts with triglyceride-rich particles reproduces the metabolic abnormalities in lipotoxic cardiomyopathy
-
Pillutla P., Hwang Y.C., Augustus A., et al. Perfusion of hearts with triglyceride-rich particles reproduces the metabolic abnormalities in lipotoxic cardiomyopathy. Am J Physiol Endocrinol Metab 2005, 288(6):E1229-E1235.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
, Issue.6
-
-
Pillutla, P.1
Hwang, Y.C.2
Augustus, A.3
-
37
-
-
0036775676
-
Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism
-
Preiss-Landl K., Zimmermann R., Hammerle G., et al. Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism. Curr Opin Lipidol 2002, 13(5):471-481.
-
(2002)
Curr Opin Lipidol
, vol.13
, Issue.5
, pp. 471-481
-
-
Preiss-Landl, K.1
Zimmermann, R.2
Hammerle, G.3
-
38
-
-
77956628122
-
GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries
-
Davies B.S., Beigneux A.P., Barnes R.H., et al. GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries. Cell Metab 2010, 12(1):42-52.
-
(2010)
Cell Metab
, vol.12
, Issue.1
, pp. 42-52
-
-
Davies, B.S.1
Beigneux, A.P.2
Barnes, R.H.3
-
39
-
-
79957585342
-
Assessing the role of the glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) three-finger domain in binding lipoprotein lipase
-
Beigneux A.P., Davies B.S., Tat S., et al. Assessing the role of the glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) three-finger domain in binding lipoprotein lipase. J Biol Chem 2011, 286(22):19735-19743.
-
(2011)
J Biol Chem
, vol.286
, Issue.22
, pp. 19735-19743
-
-
Beigneux, A.P.1
Davies, B.S.2
Tat, S.3
-
40
-
-
77952575107
-
Chylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defects
-
Franssen R., Young S.G., Peelman F., et al. Chylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defects. Circ Cardiovasc Genet 2010, 3(2):169-178.
-
(2010)
Circ Cardiovasc Genet
, vol.3
, Issue.2
, pp. 169-178
-
-
Franssen, R.1
Young, S.G.2
Peelman, F.3
-
41
-
-
0037316670
-
Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy
-
Yagyu H., Chen G., Yokoyama M., et al. Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy. J Clin Invest 2003, 111(3):419-426.
-
(2003)
J Clin Invest
, vol.111
, Issue.3
, pp. 419-426
-
-
Yagyu, H.1
Chen, G.2
Yokoyama, M.3
-
42
-
-
0037155899
-
Very low density lipoprotein (VLDL) receptor-deficient mice have reduced lipoprotein lipase activity. Possible causes of hypertriglyceridemia and reduced body mass with VLDL receptor deficiency
-
Yagyu H., Lutz E.P., Kako Y., et al. Very low density lipoprotein (VLDL) receptor-deficient mice have reduced lipoprotein lipase activity. Possible causes of hypertriglyceridemia and reduced body mass with VLDL receptor deficiency. J Biol Chem 2002, 277(12):10037-10043.
-
(2002)
J Biol Chem
, vol.277
, Issue.12
, pp. 10037-10043
-
-
Yagyu, H.1
Lutz, E.P.2
Kako, Y.3
-
43
-
-
0035937846
-
Transcytosis of lipoprotein lipase across cultured endothelial cells requires both heparan sulfate proteoglycans and the very low density lipoprotein receptor
-
Obunike J.C., Lutz E.P., Li Z., et al. Transcytosis of lipoprotein lipase across cultured endothelial cells requires both heparan sulfate proteoglycans and the very low density lipoprotein receptor. J Biol Chem 2001, 276(12):8934-8941.
-
(2001)
J Biol Chem
, vol.276
, Issue.12
, pp. 8934-8941
-
-
Obunike, J.C.1
Lutz, E.P.2
Li, Z.3
-
44
-
-
3442880397
-
The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis
-
Goudriaan J.R., Espirito Santo S.M., Voshol P.J., et al. The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis. J Lipid Res 2004, 45(8):1475-1481.
-
(2004)
J Lipid Res
, vol.45
, Issue.8
, pp. 1475-1481
-
-
Goudriaan, J.R.1
Espirito Santo, S.M.2
Voshol, P.J.3
-
45
-
-
0036514622
-
Role of CD36 in membrane transport of long-chain fatty acids
-
Ibrahimi A., Abumrad N.A. Role of CD36 in membrane transport of long-chain fatty acids. Curr Opin Clin Nutr Metab Care 2002, 5(2):139-145.
-
(2002)
Curr Opin Clin Nutr Metab Care
, vol.5
, Issue.2
, pp. 139-145
-
-
Ibrahimi, A.1
Abumrad, N.A.2
-
46
-
-
0036846841
-
New insights into long-chain fatty acid uptake by heart muscle: a crucial role for fatty acid translocase/CD36
-
Brinkmann J.F., Abumrad N.A., Ibrahimi A., et al. New insights into long-chain fatty acid uptake by heart muscle: a crucial role for fatty acid translocase/CD36. Biochem J 2002, 367(Pt 3):561-570.
-
(2002)
Biochem J
, vol.367
, Issue.PART 3
, pp. 561-570
-
-
Brinkmann, J.F.1
Abumrad, N.A.2
Ibrahimi, A.3
-
47
-
-
0036693226
-
Cellular fatty acid uptake is acutely regulated by membrane-associated fatty acid-binding proteins
-
Luiken J.J., Bonen A., Glatz J.F. Cellular fatty acid uptake is acutely regulated by membrane-associated fatty acid-binding proteins. Prostaglandins Leukot Essent Fatty Acids 2002, 67(2-3):73-78.
-
(2002)
Prostaglandins Leukot Essent Fatty Acids
, vol.67
, Issue.2-3
, pp. 73-78
-
-
Luiken, J.J.1
Bonen, A.2
Glatz, J.F.3
-
48
-
-
0037806023
-
Characterization of a heart-specific fatty acid transport protein
-
Gimeno R.E., Ortegon A.M., Patel S., et al. Characterization of a heart-specific fatty acid transport protein. J Biol Chem 2003, 278(18):16039-16044.
-
(2003)
J Biol Chem
, vol.278
, Issue.18
, pp. 16039-16044
-
-
Gimeno, R.E.1
Ortegon, A.M.2
Patel, S.3
-
49
-
-
0034913962
-
Involvement of membrane-associated proteins in the acute regulation of cellular fatty acid uptake
-
[discussion: 151-7]
-
Glatz J.F., Luiken J.J., Bonen A. Involvement of membrane-associated proteins in the acute regulation of cellular fatty acid uptake. J Mol Neurosci 2001, 16(2-3):123-132. [discussion: 151-7].
-
(2001)
J Mol Neurosci
, vol.16
, Issue.2-3
, pp. 123-132
-
-
Glatz, J.F.1
Luiken, J.J.2
Bonen, A.3
-
50
-
-
0036787393
-
Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36
-
Luiken J.J., Koonen D.P., Willems J., et al. Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36. Diabetes 2002, 51(10):3113-3119.
-
(2002)
Diabetes
, vol.51
, Issue.10
, pp. 3113-3119
-
-
Luiken, J.J.1
Koonen, D.P.2
Willems, J.3
-
51
-
-
13444268937
-
Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy
-
Chiu H.C., Kovacs A., Blanton R.M., et al. Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy. Circ Res 2005, 96(2):225-233.
-
(2005)
Circ Res
, vol.96
, Issue.2
, pp. 225-233
-
-
Chiu, H.C.1
Kovacs, A.2
Blanton, R.M.3
-
52
-
-
33646862402
-
Cellular fatty acid uptake: the contribution of metabolism
-
Mashek D.G., Coleman R.A. Cellular fatty acid uptake: the contribution of metabolism. Curr Opin Lipidol 2006, 17(3):274-278.
-
(2006)
Curr Opin Lipidol
, vol.17
, Issue.3
, pp. 274-278
-
-
Mashek, D.G.1
Coleman, R.A.2
-
53
-
-
46749092545
-
Role of diet and fuel overabundance in the development and progression of heart failure
-
Chess D.J., Stanley W.C. Role of diet and fuel overabundance in the development and progression of heart failure. Cardiovasc Res 2008, 79(2):269-278.
-
(2008)
Cardiovasc Res
, vol.79
, Issue.2
, pp. 269-278
-
-
Chess, D.J.1
Stanley, W.C.2
-
54
-
-
0037138548
-
High levels of fatty acids delay the recovery of intracellular pH and cardiac efficiency in post-ischemic hearts by inhibiting glucose oxidation
-
Liu Q., Docherty J.C., Rendell J.C., et al. High levels of fatty acids delay the recovery of intracellular pH and cardiac efficiency in post-ischemic hearts by inhibiting glucose oxidation. J Am Coll Cardiol 2002, 39(4):718-725.
-
(2002)
J Am Coll Cardiol
, vol.39
, Issue.4
, pp. 718-725
-
-
Liu, Q.1
Docherty, J.C.2
Rendell, J.C.3
-
55
-
-
27844457564
-
Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity
-
Buchanan J., Mazumder P.K., Hu P., et al. Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity. Endocrinology 2005, 146(12):5341-5349.
-
(2005)
Endocrinology
, vol.146
, Issue.12
, pp. 5341-5349
-
-
Buchanan, J.1
Mazumder, P.K.2
Hu, P.3
-
56
-
-
34548848059
-
Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins
-
Boudina S., Sena S., Theobald H., et al. Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins. Diabetes 2007, 56(10):2457-2466.
-
(2007)
Diabetes
, vol.56
, Issue.10
, pp. 2457-2466
-
-
Boudina, S.1
Sena, S.2
Theobald, H.3
-
57
-
-
4644231528
-
Nuclear receptor signaling and cardiac energetics
-
Huss J.M., Kelly D.P. Nuclear receptor signaling and cardiac energetics. Circ Res 2004, 95(6):568-578.
-
(2004)
Circ Res
, vol.95
, Issue.6
, pp. 568-578
-
-
Huss, J.M.1
Kelly, D.P.2
-
58
-
-
0027055573
-
Neuroendocrine regulation and obesity
-
Brindley D.N. Neuroendocrine regulation and obesity. Int J Obes Relat Metab Disord 1992, 16(Suppl 3):S73-S79.
-
(1992)
Int J Obes Relat Metab Disord
, vol.16
, Issue.SUPPL. 3
-
-
Brindley, D.N.1
-
59
-
-
0031756839
-
Exaggerated stress-induced release of nonesterified fatty acids in JCR: LA-corpulent rats
-
McArthur M.D., Graham S.E., Russell J.C., et al. Exaggerated stress-induced release of nonesterified fatty acids in JCR: LA-corpulent rats. Metabolism 1998, 47(11):1383-1390.
