-
1
-
-
64649096897
-
Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity
-
Ahmadian M, et al. 2009. Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity. Diabetes 58:855-866.
-
(2009)
Diabetes
, vol.58
, pp. 855-866
-
-
Ahmadian, M.1
-
2
-
-
77955176286
-
Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha
-
Banke NH, et al. 2010. Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha. Circ. Res. 107:233-241.
-
(2010)
Circ. Res.
, vol.107
, pp. 233-241
-
-
Banke, N.H.1
-
3
-
-
0033933236
-
Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth
-
Barger PM, Brandt JM, Leone TC, Weinheimer CJ, Kelly DP. 2000. Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth. J. Clin. Invest. 105:1723-1730.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1723-1730
-
-
Barger, P.M.1
Brandt, J.M.2
Leone, T.C.3
Weinheimer, C.J.4
Kelly, D.P.5
-
4
-
-
78049425280
-
High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila
-
Birse RT, et al. 2010. High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila. Cell Metab. 12:533-544.
-
(2010)
Cell Metab
, vol.12
, pp. 533-544
-
-
Birse, R.T.1
-
6
-
-
3442892340
-
Phosphatidylcholine deficiency upregulates enzymes of triacylglycerol metabolism in CHO cells
-
Caviglia JM, De Gomez Dumm IN, Coleman RA, Igal RA. 2004. Phosphatidylcholine deficiency upregulates enzymes of triacylglycerol metabolism in CHO cells. J. Lipid Res. 45:1500-1509.
-
(2004)
J. Lipid Res.
, vol.45
, pp. 1500-1509
-
-
Caviglia, J.M.1
De Gomez Dumm, I.N.2
Coleman, R.A.3
Igal, R.A.4
-
7
-
-
0035061419
-
A novel mouse model of lipotoxic cardiomyopathy
-
Chiu HC, et al. 2001. A novel mouse model of lipotoxic cardiomyopathy. J. Clin. Invest. 107:813-822.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 813-822
-
-
Chiu, H.C.1
-
8
-
-
0042315364
-
Cardiac lipid accumulation associated with diastolic dysfunction in obese mice
-
Christoffersen C, et al. 2003. Cardiac lipid accumulation associated with diastolic dysfunction in obese mice. Endocrinology 144:3483-3490.
-
(2003)
Endocrinology
, vol.144
, pp. 3483-3490
-
-
Christoffersen, C.1
-
9
-
-
70449158340
-
A simple method for the isolation and purification of total lipides from animal tissues
-
Folch J, Lees M, Sloane Stanley GH. 1957. A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 226:497-509.
-
(1957)
J. Biol. Chem.
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloane Stanley, G.H.3
-
10
-
-
70350002081
-
The development of a metabolic disease phenotype in CTP, phosphoethanolamine cytidylyltransferase-deficient mice
-
Fullerton MD, Hakimuddin F, Bonen A, Bakovic M. 2009. The development of a metabolic disease phenotype in CTP:phosphoethanolamine cytidylyltransferase-deficient mice. J. Biol. Chem. 284:25704-25713.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 25704-25713
-
-
Fullerton, M.D.1
Hakimuddin, F.2
Bonen, A.3
Bakovic, M.4
-
11
-
-
36849071229
-
Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake
-
Gao S, et al. 2007. Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake. Proc. Natl. Acad. Sci. U. S. A. 104:17358-17363.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 17358-17363
-
-
Gao, S.1
-
12
-
-
79551498811
-
A murine model of isolated cardiac steatosis leads to cardiomyopathy
-
Glenn DJ, et al. 2011. A murine model of isolated cardiac steatosis leads to cardiomyopathy. Hypertension 57:216-222.
