메뉴 건너뛰기




Volumn 296, Issue 6, 2009, Pages

Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis

Author keywords

1 acylglycerol 3 phosphate acyltransferase; Glycerol 3 phosphate acyltransferase; Phosphatidate phosphatase

Indexed keywords

1 ACYLGLYCEROPHOSPHATE ACYLTRANSFERASE; 1 ACYLGLYCEROPHOSPHATE ACYLTRANSFERASE 1; 1 ACYLGLYCEROPHOSPHATE ACYLTRANSFERASE 2; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE 1; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE 2; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE 3; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LIPIN 1; LIPIN 2; LIPIN 3; MESSENGER RNA; PHOSPHATIDATE PHOSPHATASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 66849089697     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.90958.2008     Document Type: Review
Times cited : (341)

References (127)
  • 2
    • 33646145315 scopus 로고    scopus 로고
    • Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: Cloning, tissue distribution, gene structure, and enzymatic activity
    • Agarwal AK, Barnes RI, Garg A. Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: cloning, tissue distribution, gene structure, and enzymatic activity. Arch Biochem Biophys 449: 64-76, 2006.
    • (2006) Arch Biochem Biophys , vol.449 , pp. 64-76
    • Agarwal, A.K.1    Barnes, R.I.2    Garg, A.3
  • 3
    • 0038607416 scopus 로고    scopus 로고
    • Congenital generalized lipodystrophy: Significance of triglyceride biosynthetic pathways
    • DOI 10.1016/S1043-2760(03)00078-X
    • Agarwal AK, Garg A. Congenital generalized lipodystrophy: significance of triglyceride biosynthetic pathways. Trends Endocrinol Metab 14: 214-221, 2003. (Pubitemid 36841479)
    • (2003) Trends in Endocrinology and Metabolism , vol.14 , Issue.5 , pp. 214-221
    • Agarwal, A.K.1    Garg, A.2
  • 4
    • 32944460924 scopus 로고    scopus 로고
    • Genetic basis of lipodystrophies and management of metabolic complications
    • DOI 10.1146/annurev.med.57.022605.114424
    • Agarwal AK, Garg A. Genetic basis of lipodystrophies and management of metabolic complications. Annu Rev Med 57: 297-311, 2006. (Pubitemid 43261993)
    • (2006) Annual Review of Medicine , vol.57 , pp. 297-311
    • Agarwal, A.K.1    Garg, A.2
  • 5
    • 33750310241 scopus 로고    scopus 로고
    • Genetic disorders of adipose tissue development, differentiation, and death
    • DOI 10.1146/annurev.genom.7.080505.115715
    • Agarwal AK, Garg A. Genetic disorders of adipose tissue development, differentiation, and death. Annu Rev Genomics Hum Genet 7: 175-199, 2006. (Pubitemid 44627927)
    • (2006) Annual Review of Genomics and Human Genetics , vol.7 , pp. 175-199
    • Agarwal, A.K.1    Garg, A.2
  • 7
    • 34447104351 scopus 로고    scopus 로고
    • Functional characterization of human 1-acylglycerol-3-phosphate-O- acyltransferase isoform 9: Cloning, tissue distribution, gene structure, and enzymatic activity
    • DOI 10.1677/JOE-07-0027
    • Agarwal AK, Sukumaran S, Bartz R, Barnes RI, Garg A. Functional characterization of human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 9: cloning, tissue distribution, gene structure, and enzymatic activity. J Endocrinol 193: 445-457, 2007. (Pubitemid 47028695)
    • (2007) Journal of Endocrinology , vol.193 , Issue.3 , pp. 445-457
    • Agarwal, A.K.1    Sukumaran, S.2    Bartz, R.3    Barnes, R.I.4    Garg, A.5
  • 8
    • 0032512848 scopus 로고    scopus 로고
    • Characterization of a human lysophosphatidic acid acyltransferase that is encoded by a gene located in the class III region of the human major histocompatibility complex
    • DOI 10.1074/jbc.273.7.4096
    • Aguado B, Campbell RD. Characterization of a human lysophosphatidic acid acyltransferase that is encoded by a gene located in the class III region of the human major histocompatibility complex. J Biol Chem 273: 4096-4105, 1998. (Pubitemid 28103277)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.7 , pp. 4096-4105
    • Aguado, B.1    Campbell, R.D.2
  • 12
    • 0001321864 scopus 로고
    • The enzymatic synthesis of cytidine diphosphate choline
    • Borkenhagen LF, Kennedy EP. The enzymatic synthesis of cytidine diphosphate choline. J Biol Chem 227: 951-962, 1957.
    • (1957) J Biol Chem , vol.227 , pp. 951-962
    • Borkenhagen, L.F.1    Kennedy, E.P.2
  • 13
    • 14844284989 scopus 로고    scopus 로고
    • Lipid phosphate phosphatases and related proteins: Signaling functions in development, cell division, and cancer
    • DOI 10.1002/jcb.20126
    • Brindley DN. Lipid phosphate phosphatases and related proteins: signaling functions in development, cell division, and cancer. J Cell Biochem 92: 900-912, 2004. (Pubitemid 44264240)
    • (2004) Journal of Cellular Biochemistry , vol.92 , Issue.5 , pp. 900-912
    • Brindley, D.N.1
  • 15
    • 66849125040 scopus 로고    scopus 로고
    • Phosphatidate degradation: Phosphatidate phosphatases (lipins) and lipid phosphate phosphatases
    • In press
    • Brindley DN, Pilquil C, Sariahmetoglu M, Reue K. Phosphatidate degradation: Phosphatidate phosphatases (lipins) and lipid phosphate phosphatases. Biochim Biophys Acta. In press.
    • Biochim Biophys Acta
    • Brindley, D.N.1    Pilquil, C.2    Sariahmetoglu, M.3    Reue, K.4
  • 16
    • 38049030169 scopus 로고    scopus 로고
    • Acute effects of insulin on the activity of mitochondrial GPAT1 in primary adipocytes
    • Bronnikov GE, Aboulaich N, Vener AV, Stralfors P. Acute effects of insulin on the activity of mitochondrial GPAT1 in primary adipocytes. Biochem Biophys Res Commun 367: 201-207, 2008.
