메뉴 건너뛰기




Volumn 45, Issue 8, 2004, Pages 1475-1481

The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis

Author keywords

Adipose tissue; Free fatty acids; Lipoprotein lipase; Postprandial lipid metabolism; Transgenic mice; Very low density lipoprotein like emulsion

Indexed keywords

ALBUMIN; CARBON 14; CHYLOMICRON; FATTY ACID; LIPOPROTEIN LIPASE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN; VERY LOW DENSITY LIPOPROTEIN RECEPTOR;

EID: 3442880397     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1194/jlr.M400009-JLR200     Document Type: Article
Times cited : (79)

References (29)
  • 2
    • 0026778830 scopus 로고
    • Rabbit very low density lipoprotein receptor: A low density lipoprotein receptor-like protein with distinct ligand specificity
    • Takahashi, S., Y. Kawarabayasi, T. Nakai, J. Sakai, and T. Yamamoto. 1992. Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity. Proc. Natl. Acad. Sci. USA. 89: 9252-9256.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9252-9256
    • Takahashi, S.1    Kawarabayasi, Y.2    Nakai, T.3    Sakai, J.4    Yamamoto, T.5
  • 5
    • 0029077809 scopus 로고
    • Enhancement of the binding of triglyceride-rich lipoproteins to the very low density lipoprotein receptor by apolipoprotein E and lipoprotein lipase
    • Takahashi, S., J. Suzuki, M. Kohno, K. Oida, T. Tamai, S. Miyabo, T. Yamamoto, and T. Nakai. 1995. Enhancement of the binding of triglyceride-rich lipoproteins to the very low density lipoprotein receptor by apolipoprotein E and lipoprotein lipase. J. Biol. Chem. 270: 15747-15754.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15747-15754
    • Takahashi, S.1    Suzuki, J.2    Kohno, M.3    Oida, K.4    Tamai, T.5    Miyabo, S.6    Yamamoto, T.7    Nakai, T.8
  • 7
    • 0035937846 scopus 로고    scopus 로고
    • Transcytosis of lipoprotein lipase across cultured endothelial cells requires both heparan sulfate proteoglycans and the very low density lipoprotein receptor
    • Obunike, J. C., E. P. Lutz, Z. Li, L. Paka, T. Katopodis, D. K. Strickland, K. F. Kozarsky, S. Pillarisetti, and I. J. Goldberg. 2001. Transcytosis of lipoprotein lipase across cultured endothelial cells requires both heparan sulfate proteoglycans and the very low density lipoprotein receptor. J. Biol. Chem. 276: 8934-8941.
    • (2001) J. Biol. Chem. , vol.276 , pp. 8934-8941
    • Obunike, J.C.1    Lutz, E.P.2    Li, Z.3    Paka, L.4    Katopodis, T.5    Strickland, D.K.6    Kozarsky, K.F.7    Pillarisetti, S.8    Goldberg, I.J.9
  • 8
    • 0031181543 scopus 로고    scopus 로고
    • Lipoprotein lipase (EC 3.1.1.34) targeting of lipoproteins to receptors
    • Beisiegel, U., and J. Heeren. 1997. Lipoprotein lipase (EC 3.1.1.34) targeting of lipoproteins to receptors. Proc. Nutr. Soc. 56: 731-737.
    • (1997) Proc. Nutr. Soc. , vol.56 , pp. 731-737
    • Beisiegel, U.1    Heeren, J.2
  • 9
    • 0029115499 scopus 로고
    • Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor
    • Frykman, P. K., M. S. Brown, T. Yamamoto, J. L. Goldstein, and J. Herz. 1995. Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor. Proc. Natl. Acad. Sci. USA. 92: 8453-8457.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8453-8457
    • Frykman, P.K.1    Brown, M.S.2    Yamamoto, T.3    Goldstein, J.L.4    Herz, J.5
  • 11
    • 0034521695 scopus 로고    scopus 로고
    • LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice
    • Tacken, P. J., B. Teusink, M. C. Jong, D. Harats, L. M. Havekes, K. W. van Dijk, and M. H. Hofker. 2000. LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice. J. Lipid Res. 41: 2055-2062.
    • (2000) J. Lipid Res. , vol.41 , pp. 2055-2062
    • Tacken, P.J.1    Teusink, B.2    Jong, M.C.3    Harats, D.4    Havekes, L.M.5    Van Dijk, K.W.6    Hofker, M.H.7
  • 12
