Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese Zucker rats

Diabetes

Volumn 53, Issue 7, 2004, Pages 1655-1663

  Coort, Susan L M ^a   Hasselbaink, Danny M ^a   Koonen, Debby P Y ^a   Willems, Jodil ^a   Coumans, Will A ^a   Chabowski, Adrian ^b   Van Der Vusse, Ger J ^a   Bonen, Arenal ^b   Glatz, Jan F C ^a   Luiken, Joost J F P ^a,c  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF GUELPH   (Canada)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; CARRIER PROTEIN; CD36 ANTIGEN; INSULIN; LONG CHAIN FATTY ACID; OLIGOMYCIN; SUCCINIMIDE DERIVATIVE; SULFO N SUCCINIMIDYLOLEATE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOMYOPATHY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ESTERIFICATION; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; FEMALE; HEART CONTRACTION; HEART MUSCLE CELL; HORMONAL REGULATION; HYPERINSULINEMIA; LEAN BODY WEIGHT; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT STRAIN; SARCOLEMMA; STIMULATION; STORAGE;

ANIMALS; ANTIGENS, CD36; BIOLOGICAL TRANSPORT; ESTERIFICATION; FATTY ACIDS; FEMALE; INTRACELLULAR MEMBRANES; MYOCARDIUM; MYOCYTES, CARDIAC; OBESITY; OLEIC ACIDS; OLIGOMYCINS; OXIDATION-REDUCTION; PHOSPHOLIPIDS; RATS; RATS, ZUCKER; SARCOLEMMA; SUBCELLULAR FRACTIONS; SUCCINIMIDES; THINNESS; TISSUE DISTRIBUTION; TRIGLYCERIDES;

EID: 3042739406     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.7.1655     Document Type: Article

References (43)