    • (2008) Biochem Biophys Res Commun , vol.367 , pp. 201-207
    • Bronnikov, G.E.1    Aboulaich, N.2    Vener, A.V.3    Stralfors, P.4
  • 18
    • 3843084029 scopus 로고    scopus 로고
    • A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse
    • DOI 10.1074/jbc.M402930200
    • Cao J, Liu Y, Lockwood J, Burn P, Shi Y. A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse. J Biol Chem 279: 31727-31734, 2004. (Pubitemid 39037844)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.30 , pp. 31727-31734
    • Cao, J.1    Liu, Y.2    Lockwood, J.3    Burn, P.4    Shi, Y.5
  • 19
    • 59149106049 scopus 로고    scopus 로고
    • Phosphatidic acid phosphatase, a key enzyme in the regulation of lipid synthesis
    • Carman GM, Han GS. Phosphatidic acid phosphatase, a key enzyme in the regulation of lipid synthesis. J Biol Chem 284: 2593-2597, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 2593-2597
    • Carman, G.M.1    Han, G.S.2
  • 20
    • 33751216445 scopus 로고    scopus 로고
    • Roles of phosphatidate phosphatase enzymes in lipid metabolism
    • DOI 10.1016/j.tibs.2006.10.003, PII S0968000406002933
    • Carman GM, Han GS. Roles of phosphatidate phosphatase enzymes in lipid metabolism. Trends Biochem Sci 31: 694-699, 2006. (Pubitemid 44791946)
    • (2006) Trends in Biochemical Sciences , vol.31 , Issue.12 , pp. 694-699
    • Carman, G.M.1    Han, G.-S.2
  • 21
    • 33847006599 scopus 로고    scopus 로고
    • The Liver X Receptor (LXR) and hepatic lipogenesis: The carbohydrate-response element-binding protein is a target gene of LXR
    • DOI 10.1074/jbc.M605023200
    • Cha JY, Repa JJ. The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR. J Biol Chem 282: 743-751, 2007. (Pubitemid 47076632)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.1 , pp. 743-751
    • Cha, J.-Y.1    Repa, J.J.2
  • 24
    • 0345171460 scopus 로고    scopus 로고
    • Enzymes of triacylglycerol synthesis and their regulation
    • DOI 10.1016/S0163-7827(03)00051-1
    • Coleman RA, Lee DP. Enzymes of triacylglycerol synthesis and their regulation. Prog Lipid Res 43: 134-176, 2004. (Pubitemid 37492937)
    • (2004) Progress in Lipid Research , vol.43 , Issue.2 , pp. 134-176
    • Coleman, R.A.1    Lee, D.P.2
  • 27
    • 34548421642 scopus 로고    scopus 로고
    • Hepatic lipin 1beta expression is diminished in insulin-resistant obese subjects and is reactivated by marked weight loss
    • DOI 10.2337/db07-0480
    • Croce MA, Eagon JC, LaRiviere LL, Korenblat KM, Klein S, Finck BN. Hepatic lipin-1beta expression is diminished in insulin-resistant obese subjects and is reactivated by marked weight loss. Diabetes 56: 2395-2399, 2007. (Pubitemid 47358247)
    • (2007) Diabetes , vol.56 , Issue.9 , pp. 2395-2399
    • Croce, M.A.1    Eagon, J.C.2    Lariviere, L.L.3    Korenblat, K.M.4    Klein, S.5    Finck, B.N.6
  • 28
    • 33749595083 scopus 로고    scopus 로고
    • Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival
    • DOI 10.1002/cncr.22184
    • Diefenbach CS, Soslow RA, Iasonos A, Linkov I, Hedvat C, Bonham L, Singer J, Barakat RR, Aghajanian C, Dupont J. Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival. Cancer 107: 1511-1519, 2006. (Pubitemid 44546911)
    • (2006) Cancer , vol.107 , Issue.7 , pp. 1511-1519
    • Diefenbach, C.S.M.1    Soslow, R.A.2    Iasonos, A.3    Linkov, I.4    Hedvat, C.5    Bonham, L.6    Singer, J.7    Barakat, R.R.8    Aghajanian, C.9    Dupont, J.10
  • 29
    • 33947542353 scopus 로고    scopus 로고
    • Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns
    • DOI 10.1074/jbc.M610745200
    • Donkor J, Sariahmetoglu M, Dewald J, Brindley DN, Reue K. Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns. J Biol Chem 282: 3450-3457, 2007. (Pubitemid 47084457)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.6 , pp. 3450-3457
    • Donkor, J.1    Sariahmetoglu, M.2    Dewald, J.3    Brindley, D.N.4    Reue, K.5
  • 30
    • 38149072281 scopus 로고    scopus 로고
    • Adipose tissue lipin-1 expression is correlated with peroxisome proliferator-activated receptor alpha gene expression and insulin sensitivity in healthy young men
    • Donkor J, Sparks LM, Xie H, Smith SR, Reue K. Adipose tissue lipin-1 expression is correlated with peroxisome proliferator-activated receptor alpha gene expression and insulin sensitivity in healthy young men. J Clin Endocrinol Metab 93: 233-239, 2008.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 233-239
    • Donkor, J.1    Sparks, L.M.2    Xie, H.3    Smith, S.R.4    Reue, K.5
  • 31
    • 33744822477 scopus 로고    scopus 로고
    • Effect of lysophosphatidic acid acyltransferase-beta inhibition in acute leukemia
    • DOI 10.1016/j.leukres.2005.11.018, PII S0145212605004443
    • Douvas MG, Hogan KN, Ji Y, Hollenback D, Bonham L, Singer JW, Mitchell BS. Effect of lysophosphatidic acid acyltransferase-beta inhibition in acute leukemia. Leuk Res 30: 1027-1036, 2006. (Pubitemid 43831183)
    • (2006) Leukemia Research , vol.30 , Issue.8 , pp. 1027-1036
    • Douvas, M.G.1    Hogan, K.N.2    Ji, Y.3    Hollenback, D.4    Bonham, L.5    Singer, J.W.6    Mitchell, B.S.7
  • 32
    • 0034465086 scopus 로고    scopus 로고
    • CDNA cloning, expression and chromosomal localization of two human lysophosphatidic acid acyltransferases
    • Eberhardt C, Gray PW, Tjoelker LW. cDNA cloning, expression and chromosomal localization of two human lysophosphatidic acid acyltransferases. Adv Exp Med Biol 469: 351-356, 1999.