-
(2011)
Hypertension
, vol.57
, pp. 216-222
-
-
Glenn, D.J.1
-
13
-
-
0025822785
-
Isolation and characterization of the mouse cardiac myosin heavy chain genes
-
Gulick J, Subramaniam A, Neumann J, Robbins J. 1991. Isolation and characterization of the mouse cardiac myosin heavy chain genes. J. Biol. Chem. 266:9180-9185.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 9180-9185
-
-
Gulick, J.1
Subramaniam, A.2
Neumann, J.3
Robbins, J.4
-
14
-
-
78549277139
-
Loss of PI3Kgamma enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress
-
Guo D, et al. 2010. Loss of PI3Kgamma enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress. Circ. Res. 107:1275-1289.
-
(2010)
Circ. Res.
, vol.107
, pp. 1275-1289
-
-
Guo, D.1
-
15
-
-
33646462136
-
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
-
Haemmerle G, et al. 2006. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 312:734-737.
-
(2006)
Science
, vol.312
, pp. 734-737
-
-
Haemmerle, G.1
-
16
-
-
80052454265
-
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1
-
Haemmerle G, et al. 2011. ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1. Nat. Med. 17: 1076-1085.
-
(2011)
Nat. Med.
, vol.17
, pp. 1076-1085
-
-
Haemmerle, G.1
-
17
-
-
33750495997
-
Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart
-
Heather LC, et al. 2006. Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart. Cardiovasc. Res. 72:430-437.
-
(2006)
Cardiovasc. Res.
, vol.72
, pp. 430-437
-
-
Heather, L.C.1
-
18
-
-
57149097132
-
Triglyceride deposit cardiomyovasculopathy
-
Hirano K, Ikeda Y, Zaima N, Sakata Y, Matsumiya G. 2008. Triglyceride deposit cardiomyovasculopathy. N. Engl. J. Med. 359:2396-2398.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 2396-2398
-
-
Hirano, K.1
Ikeda, Y.2
Zaima, N.3
Sakata, Y.4
Matsumiya, G.5
-
19
-
-
34250793866
-
Overexpression of the Na+/H+ exchanger and ischemia-reperfusion injury in the myocardium
-
Imahashi K, Mraiche F, Steenbergen C, Murphy E, Fliegel L. 2007. Overexpression of the Na+/H+ exchanger and ischemia-reperfusion injury in the myocardium. Am. J. Physiol. Heart Circ. Physiol. 292:H2237-H2247.
-
(2007)
Am. J. Physiol. Heart Circ. Physiol.
, vol.292
-
-
Imahashi, K.1
Mraiche, F.2
Steenbergen, C.3
Murphy, E.4
Fliegel, L.5
-
20
-
-
79953297052
-
Contraction-induced skeletal muscle FAT/CD36 trafficking and FA uptake isAMPKindependent
-
Jeppesen J, et al. 2011. Contraction-induced skeletal muscle FAT/CD36 trafficking and FA uptake isAMPKindependent. J. Lipid Res. 52:699-711.
-
(2011)
J. Lipid Res.
, vol.52
, pp. 699-711
-
-
Jeppesen, J.1
-
21
-
-
24044458235
-
Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice
-
Kassiri Z, et al. 2005. Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice. Circ. Res. 97:380-390.
-
(2005)
Circ. Res.
, vol.97
, pp. 380-390
-
-
Kassiri, Z.1
-
23
-
-
1842538563
-
Fatty acid translocase/CD36 deficiency does not energetically or functionally compromise hearts before or after ischemia
-
Kuang M, Febbraio M, Wagg C, Lopaschuk GD, Dyck JR. 2004. Fatty acid translocase/CD36 deficiency does not energetically or functionally compromise hearts before or after ischemia. Circulation 109:1550-1557.
-
(2004)
Circulation
, vol.109
, pp. 1550-1557
-
-
Kuang, M.1
Febbraio, M.2
Wagg, C.3
Lopaschuk, G.D.4
Dyck, J.R.5
-
24
-
-
4544252278
-
Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice
-
Lee Y, et al. 2004. Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 101: 13624-13629.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 13624-13629
-
-
Lee, Y.1
-
25
-
-
70350442568
-
Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis
-
Leonardi R, Frank MW, Jackson PD, Rock CO, Jackowski S. 2009. Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis. J. Biol. Chem. 284:27077-27089.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 27077-27089
-
-
Leonardi, R.1
Frank, M.W.2
Jackson, P.D.3
Rock, C.O.4
Jackowski, S.5
-
27
-
-
78651490662
-
Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila
-
Lim HY, Wang W, Wessells RJ, Ocorr K, Bodmer R. 2011. Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila. Genes Dev. 25:189-200.