-
(1998)
Metabolism
, vol.47
, Issue.11
, pp. 1383-1390
-
-
McArthur, M.D.1
Graham, S.E.2
Russell, J.C.3
-
60
-
-
0033860359
-
Insulin resistance and cardiovascular disease
-
Ginsberg H.N. Insulin resistance and cardiovascular disease. J Clin Invest 2000, 106(4):453-458.
-
(2000)
J Clin Invest
, vol.106
, Issue.4
, pp. 453-458
-
-
Ginsberg, H.N.1
-
61
-
-
1442352339
-
Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach
-
Bays H., Mandarino L., DeFronzo R.A. Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach. J Clin Endocrinol Metab 2004, 89(2):463-478.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.2
, pp. 463-478
-
-
Bays, H.1
Mandarino, L.2
DeFronzo, R.A.3
-
62
-
-
38949161289
-
Alterations in plasma and tissue lipids associated with obesity and metabolic syndrome
-
Aguilera C.M., Gil-Campos M., Canete R., et al. Alterations in plasma and tissue lipids associated with obesity and metabolic syndrome. Clin Sci (Lond) 2008, 114(3):183-193.
-
(2008)
Clin Sci (Lond)
, vol.114
, Issue.3
, pp. 183-193
-
-
Aguilera, C.M.1
Gil-Campos, M.2
Canete, R.3
-
63
-
-
0031014830
-
Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
-
Boden G. Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 1997, 46(1):3-10.
-
(1997)
Diabetes
, vol.46
, Issue.1
, pp. 3-10
-
-
Boden, G.1
-
64
-
-
0025173007
-
Stimulation of apolipoprotein secretion in very-low-density and high-density lipoproteins from cultured rat hepatocytes by dexamethasone
-
Martin-Sanz P., Vance J.E., Brindley D.N. Stimulation of apolipoprotein secretion in very-low-density and high-density lipoproteins from cultured rat hepatocytes by dexamethasone. Biochem J 1990, 271(3):575-583.
-
(1990)
Biochem J
, vol.271
, Issue.3
, pp. 575-583
-
-
Martin-Sanz, P.1
Vance, J.E.2
Brindley, D.N.3
-
65
-
-
0029121196
-
Effects of dexamethasone on the synthesis, degradation, and secretion of apolipoprotein B in cultured rat hepatocytes
-
Wang C.N., McLeod R.S., Yao Z., et al. Effects of dexamethasone on the synthesis, degradation, and secretion of apolipoprotein B in cultured rat hepatocytes. Arterioscler Thromb Vasc Biol 1995, 15(9):1481-1491.
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, Issue.9
, pp. 1481-1491
-
-
Wang, C.N.1
McLeod, R.S.2
Yao, Z.3
-
66
-
-
34248370974
-
Lipids in the heart: a source of fuel and a source of toxins
-
Park T.S., Yamashita H., Blaner W.S., et al. Lipids in the heart: a source of fuel and a source of toxins. Curr Opin Lipidol 2007, 18(3):277-282.
-
(2007)
Curr Opin Lipidol
, vol.18
, Issue.3
, pp. 277-282
-
-
Park, T.S.1
Yamashita, H.2
Blaner, W.S.3
-
67
-
-
30744444209
-
Cardiac lipoprotein lipase: metabolic basis for diabetic heart disease
-
Pulinilkunnil T., Rodrigues B. Cardiac lipoprotein lipase: metabolic basis for diabetic heart disease. Cardiovasc Res 2006, 69(2):329-340.
-
(2006)
Cardiovasc Res
, vol.69
, Issue.2
, pp. 329-340
-
-
Pulinilkunnil, T.1
Rodrigues, B.2
-
68
-
-
34547699873
-
Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification
-
Ouwens D.M., Diamant M., Fodor M., et al. Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification. Diabetologia 2007, 50(9):1938-1948.
-
(2007)
Diabetologia
, vol.50
, Issue.9
, pp. 1938-1948
-
-
Ouwens, D.M.1
Diamant, M.2
Fodor, M.3
-
69
-
-
3042739406
-
Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese Zucker rats
-
Coort S.L., Hasselbaink D.M., Koonen D.P., et al. Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese Zucker rats. Diabetes 2004, 53(7):1655-1663.
-
(2004)
Diabetes
, vol.53
, Issue.7
, pp. 1655-1663
-
-
Coort, S.L.1
Hasselbaink, D.M.2
Koonen, D.P.3
-
70
-
-
1442357796
-
Increased FAT (fatty acid translocase)/CD36-mediated long-chain fatty acid uptake in cardiac myocytes from obese Zucker rats
-
Coort S.L., Luiken J.J., van der Vusse G.J., et al. Increased FAT (fatty acid translocase)/CD36-mediated long-chain fatty acid uptake in cardiac myocytes from obese Zucker rats. Biochem Soc Trans 2004, 32(Pt 1):83-85.
-
(2004)
Biochem Soc Trans
, vol.32
, Issue.PART 1
, pp. 83-85
-
-
Coort, S.L.1
Luiken, J.J.2
van der Vusse, G.J.3
-
71
-
-
35848965708
-
CD36 expression contributes to age-induced cardiomyopathy in mice
-
Koonen D.P., Febbraio M., Bonnet S., et al. CD36 expression contributes to age-induced cardiomyopathy in mice. Circulation 2007, 116(19):2139-2147.
-
(2007)
Circulation
, vol.116
, Issue.19
, pp. 2139-2147
-
-
Koonen, D.P.1
Febbraio, M.2
Bonnet, S.3
-
72
-
-
79960938919
-
Subcellular trafficking of the substrate transporters GLUT4 and CD36 in cardiomyocytes
-
Steinbusch L.K., Schwenk R.W., Ouwens D.M., et al. Subcellular trafficking of the substrate transporters GLUT4 and CD36 in cardiomyocytes. Cell Mol Life Sci 2011, 68(15):2525-2538.
-
(2011)
Cell Mol Life Sci
, vol.68
, Issue.15
, pp. 2525-2538
-
-
Steinbusch, L.K.1
Schwenk, R.W.2
Ouwens, D.M.3
-
74
-
-
74949133862
-
Myocardial fatty acid metabolism in health and disease
-
Lopaschuk G.D., Ussher J.R., Folmes C.D., et al. Myocardial fatty acid metabolism in health and disease. Physiol Rev 2010, 90(1):207-258.
-
(2010)
Physiol Rev
, vol.90
, Issue.1
, pp. 207-258
-
-
Lopaschuk, G.D.1
Ussher, J.R.2
Folmes, C.D.3
-
75
-
-
76049092146
-
Acyl-CoA synthesis, lipid metabolism and lipotoxicity
-
Li L.O., Klett E.L., Coleman R.A. Acyl-CoA synthesis, lipid metabolism and lipotoxicity. Biochim Biophys Acta 2010, 1801(3):246-251.
-
(2010)
Biochim Biophys Acta
, vol.1801
, Issue.3
, pp. 246-251
-
-
Li, L.O.1
Klett, E.L.2
Coleman, R.A.3
-
76
-
-
33846089386
-
Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart
-
de Jong H., Neal A.C., Coleman R.A., et al. Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart. Biochim Biophys Acta 2007, 1771(1):75-82.
-
(2007)
Biochim Biophys Acta
, vol.1771
, Issue.1
, pp. 75-82
-
-
de Jong, H.1
Neal, A.C.2
Coleman, R.A.3
-
77
-
-
0031043030
-
The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis
-
McGarry J.D., Brown N.F. The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis. Eur J Biochem 1997, 244(1):1-14.
-
(1997)
Eur J Biochem
, vol.244
, Issue.1
, pp. 1-14
-
-
McGarry, J.D.1
Brown, N.F.2
-
78
-
-
0021716358
-
Malonyl CoA inhibition of carnitine palmitoyltransferase in rat heart mitochondria
-
Paulson D.J., Ward K.M., Shug A.L. Malonyl CoA inhibition of carnitine palmitoyltransferase in rat heart mitochondria. FEBS Lett 1984, 176(2):381-384.
-
(1984)
FEBS Lett
, vol.176
, Issue.2
, pp. 381-384
-
-
Paulson, D.J.1
Ward, K.M.2
Shug, A.L.3
-
79
-
-
0017875758
-
Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA
-
McGarry J.D., Leatherman G.F., Foster D.W. Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA. J Biol Chem 1978, 253(12):4128-4136.
-
(1978)
J Biol Chem
, vol.253
, Issue.12
, pp. 4128-4136
-
-
McGarry, J.D.1
Leatherman, G.F.2
Foster, D.W.3
-
80
-
-
0027453493
-
Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart
-
Saddik M., Gamble J., Witters L.A., et al. Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart. J Biol Chem 1993, 268(34):25836-25845.
-
(1993)
J Biol Chem
, vol.268
, Issue.34
, pp. 25836-25845
-
-
Saddik, M.1
Gamble, J.2
Witters, L.A.3
-
81
-
-
0028886244
-
L-carnitine improvement of cardiac function is associated with a stimulation in glucose but not fatty acid metabolism in carnitine-deficient hearts
-
Broderick T.L., Panagakis G., DiDomenico D., et al. L-carnitine improvement of cardiac function is associated with a stimulation in glucose but not fatty acid metabolism in carnitine-deficient hearts. Cardiovasc Res 1995, 30(5):815-820.
-
(1995)
Cardiovasc Res
, vol.30
, Issue.5
, pp. 815-820
-
-
Broderick, T.L.1
Panagakis, G.2
DiDomenico, D.3
-
82
-
-
0027486343
-
Malonyl-CoA metabolism in cardiac myocytes and its relevance to the control of fatty acid oxidation
-
Awan M.M., Saggerson E.D. Malonyl-CoA metabolism in cardiac myocytes and its relevance to the control of fatty acid oxidation. Biochem J 1993, 295(Pt 1):61-66.
-
(1993)
Biochem J
, vol.295
, Issue.PART 1
, pp. 61-66
-
-
Awan, M.M.1
Saggerson, E.D.2
-
83
-
-
31344467300
-
Malonyl-CoA decarboxylase is a major regulator of myocardial fatty acid oxidation
-
Cuthbert K.D., Dyck J.R. Malonyl-CoA decarboxylase is a major regulator of myocardial fatty acid oxidation. Curr Hypertens Rep 2005, 7(6):407-411.
-
(2005)
Curr Hypertens Rep
, vol.7
, Issue.6
, pp. 407-411
-
-
Cuthbert, K.D.1
Dyck, J.R.2
-
84
-
-
35448999775
-
Chapter 5. Oxidation of fatty acids in eukaryotes
-
Elsevier
-
Schulz H. Chapter 5. Oxidation of fatty acids in eukaryotes. New comprehensive biochemistry 2002, vol. 36:127-150. Elsevier.