    • 0037155899 scopus 로고    scopus 로고
    • Very low density lipoprotein (VLDL) receptor-deficient mice have reduced lipoprotein lipase activity Possible causes of hypertriglyceridemia and reduced body mass with VLDL receptor deficiency
    • Yagyu, H., E. P. Lutz, Y. Kako, S. Marks, Y. Hu, S. Y. Choi, A. Bensadoun, and I. J. Goldberg. 2002. Very low density lipoprotein (VLDL) receptor-deficient mice have reduced lipoprotein lipase activity Possible causes of hypertriglyceridemia and reduced body mass with VLDL receptor deficiency. J. Biol. Chem. 277: 10037-10043.
    • (2002) J. Biol. Chem. , vol.277 , pp. 10037-10043
    • Yagyu, H.1    Lutz, E.P.2    Kako, Y.3    Marks, S.4    Hu, Y.5    Choi, S.Y.6    Bensadoun, A.7    Goldberg, I.J.8
  • 13
    • 0031007874 scopus 로고    scopus 로고
    • The tissue-specific expression of lipoprotein lipase: Implications for energy and lipoprotein metabolism
    • Zechner, R. 1997. The tissue-specific expression of lipoprotein lipase: implications for energy and lipoprotein metabolism. Curr. Opin. Lipidol. 8: 77-88.
    • (1997) Curr. Opin. Lipidol. , vol.8 , pp. 77-88
    • Zechner, R.1
  • 14
    • 0037343188 scopus 로고    scopus 로고
    • Contribution of fatty acids released from lipolysis of plasma triglycerides to total plasma fatty acid flux and tissue-specific fatty acid uptake
    • Teusink, B., P. J. Voshol, V. E. Dahlmans, P. C. Rensen, H. Pijl, J. A. Romijn, and L. M. Havekes. 2003. Contribution of fatty acids released from lipolysis of plasma triglycerides to total plasma fatty acid flux and tissue-specific fatty acid uptake. Diabetes. 52: 614-620.
    • (2003) Diabetes , vol.52 , pp. 614-620
    • Teusink, B.1    Voshol, P.J.2    Dahlmans, V.E.3    Rensen, P.C.4    Pijl, H.5    Romijn, J.A.6    Havekes, L.M.7
  • 15
    • 0027319705 scopus 로고
    • Analysis of techniques to obtain plasma for measurement of levels of free fatty acids
    • Zambon, A., S. I. Hashimoto, and J. D. Brunzell. 1993. Analysis of techniques to obtain plasma for measurement of levels of free fatty acids. J. Lipid Res. 34: 1021-1028.
    • (1993) J. Lipid Res. , vol.34 , pp. 1021-1028
    • Zambon, A.1    Hashimoto, S.I.2    Brunzell, J.D.3
  • 16
    • 0025357576 scopus 로고
    • Rapid and simple isolation procedure for lipoprotein lipase from human milk
    • Zechner, R. 1990. Rapid and simple isolation procedure for lipoprotein lipase from human milk. Biochim. Biophys. Acta. 1044: 20-25.
    • (1990) Biochim. Biophys. Acta , vol.1044 , pp. 20-25
    • Zechner, R.1
  • 17
    • 0031010389 scopus 로고    scopus 로고
    • Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo
    • Rensen, P. C., N. Herijgers, M. H. Netscher, S. C. Meskers, M. van Eck, and T. J. van Berkel. 1997. Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo. J. Lipid Res. 38: 1070-1084.
    • (1997) J. Lipid Res. , vol.38 , pp. 1070-1084
    • Rensen, P.C.1    Herijgers, N.2    Netscher, M.H.3    Meskers, S.C.4    Van Eck, M.5    Van Berkel, T.J.6
  • 18
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh, E. G., and W. J. Dyer. 1959. A rapid method of total lipid extraction and purification. Can. J. Med. Sci. 37: 911-917.
    • (1959) Can. J. Med. Sci. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 19
    • 0027177642 scopus 로고
    • Lipoprotein lipase gene expression: Physiological regulators at the transcriptional and post-transcriptional level
    • Enerback, S., and J. M. Gimble. 1993. Lipoprotein lipase gene expression: physiological regulators at the transcriptional and post-transcriptional level. Biochim. Biophys. Acta. 1169: 107-125.
    • (1993) Biochim. Biophys. Acta , vol.1169 , pp. 107-125
    • Enerback, S.1    Gimble, J.M.2
  • 20
    • 0035292694 scopus 로고    scopus 로고
    • Lipoprotein lipase: Physiology, biochemistry and molecular biology
