Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury

Circulation

Volumn 114, Issue 16, 2006, Pages 1721-1728

  Dyck, Jason R B ^a   Hopkins, Teresa A ^a   Bonnet, Sebastien ^a   Michelakis, Evangelos D ^a   Young, Martin E ^b   Watanabe, Miho ^c   Kawase, Yosuke ^c   Jishage, Kou Ichi ^c   Lopaschuk, Gary D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c Chugai Research Institute for Medical Science Inc   (Japan)

Author keywords

Drugs; Fatty acids; Glucose; Ischemia; Malonyl coenzyme A; Metabolism; Reperfusion

Indexed keywords

FATTY ACID; GLUCOSE; MALONYL COENZYME A; MALONYL COENZYME A DECARBOXYLASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENERGY METABOLISM; ENZYME DEFICIENCY; FATTY ACID OXIDATION; FEMALE; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE OXIDATION; GLUCOSE UTILIZATION; GLYCOLYSIS; HEART FUNCTION; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION;

ANIMALS; CARBOXY-LYASES; FEMALE; GENE DELETION; GLUCOSE; HEART; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL ISCHEMIA; OXIDATION-REDUCTION;

EID: 33750211736     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.106.642009     Document Type: Article

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