-
(2002)
New comprehensive biochemistry
, vol.36
, pp. 127-150
-
-
Schulz, H.1
-
85
-
-
33644660537
-
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
-
Finck B.N., Kelly D.P. PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J Clin Invest 2006, 116(3):615-622.
-
(2006)
J Clin Invest
, vol.116
, Issue.3
, pp. 615-622
-
-
Finck, B.N.1
Kelly, D.P.2
-
86
-
-
44649151707
-
The PPAR trio: regulators of myocardial energy metabolism in health and disease
-
Madrazo J.A., Kelly D.P. The PPAR trio: regulators of myocardial energy metabolism in health and disease. J Mol Cell Cardiol 2008, 44(6):968-975.
-
(2008)
J Mol Cell Cardiol
, vol.44
, Issue.6
, pp. 968-975
-
-
Madrazo, J.A.1
Kelly, D.P.2
-
87
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin J., Handschin C., Spiegelman B.M. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab 2005, 1(6):361-370.
-
(2005)
Cell Metab
, vol.1
, Issue.6
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
88
-
-
0034467428
-
PPAR signaling in the control of cardiac energy metabolism
-
Barger P.M., Kelly D.P. PPAR signaling in the control of cardiac energy metabolism. Trends Cardiovasc Med 2000, 10(6):238-245.
-
(2000)
Trends Cardiovasc Med
, vol.10
, Issue.6
, pp. 238-245
-
-
Barger, P.M.1
Kelly, D.P.2
-
89
-
-
34447321069
-
Roles of PPARs on regulating myocardial energy and lipid homeostasis
-
Yang Q., Li Y. Roles of PPARs on regulating myocardial energy and lipid homeostasis. J Mol Med (Berl) 2007, 85(7):697-706.
-
(2007)
J Mol Med (Berl)
, vol.85
, Issue.7
, pp. 697-706
-
-
Yang, Q.1
Li, Y.2
-
90
-
-
33747853190
-
Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway
-
Finck B.N., Gropler M.C., Chen Z., et al. Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway. Cell Metab 2006, 4(3):199-210.
-
(2006)
Cell Metab
, vol.4
, Issue.3
, pp. 199-210
-
-
Finck, B.N.1
Gropler, M.C.2
Chen, Z.3
-
91
-
-
0034698051
-
Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity
-
Watanabe K., Fujii H., Takahashi T., et al. Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity. J Biol Chem 2000, 275(29):22293-22299.
-
(2000)
J Biol Chem
, vol.275
, Issue.29
, pp. 22293-22299
-
-
Watanabe, K.1
Fujii, H.2
Takahashi, T.3
-
92
-
-
0037040203
-
A role for peroxisome proliferator-activated receptor alpha (PPARalpha) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated with higher concentrations of malonyl-CoA and reduced expression of malonyl-CoA decarboxylase
-
Campbell F.M., Kozak R., Wagner A., et al. A role for peroxisome proliferator-activated receptor alpha (PPARalpha) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated with higher concentrations of malonyl-CoA and reduced expression of malonyl-CoA decarboxylase. J Biol Chem 2002, 277(6):4098-4103.
-
(2002)
J Biol Chem
, vol.277
, Issue.6
, pp. 4098-4103
-
-
Campbell, F.M.1
Kozak, R.2
Wagner, A.3
-
93
-
-
0033594980
-
A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders
-
Leone T.C., Weinheimer C.J., Kelly D.P. A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci U S A 1999, 96(13):7473-7478.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.13
, pp. 7473-7478
-
-
Leone, T.C.1
Weinheimer, C.J.2
Kelly, D.P.3
-
94
-
-
21144446106
-
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis
-
Leone T.C., Lehman J.J., Finck B.N., et al. PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol 2005, 3(4):e101.
-
(2005)
PLoS Biol
, vol.3
, Issue.4
-
-
Leone, T.C.1
Lehman, J.J.2
Finck, B.N.3
-
95
-
-
49849085702
-
The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis
-
Lehman J.J., Boudina S., Banke N.H., et al. The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis. Am J Physiol Heart Circ Physiol 2008, 295(1):H185-H196.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
, Issue.1
-
-
Lehman, J.J.1
Boudina, S.2
Banke, N.H.3
-
96
-
-
22144434964
-
Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle
-
Arany Z., He H., Lin J., et al. Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle. Cell Metab 2005, 1(4):259-271.
-
(2005)
Cell Metab
, vol.1
, Issue.4
, pp. 259-271
-
-
Arany, Z.1
He, H.2
Lin, J.3
-
97
-
-
31644445201
-
Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus
-
Herrero P., Peterson L.R., McGill J.B., et al. Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus. J Am Coll Cardiol 2006, 47(3):598-604.
-
(2006)
J Am Coll Cardiol
, vol.47
, Issue.3
, pp. 598-604
-
-
Herrero, P.1
Peterson, L.R.2
McGill, J.B.3
-
98
-
-
27444441492
-
Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity
-
Boudina S., Sena S., O'Neill B.T., et al. Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity. Circulation 2005, 112(17):2686-2695.
-
(2005)
Circulation
, vol.112
, Issue.17
, pp. 2686-2695
-
-
Boudina, S.1
Sena, S.2
O'Neill, B.T.3
-
99
-
-
63649106676
-
Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart
-
Boudina S., Bugger H., Sena S., et al. Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart. Circulation 2009, 119(9):1272-1283.
-
(2009)
Circulation
, vol.119
, Issue.9
, pp. 1272-1283
-
-
Boudina, S.1
Bugger, H.2
Sena, S.3
-
100
-
-
33644766038
-
Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy
-
Shen X., Zheng S., Metreveli N.S., et al. Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy. Diabetes 2006, 55(3):798-805.
-
(2006)
Diabetes
, vol.55
, Issue.3
, pp. 798-805
-
-
Shen, X.1
Zheng, S.2
Metreveli, N.S.3
-
101
-
-
18244379331
-
Superoxide activates mitochondrial uncoupling proteins
-
Echtay K.S., Roussel D., St-Pierre J., et al. Superoxide activates mitochondrial uncoupling proteins. Nature 2002, 415(6867):96-99.
-
(2002)
Nature
, vol.415
, Issue.6867
, pp. 96-99
-
-
Echtay, K.S.1
Roussel, D.2
St-Pierre, J.3
-
102
-
-
0037339706
-
Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production
-
Ye G., Metreveli N.S., Ren J., et al. Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production. Diabetes 2003, 52(3):777-783.
-
(2003)
Diabetes
, vol.52
, Issue.3
, pp. 777-783
-
-
Ye, G.1
Metreveli, N.S.2
Ren, J.3
-
103
-
-
0141499890
-
Beneficial effects of trimetazidine in ex vivo working ischemic hearts are due to a stimulation of glucose oxidation secondary to inhibition of long-chain 3-ketoacyl coenzyme a thiolase
-
Lopaschuk G.D., Barr R., Thomas P.D., et al. Beneficial effects of trimetazidine in ex vivo working ischemic hearts are due to a stimulation of glucose oxidation secondary to inhibition of long-chain 3-ketoacyl coenzyme a thiolase. Circ Res 2003, 93(3):e33-e37.
-
(2003)
Circ Res
, vol.93
, Issue.3
-
-
Lopaschuk, G.D.1
Barr, R.2
Thomas, P.D.3
-
104
-
-
77957153116
-
Metabolic adaptation follows contractile dysfunction in the heart of obese Zucker rats fed a high-fat "Western" diet
-
Burgmaier M., Sen S., Philip F., et al. Metabolic adaptation follows contractile dysfunction in the heart of obese Zucker rats fed a high-fat "Western" diet. Obesity (Silver Spring) 2010, 18(10):1895-1901.
-
(2010)
Obesity (Silver Spring)
, vol.18
, Issue.10
, pp. 1895-1901
-
-
Burgmaier, M.1
Sen, S.2
Philip, F.3
-
105
-
-
0036143320
-
The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus
-
Finck B.N., Lehman J.J., Leone T.C., et al. The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. J Clin Invest 2002, 109(1):121-130.
-
(2002)
J Clin Invest
, vol.109
, Issue.1
, pp. 121-130
-
-
Finck, B.N.1
Lehman, J.J.2
Leone, T.C.3
-
106
-
-
0038000660
-
Control of cardiac pyruvate dehydrogenase activity in peroxisome proliferator-activated receptor-alpha transgenic mice
-
Hopkins T.A., Sugden M.C., Holness M.J., et al. Control of cardiac pyruvate dehydrogenase activity in peroxisome proliferator-activated receptor-alpha transgenic mice. Am J Physiol Heart Circ Physiol 2003, 285(1):H270-H276.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
, Issue.1
-
-
Hopkins, T.A.1
Sugden, M.C.2
Holness, M.J.3
-
107
-
-
0033803048
-
Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis
-
Lehman J.J., Barger P.M., Kovacs A., et al. Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest 2000, 106(7):847-856.
-
(2000)
J Clin Invest
, vol.106
, Issue.7
, pp. 847-856
-
-
Lehman, J.J.1
Barger, P.M.2
Kovacs, A.3
-
108
-
-
33750211736
-
Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury
-
Dyck J.R., Hopkins T.A., Bonnet S., et al. Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury. Circulation 2006, 114(16):1721-1728.
-
(2006)
Circulation
, vol.114
, Issue.16
, pp. 1721-1728
-
-
Dyck, J.R.1
Hopkins, T.A.2
Bonnet, S.3
-
109
-
-
4444226906
-
Malonyl coenzyme A decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation
-
Dyck J.R., Cheng J.F., Stanley W.C., et al. Malonyl coenzyme A decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation. Circ Res 2004, 94(9):e78-e84.
-
(2004)
Circ Res
, vol.94
, Issue.9
-
-
Dyck, J.R.1
Cheng, J.F.2
Stanley, W.C.3
-
110
-
-
0024262853
-
Etomoxir, a carnitine palmitoyltransferase I inhibitor, protects hearts from fatty acid-induced ischemic injury independent of changes in long chain acylcarnitine
-
Lopaschuk G.D., Wall S.R., Olley P.M., et al. Etomoxir, a carnitine palmitoyltransferase I inhibitor, protects hearts from fatty acid-induced ischemic injury independent of changes in long chain acylcarnitine. Circ Res 1988, 63(6):1036-1043.
