Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle

American Journal of Physiology - Endocrinology and Metabolism

Volumn 293, Issue 6, 2007, Pages

  Levin, Malin C ^a   Monetti, Mara ^a   Watt, Matthew J ^b   Sajan, Mini P ^c   Stevens, Robert D ^d   Bain, James R ^d   Newgard, Christopher B ^d   Farese Sr , Robert V ^c   Farese Jr , Robert V ^a,e  

^a GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^b ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d DUKE UNIVERSITY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acyl CoA:diacylglycerol acyltransferase 2; Glycolytic fibers; Skeletal muscle; Triacylglycerols

Indexed keywords

ACYL COENZYME A; CERAMIDE DERIVATIVE; CREATINE KINASE MM; DIACYLGLYCEROL ACYLTRANSFERASE; DIACYLGLYCEROL ACYLTRANSFERASE 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GLUCOSE TRANSPORT; GLYCOLYSIS; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; LIPID STORAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACYL COENZYME A; AGE FACTORS; ANIMALS; BLOOD GLUCOSE; CERAMIDES; DIACYLGLYCEROL O-ACYLTRANSFERASE; DIGLYCERIDES; GENE EXPRESSION; GLUCOSE; GLUCOSE INTOLERANCE; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; ISOENZYMES; LIPIDS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLE FIBERS, FAST-TWITCH; MUSCLE, SKELETAL; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; TRIGLYCERIDES;

EID: 37149002213     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00158.2007     Document Type: Article

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