    • (1999) Adv Exp Med Biol , vol.469 , pp. 351-356
    • Eberhardt, C.1    Gray, P.W.2    Tjoelker, L.W.3
  • 33
    • 0030789284 scopus 로고    scopus 로고
    • Human lysophosphatidic acid acyltransferase: CDNA cloning, expression, and localization to chromosome 9q34.3
    • DOI 10.1074/jbc.272.32.20299
    • Eberhardt C, Gray PW, Tjoelker LW. Human lysophosphatidic acid acyltransferase. cDNA cloning, expression, and localization to chromosome 9q343. J Biol Chem 272: 20299-20305, 1997. (Pubitemid 27340144)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.32 , pp. 20299-20305
    • Eberhardt, C.1    Gray, P.W.2    Tjoelker, L.W.3
  • 36
    • 22244469461 scopus 로고    scopus 로고
    • Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome)
    • DOI 10.1136/jmg.2005.030759
    • Ferguson PJ, Chen S, Tayeh MK, Ochoa L, Leal SM, Pelet A, Munnich A, Lyonnet S, Majeed HA, El-Shanti H. Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome). J Med Genet 42: 551-557, 2005. (Pubitemid 40993830)
    • (2005) Journal of Medical Genetics , vol.42 , Issue.7 , pp. 551-557
    • Ferguson, P.J.1    Chen, S.2    Tayeh, M.K.3    Ochoa, L.4    Leal, S.M.5    Pelet, A.6    Munnich, A.7    Lyonnet, S.8    Majeed, H.A.9    El-Shanti, H.10
  • 39
    • 66849089864 scopus 로고    scopus 로고
    • Thematic review series: Glycerolipids. Mammalian glycerol-3-phosphate acyltransferases: new genes for an old activity
    • Gimeno RE, Cao J. Thematic review series: glycerolipids. Mammalian glycerol-3-phosphate acyltransferases: new genes for an old activity. J Lipid Res 49: 2079-2088, 2008.
    • (2008) J Lipid Res , vol.49 , pp. 2079-2088
    • Gimeno, R.E.1    Cao, J.2
  • 40
    • 31644447235 scopus 로고    scopus 로고
    • Phenotypic heterogeneity in biochemical parameters correlates with mutations in AGPAT2 or Seipin genes among Berardinelli-Seip congenital lipodystrophy patients
    • DOI 10.1007/s10545-005-0038-5
    • Gomes KB, Pardini VC, Ferreira AC, Fernandes AP. Phenotypic heterogeneity in biochemical parameters correlates with mutations in AGPAT2 or Seipin genes among Berardinelli-Seip congenital lipodystrophy patients. J Inherit Metab Dis 28: 1123-1131, 2005. (Pubitemid 43168949)
    • (2005) Journal of Inherited Metabolic Disease , vol.28 , Issue.6 , pp. 1123-1131
    • Gomes, K.B.1    Pardini, V.C.2    De Souza Ferreira, A.C.3    Fernandes, A.P.4
  • 41
    • 0026654779 scopus 로고
    • Effects of sphingosine, albumin and unsaturated fatty acids on the activation and translocation of phosphatidate phosphohydrolases in rat hepatocytes
    • Gomez-Muñoz A, Hamza EH, Brindley DN. Effects of sphingosine, albumin and unsaturated fatty acids on the activation and translocation of phosphatidate phosphohydrolases in rat hepatocytes. Biochim Biophys Acta 1127: 49-56, 1992.
    • (1992) Biochim Biophys Acta , vol.1127 , pp. 49-56
    • Gomez-Muñoz, A.1    Hamza, E.H.2    Brindley, D.N.3
  • 42
    • 34347402636 scopus 로고    scopus 로고
    • Regulation of Triglyceride Metabolism II. Function of mitochondrial GPAT1 in the regulation of triacylglycerol biosynthesis and insulin action
    • DOI 10.1152/ajpgi.00553.2006
    • Gonzalez-Baró MR, Lewin TM, Coleman RA. Regulation of Triglyceride Metabolism II. Function of mitochondrial GPAT1 in the regulation of triacylglycerol biosynthesis and insulin action. Am J Physiol Gastrointest Liver Physiol 292: G1195-G1199, 2007. (Pubitemid 47084642)
    • (2007) American Journal of Physiology - Gastrointestinal and Liver Physiology , vol.292 , Issue.5
    • Gonzalez-Baro, M.R.1    Lewin, T.M.2    Coleman, R.A.3
  • 44
    • 33947726025 scopus 로고    scopus 로고
    • Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice
    • DOI 10.1016/j.yexmp.2006.12.004, PII S0014480006001535
    • Hammond LE, Albright CD, He L, Rusyn I, Watkins SM, Doughman SD, Lemasters JJ, Coleman RA. Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice. Exp Mol Pathol 82: 210-219, 2007. (Pubitemid 46505131)
    • (2007) Experimental and Molecular Pathology , vol.82 , Issue.2 , pp. 210-219
    • Hammond, L.E.1    Albright, C.D.2    He, L.3    Rusyn, I.4    Watkins, S.M.5    Doughman, S.D.6    Lemasters, J.J.7    Coleman, R.A.8
  • 45
    • 0036889152 scopus 로고    scopus 로고
    • Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition
    • DOI 10.1128/MCB.22.23.8204-8214.2002
    • Hammond LE, Gallagher PA, Wang S, Hiller S, Kluckman KD, Posey-Marcos EL, Maeda N, Coleman RA. Mitochondrial glycerol-3-phosphate acyltransferase- deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition. Mol Cell Biol 22: 8204-8214, 2002. (Pubitemid 35304054)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.23 , pp. 8204-8214
    • Hammond, L.E.1    Gallagher, P.A.2    Wang, S.3    Hiller, S.4    Kluckman, K.D.5    Posey-Marcos, E.L.6    Maeda, N.7    Coleman, R.A.8
  • 47
    • 37549018969 scopus 로고    scopus 로고
    • The cellular functions of the yeast lipin homolog PAH1p are dependent on its phosphatidate phosphatase activity
    • Han GS, Siniossoglou S, Carman GM. The cellular functions of the yeast lipin homolog PAH1p are dependent on its phosphatidate phosphatase activity. J Biol Chem 282: 37026-37035, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 37026-37035
    • Han, G.S.1    Siniossoglou, S.2    Carman, G.M.3
  • 48
    • 33646920976 scopus 로고    scopus 로고
    • 2+-dependent phosphatidate phosphatase enzyme
    • DOI 10.1074/jbc.M600425200
    • Han GS, Wu WI, Carman GM. The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme. J Biol Chem 281: 9210-9218, 2006. (Pubitemid 43864636)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.14 , pp. 9210-9218