-
(1988)
Circ Res
, vol.63
, Issue.6
, pp. 1036-1043
-
-
Lopaschuk, G.D.1
Wall, S.R.2
Olley, P.M.3
-
111
-
-
0038433338
-
Partial inhibition of fatty acid oxidation increases regional contractile power and efficiency during demand-induced ischemia
-
Chandler M.P., Chavez P.N., McElfresh T.A., et al. Partial inhibition of fatty acid oxidation increases regional contractile power and efficiency during demand-induced ischemia. Cardiovasc Res 2003, 59(1):143-151.
-
(2003)
Cardiovasc Res
, vol.59
, Issue.1
, pp. 143-151
-
-
Chandler, M.P.1
Chavez, P.N.2
McElfresh, T.A.3
-
112
-
-
34247626856
-
CD36 deficiency rescues lipotoxic cardiomyopathy
-
Yang J., Sambandam N., Han X., et al. CD36 deficiency rescues lipotoxic cardiomyopathy. Circ Res 2007, 100(8):1208-1217.
-
(2007)
Circ Res
, vol.100
, Issue.8
, pp. 1208-1217
-
-
Yang, J.1
Sambandam, N.2
Han, X.3
-
113
-
-
0026721574
-
Rationale and application of fatty acid oxidation inhibitors in treatment of diabetes mellitus
-
Foley J.E. Rationale and application of fatty acid oxidation inhibitors in treatment of diabetes mellitus. Diabetes Care 1992, 15(6):773-784.
-
(1992)
Diabetes Care
, vol.15
, Issue.6
, pp. 773-784
-
-
Foley, J.E.1
-
114
-
-
42549169797
-
Metabolic (in)flexibility of the diabetic heart
-
Larsen T.S., Aasum E. Metabolic (in)flexibility of the diabetic heart. Cardiovasc Drugs Ther 2008, 22(2):91-95.
-
(2008)
Cardiovasc Drugs Ther
, vol.22
, Issue.2
, pp. 91-95
-
-
Larsen, T.S.1
Aasum, E.2
-
115
-
-
34447637299
-
The biological synthesis of phospholipids
-
Kennedy E.P. The biological synthesis of phospholipids. Can J Biochem Physiol 1956, 34(2):334-348.
-
(1956)
Can J Biochem Physiol
, vol.34
, Issue.2
, pp. 334-348
-
-
Kennedy, E.P.1
-
117
-
-
77950788493
-
Shedding light on the enigma of myocardial lipotoxicity: the involvement of known and putative regulators of fatty acid storage and mobilization
-
Brindley D.N., Kok B.P., Kienesberger P.C., et al. Shedding light on the enigma of myocardial lipotoxicity: the involvement of known and putative regulators of fatty acid storage and mobilization. Am J Physiol Endocrinol Metab 2010, 298(5):E897-E908.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
, Issue.5
-
-
Brindley, D.N.1
Kok, B.P.2
Kienesberger, P.C.3
-
118
-
-
0345171460
-
Enzymes of triacylglycerol synthesis and their regulation
-
Coleman R.A., Lee D.P. Enzymes of triacylglycerol synthesis and their regulation. Prog Lipid Res 2004, 43(2):134-176.
-
(2004)
Prog Lipid Res
, vol.43
, Issue.2
, pp. 134-176
-
-
Coleman, R.A.1
Lee, D.P.2
-
119
-
-
0037081758
-
Redox regulation of cytosolic glycerol-3-phosphate dehydrogenase: Cys(102) is the target of the redox control and essential for the catalytic activity
-
Kim J.Y., Park H.S., Kang S.I., et al. Redox regulation of cytosolic glycerol-3-phosphate dehydrogenase: Cys(102) is the target of the redox control and essential for the catalytic activity. Biochim Biophys Acta 2002, 1569(1-3):67-74.
-
(2002)
Biochim Biophys Acta
, vol.1569
, Issue.1-3
, pp. 67-74
-
-
Kim, J.Y.1
Park, H.S.2
Kang, S.I.3
-
120
-
-
0014108686
-
Glycerol kinase activities in rat heart and adipose tissue
-
Robinson J., Newsholme E.A. Glycerol kinase activities in rat heart and adipose tissue. Biochem J 1967, 104(1):2C-4C.
-
(1967)
Biochem J
, vol.104
, Issue.1
-
-
Robinson, J.1
Newsholme, E.A.2
-
121
-
-
18244366065
-
Tissue-dependent alterations in lipid mass in mice lacking glycerol kinase
-
Golovko M.Y., Hovda J.T., Cai Z.J., et al. Tissue-dependent alterations in lipid mass in mice lacking glycerol kinase. Lipids 2005, 40(3):287-293.
-
(2005)
Lipids
, vol.40
, Issue.3
, pp. 287-293
-
-
Golovko, M.Y.1
Hovda, J.T.2
Cai, Z.J.3
-
122
-
-
66849089697
-
Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis
-
Takeuchi K., Reue K. Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis. Am J Physiol Endocrinol Metab 2009, 296(6):E1195-E1209.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
, Issue.6
-
-
Takeuchi, K.1
Reue, K.2
-
123
-
-
67349112100
-
Glycerol-3-phosphate acyltransferases: rate limiting enzymes of triacylglycerol biosynthesis
-
Wendel A.A., Lewin T.M., Coleman R.A. Glycerol-3-phosphate acyltransferases: rate limiting enzymes of triacylglycerol biosynthesis. Biochim Biophys Acta 2009, 1791(6):501-506.
-
(2009)
Biochim Biophys Acta
, vol.1791
, Issue.6
, pp. 501-506
-
-
Wendel, A.A.1
Lewin, T.M.2
Coleman, R.A.3
-
124
-
-
50949096938
-
Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition
-
Lewin T.M., de Jong H., Schwerbrock N.J., et al. Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition. Biochim Biophys Acta 2008, 1781(6-7):352-358.
-
(2008)
Biochim Biophys Acta
, vol.1781
, Issue.6-7
, pp. 352-358
-
-
Lewin, T.M.1
de Jong, H.2
Schwerbrock, N.J.3
-
125
-
-
12844249385
-
Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARalpha in murine heart
-
Lu B., Jiang Y.J., Zhou Y., et al. Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARalpha in murine heart. Biochem J 2005, 385(Pt 2):469-477.
-
(2005)
Biochem J
, vol.385
, Issue.PART 2
, pp. 469-477
-
-
Lu, B.1
Jiang, Y.J.2
Zhou, Y.3
-
126
-
-
59649088176
-
Thematic Review Series: glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism
-
Reue K., Brindley D.N. Thematic Review Series: glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism. J Lipid Res 2008, 49(12):2493-2503.
-
(2008)
J Lipid Res
, vol.49
, Issue.12
, pp. 2493-2503
-
-
Reue, K.1
Brindley, D.N.2
-
127
-
-
33947542353
-
Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns
-
Donkor J., Sariahmetoglu M., Dewald J., et al. Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns. J Biol Chem 2007, 282(6):3450-3457.
-
(2007)
J Biol Chem
, vol.282
, Issue.6
, pp. 3450-3457
-
-
Donkor, J.1
Sariahmetoglu, M.2
Dewald, J.3
-
128
-
-
33646920976
-
2+-dependent phosphatidate phosphatase enzyme
-
2+-dependent phosphatidate phosphatase enzyme. J Biol Chem 2006, 281(14):9210-9218.
-
(2006)
J Biol Chem
, vol.281
, Issue.14
, pp. 9210-9218
-
-
Han, G.S.1
Wu, W.I.2
Carman, G.M.3
-
129
-
-
78649756850
-
Lipin proteins form homo- and hetero-oligomers
-
Liu G.H., Qu J., Carmack A.E., et al. Lipin proteins form homo- and hetero-oligomers. Biochem J 2010, 432(1):65-76.
-
(2010)
Biochem J
, vol.432
, Issue.1
, pp. 65-76
-
-
Liu, G.H.1
Qu, J.2
Carmack, A.E.3
-
130
-
-
77951979740
-
Characterization of the human LPIN1-encoded phosphatidate phosphatase isoforms
-
Han G.S., Carman G.M. Characterization of the human LPIN1-encoded phosphatidate phosphatase isoforms. J Biol Chem 2010, 285(19):14628-14638.
-
(2010)
J Biol Chem
, vol.285
, Issue.19
, pp. 14628-14638
-
-
Han, G.S.1
Carman, G.M.2
-
131
-
-
70350399460
-
A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2
-
Donkor J., Zhang P., Wong S., et al. A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2. J Biol Chem 2009, 284(43):29968-29978.
-
(2009)
J Biol Chem
, vol.284
, Issue.43
, pp. 29968-29978
-
-
Donkor, J.1
Zhang, P.2
Wong, S.3
-
132
-
-
33846975789
-
Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1
-
Harris T.E., Huffman T.A., Chi A., et al. Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1. J Biol Chem 2007, 282(1):277-286.
-
(2007)
J Biol Chem
, vol.282
, Issue.1
, pp. 277-286
-
-
Harris, T.E.1
Huffman, T.A.2
Chi, A.3
-
133
-
-
79961165137
-
MTOR complex 1 regulates lipin 1 localization to control the SREBP pathway
-
Peterson T.R., Sengupta S.S., Harris T.E., et al. mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway. Cell 2011, 146(3):408-420.
-
(2011)
Cell
, vol.146
, Issue.3
, pp. 408-420
-
-
Peterson, T.R.1
Sengupta, S.S.2
Harris, T.E.3
-
134
-
-
77956703908
-
A phosphatidic acid binding/nuclear localization motif determines lipin-1 function in lipid metabolism and adipogenesis
-
Ren H., Federico L., Huang H., et al. A phosphatidic acid binding/nuclear localization motif determines lipin-1 function in lipid metabolism and adipogenesis. Mol Biol Cell 2010, 21(18):3171-3181.
-
(2010)
Mol Biol Cell
, vol.21
, Issue.18
, pp. 3171-3181
-
-
Ren, H.1
Federico, L.2
Huang, H.3
-
135
-
-
0022400107
-
Regulation of the translocation of phosphatidate phosphohydrolase between the cytosol and the endoplasmic reticulum of rat liver. Effects of unsaturated fatty acids, spermine, nucleotides, albumin and chlorpromazine
-
Hopewell R., Martin-Sanz P., Martin A., et al. Regulation of the translocation of phosphatidate phosphohydrolase between the cytosol and the endoplasmic reticulum of rat liver. Effects of unsaturated fatty acids, spermine, nucleotides, albumin and chlorpromazine. Biochem J 1985, 232(2):485-491.
-
(1985)
Biochem J
, vol.232
, Issue.2
, pp. 485-491
-
-
Hopewell, R.1
Martin-Sanz, P.2
Martin, A.3
-
136
-
-
0021149455
-
Long-chain fatty acids and their acyl-CoA esters cause the translocation of phosphatidate phosphohydrolase from the cytosolic to the microsomal fraction of rat liver
-
Martin-Sanz P., Hopewell R., Brindley D.N. Long-chain fatty acids and their acyl-CoA esters cause the translocation of phosphatidate phosphohydrolase from the cytosolic to the microsomal fraction of rat liver. FEBS Lett 1984, 175(2):284-288.
