Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation

Cardiovascular Research

Volumn 89, Issue 1, 2011, Pages 148-156

  Zhang, Liyan ^a   Ussher, John R ^a   Oka, Tatsujiro ^a   Cadete, Virgilio J J ^a   Wagg, Cory ^a   Lopaschuk, Gary D ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Diacylglycerol; Diacylglycerol acyltransferase; High fat diet; Insulin resistance; Protein kinase C

Indexed keywords

CERAMIDE; DIACYLGLYCEROL; DIACYLGLYCEROL ACYLTRANSFERASE; GLUCOSE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; INSULIN; LONG CHAIN FATTY ACID COENZYME A LIGASE; MALONYL COENZYME A DECARBOXYLASE; PROTEIN KINASE C ALPHA; S6 KINASE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE OXIDATION; HEART; HEART MUSCLE; HEART PERFUSION; INSULIN RESISTANCE; INSULIN SENSITIVITY; ISOLATED HEART; LIPID ANALYSIS; LIPID DIET; LIPID STORAGE; LOW FAT DIET; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ACYL COENZYME A; ANIMALS; CARBOXY-LYASES; DIETARY FATS; DIGLYCERIDES; ENERGY METABOLISM; GLUCOSE; HEART; INSULIN; INSULIN RESISTANCE; LIPID METABOLISM; LIPOLYSIS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, CARDIOVASCULAR; MYOCARDIUM; OXIDATION-REDUCTION; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA;

EID: 78650481257     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvq266     Document Type: Article

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