    • Han, G.-S.1    Wu, W.-I.2    Carman, G.M.3
  • 49
    • 11144253452 scopus 로고    scopus 로고
    • Enzymatic activity of naturally occurring 1-acylglycerol-3-phosphate-O- Acyltransferase 2 mutants associated with congenital generalized lipodystrophy
    • DOI 10.1016/j.bbrc.2004.12.024, PII S0006291X04027925
    • Haque W, Garg A, Agarwal AK. Enzymatic activity of naturally occurring 1-acylglycerol-3-phosphate-O-acyltransferase 2 mutants associated with congenital generalized lipodystrophy. Biochem Biophys Res Commun 327: 446-453, 2005. (Pubitemid 40040496)
    • (2005) Biochemical and Biophysical Research Communications , vol.327 , Issue.2 , pp. 446-453
    • Haque, W.1    Garg, A.2    Agarwal, A.K.3
  • 53
    • 0031941001 scopus 로고    scopus 로고
    • A conserved histidine is essential for glycerolipid acyltransferase catalysis
    • Heath RJ, Rock CO. A conserved histidine is essential for glycerolipid acyltransferase catalysis. J Bacteriol 180: 1425-1430, 1998. (Pubitemid 28125725)
    • (1998) Journal of Bacteriology , vol.180 , Issue.6 , pp. 1425-1430
    • Heath, R.J.1    Rock, C.O.2
  • 54
    • 34548148047 scopus 로고    scopus 로고
    • Thematic review series: Adipocyte Biology - Lipodystrophies: Windows on adipose biology and metabolism
    • DOI 10.1194/jlr.R700004-JLR200
    • Hegele RA, Joy TR, Al-Attar SA, Rutt BK. Thematic review series: Adipocyte Biology. Lipodystrophies: windows on adipose biology and metabolism. J Lipid Res 48: 1433-1444, 2007. (Pubitemid 47312005)
    • (2007) Journal of Lipid Research , vol.48 , Issue.7 , pp. 1433-1444
    • Hegele, R.A.1    Joy, T.R.2    Al-Attar, S.A.3    Rutt, B.K.4
  • 58
    • 66849122202 scopus 로고    scopus 로고
    • Intestinal lipid absorption
    • January 21, doi:10.1152/ajpendo.90899.2008
    • Iqbal J, Hussain M. Intestinal lipid absorption. Am J Physiol Endocrinol Metab (January 21, 2009). doi:10.1152/ajpendo.90899.2008.
    • (2009) Am J Physiol Endocrinol Metab
    • Iqbal, J.1    Hussain, M.2
  • 59
    • 0014935325 scopus 로고
    • The utilization of the alpha-glycerophosphate and monoglyceride pathways for phosphatidyl choline biosynthesis in the intestine
    • Johnston JM, Paultauf F, Schiller CM, Schultz LD. The utilization of the alpha-glycerophosphate and monoglyceride pathways for phosphatidyl choline biosynthesis in the intestine. Biochim Biophys Acta 218: 124-133, 1970.
    • (1970) Biochim Biophys Acta , vol.218 , pp. 124-133
    • Johnston, J.M.1    Paultauf, F.2    Schiller, C.M.3    Schultz, L.D.4
  • 61
    • 0000476676 scopus 로고
    • Biosynthesis of complex lipids
    • Kennedy EP. Biosynthesis of complex lipids. Fed Proc 20: 934-940, 1961.
    • (1961) Fed Proc , vol.20 , pp. 934-940
    • Kennedy, E.P.1
  • 62
    • 0000749205 scopus 로고
    • The function of cytidine coenzymes in the biosynthesis of phospholipids
    • Kennedy EP, Weiss SB. The function of cytidine coenzymes in the biosynthesis of phospholipids. J Biol Chem 222: 193-214, 1956.
    • (1956) J Biol Chem , vol.222 , pp. 193-214
    • Kennedy, E.P.1    Weiss, S.B.2
  • 63
    • 58049218441 scopus 로고    scopus 로고
    • Lipin1 is a key factor for the maturation and maintenance of adipocytes in the regulatory network with CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma 2
    • Koh YK, Lee MY, Kim JW, Kim M, Moon JS, Lee YJ, Ahn YH, Kim KS. Lipin1 is a key factor for the maturation and maintenance of adipocytes in the regulatory network with CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma 2. J Biol Chem 283: 34896-34906, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 34896-34906
    • Koh, Y.K.1    Lee, M.Y.2    Kim, J.W.3    Kim, M.4    Moon, J.S.5    Lee, Y.J.6    Ahn, Y.H.7    Kim, K.S.8
  • 64
    • 0031589572 scopus 로고    scopus 로고
    • CDNA cloning and expression of murine 1-Acyl-sn-glycerol-3-phosphate acyltransferase
    • DOI 10.1006/bbrc.1997.7214
    • Kume K, Shimizu T. cDNA cloning and expression of murine 1-acyl-sn-glycerol-3-phosphate acyltransferase. Biochem Biophys Res Commun 237: 663-666, 1997. (Pubitemid 27434744)
    • (1997) Biochemical and Biophysical Research Communications , vol.237 , Issue.3 , pp. 663-666
    • Kume, K.1    Shimizu, T.2
  • 66
    • 0025951848 scopus 로고
    • Characterization of the peripheral neuropathy in neonatal and adult mice that are homozygous for the fatty liver dystrophy (fld) mutation
    • Langner CA, Birkenmeier EH, Roth KA, Bronson RT, Gordon JI. Characterization of the peripheral neuropathy in neonatal and adult mice that are homozygous for the fatty liver dystrophy (fld) mutation. J Biol Chem 266: 11955-11964, 1991. (Pubitemid 21907042)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.18 , pp. 11955-11964
    • Langner, C.A.1    Birkenmeier, E.H.2    Roth, K.A.3    Bronson, R.T.4    Gordon, J.I.5
  • 67
    • 0024399652 scopus 로고
    • The fatty liver dystrophy (fld) mutation. a new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities
    • Langner CA, Brikenmeier EH, Ben-Zeev O, Schotz MC, Sweet HO, Davisson MT, Gordon JI. The fatty liver dystrophy (fld) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities. J Biol Chem 264: 7994-8003, 1989. (Pubitemid 19137280)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.14 , pp. 7994-8003
    • Langner, C.A.1    Birkenmeier, E.H.2    Ben-Zeev, O.3    Schotz, M.C.4    Sweet, H.O.5    Davisson, M.T.6    Gordon, J.I.7
  • 69
    • 0010044876 scopus 로고    scopus 로고
    • The structure and functions of human lysophosphatidic acid acyltransferases
    • Leung DW. The structure and functions of human lysophosphatidic acid acyltransferases. Front Biosci 6: D944-D953, 2001.