-
(1984)
FEBS Lett
, vol.175
, Issue.2
, pp. 284-288
-
-
Martin-Sanz, P.1
Hopewell, R.2
Brindley, D.N.3
-
137
-
-
0021354540
-
Oleic acid promotes the activation and translocation of phosphatidate phosphohydrolase from the cytosol to particulate fractions of isolated rat hepatocytes
-
Cascales C., Mangiapane E.H., Brindley D.N. Oleic acid promotes the activation and translocation of phosphatidate phosphohydrolase from the cytosol to particulate fractions of isolated rat hepatocytes. Biochem J 1984, 219(3):911-916.
-
(1984)
Biochem J
, vol.219
, Issue.3
, pp. 911-916
-
-
Cascales, C.1
Mangiapane, E.H.2
Brindley, D.N.3
-
138
-
-
0035798670
-
Increased rates of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats
-
Luiken J.J., Arumugam Y., Dyck D.J., et al. Increased rates of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats. J Biol Chem 2001, 276(44):40567-40573.
-
(2001)
J Biol Chem
, vol.276
, Issue.44
, pp. 40567-40573
-
-
Luiken, J.J.1
Arumugam, Y.2
Dyck, D.J.3
-
139
-
-
70349291072
-
Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cells
-
Liu G.H., Gerace L. Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cells. PLoS One 2009, 4(9):e7031.
-
(2009)
PLoS One
, vol.4
, Issue.9
-
-
Liu, G.H.1
Gerace, L.2
-
140
-
-
77950467109
-
Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes
-
Peterfy M., Harris T.E., Fujita N., et al. Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes. J Biol Chem 2010, 285(6):3857-3864.
-
(2010)
J Biol Chem
, vol.285
, Issue.6
, pp. 3857-3864
-
-
Peterfy, M.1
Harris, T.E.2
Fujita, N.3
-
141
-
-
50049105600
-
Glucocorticoids and cyclic AMP selectively increase hepatic lipin-1 expression, and insulin acts antagonistically
-
Manmontri B., Sariahmetoglu M., Donkor J., et al. Glucocorticoids and cyclic AMP selectively increase hepatic lipin-1 expression, and insulin acts antagonistically. J Lipid Res 2008, 49(5):1056-1067.
-
(2008)
J Lipid Res
, vol.49
, Issue.5
, pp. 1056-1067
-
-
Manmontri, B.1
Sariahmetoglu, M.2
Donkor, J.3
-
142
-
-
50949098238
-
Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis
-
Zhang P., O'Loughlin L., Brindley D.N., et al. Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis. J Lipid Res 2008, 49(7):1519-1528.
-
(2008)
J Lipid Res
, vol.49
, Issue.7
, pp. 1519-1528
-
-
Zhang, P.1
O'Loughlin, L.2
Brindley, D.N.3
-
143
-
-
79956293920
-
Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor gamma coactivator 1alpha/estrogen related receptor axis
-
Mitra M.S., Schilling J.D., Wang X., et al. Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor gamma coactivator 1alpha/estrogen related receptor axis. J Mol Cell Cardiol 2011, 51(1):120-128.
-
(2011)
J Mol Cell Cardiol
, vol.51
, Issue.1
, pp. 120-128
-
-
Mitra, M.S.1
Schilling, J.D.2
Wang, X.3
-
144
-
-
60649114293
-
TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1
-
Ryu D., Oh K.J., Jo H.Y., et al. TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1. Cell Metab 2009, 9(3):240-251.
-
(2009)
Cell Metab
, vol.9
, Issue.3
, pp. 240-251
-
-
Ryu, D.1
Oh, K.J.2
Jo, H.Y.3
-
145
-
-
69249084006
-
Sterol-mediated regulation of human lipin 1 gene expression in hepatoblastoma cells
-
Ishimoto K., Nakamura H., Tachibana K., et al. Sterol-mediated regulation of human lipin 1 gene expression in hepatoblastoma cells. J Biol Chem 2009, 284(33):22195-22205.
-
(2009)
J Biol Chem
, vol.284
, Issue.33
, pp. 22195-22205
-
-
Ishimoto, K.1
Nakamura, H.2
Tachibana, K.3
-
146
-
-
84856379516
-
Regulation of hepatic lipin-1 by ethanol: role of AMP-activated protein kinase/sterol regulatory element-binding protein 1 signaling in mice
-
Hu M., Wang F., Li X., et al. Regulation of hepatic lipin-1 by ethanol: role of AMP-activated protein kinase/sterol regulatory element-binding protein 1 signaling in mice. Hepatology 2012, 55(2):437-446.
-
(2012)
Hepatology
, vol.55
, Issue.2
, pp. 437-446
-
-
Hu, M.1
Wang, F.2
Li, X.3
-
147
-
-
44249088564
-
The orphan nuclear receptor, NOR-1, a target of beta-adrenergic signaling, regulates gene expression that controls oxidative metabolism in skeletal muscle
-
Pearen M.A., Myers S.A., Raichur S., et al. The orphan nuclear receptor, NOR-1, a target of beta-adrenergic signaling, regulates gene expression that controls oxidative metabolism in skeletal muscle. Endocrinology 2008, 149(6):2853-2865.
-
(2008)
Endocrinology
, vol.149
, Issue.6
, pp. 2853-2865
-
-
Pearen, M.A.1
Myers, S.A.2
Raichur, S.3
-
148
-
-
80055085369
-
Estrogen-related receptor gamma (ERRgamma) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling
-
Kim D.K., Kim J.R., Koh M., et al. Estrogen-related receptor gamma (ERRgamma) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling. J Biol Chem 2011, 286(44):38035-38042.
-
(2011)
J Biol Chem
, vol.286
, Issue.44
, pp. 38035-38042
-
-
Kim, D.K.1
Kim, J.R.2
Koh, M.3
-
149
-
-
70349947074
-
Suppression of cardiac phosphatidate phosphohydrolase 1 activity and lipin mRNA expression in Zucker diabetic fatty rats and humans with type 2 diabetes mellitus
-
Burgdorf C., Hansel L., Heidbreder M., et al. Suppression of cardiac phosphatidate phosphohydrolase 1 activity and lipin mRNA expression in Zucker diabetic fatty rats and humans with type 2 diabetes mellitus. Biochem Biophys Res Commun 2009, 390(1):165-170.
-
(2009)
Biochem Biophys Res Commun
, vol.390
, Issue.1
, pp. 165-170
-
-
Burgdorf, C.1
Hansel, L.2
Heidbreder, M.3
-
150
-
-
84455161545
-
Relationship of glucose and oleate metabolism to cardiac function in lipin-1 deficient (fld) mice
-
[Epub 2011 Nov 5]
-
Kok B.P., Kienesberger P.C., Dyck J.R., et al. Relationship of glucose and oleate metabolism to cardiac function in lipin-1 deficient (fld) mice. J Lipid Res 2012, 53(1):105-118. [Epub 2011 Nov 5].
-
(2012)
J Lipid Res
, vol.53
, Issue.1
, pp. 105-118
-
-
Kok, B.P.1
Kienesberger, P.C.2
Dyck, J.R.3
-
151
-
-
44649128516
-
Diacylglycerol acyltransferases: potential roles as pharmacological targets
-
Zammit V.A., Buckett L.K., Turnbull A.V., et al. Diacylglycerol acyltransferases: potential roles as pharmacological targets. Pharmacol Ther 2008, 118(3):295-302.
-
(2008)
Pharmacol Ther
, vol.118
, Issue.3
, pp. 295-302
-
-
Zammit, V.A.1
Buckett, L.K.2
Turnbull, A.V.3
-
152
-
-
58149457426
-
Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis
-
Yen C.L., Stone S.J., Koliwad S., et al. Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis. J Lipid Res 2008, 49(11):2283-2301.
-
(2008)
J Lipid Res
, vol.49
, Issue.11
, pp. 2283-2301
-
-
Yen, C.L.1
Stone, S.J.2
Koliwad, S.3
-
153
-
-
33845977414
-
Membrane topology and identification of key functional amino acid residues of murine acyl-CoA:diacylglycerol acyltransferase-2
-
Stone S.J., Levin M.C., Farese R.V. Membrane topology and identification of key functional amino acid residues of murine acyl-CoA:diacylglycerol acyltransferase-2. J Biol Chem 2006, 281(52):40273-40282.
-
(2006)
J Biol Chem
, vol.281
, Issue.52
, pp. 40273-40282
-
-
Stone, S.J.1
Levin, M.C.2
Farese, R.V.3
-
154
-
-
64149132208
-
The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria
-
Stone S.J., Levin M.C., Zhou P., et al. The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria. J Biol Chem 2009, 284(8):5352-5361.
-
(2009)
J Biol Chem
, vol.284
, Issue.8
, pp. 5352-5361
-
-
Stone, S.J.1
Levin, M.C.2
Zhou, P.3
-
155
-
-
80051522307
-
Murine diacylglycerol acyltransferase-2 (DGAT2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum
-
McFie P.J., Banman S.L., Kary S., et al. Murine diacylglycerol acyltransferase-2 (DGAT2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum. J Biol Chem 2011, 286(32):28235-28246.
-
(2011)
J Biol Chem
, vol.286
, Issue.32
, pp. 28235-28246
-
-
McFie, P.J.1
Banman, S.L.2
Kary, S.3
-
156
-
-
79953297691
-
DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes
-
Harris C.A., Haas J.T., Streeper R.S., et al. DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes. J Lipid Res 2011, 52(4):657-667.
-
(2011)
J Lipid Res
, vol.52
, Issue.4
, pp. 657-667
-
-
Harris, C.A.1
Haas, J.T.2
Streeper, R.S.3
-
157
-
-
24744443740
-
The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters
-
Yen C.L., Monetti M., Burri B.J., et al. The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters. J Lipid Res 2005, 46(7):1502-1511.
-
(2005)
J Lipid Res
, vol.46
, Issue.7
, pp. 1502-1511
-
-
Yen, C.L.1
Monetti, M.2
Burri, B.J.3
-
158
-
-
63249133298
-
Retinol esterification by DGAT1 is essential for retinoid homeostasis in murine skin
-
Shih M.Y., Kane M.A., Zhou P., et al. Retinol esterification by DGAT1 is essential for retinoid homeostasis in murine skin. J Biol Chem 2009, 284(7):4292-4299.