-
(2011)
Genes Dev
, vol.25
, pp. 189-200
-
-
Lim, H.Y.1
Wang, W.2
Wessells, R.J.3
Ocorr, K.4
Bodmer, R.5
-
28
-
-
73649094432
-
DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity
-
Liu L, et al. 2009. DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity. J. Biol. Chem. 284:36312-36323.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 36312-36323
-
-
Liu, L.1
-
29
-
-
74949133862
-
Myocardial fatty acid metabolism in health and disease
-
Lopaschuk GD, Ussher JR, Folmes CD, Jaswal JS, Stanley WC. 2010. Myocardial fatty acid metabolism in health and disease. Physiol. Rev. 90: 207-258.
-
(2010)
Physiol. Rev.
, vol.90
, pp. 207-258
-
-
Lopaschuk, G.D.1
Ussher, J.R.2
Folmes, C.D.3
Jaswal, J.S.4
Stanley, W.C.5
-
31
-
-
70350349875
-
Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome
-
Marfella R, et al. 2009. Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome. J. Lipid Res. 50: 2314-2323.
-
(2009)
J. Lipid Res.
, vol.50
, pp. 2314-2323
-
-
Marfella, R.1
-
32
-
-
33645825813
-
Adiposity of the heart, revisited
-
McGavock JM, Victor RG, Unger RH, Szczepaniak LS. 2006. Adiposity of the heart, revisited. Ann. Intern. Med. 144:517-524.
-
(2006)
Ann. Intern. Med.
, vol.144
, pp. 517-524
-
-
McGavock, J.M.1
Victor, R.G.2
Unger, R.H.3
Szczepaniak, L.S.4
-
33
-
-
78650683294
-
Myocardial steatosis and biventricular strain and strain rate imaging in patients with type 2 diabetes mellitus
-
Ng AC, et al. 2010. Myocardial steatosis and biventricular strain and strain rate imaging in patients with type 2 diabetes mellitus. Circulation 122:2538-2544.
-
(2010)
Circulation
, vol.122
, pp. 2538-2544
-
-
Ng, A.C.1
-
34
-
-
39149097521
-
The absence of endogenous lipid oxidation in early stage heart failure exposes limits in lipid storage and turnover
-
O'Donnell JM, Fields AD, Sorokina N, Lewandowski ED. 2008. The absence of endogenous lipid oxidation in early stage heart failure exposes limits in lipid storage and turnover. J. Mol. Cell. Cardiol. 44:315-322.
-
(2008)
J. Mol. Cell. Cardiol.
, vol.44
, pp. 315-322
-
-
O'Donnell, J.M.1
Fields, A.D.2
Sorokina, N.3
Lewandowski, E.D.4
-
35
-
-
78751496304
-
Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning
-
Ong KT, Mashek MT, Bu SY, Greenberg AS, Mashek DG. 2011. Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning. Hepatology 53:116-126.
-
(2011)
Hepatology
, vol.53
, pp. 116-126
-
-
Ong, K.T.1
Mashek, M.T.2
Bu, S.Y.3
Greenberg, A.S.4
Mashek, D.G.5
-
36
-
-
44449171291
-
Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress
-
Oudit GY, et al. 2008. Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress. Cardiovasc. Res. 78:505-514.
-
(2008)
Cardiovasc. Res.