    • (2001) Front Biosci , vol.6
    • Leung, D.W.1
  • 70
    • 1842741311 scopus 로고    scopus 로고
    • Identification of a New Glycerol-3-phosphate Acyltransferase Isoenzyme, mtGPAT2, in Mitochondria
    • DOI 10.1074/jbc.M314032200
    • Lewin TM, Schwerbrock NM, Lee DP, Coleman RA. Identification of a new glycerol-3-phosphate acyltransferase isoenzyme, mtGPAT2, in mitochondria. J Biol Chem 279: 13488-13495, 2004. (Pubitemid 38468873)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.14 , pp. 13488-13495
    • Lewin, T.M.1    Schwerbrock, N.M.J.2    Lee, D.P.3    Coleman, R.A.4
  • 72
    • 0141644278 scopus 로고    scopus 로고
    • Cloning and identification of the human LPAAT-zeta gene, a novel member of the lysophosphatidic acid acyltransferase family
    • DOI 10.1007/s10038-003-0045-z
    • Li D, Yu L, Wu H, Shan Y, Guo J, Dang Y, Wei Y, Zhao S. Cloning and identification of the human LPAAT-zeta gene, a novel member of the lysophosphatidic acid acyltransferase family. J Hum Genet 48: 438-442, 2003. (Pubitemid 37221560)
    • (2003) Journal of Human Genetics , vol.48 , Issue.8 , pp. 438-442
    • Li, D.1    Yu, L.2    Wu, H.3    Shan, Y.4    Guo, J.5    Dang, Y.6    Wei, Y.7    Zhao, S.8
  • 73
    • 33645820583 scopus 로고    scopus 로고
    • Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation
    • DOI 10.1096/fj.05-4568com
    • Lindén D, William-Olsson L, Ahnmark A, Ekroos K, Hallberg C, Sjögren HP, Becker B, Svensson L, Clapham JC, Oscarsson J, Schreyer S. Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation. FASEB J 20: 434-443, 2006. (Pubitemid 44933320)
    • (2006) FASEB Journal , vol.20 , Issue.3 , pp. 434-443
    • Linden, D.1    William-Olsson, L.2    Ahnmark, A.3    Ekroos, K.4    Hallberg, C.5    Sjogren, H.P.6    Becker, B.7    Svensson, L.8    Clapham, J.C.9    Oscarsson, J.10    Schreyer, S.11
  • 74
    • 3042569137 scopus 로고    scopus 로고
    • Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis
    • DOI 10.1194/jlr.M400010-JLR200
    • Lindén D, William-Olsson L, Rhedin M, Asztély AK, Clapham JC, Schreyer S. Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis. J Lipid Res 45: 1279-1288, 2004. (Pubitemid 38802631)
    • (2004) Journal of Lipid Research , vol.45 , Issue.7 , pp. 1279-1288
    • Linden, D.1    William-Olsson, L.2    Rhedin, M.3    Asztely, A.-K.4    Clapham, J.C.5    Schreyer, S.6
  • 75
    • 38049010121 scopus 로고    scopus 로고
    • Association of lipin 1 gene polymorphisms with measures of energy and glucose metabolism
    • Loos RJ, Rankinen T, Pérusse L, Tremblay A, Després JP, Bouchard C. Association of lipin 1 gene polymorphisms with measures of energy and glucose metabolism. Obesity 15: 2723-2732, 2007.
    • (2007) Obesity , vol.15 , pp. 2723-2732
    • Loos, R.J.1    Rankinen, T.2    Pérusse, L.3    Tremblay, A.4    Després, J.P.5    Bouchard, C.6
  • 76
    • 27444431800 scopus 로고    scopus 로고
    • Expression and regulation of 1-acyl-sn-glycerol-3-phosphate acyltransferases in the epidermis
    • DOI 10.1194/jlr.M500258-JLR200
    • Lu B, Jiang YJ, Man MQ, Brown B, Wlias PM, Feingold KR. Expression and regulation of 1-acyl-sn-glycerol- 3-phosphate acyltransferases in the epidermis. J Lipid Res 46: 2448-2457, 2005. (Pubitemid 41532533)
    • (2005) Journal of Lipid Research , vol.46 , Issue.11 , pp. 2448-2457
    • Lu, B.1    Jiang, Y.J.2    Man, M.Q.3    Brown, B.4    Elias, P.M.5    Feingold, K.R.6
  • 77
    • 12844249385 scopus 로고    scopus 로고
    • Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARalpha in murine heart
    • DOI 10.1042/BJ20041348
    • Lu B, Jiang YJ, Zhou Y, Xu FY, Hatch GM, Choy PC. Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARalpha in murine heart. Biochem J 385: 469-477, 2005. (Pubitemid 40165080)
    • (2005) Biochemical Journal , vol.385 , Issue.2 , pp. 469-477
    • Lu, B.1    Jiang, Y.J.2    Zhou, Y.3    Xu, F.Y.4    Hatch, G.M.5    Choy, P.C.6
  • 82
    • 44949176737 scopus 로고    scopus 로고
    • Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice
    • Nagle CA, Vergnes L, Dejong H, Wang S, Lewin TM, Reue K, Coleman RA. Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice. J Lipid Res 49: 823-831, 2008.