-
(2009)
J Biol Chem
, vol.284
, Issue.7
, pp. 4292-4299
-
-
Shih, M.Y.1
Kane, M.A.2
Zhou, P.3
-
159
-
-
1642523683
-
Lipopenia and skin barrier abnormalities in DGAT2-deficient mice
-
Stone S.J., Myers H.M., Watkins S.M., et al. Lipopenia and skin barrier abnormalities in DGAT2-deficient mice. J Biol Chem 2004, 279(12):11767-11776.
-
(2004)
J Biol Chem
, vol.279
, Issue.12
, pp. 11767-11776
-
-
Stone, S.J.1
Myers, H.M.2
Watkins, S.M.3
-
160
-
-
70350545945
-
Paradoxical coupling of triglyceride synthesis and fatty acid oxidation in skeletal muscle overexpressing DGAT1
-
Liu L., Shi X., Choi C.S., et al. Paradoxical coupling of triglyceride synthesis and fatty acid oxidation in skeletal muscle overexpressing DGAT1. Diabetes 2009, 58(11):2516-2524.
-
(2009)
Diabetes
, vol.58
, Issue.11
, pp. 2516-2524
-
-
Liu, L.1
Shi, X.2
Choi, C.S.3
-
161
-
-
73649094432
-
DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity
-
Liu L., Shi X., Bharadwaj K.G., et al. DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity. J Biol Chem 2009, 284(52):36312-36323.
-
(2009)
J Biol Chem
, vol.284
, Issue.52
, pp. 36312-36323
-
-
Liu, L.1
Shi, X.2
Bharadwaj, K.G.3
-
162
-
-
37149002213
-
Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle
-
Levin M.C., Monetti M., Watt M.J., et al. Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle. Am J Physiol Endocrinol Metab 2007, 293(6):E1772-E1781.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
, Issue.6
-
-
Levin, M.C.1
Monetti, M.2
Watt, M.J.3
-
163
-
-
34347235098
-
Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver
-
Monetti M., Levin M.C., Watt M.J., et al. Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. Cell Metab 2007, 6(1):69-78.
-
(2007)
Cell Metab
, vol.6
, Issue.1
, pp. 69-78
-
-
Monetti, M.1
Levin, M.C.2
Watt, M.J.3
-
164
-
-
34249894505
-
Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance
-
Liu L., Zhang Y., Chen N., et al. Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance. J Clin Invest 2007, 117(6):1679-1689.
-
(2007)
J Clin Invest
, vol.117
, Issue.6
, pp. 1679-1689
-
-
Liu, L.1
Zhang, Y.2
Chen, N.3
-
165
-
-
79551498811
-
A murine model of isolated cardiac steatosis leads to cardiomyopathy
-
Glenn D.J., Wang F., Nishimoto M., et al. A murine model of isolated cardiac steatosis leads to cardiomyopathy. Hypertension 2011, 57(2):216-222.
-
(2011)
Hypertension
, vol.57
, Issue.2
, pp. 216-222
-
-
Glenn, D.J.1
Wang, F.2
Nishimoto, M.3
-
166
-
-
33746640458
-
Mitochondrial uncoupling: a key contributor to reduced cardiac efficiency in diabetes
-
Boudina S., Abel E.D. Mitochondrial uncoupling: a key contributor to reduced cardiac efficiency in diabetes. Physiology (Bethesda) 2006, 21:250-258.
-
(2006)
Physiology (Bethesda)
, vol.21
, pp. 250-258
-
-
Boudina, S.1
Abel, E.D.2
-
167
-
-
18844376847
-
Effect of BM 17.0744, a PPARalpha ligand, on the metabolism of perfused hearts from control and diabetic mice
-
Aasum E., Cooper M., Severson D.L., et al. Effect of BM 17.0744, a PPARalpha ligand, on the metabolism of perfused hearts from control and diabetic mice. Can J Physiol Pharmacol 2005, 83(2):183-190.
-
(2005)
Can J Physiol Pharmacol
, vol.83
, Issue.2
, pp. 183-190
-
-
Aasum, E.1
Cooper, M.2
Severson, D.L.3
-
168
-
-
35448950503
-
Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America
-
Szczepaniak L.S., Victor R.G., Orci L., et al. Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America. Circ Res 2007, 101(8):759-767.
-
(2007)
Circ Res
, vol.101
, Issue.8
, pp. 759-767
-
-
Szczepaniak, L.S.1
Victor, R.G.2
Orci, L.3
-
170
-
-
49849098602
-
Adaptation and maladaptation of the heart in obesity
-
Harmancey R., Wilson C.R., Taegtmeyer H. Adaptation and maladaptation of the heart in obesity. Hypertension 2008, 52(2):181-187.
-
(2008)
Hypertension
, vol.52
, Issue.2
, pp. 181-187
-
-
Harmancey, R.1
Wilson, C.R.2
Taegtmeyer, H.3
-
171
-
-
67651216388
-
Sarcolemmal fatty acid uptake vs. mitochondrial beta-oxidation as target to regress cardiac insulin resistance
-
Luiken J.J. Sarcolemmal fatty acid uptake vs. mitochondrial beta-oxidation as target to regress cardiac insulin resistance. Appl Physiol Nutr Metab 2009, 34(3):473-480.
-
(2009)
Appl Physiol Nutr Metab
, vol.34
, Issue.3
, pp. 473-480
-
-
Luiken, J.J.1
-
172
-
-
0035061419
-
A novel mouse model of lipotoxic cardiomyopathy
-
Chiu H.C., Kovacs A., Ford D.A., et al. A novel mouse model of lipotoxic cardiomyopathy. J Clin Invest 2001, 107(7):813-822.
-
(2001)
J Clin Invest
, vol.107
, Issue.7
, pp. 813-822
-
-
Chiu, H.C.1
Kovacs, A.2
Ford, D.A.3
-
173
-
-
0038509036
-
Lipotoxicity: when tissues overeat
-
Schaffer J.E. Lipotoxicity: when tissues overeat. Curr Opin Lipidol 2003, 14(3):281-287.
-
(2003)
Curr Opin Lipidol
, vol.14
, Issue.3
, pp. 281-287
-
-
Schaffer, J.E.1
-
174
-
-
70449133334
-
Diabetes and apoptosis: lipotoxicity
-
Kusminski C.M., Shetty S., Orci L., et al. Diabetes and apoptosis: lipotoxicity. Apoptosis 2009, 14(12):1484-1495.
-
(2009)
Apoptosis
, vol.14
, Issue.12
, pp. 1484-1495
-
-
Kusminski, C.M.1
Shetty, S.2
Orci, L.3
-
175
-
-
76349119251
-
Lipotoxicity in the heart
-
[Epub 2009 Oct 8]
-
Wende A.R., Abel E.D. Lipotoxicity in the heart. Biochim Biophys Acta 2010, 1801(3):311-319. [Epub 2009 Oct 8].
-
(2010)
Biochim Biophys Acta
, vol.1801
, Issue.3
, pp. 311-319
-
-
Wende, A.R.1
Abel, E.D.2
-
176
-
-
0033673142
-
A metabolic role for mitochondria in palmitate-induced cardiac myocyte apoptosis
-
Sparagna G.C., Hickson-Bick D.L., Buja L.M., et al. A metabolic role for mitochondria in palmitate-induced cardiac myocyte apoptosis. Am J Physiol Heart Circ Physiol 2000, 279(5):H2124-H2132.
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.279
, Issue.5
-
-
Sparagna, G.C.1
Hickson-Bick, D.L.2
Buja, L.M.3
-
177
-
-
45549102437
-
Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells
-
Coll T., Eyre E., Rodriguez-Calvo R., et al. Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells. J Biol Chem 2008, 283(17):11107-11116.
-
(2008)
J Biol Chem
, vol.283
, Issue.17
, pp. 11107-11116
-
-
Coll, T.1
Eyre, E.2
Rodriguez-Calvo, R.3
-
178
-
-
0142164965
-
Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes
-
Chavez J.A., Summers S.A. Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes. Arch Biochem Biophys 2003, 419(2):101-109.
-
(2003)
Arch Biochem Biophys
, vol.419
, Issue.2
, pp. 101-109
-
-
Chavez, J.A.1
Summers, S.A.2
-
179
-
-
4544242908
-
Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells
-
Powell D.J., Turban S., Gray A., et al. Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells. Biochem J 2004, 382(Pt 2):619-629.
-
(2004)
Biochem J
, vol.382
, Issue.PART 2
, pp. 619-629
-
-
Powell, D.J.1
Turban, S.2
Gray, A.3
-
180
-
-
11144346132
-
Mouse models of mitochondrial dysfunction and heart failure
-
Russell L.K., Finck B.N., Kelly D.P. Mouse models of mitochondrial dysfunction and heart failure. J Mol Cell Cardiol 2005, 38(1):81-91.
-
(2005)
J Mol Cell Cardiol
, vol.38
, Issue.1
, pp. 81-91
-
-
Russell, L.K.1
Finck, B.N.2
Kelly, D.P.3
-
181
-
-
72249100585
-
Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function
-
Basu R., Oudit G.Y., Wang X., et al. Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function. Am J Physiol Heart Circ Physiol 2009, 297(6):H2096-H2108.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
, Issue.6
-
-
Basu, R.1
Oudit, G.Y.2
Wang, X.3
-
182
-
-
78650481257
-
Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation
-
Zhang L., Ussher J.R., Oka T., et al. Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation. Cardiovasc Res 2011, 89(1):148-156.
-
(2011)
Cardiovasc Res
, vol.89
, Issue.1
, pp. 148-156
-
-
Zhang, L.1
Ussher, J.R.2
Oka, T.3
-
183
-
-
54249093047
-
Ceramide is a cardiotoxin in lipotoxic cardiomyopathy
-
Park T.S., Hu Y., Noh H.L., et al. Ceramide is a cardiotoxin in lipotoxic cardiomyopathy. J Lipid Res 2008, 49(10):2101-2112.
-
(2008)
J Lipid Res
, vol.49
, Issue.10
, pp. 2101-2112
-
-
Park, T.S.1
Hu, Y.2
Noh, H.L.3
-
184
-
-
79952175806
-
Cardiomyocyte lipids impair beta-adrenergic receptor function via PKC activation
-
Drosatos K., Bharadwaj K.G., Lymperopoulos A., et al. Cardiomyocyte lipids impair beta-adrenergic receptor function via PKC activation. Am J Physiol Endocrinol Metab 2011, 300(3):E489-E499.
-
(2011)
Am J Physiol Endocrinol Metab
, vol.300
, Issue.3
-
-
Drosatos, K.1
Bharadwaj, K.G.2
Lymperopoulos, A.3
-
185
-
-
21244492310
-
Myocardial substrate metabolism in the normal and failing heart
-
Stanley W.C., Recchia F.A., Lopaschuk G.D. Myocardial substrate metabolism in the normal and failing heart. Physiol Rev 2005, 85(3):1093-1129.