    • Goldberg, I. J., and M. Merkel. 2001. Lipoprotein lipase: physiology, biochemistry and molecular biology. Front. Biosci. 6: D388-D405.
    • (2001) Front. Biosci. , vol.6
    • Goldberg, I.J.1    Merkel, M.2
  • 21
    • 0030661768 scopus 로고    scopus 로고
    • Dietary regulation of the very low density lipoprotein receptor in mouse heart and fat
    • Kwok, S., A. Singh-Bist, V. Natu, and F. B. Kraemer. 1997. Dietary regulation of the very low density lipoprotein receptor in mouse heart and fat. Horm. Metab. Res. 29: 524-529.
    • (1997) Horm. Metab. Res. , vol.29 , pp. 524-529
    • Kwok, S.1    Singh-Bist, A.2    Natu, V.3    Kraemer, F.B.4
  • 24
    • 0028819754 scopus 로고
    • Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes
    • Weinstock, P. H., C. L. Bisgaier, K. Aalto-Setala, H. Radner, R. Ramakrishnan, S. Levak-Frank, A. D. Essenburg, R. Zechner, and J. L. Breslow. 1995. Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes. J. Clin. Invest. 96: 2555-2568.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2555-2568
    • Weinstock, P.H.1    Bisgaier, C.L.2    Aalto-Setala, K.3    Radner, H.4    Ramakrishnan, R.5    Levak-Frank, S.6    Essenburg, A.D.7    Zechner, R.8    Breslow, J.L.9
  • 25
    • 0027296725 scopus 로고
    • Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia
    • Shimada, M., H. Shimano, T. Gotoda, K. Yamamoto, M. Kawamura, T. Inaba, Y. Yazaki, and N. Yamada. 1993. Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia. J. Biol. Chem. 268: 17924-17929.
    • (1993) J. Biol. Chem. , vol.268 , pp. 17924-17929
    • Shimada, M.1    Shimano, H.2    Gotoda, T.3    Yamamoto, K.4    Kawamura, M.5    Inaba, T.6    Yazaki, Y.7    Yamada, N.8
  • 26
    • 0025030698 scopus 로고
    • Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice
    • Ito, Y., N. Azrolan, A. O'Connell, A. Walsh, and J. L. Breslow. 1990. Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice. Science. 249: 790-793.
    • (1990) Science , vol.249 , pp. 790-793
    • Ito, Y.1    Azrolan, N.2    O'Connell, A.3    Walsh, A.4    Breslow, J.L.5
  • 27
    • 0034749662 scopus 로고    scopus 로고
    • Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice
    • Jong, M. C., P. C. Rensen, V. E. Dahlmans, H. van der Boom, T. J. van Berkel, and L. M. Havekes. 2001. Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice. J. Lipid Res. 42: 1578-1585.
    • (2001) J. Lipid Res. , vol.42 , pp. 1578-1585
    • Jong, M.C.1    Rensen, P.C.2    Dahlmans, V.E.3    Van Der Boom, H.4    Van Berkel, T.J.5    Havekes, L.M.6
  • 28
    • 0029079312 scopus 로고
    • COOH-terminal disruption of lipoprotein lipase in mice is lethal in homozygotes, but heterozygotes have elevated triglycerides and impaired enzyme activity
    • Coleman, T., R. L. Seip, J. M. Gimble, D. Lee, N. Maeda, and C. F. Semenkovich. 1995. COOH-terminal disruption of lipoprotein lipase in mice is lethal in homozygotes, but heterozygotes have elevated triglycerides and impaired enzyme activity. J. Biol. Chem. 270: 12518-12525.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12518-12525
    • Coleman, T.1    Seip, R.L.2    Gimble, J.M.3    Lee, D.4    Maeda, N.5    Semenkovich, C.F.6
  • 29
    • 0033104838 scopus 로고    scopus 로고
    • Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor
    • Jong, M. C., K. W. van Dijk, V. E. Dahlmans, H. van der Boom, K. Kobayashi, K. Oka, G. Siest, L. Chan, M. H. Hofker, and L. M. Havekes. 1999. Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor. Biochem. J. 338: 281-287.
    • (1999) Biochem. J. , vol.338 , pp. 281-287
    • Jong, M.C.1    Van Dijk, K.W.2    Dahlmans, V.E.3    Van Der Boom, H.4    Kobayashi, K.5    Oka, K.6    Siest, G.7    Chan, L.8    Hofker, M.H.9    Havekes, L.M.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.