    • (2008) J Lipid Res , vol.49 , pp. 823-831
    • Nagle, C.A.1    Vergnes, L.2    Dejong, H.3    Wang, S.4    Lewin, T.M.5    Reue, K.6    Coleman, R.A.7
  • 83
    • 33745976120 scopus 로고    scopus 로고
    • Cloning and characterization of mouse lung-type acyl-CoA: Lysophosphatidylcholine acyltransferase 1 (LPCAt1): Expression in alveolar type II cells and possible involvement in surfactant production
    • DOI 10.1074/jbc.M600225200
    • Nakanishi H, Shindou H, Hishikawa D, Harayama T, Ogasawara R, Suwabe A, Taguchi R, Shimizu T. Cloning and characterization of mouse lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1). Expression in alveolar type II cells and possible involvement in surfactant production. J Biol Chem 281: 20140-20147, 2006. (Pubitemid 44065788)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.29 , pp. 20140-20147
    • Nakanishi, H.1    Shindou, H.2    Hishikawa, D.3    Harayama, T.4    Ogasawara, R.5    Suwabe, A.6    Taguchi, R.7    Shimizu, T.8
  • 85
    • 19944422401 scopus 로고    scopus 로고
    • Expression of lysophosphatidic acid acyltransferase beta (LPAAT-beta) in ovarian carcinoma: Correlation with tumour grading and prognosis
    • DOI 10.1038/sj.bjc.6602528
    • Niesporek S, Denkert C, Weichert W, Köbel M, Noske A, Sehouli J, Singer JW, Dietel M, Hauptmann S. Expression of lysophosphatidic acid acyltransferase beta (LPAAT-beta) in ovarian carcinoma: correlation with tumour grading and prognosis. Br J Cancer 92: 1729-1736, 2005. (Pubitemid 40756485)
    • (2005) British Journal of Cancer , vol.92 , Issue.9 , pp. 1729-1736
    • Niesporek, S.1    Denkert, C.2    Weichert, W.3    Kobel, M.4    Noske, A.5    Sehouli, J.6    Singer, J.W.7    Dietel, M.8    Hauptmann, S.9
  • 86
    • 33646561211 scopus 로고    scopus 로고
    • Genome-wide expression analysis reveals 100 adrenal gland-dependent circadian genes in the mouse liver
    • Oishi K, Amagai N, Shirai H, Kadota K, Ohkura N, Ishida N. Genome-wide expression analysis reveals 100 adrenal gland-dependent circadian genes in the mouse liver. DNA Res 12: 191-202, 2005.
    • (2005) DNA Res , vol.12 , pp. 191-202
    • Oishi, K.1    Amagai, N.2    Shirai, H.3    Kadota, K.4    Ohkura, N.5    Ishida, N.6
  • 89
    • 27644444065 scopus 로고    scopus 로고
    • Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas
    • DOI 10.1158/1078-0432.CCR-04-2352
    • Pagel JM, Laugen C, Bonham L, Hackman RC, Hockenbery DM, Bhatt R, Hollenback D, Carew H, Singer JW, Press OW. Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas. Clin Cancer Res 11: 4857-4866, 2005. (Pubitemid 41557206)
    • (2005) Clinical Cancer Research , vol.11 , Issue.13 , pp. 4857-4866
    • Pagel, J.M.1    Laugen, C.2    Bonham, L.3    Hackman, R.C.4    Hockenbery, D.M.5    Bhatt, R.6    Hollenback, D.7    Carew, H.8    Singer, J.W.9    Press, O.W.10
  • 91
    • 33744915255 scopus 로고    scopus 로고
    • The C-terminal region of mitochondrial glycerol-3-phosphate acyltransferase-1 interacts with the active site region and is required for activity
    • DOI 10.1016/j.abb.2006.03.009, PII S0003986106001007
    • Pellon-Maison M, Coleman RA, Gonzalez-Baró MR. The C-terminal region of mitochondrial glycerol-3-phosphate acyltransferase-1 interacts with the active site region and is required for activity. Arch Biochem Biophys 450: 157-166, 2006. (Pubitemid 43849622)
    • (2006) Archives of Biochemistry and Biophysics , vol.450 , Issue.2 , pp. 157-166
    • Pellon-Maison, M.1    Coleman, R.A.2    Gonzalez-Baro, M.R.3
  • 92
    • 25444465996 scopus 로고    scopus 로고
    • Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis
    • DOI 10.1074/jbc.M503885200
    • Peterfy M, Phan J, Reue K. Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis. J Biol Chem 280: 32883-32889, 2005. (Pubitemid 41368337)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.38 , pp. 32883-32889
    • Peterfy, M.1    Phan, J.2    Reue, K.3
  • 93
    • 0035163850 scopus 로고    scopus 로고
    • Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin
    • DOI 10.1038/83685
    • Peterfy M, Phan J, Xu P, Reue K. Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin. Nat Genet 27: 121-124, 2001. (Pubitemid 32044532)
    • (2001) Nature Genetics , vol.27 , Issue.1 , pp. 121-124
    • Peterfy, M.1    Phan, J.2    Xu, P.3    Reue, K.4
  • 94
    • 3142685480 scopus 로고    scopus 로고
    • Lipin expression preceding peroxisome proliferator-activated receptor-gamma is critical for adipogenesis in vivo and in vitro
    • DOI 10.1074/jbc.M403506200
    • Phan J, Peterfy M, Reue K. Lipin expression preceding peroxisome proliferator-activated receptor-gamma is critical for adipogenesis in vivo and in vitro. J Biol Chem 279: 29558-29564, 2004. (Pubitemid 38915837)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.28 , pp. 29558-29564
    • Phan, J.1    Peterfy, M.2    Reue, K.3
  • 95
    • 15944375261 scopus 로고    scopus 로고
    • Lipin, a lipodystrophy and obesity gene
    • DOI 10.1016/j.cmet.2004.12.002, PII S1550413104000087
    • Phan J, Reue K. Lipin, a lipodystrophy and obesity gene. Cell Metab 1: 73-83, 2005. (Pubitemid 43960586)
    • (2005) Cell Metabolism , vol.1 , Issue.1 , pp. 73-83
    • Phan, J.1    Reue, K.2
  • 96
    • 59649088176 scopus 로고    scopus 로고
    • Thematic Review Series: Glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism
    • Reue K, Brindley DN. Thematic Review Series: Glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism. J Lipid Res 49: 2493-2503, 2008.