-
(2005)
Physiol Rev
, vol.85
, Issue.3
, pp. 1093-1129
-
-
Stanley, W.C.1
Recchia, F.A.2
Lopaschuk, G.D.3
-
186
-
-
0025821485
-
Myocardial triglyceride turnover and contribution to energy substrate utilization in isolated working rat hearts
-
Saddik M., Lopaschuk G.D. Myocardial triglyceride turnover and contribution to energy substrate utilization in isolated working rat hearts. J Biol Chem 1991, 266(13):8162-8170.
-
(1991)
J Biol Chem
, vol.266
, Issue.13
, pp. 8162-8170
-
-
Saddik, M.1
Lopaschuk, G.D.2
-
187
-
-
77955176286
-
Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha
-
Banke N.H., Wende A.R., Leone T.C., et al. Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha. Circ Res 2010, 107(2):233-241.
-
(2010)
Circ Res
, vol.107
, Issue.2
, pp. 233-241
-
-
Banke, N.H.1
Wende, A.R.2
Leone, T.C.3
-
188
-
-
0031439257
-
Effects of adrenaline on triacylglycerol synthesis and turnover in ventricular myocytes from adult rats
-
Swanton E.M., Saggerson E.D. Effects of adrenaline on triacylglycerol synthesis and turnover in ventricular myocytes from adult rats. Biochem J 1997, 328(Pt 3):913-922.
-
(1997)
Biochem J
, vol.328
, Issue.PART 3
, pp. 913-922
-
-
Swanton, E.M.1
Saggerson, E.D.2
-
189
-
-
84858020291
-
FAT SIGNALS-lipases and lipolysis in lipid metabolism and signaling
-
Zechner R., Zimmermann R., Eichmann T.O., et al. FAT SIGNALS-lipases and lipolysis in lipid metabolism and signaling. Cell Metab 2012, 15(3):279-291.
-
(2012)
Cell Metab
, vol.15
, Issue.3
, pp. 279-291
-
-
Zechner, R.1
Zimmermann, R.2
Eichmann, T.O.3
-
190
-
-
33646462136
-
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
-
Haemmerle G., Lass A., Zimmermann R., et al. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 2006, 312(5774):734-737.
-
(2006)
Science
, vol.312
, Issue.5774
, pp. 734-737
-
-
Haemmerle, G.1
Lass, A.2
Zimmermann, R.3
-
191
-
-
0023795353
-
Hormone-sensitive lipase: sequence, expression, and chromosomal localization to 19 cent-q13.3
-
Holm C., Kirchgessner T.G., Svenson K.L., et al. Hormone-sensitive lipase: sequence, expression, and chromosomal localization to 19 cent-q13.3. Science 1988, 241(4872):1503-1506.
-
(1988)
Science
, vol.241
, Issue.4872
, pp. 1503-1506
-
-
Holm, C.1
Kirchgessner, T.G.2
Svenson, K.L.3
-
192
-
-
0035967790
-
The cloning and expression of a murine triacylglycerol hydrolase cDNA and the structure of its corresponding gene
-
Dolinsky V.W., Sipione S., Lehner R., et al. The cloning and expression of a murine triacylglycerol hydrolase cDNA and the structure of its corresponding gene. Biochim Biophys Acta 2001, 1532(3):162-172.
-
(2001)
Biochim Biophys Acta
, vol.1532
, Issue.3
, pp. 162-172
-
-
Dolinsky, V.W.1
Sipione, S.2
Lehner, R.3
-
193
-
-
0030767295
-
CDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases
-
Karlsson M., Contreras J.A., Hellman U., et al. cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases. J Biol Chem 1997, 272(43):27218-27223.
-
(1997)
J Biol Chem
, vol.272
, Issue.43
, pp. 27218-27223
-
-
Karlsson, M.1
Contreras, J.A.2
Hellman, U.3
-
194
-
-
33646128723
-
Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman syndrome
-
Lass A., Zimmermann R., Haemmerle G., et al. Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman syndrome. Cell Metab 2006, 3(5):309-319.
-
(2006)
Cell Metab
, vol.3
, Issue.5
, pp. 309-319
-
-
Lass, A.1
Zimmermann, R.2
Haemmerle, G.3
-
195
-
-
77950620338
-
Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids
-
Schoiswohl G., Schweiger M., Schreiber R., et al. Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids. J Lipid Res 2010, 51(3):490-499.
-
(2010)
J Lipid Res
, vol.51
, Issue.3
, pp. 490-499
-
-
Schoiswohl, G.1
Schweiger, M.2
Schreiber, R.3
-
196
-
-
80052454265
-
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1
-
Haemmerle G., Moustafa T., Woelkart G., et al. ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1. Nat Med 2011, 17(9):1076-1085.
-
(2011)
Nat Med
, vol.17
, Issue.9
, pp. 1076-1085
-
-
Haemmerle, G.1
Moustafa, T.2
Woelkart, G.3
-
197
-
-
76649123086
-
Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators
-
Duncan J.G., Bharadwaj K.G., Fong J.L., et al. Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators. Circulation 2010, 121(3):426-435.
-
(2010)
Circulation
, vol.121
, Issue.3
, pp. 426-435
-
-
Duncan, J.G.1
Bharadwaj, K.G.2
Fong, J.L.3
-
198
-
-
68049092870
-
Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5
-
Schweiger M., Lass A., Zimmermann R., et al. Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5. Am J Physiol Endocrinol Metab 2009, 297(2):E289-E296.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.297
, Issue.2
-
-
Schweiger, M.1
Lass, A.2
Zimmermann, R.3
-
199
-
-
57149097132
-
Triglyceride deposit cardiomyovasculopathy
-
Hirano K., Ikeda Y., Zaima N., et al. Triglyceride deposit cardiomyovasculopathy. N Engl J Med 2008, 359(22):2396-2398.
-
(2008)
N Engl J Med
, vol.359
, Issue.22
, pp. 2396-2398
-
-
Hirano, K.1
Ikeda, Y.2
Zaima, N.3
-
200
-
-
0037085450
-
Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis
-
Haemmerle G., Zimmermann R., Hayn M., et al. Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis. J Biol Chem 2002, 277(7):4806-4815.
-
(2002)
J Biol Chem
, vol.277
, Issue.7
, pp. 4806-4815
-
-
Haemmerle, G.1
Zimmermann, R.2
Hayn, M.3
-
201
-
-
20544449419
-
Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart
-
Park S.Y., Kim H.J., Wang S., et al. Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart. Am J Physiol Endocrinol Metab 2005, 289(1):E30-E39.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
, Issue.1
-
-
Park, S.Y.1
Kim, H.J.2
Wang, S.3
-
202
-
-
0344667491
-
Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormone-sensitive lipase-deficient white adipose tissue
-
Zimmermann R., Haemmerle G., Wagner E.M., et al. Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormone-sensitive lipase-deficient white adipose tissue. J Lipid Res 2003, 44(11):2089-2099.
-
(2003)
J Lipid Res
, vol.44
, Issue.11
, pp. 2089-2099
-
-
Zimmermann, R.1
Haemmerle, G.2
Wagner, E.M.3
-
203
-
-
0034795268
-
Absence of cardiac lipid accumulation in transgenic mice with heart-specific HSL overexpression
-
Suzuki J., Shen W.J., Nelson B.D., et al. Absence of cardiac lipid accumulation in transgenic mice with heart-specific HSL overexpression. Am J Physiol Endocrinol Metab 2001, 281(4):E857-E866.
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
, Issue.4
-
-
Suzuki, J.1
Shen, W.J.2
Nelson, B.D.3
-
204
-
-
47549089671
-
Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice
-
Ueno M., Suzuki J., Zenimaru Y., et al. Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice. Am J Physiol Endocrinol Metab 2008, 294(6):E1109-E1118.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
, Issue.6
-
-
Ueno, M.1
Suzuki, J.2
Zenimaru, Y.3
-
205
-
-
84856807853
-
Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction
-
Kienesberger P.C., Pulinilkunnil T., Sung M.M., et al. Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction. Mol Cell Biol 2012, 32(4):740-750.
-
(2012)
Mol Cell Biol
, vol.32
, Issue.4
, pp. 740-750
-
-
Kienesberger, P.C.1
Pulinilkunnil, T.2
Sung, M.M.3
-
206
-
-
79955958008
-
Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance
-
Taschler U., Radner F.P., Heier C., et al. Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. J Biol Chem 2011, 286(20):17467-17477.
-
(2011)
J Biol Chem
, vol.286
, Issue.20
, pp. 17467-17477
-
-
Taschler, U.1
Radner, F.P.2
Heier, C.3
-
207
-
-
0141818124
-
Inhibitors of hepatic microsomal triacylglycerol hydrolase decrease very low density lipoprotein secretion
-
Gilham D., Ho S., Rasouli M., et al. Inhibitors of hepatic microsomal triacylglycerol hydrolase decrease very low density lipoprotein secretion. FASEB J 2003, 17(12):1685-1687.
-
(2003)
FASEB J
, vol.17
, Issue.12
, pp. 1685-1687
-
-
Gilham, D.1
Ho, S.2
Rasouli, M.3
-
208
-
-
37249076416
-
Apolipoprotein B and triacylglycerol secretion in human triacylglycerol hydrolase transgenic mice
-
Wei E., Alam M., Sun F., et al. Apolipoprotein B and triacylglycerol secretion in human triacylglycerol hydrolase transgenic mice. J Lipid Res 2007, 48(12):2597-2606.
-
(2007)
J Lipid Res
, vol.48
, Issue.12
, pp. 2597-2606
-
-
Wei, E.1
Alam, M.2
Sun, F.3
-
209
-
-
65449137930
-
Cardiac expression of microsomal triglyceride transfer protein is increased in obesity and serves to attenuate cardiac triglyceride accumulation
-
Bartels E.D., Nielsen J.M., Hellgren L.I., et al. Cardiac expression of microsomal triglyceride transfer protein is increased in obesity and serves to attenuate cardiac triglyceride accumulation. PLoS One 2009, 4(4):e5300.
-
(2009)
PLoS One
, vol.4
, Issue.4
-
-
Bartels, E.D.1
Nielsen, J.M.2
Hellgren, L.I.3
-
210
-
-
2642660445
-
Apo B100-containing lipoproteins are secreted by the heart
-
Boren J., Veniant M.M., Young S.G. Apo B100-containing lipoproteins are secreted by the heart. J Clin Invest 1998, 101(6):1197-1202.