1. Abbasi F, Brown BW Jr, Lamendola C, McLaughlin T, Reaven GM: Relationship between obesity, insulin resistance, and coronary heart disease risk. J Am Coll Cardiol 40:937-943, 2002
2. Zhou YT, Grayburn P, Karim A, Shimabukuro M, Higa M, Baetens D, Orci L, Unger RH: Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci U S A 97:1784-1789, 2000
3. Shulman GI: Cellular mechanisms of insulin resistance. J Clin Invest 106:171-176, 2000
4. Pan DA, Lillioja S, Kriketos AD, Milner MR, Baur LA, Bogardus C, Jenkins AB, Storlien LH: Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes 46:983-988, 1997
5. Krssak M, Falk Petersen K, Dresner A, DiPietro L, Vogel SM, Rothman DL, Roden M, Shulman GI: Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia 42:113-116, 1999
6. Turcotte LP, Swenberger JR, Zavitz Tucker M, Yee AJ: Increased fatty acid uptake and altered fatty acid metabolism in insulin-resistant muscle of obese Zucker rats. Diabetes 50:1389-1396, 2001
7. Young ME, Guthrie PH, Razeghi P, Leighton B, Abbasi S, Patil S, Youker KA, Taegtmeyer H: Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart. Diabetes 51:2587-2595, 2002
8. Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, Kovacs A, Han X, Gross RW, Kozak R, Lopaschuk GD, Kelly DP: The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. J Clin Invest 109:121-130, 2002
9. Chiu HC, Kovacs A, Ford DA, Hsu FF, Garcia R, Herrero P, Saffitz JE, Schaffer JE: A novel mouse model of lipotoxic cardiomyopathy. J Clin Invest 107:813-822, 2001
10. Luiken JJ, Schaap FG, van Nieuwenhoven FA, van der Vusse GJ, Bonen A, Glatz JF: Cellular fatty acid transport in heart and skeletal muscle as facilitated by proteins. Lipids 34 (Suppl.):S169-S175, 1999
11. Luiken JJ, Turcotte LP, Bonen A: Protein-mediated palmitate uptake and expression of fatty acid transport proteins in heart giant vesicles. J Lipid Res 40:1007-1016, 1999
12. Luiken JJ, van Nieuwenhoven FA, America G, van der Vusse GJ, Glatz JF: Uptake and metabolism of palmitate by isolated cardiac myocytes from adult rats: involvement of sarcolemmal proteins. J Lipid Res 38:745-758, 1997
13. Bonen A, Luiken JJ, Arumugam Y, Glatz JF, Tandon NN: Acute regulation of fatty acid uptake involves the cellular redistribution of fatty acid translocase. J Biol Chem 275:14501-14508, 2000
14. Luiken JJ, Dyck DJ, Han X-X, Tandon NN, Arumugam Y, Glatz JF, Bonen A: Insulin induces the translocation of the fatty acid transporter FAT/CD36 to the plasma membrane. Am J Endocrinol Metab 282:E491-E495, 2002
15. Luiken JJ, Koonen DP, Willems J, Zorzano A, Becker C, Fischer Y, Tandon NN, Van Der Vusse GJ, Bonen A, Glatz JF: Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36. Diabetes 51:3113-3119, 2002
16. Luiken JJ, Willems J, van Der Vusse GJ, Glatz JF: Electrostimulation enhances FAT/CD36-mediated long-chain fatty acid uptake by isolated rat cardiac myocytes. Am J Physiol 281:E704-E712, 2001
17. Kemp BE, Mitchelhill KI, Stapleton D, Michell BJ, Chen ZP, Witters LA: Dealing with energy demand: the AMP-activated protein kinase. Trends Biochem Sci 24:22-25, 1999
18. Luiken JJ, Coort SL, Willems J, Coumans WA, Bonen A, Van Der Vusse GJ, Glatz JF: Contraction-induced fatty acid translocase/CD36 translocation in rat cardiac myocytes is mediated through AMP-activated protein kinase signaling. Diabetes 52:1627-1634, 2003
19. van der Vusse GJ, Glatz JF, Stam HC, Reneman RS: Fatty acid homeostasis in the normoxic and ischemic heart. Physiol Rev 72:881-940, 1992
20. Distel RJ, Robinson GS, Spiegelman BM: Fatty acid regulation of gene expression: transcriptional and post-transcriptional mechanisms. J Biol Chem 267:5937-5941, 1992
21. Muoio DM, Dohm GL, Tapscott EB, Coleman RA: Leptin opposes insulin's effects on fatty acid partitioning in muscles isolated from obese ob/ob mice. Am J Physiol 276:E913-E921, 1999
22. Luiken JJ, Willems J, Coort SL, Coumans WA, Bonen A, Van Der Vusse GJ, Glatz JF: Effects of cAMP modulators on long-chain fatty-acid uptake and utilization by electrically stimulated rat cardiac myocytes. Biochem J 367:881-887, 2002
23. Luiken JJ, Arumugam Y, Dyck DJ, Bell RC, Pelsers MM, Turcotte LP, Tandon NN, Glatz JF, Bonen A: Increased rates of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats. J Biol Chem 276:40567-40573, 2001
24. Harmon CM, Luce P, Beth AH, Abumrad NA: Labeling of adipocyte membranes by sulfo-N-succinimidyl derivatives of long-chain fatty acids: inhibition of fatty acid transport. J Membr Biol 121:261-268, 1991
25. Coort SL, Willems J, Coumans WA, van der Vusse GJ, Bonen A, Glatz JF, Luiken JJ: Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake. Mol Cell Biochem 239:213-219, 2002
26. Fischer Y, Rose H, Kammermeier H: Highly insulin-responsive isolated rat heart muscle cells yielded by a modified isolation method. Life Sci 49:1679-1688, 1991
27. Anjaneyulu PS, Staros JV: Reactions of N-hydroxysulfosuccinimide active esters. Int J Pept Protein Res 30:117-124, 1987
28. Richieri GV, Anel A, Kleinfeld AM: Interactions of long-chain fatty acids and albumin: determination of free fatty acid levels using the fluorescent probe ADIFAB. Biochemistry 32:7574-7580, 1993
29. Glatz JF, Jacobs AE, Veerkamp JH: Fatty acid oxidation in human and rat heart: comparison of cell-free and cellular systems. Biochim Biophys Acta 794:454-465, 1984
30. van der Vusse GJ, Roemen TH: Protein acylation in normoxic and ischemic/reperfused cardiac tissue. Prostaglandins Leukot Essent Fatty Acids 60:299-305, 1999
31. Klip A, Ramlal T, Young DA, Holloszy JO: Insulin-induced translocation of glucose transporters in rat hindlimb muscles. FEBS Lett 224:224-230, 1987
32. Fuller W, Eaton P, Medina RA, Bell J, Shattock MJ: Differential centrifugation separates cardiac sacrolemmal and endosomal membranes from Langendorff-perfused rat hearts. Anal Biochem 293:216-223, 2001
33. Havekes LM, de Wit EC, Princen HM: Cellular free cholesterol in Hep G2 cells is only partially available for down-regulation of low-density-lipoprotein receptor activity. Biochem J 247:739-746, 1987
34. Qu X, Seale JP, Donnelly R: Tissue and isoform-selective activation of protein kinase C in insulin-resistant obese Zucker rats: effects of feeding. J Endocrinol 162:207-214, 1999
35. Cooper DR, Watson JE, Dao ML: Decreased expression of protein kinase-C alpha, beta, and epsilon in soleus muscle of Zucker obese (fa/fa) rats. Endocrinology 133:2241-2247, 1993
36. Morabito D, Montessuit C, Rosenblatt-Velin N, Lerch R, Vallotton MB, Lang U: Impaired glucose metabolism in the heart of obese Zucker rats after treatment with phorbol ester. Int J Obes Relat Metab Disord 26:327-334, 2002
37. Hasselbaink DM, Glatz JF, Luiken JJ, Roemen TH, Van der Vusse GJ: Ketone bodies disturb fatty acid handling in isolated cardiomyocytes derived from control and diabetic rats. Biochem J 371:753-760, 2003
38. Kelley DE, Mandarino LJ: Fuel selection in human skeletal muscle in insulin resistance: a reexamination. Diabetes 49:677-683, 2000
39. Unger RH, Orci L: Diseases of liporegulation: new perspective on obesity and related disorders. FASEB J 15:312-321, 2001
40. Bergeron R, Previs SF, Cline GW, Perret P, Russell RR 3rd, Young LH, Shulman GI: Effect of 5-aminoinudazole-4-carboxamide-1-β-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats. Diabetes 50:1076-1082, 2001
41. Musi N, Fujii N, Hirshman MF, Ekberg I, Froberg S, Ljungqvist O, Thorell A, Goodyear LJ: AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise. Diabetes 50:921-927, 2001
42. Buhl ES, Jessen N, Pold R, Ledet T, Flyvbjerg A, Pedersen SB, Pedersen O, Schmitz O, Lund S: Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome. Diabetes 51:2199-2206, 2002
43. Merrill GF, Kurth EJ, Hardie DG, Winder WW: AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. Am J Physiol 273:E1107-E1112, 1997