    • (2008) J Lipid Res , vol.49 , pp. 2493-2503
    • Reue, K.1    Brindley, D.N.2
  • 97
    • 84863494132 scopus 로고    scopus 로고
    • Lipin proteins and metabolic homeostasis
    • In press
    • Reue K, Dwyer JR. Lipin proteins and metabolic homeostasis. J Lipid Res. In press.
    • J Lipid Res
    • Reue, K.1    Dwyer, J.R.2
  • 98
    • 0033942169 scopus 로고    scopus 로고
    • Adipose tissue deficiency, glucose intolerance, and increased atherosclerosis result from mutation in the mouse fatty liver dystrophy (fld) gene
    • Reue K, Xu P, Wang XP, Slavin BG. Adipose tissue deficiency, glucose intolerance, and increased atherosclerosis result from mutation in the mouse fatty liver dystrophy (fld) gene. J Lipid Res 41: 1067-1076, 2000. (Pubitemid 30483010)
    • (2000) Journal of Lipid Research , vol.41 , Issue.7 , pp. 1067-1076
    • Reue, K.1    Xu, P.2    Wang, X.-P.3    Slavin, B.G.4
  • 99
    • 37449000957 scopus 로고    scopus 로고
    • The lipin protein family: Dual roles in lipid biosynthesis and gene expression
    • Reue K, Zhang P. The lipin protein family: dual roles in lipid biosynthesis and gene expression. FEBS Lett 582: 90-96, 2008.
    • (2008) FEBS Lett , vol.582 , pp. 90-96
    • Reue, K.1    Zhang, P.2
  • 100
    • 0035145685 scopus 로고    scopus 로고
    • Overexpression of 1-acyl-glycerol-3-phosphate acyltransferase-alpha enhances lipid storage in cellular models of adipose tissue and skeletal muscle
    • Ruan H, Pownall HJ. Overexpression of 1-acyl-glycerol-3-phosphate acyltransferase-alpha enhances lipid storage in cellular models of adipose tissue and skeletal muscle. Diabetes 50: 233-240, 2001. (Pubitemid 32127277)
    • (2001) Diabetes , vol.50 , Issue.2 , pp. 233-240
    • Ruan, H.1    Pownall, H.J.2
  • 101
    • 67650096808 scopus 로고    scopus 로고
    • Beyond Triglyceride Synthesis: The Dynamic Functional Roles of MGAT and DGAT Enzymes in Energy Metabolism
    • December 30, doi:10.1152/ajpendo.90949.2008
    • Shi Y, Cheng D. Beyond Triglyceride Synthesis: The Dynamic Functional Roles of MGAT and DGAT Enzymes in Energy Metabolism. Am J Physiol Endocrinol Metab (December 30, 2008). doi:10.1152/ajpendo.90949.2008.
    • (2008) Am J Physiol Endocrinol Metab
    • Shi, Y.1    Cheng, D.2
  • 103
    • 0344442411 scopus 로고    scopus 로고
    • Phenotypic Heterogeneity in Body Fat Distribution in Patients with Congenital Generalized Lipodystrophy Caused by Mutations in the AGPAT2 or Seipin Genes
    • DOI 10.1210/jc.2003-030835
    • Simha V, Garg A. Phenotypic heterogeneity in body fat distribution in patients with congenital generalized lipodystrophy caused by mutations in the AGPAT2 or seipin genes. J Clin Endocrinol Metab 88: 5433-5437, 2003. (Pubitemid 37452750)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.11 , pp. 5433-5437
    • Simha, V.1    Garg, A.2
  • 104
    • 38349133922 scopus 로고    scopus 로고
    • Mammalian acyl-CoA:lysophosphatidylcholine acyltransferase enzymes
    • Soupene E, Fyrst H, Kuypers FA. Mammalian acyl-CoA: lysophosphatidylcholine acyltransferase enzymes. Proc Natl Acad Sci USA 105: 88-93, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 88-93
    • Soupene, E.1    Fyrst, H.2    Kuypers, F.A.3
  • 106
    • 0030850425 scopus 로고    scopus 로고
    • A human cDNA sequence with homology to non-mammalian lysophosphatidic acid acyltransferases
    • Stamps AC, Elmore MA, Hill ME, Kelly K, Makda AA, Finnen MJ. A human cDNA sequence with homology to non-mammalian lysophosphatidic acid acyltransferases. Biochem J 326: 455-461, 1997. (Pubitemid 27417223)
    • (1997) Biochemical Journal , vol.326 , Issue.2 , pp. 455-461
    • Stamps, A.C.1    Elmore, M.A.2    Hill, M.E.3    Kelly, K.4    Makda, A.A.5    Finnen, M.J.6
  • 107
    • 67649421649 scopus 로고    scopus 로고
    • Functional characterization of the human 1-acylglycerol-3-phosphate-O- acyltransferase isoform 10 / glycerol-3-phosphate acyltransferase isoform 3 (AGPAT10/GPAT3)
    • In press
    • Sukumaran S, Barnes R, Garg A, Agarwal A. Functional characterization of the human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 10 / glycerol-3-phosphate acyltransferase isoform 3 (AGPAT10/GPAT3). J Mol Endocrinol. In press.