-
(1998)
J Clin Invest
, vol.101
, Issue.6
, pp. 1197-1202
-
-
Boren, J.1
Veniant, M.M.2
Young, S.G.3
-
211
-
-
0021864482
-
Two mechanisms produce tissue-specific inhibition of fatty acid oxidation by oxfenicine
-
Stephens T.W., Higgins A.J., Cook G.A., et al. Two mechanisms produce tissue-specific inhibition of fatty acid oxidation by oxfenicine. Biochem J 1985, 227(2):651-660.
-
(1985)
Biochem J
, vol.227
, Issue.2
, pp. 651-660
-
-
Stephens, T.W.1
Higgins, A.J.2
Cook, G.A.3
-
212
-
-
1542496389
-
Short- and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy
-
Fragasso G., Piatti Md P.M., Monti L., et al. Short- and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy. Am Heart J 2003, 146(5):E18.
-
(2003)
Am Heart J
, vol.146
, Issue.5
-
-
Fragasso, G.1
Piatti Md, P.M.2
Monti, L.3
-
213
-
-
4944224833
-
Trimetazidine improves left ventricular function and quality of life in elderly patients with coronary artery disease
-
Vitale C., Wajngaten M., Sposato B., et al. Trimetazidine improves left ventricular function and quality of life in elderly patients with coronary artery disease. Eur Heart J 2004, 25(20):1814-1821.
-
(2004)
Eur Heart J
, vol.25
, Issue.20
, pp. 1814-1821
-
-
Vitale, C.1
Wajngaten, M.2
Sposato, B.3
-
214
-
-
0034678082
-
The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase
-
Kantor P.F., Lucien A., Kozak R., et al. The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. Circ Res 2000, 86(5):580-588.
-
(2000)
Circ Res
, vol.86
, Issue.5
, pp. 580-588
-
-
Kantor, P.F.1
Lucien, A.2
Kozak, R.3
-
215
-
-
0036936426
-
Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure
-
Sabbah H.N., Chandler M.P., Mishima T., et al. Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure. J Card Fail 2002, 8(6):416-422.
-
(2002)
J Card Fail
, vol.8
, Issue.6
, pp. 416-422
-
-
Sabbah, H.N.1
Chandler, M.P.2
Mishima, T.3
-
216
-
-
33744455453
-
Ranolazine for the treatment of chronic angina and potential use in other cardiovascular conditions
-
Chaitman B.R. Ranolazine for the treatment of chronic angina and potential use in other cardiovascular conditions. Circulation 2006, 113(20):2462-2472.
-
(2006)
Circulation
, vol.113
, Issue.20
, pp. 2462-2472
-
-
Chaitman, B.R.1
-
217
-
-
33745822073
-
Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents
-
Cheng J.F., Huang Y., Penuliar R., et al. Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents. J Med Chem 2006, 49(14):4055-4058.
-
(2006)
J Med Chem
, vol.49
, Issue.14
, pp. 4055-4058
-
-
Cheng, J.F.1
Huang, Y.2
Penuliar, R.3
-
218
-
-
0034644442
-
Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: a randomized trial. Arterial Disease Multiple Intervention Trial
-
Elam M.B., Hunninghake D.B., Davis K.B., et al. Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: a randomized trial. Arterial Disease Multiple Intervention Trial. JAMA 2000, 284(10):1263-1270.
-
(2000)
JAMA
, vol.284
, Issue.10
, pp. 1263-1270
-
-
Elam, M.B.1
Hunninghake, D.B.2
Davis, K.B.3
-
219
-
-
72049129430
-
Extended-release niacin or ezetimibe and carotid intima-media thickness
-
Taylor A.J., Villines T.C., Stanek E.J., et al. Extended-release niacin or ezetimibe and carotid intima-media thickness. N Engl J Med 2009, 361(22):2113-2122.
-
(2009)
N Engl J Med
, vol.361
, Issue.22
, pp. 2113-2122
-
-
Taylor, A.J.1
Villines, T.C.2
Stanek, E.J.3
-
220
-
-
20444371945
-
The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)
-
Garcia-Calvo M., Lisnock J., Bull H.G., et al. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1). Proc Natl Acad Sci U S A 2005, 102(23):8132-8137.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.23
, pp. 8132-8137
-
-
Garcia-Calvo, M.1
Lisnock, J.2
Bull, H.G.3
-
221
-
-
0028913896
-
Metformin. A review of its pharmacological properties and therapeutic use in non-insulin-dependent diabetes mellitus
-
Dunn C.J., Peters D.H. Metformin. A review of its pharmacological properties and therapeutic use in non-insulin-dependent diabetes mellitus. Drugs 1995, 49(5):721-749.
-
(1995)
Drugs
, vol.49
, Issue.5
, pp. 721-749
-
-
Dunn, C.J.1
Peters, D.H.2
-
222
-
-
34548609993
-
Systematic review: comparative effectiveness and safety of oral medications for type 2 diabetes mellitus
-
Bolen S., Feldman L., Vassy J., et al. Systematic review: comparative effectiveness and safety of oral medications for type 2 diabetes mellitus. Ann Intern Med 2007, 147(6):386-399.
-
(2007)
Ann Intern Med
, vol.147
, Issue.6
, pp. 386-399
-
-
Bolen, S.1
Feldman, L.2
Vassy, J.3
-
223
-
-
70349342714
-
Effect of fibrates on lipid profiles and cardiovascular outcomes: a systematic review
-
e1-8
-
Abourbih S., Filion K.B., Joseph L., et al. Effect of fibrates on lipid profiles and cardiovascular outcomes: a systematic review. Am J Med 2009, 122(10):962. e1-8.
-
(2009)
Am J Med
, vol.122
, Issue.10
, pp. 962
-
-
Abourbih, S.1
Filion, K.B.2
Joseph, L.3
-
224
-
-
33645730513
-
Cardioprotective properties of fibrates: which fibrate, which patients, what mechanism?
-
Barter P.J., Rye K.A. Cardioprotective properties of fibrates: which fibrate, which patients, what mechanism?. Circulation 2006, 113(12):1553-1555.
-
(2006)
Circulation
, vol.113
, Issue.12
, pp. 1553-1555
-
-
Barter, P.J.1
Rye, K.A.2
-
225
-
-
0037490080
-
Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis
-
Law M.R., Wald N.J., Rudnicka A.R. Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. BMJ 2003, 326(7404):1423.
-
(2003)
BMJ
, vol.326
, Issue.7404
, pp. 1423
-
-
Law, M.R.1
Wald, N.J.2
Rudnicka, A.R.3
-
226
-
-
0030802435
-
Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials
-
Hebert P.R., Gaziano J.M., Chan K.S., et al. Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials. JAMA 1997, 278(4):313-321.
-
(1997)
JAMA
, vol.278
, Issue.4
, pp. 313-321
-
-
Hebert, P.R.1
Gaziano, J.M.2
Chan, K.S.3
-
227
-
-
53049107359
-
Reassessing the cardiovascular risks and benefits of thiazolidinediones
-
Zinn A., Felson S., Fisher E., et al. Reassessing the cardiovascular risks and benefits of thiazolidinediones. Clin Cardiol 2008, 31(9):397-403.
-
(2008)
Clin Cardiol
, vol.31
, Issue.9
, pp. 397-403
-
-
Zinn, A.1
Felson, S.2
Fisher, E.3
-
228
-
-
52949126757
-
Thiazolidinediones in type 2 diabetes: a cardiology perspective
-
Khanderia U., Pop-Busui R., Eagle K.A. Thiazolidinediones in type 2 diabetes: a cardiology perspective. Ann Pharmacother 2008, 42(10):1466-1474.
-
(2008)
Ann Pharmacother
, vol.42
, Issue.10
, pp. 1466-1474
-
-
Khanderia, U.1
Pop-Busui, R.2
Eagle, K.A.3
-
229
-
-
12744271862
-
Myocardial metabolic manipulation: a new therapeutic approach in heart failure?
-
O'Meara E., McMurray J.J. Myocardial metabolic manipulation: a new therapeutic approach in heart failure?. Heart 2005, 91(2):131-132.
-
(2005)
Heart
, vol.91
, Issue.2
, pp. 131-132
-
-
O'Meara, E.1
McMurray, J.J.2
-
230
-
-
4344697195
-
Cardiac metabolism as a target for the treatment of heart failure
-
Taegtmeyer H. Cardiac metabolism as a target for the treatment of heart failure. Circulation 2004, 110(8):894-896.
-
(2004)
Circulation
, vol.110
, Issue.8
, pp. 894-896
-
-
Taegtmeyer, H.1
-
231
-
-
67649209841
-
Increased glucose uptake and oxidation in mouse hearts prevent high fatty acid oxidation but cause cardiac dysfunction in diet-induced obesity
-
Yan J., Young M.E., Cui L., et al. Increased glucose uptake and oxidation in mouse hearts prevent high fatty acid oxidation but cause cardiac dysfunction in diet-induced obesity. Circulation 2009, 119(21):2818-2828.
-
(2009)
Circulation
, vol.119
, Issue.21
, pp. 2818-2828
-
-
Yan, J.1
Young, M.E.2
Cui, L.3
-
232
-
-
33646832738
-
Loss of lipoprotein lipase-derived fatty acids leads to increased cardiac glucose metabolism and heart dysfunction
-
Augustus A.S., Buchanan J., Park T.S., et al. Loss of lipoprotein lipase-derived fatty acids leads to increased cardiac glucose metabolism and heart dysfunction. J Biol Chem 2006, 281(13):8716-8723.
-
(2006)
J Biol Chem
, vol.281
, Issue.13
, pp. 8716-8723
-
-
Augustus, A.S.1
Buchanan, J.2
Park, T.S.3
-
233
-
-
41649098889
-
Management of mixed dyslipidemia in patients with or at risk for cardiovascular disease: a role for combination fibrate therapy
-
Fazio S. Management of mixed dyslipidemia in patients with or at risk for cardiovascular disease: a role for combination fibrate therapy. Clin Ther 2008, 30(2):294-306.
-
(2008)
Clin Ther
, vol.30
, Issue.2
, pp. 294-306
-
-
Fazio, S.1
-
234
-
-
0035969564
-
Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease
-
Brown B.G., Zhao X.Q., Chait A., et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001, 345(22):1583-1592.
-
(2001)
N Engl J Med
, vol.345
, Issue.22
, pp. 1583-1592
-
-
Brown, B.G.1
Zhao, X.Q.2
Chait, A.3
-
235
-
-
9644252909
-
Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs
-
Graham D.J., Staffa J.A., Shatin D., et al. Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs. JAMA 2004, 292(21):2585-2590.
-
(2004)
JAMA
, vol.292
, Issue.21
, pp. 2585-2590
-
-
Graham, D.J.1
Staffa, J.A.2
Shatin, D.3
|