, vol.78
, pp. 505-514
-
-
Oudit, G.Y.1
-
37
-
-
0022970190
-
Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells
-
Preiss J, et al. 1986. Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells. J. Biol. Chem. 261:8597-8600.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 8597-8600
-
-
Preiss, J.1
-
38
-
-
45149123679
-
Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis
-
Reid BN, et al. 2008. Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis. J. Biol. Chem. 283:13087-13099.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13087-13099
-
-
Reid, B.N.1
-
39
-
-
0025821485
-
Myocardial triglyceride turnover and contribution to energy substrate utilization in isolated working rat hearts
-
Saddik M, Lopaschuk GD. 1991. Myocardial triglyceride turnover and contribution to energy substrate utilization in isolated working rat hearts. J. Biol. Chem. 266:8162-8170.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 8162-8170
-
-
Saddik, M.1
Lopaschuk, G.D.2
-
40
-
-
68049092870
-
Neutral lipid storage disease, genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5
-
Schweiger M, Lass A, Zimmermann R, Eichmann TO, Zechner R. 2009. Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5. Am. J. Physiol. Endocrinol. Metab. 297:E289-E296.
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
-
-
Schweiger, M.1
Lass, A.2
Zimmermann, R.3
Eichmann, T.O.4
Zechner, R.5
-
41
-
-
0032480230
-
Is the cytoprotective effect of trimetazidine associated with lipid metabolism?
-
Sentex E, Sergiel JP, Lucien A, and Grynberg A. 1998. Is the cytoprotective effect of trimetazidine associated with lipid metabolism? Am. J. Cardiol. 82:18K-24K.
-
(1998)
Am. J. Cardiol.
, vol.82
-
-
Sentex, E.1
Sergiel, J.P.2
Lucien, A.3
Grynberg, A.4
-
42
-
-
77957846150
-
PPARgamma-induced cardiolipotoxicity in mice is ameliorated by PPARalpha deficiency despite increases in fatty acid oxidation
-
Son NH, et al. 2010. PPARgamma-induced cardiolipotoxicity in mice is ameliorated by PPARalpha deficiency despite increases in fatty acid oxidation. J. Clin. Invest. 120:3443-3454.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 3443-3454
-
-
Son, N.H.1
-
43
-
-
0037373342
-
Prevention of heart failure in rats by trimetazidine treatment, a consequence of accelerated phospholipid turnover?
-
Tabbi-Anneni I, et al. 2003. Prevention of heart failure in rats by trimetazidine treatment: a consequence of accelerated phospholipid turnover? J. Pharmacol. Exp. Ther. 304:1003-1009.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.304
, pp. 1003-1009
-
-
Tabbi-Anneni, I.1
-
44
-
-
58149311507
-
Phospholipid-mediated signaling and heart disease
-
Tappia PS, Singal T. 2008. Phospholipid-mediated signaling and heart disease. Subcell. Biochem. 49:299-324.
-
(2008)
Subcell. Biochem.
, vol.49
, pp. 299-324
-
-
Tappia, P.S.1
Singal, T.2
-
45
-
-
77449151433
-
Direct regulation of myocardial triglyceride metabolism by the cardiomyocyte circadian clock
-
Tsai JY, et al. 2010. Direct regulation of myocardial triglyceride metabolism by the cardiomyocyte circadian clock. J. Biol. Chem. 285:2918-2929.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 2918-2929
-
-
Tsai, J.Y.1
-
46
-
-
79953787445
-
Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice
-
Turpin SM, et al. 2011. Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice. Diabetologia 54:146-156.
-
(2011)
Diabetologia
, vol.54
, pp. 146-156
-
-
Turpin, S.M.1
-
47
-
-
68049136011
-
Insulin-stimulated cardiac glucose oxidation is increased in high-fat-diet-induced obese mice lacking malonyl CoA decarboxylase
-
Ussher JR, et al. 2009. Insulin-stimulated cardiac glucose oxidation is increased in high-fat-diet-induced obese mice lacking malonyl CoA decarboxylase. Diabetes 58:1766-1775.
-
(2009)
Diabetes
, vol.58
, pp. 1766-1775
-
-
Ussher, J.R.1
-
48
-
-
8844226709
-
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase
-
Zimmermann R, et al. 2004. Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science 306:1383-1386.
-
(2004)
Science
, vol.306
, pp. 1383-1386
-
-
Zimmermann, R.1
|