    • J Mol Endocrinol
    • Sukumaran, S.1    Barnes, R.2    Garg, A.3    Agarwal, A.4
  • 110
    • 34147158237 scopus 로고    scopus 로고
    • Regulation of Triglyceride Metabolism. I. Eukaryotic neutral lipid synthesis: "Many ways to skin ACAT or a DGAT"
    • Turkish A, Sturley SL. Regulation of Triglyceride Metabolism. I. Eukaryotic neutral lipid synthesis: "Many ways to skin ACAT or a DGAT". Am J Physiol Gastrointest Liver Physiol 292: G953-G957, 2007.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Turkish, A.1    Sturley, S.L.2
  • 112
    • 33845980542 scopus 로고    scopus 로고
    • A role of lipin in human obesity and insulin resistance: Relation to adipocyte glucose transport and GLUT4 expression
    • DOI 10.1194/jlr.M600272-JLR200
    • van Harmelen V, Rydén M, Sjölin E, Hoffstedt J. A role of lipin in human obesity and insulin resistance: relation to adipocyte glucose transport and GLUT4 expression. J Lipid Res 48: 201-206, 2007. (Pubitemid 46052912)
    • (2007) Journal of Lipid Research , vol.48 , Issue.1 , pp. 201-206
    • Van Harmelen, V.1    Ryden, M.2    Sjolin, E.3    Hoffstedt, J.4
  • 113
    • 0028104966 scopus 로고
    • Purification and characterization of glycerophosphate acyltransferase from rat liver mitochondria
    • Vancura A, Haldar D. Purification and characterization of glycerophosphate acyltransferase from rat liver mitochondria. J Biol Chem 27209-27215, 1994. (Pubitemid 24346536)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.44 , pp. 27209-27215
    • Vancura, A.1    Haldar, D.2
  • 115
    • 34247626853 scopus 로고    scopus 로고
    • The Small Molecule Harmine Is an Antidiabetic Cell-Type-Specific Regulator of PPARgamma Expression
    • DOI 10.1016/j.cmet.2007.03.010, PII S1550413107000733
    • Waki H, Park KW, Mitro N, Pei L, Damoiseaux R, Wilpitz DC, Reue K, Saez E, Tontonoz P. The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression. Cell Metab 5: 357-370, 2007. (Pubitemid 46667757)
    • (2007) Cell Metabolism , vol.5 , Issue.5 , pp. 357-370
    • Waki, H.1    Park, K.W.2    Mitro, N.3    Pei, L.4    Damoiseaux, R.5    Wilpitz, D.C.6    Reue, K.7    Saez, E.8    Tontonoz, P.9
  • 117
    • 0030925549 scopus 로고    scopus 로고
    • Cloning and expression of two human lysophosphatidic acid acyltransferase cDNAs that enhance cytokine-induced signaling responses in cells
    • West J, Tompkins CK, Balantac N, Nudelman E, Meengs B, White T, Bursten S, Coleman J, Kumar A, Singer JW, Leung DW. Cloning and expression of two human lysophosphatidic acid acyltransferase cDNAs that enhance cytokine-induced signaling responses in cells. DNA Cell Biol 16: 691-701, 1997. (Pubitemid 27276833)
    • (1997) DNA and Cell Biology , vol.16 , Issue.6 , pp. 691-701
    • West, J.1
  • 120
    • 33845537627 scopus 로고    scopus 로고
    • Lipin deficiency impairs diurnal metabolic fuel switching
    • DOI 10.2337/db06-0260
    • Xu J, Lee WN, Phan J, Saad MF, Reue K, Kurland IJ. Lipin deficiency impairs diurnal metabolic fuel switching. Diabetes 55: 3429-3438, 2006. (Pubitemid 44923602)
    • (2006) Diabetes , vol.55 , Issue.12 , pp. 3429-3438
    • Xu, J.1    Lee, W.N.P.2    Phan, J.3    Saad, M.F.4    Reue, K.5    Kurland, I.J.6
  • 121
    • 0035920102 scopus 로고    scopus 로고
    • ATP-independent fatty acyl-coenzyme a synthesis from phospholipid: Coenzyme A-dependent transacylation activity toward lysophosphatidic acid catalyzed by acyl-coenzyme A:lysophosphatidic acid acyltransferase
    • DOI 10.1074/jbc.M101795200
    • Yamashita A, Kawagishi N, Miyashita T, Nagatsuka T, Sugiura T, Kume K, Shimizu T, Waku K. ATP-independent fatty acyl-coenzyme A synthesis from phospholipid: coenzyme A-dependent transacylation activity toward lysophosphatidic acid catalyzed by acyl-coenzyme A: lysophosphatidic acid acyltransferase. J Biol Chem 276: 26745-26752, 2001. (Pubitemid 37410571)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.29 , pp. 26745-26752
    • Yamashita, A.1    Kawagishi, N.2    Miyashita, T.3    Nagatsuka, T.4    Sugiura, T.5    Kume, K.6    Shimizu, T.7    Waku, K.8
  • 123
    • 33750872010 scopus 로고    scopus 로고
    • Lipin expression is attenuated in adipose tissue of insulin-resistant human subjects and increases with peroxisome proliferator-activated receptor gamma activation
    • DOI 10.2337/db05-1688
    • Yao-Borengasser A, Rasouli N, Varma V, Miles LM, Phanavanh B, Starks TN, Phan J, Spencer HJ 3rd, McGehee RE Jr, Reue K, Kern PA. Lipin expression is attenuated in adipose tissue of insulin-resistant human subjects and increases with peroxisome proliferator-activated receptor gamma activation. Diabetes 55: 2811-2818, 2006. (Pubitemid 44923681)
    • (2006) Diabetes , vol.55 , Issue.10 , pp. 2811-2818
    • Yao-Borengasser, A.1    Rasouli, N.2    Varma, V.3    Miles, L.M.4    Phanavanh, B.5    Starks, T.N.6    Phan, J.7    Spencer III, H.J.8    McGehee Jr., R.E.9    Reue, K.10    Kern, P.A.11
  • 125
    • 58149457426 scopus 로고    scopus 로고
    • Thematic review series: Glycerolipids. DGAT enzymes and triacylglycerol biosynthesis
    • Yen CL, Stone SJ, Koliwad S, Harris C, Farese RV Jr. Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis. J Lipid Res 49: 2283-2301, 2008.
    • (2008) J Lipid Res , vol.49 , pp. 2283-2301
    • Yen, C.L.1    Stone, S.J.2    Koliwad, S.3    Harris, C.4    Farese Jr., R.V.5
  • 127
    • 50949098238 scopus 로고    scopus 로고
    • Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis
    • Zhang P, O'Loughlin L, Brindley DN, Reue K. Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis. J Lipid Res 49: 1519-1528, 2008.
    • (2008) J Lipid Res , vol.49 , pp. 1519-1528
    • Zhang, P.1    O'Loughlin, L.2    Brindley, D.N.3    Reue, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.