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Volumn 46, Issue 1, 1997, Pages 3-10

Role of fatty acids in the pathogenesis of insulin resistance and NIDDM

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID BLOOD LEVEL; FATTY ACID METABOLISM; GLUCOSE TRANSPORT; HUMAN; INSULIN RESISTANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

EID: 0031014830     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.46.1.3     Document Type: Review
Times cited : (1483)

References (74)
  • 1
    • 0024341392 scopus 로고
    • Impaired glucose tolerance in the US population
    • Harris MI: Impaired glucose tolerance in the US population. Diabetes Care 12:464-474, 1989
    • (1989) Diabetes Care , vol.12 , pp. 464-474
    • Harris, M.I.1
  • 2
    • 0024223817 scopus 로고
    • The prospective cardiovascular Munster (PROCAM) study: Prevalence of hyperlipidemia in persons with hypertension and/or diabetes mellitus and relationship to coronary heart disease
    • Assmann G, Schulte H: The prospective cardiovascular Munster (PROCAM) study: prevalence of hyperlipidemia in persons with hypertension and/or diabetes mellitus and relationship to coronary heart disease. Am Heart J 116:1713-1724, 1988
    • (1988) Am Heart J , vol.116 , pp. 1713-1724
    • Assmann, G.1    Schulte, H.2
  • 3
    • 0026468362 scopus 로고
    • What if Minkowski had been ageusic? An alternative angle on diabetes
    • McGarry JD: What if Minkowski had been ageusic? An alternative angle on diabetes. Science 258:766-774, 1992
    • (1992) Science , vol.258 , pp. 766-774
    • McGarry, J.D.1
  • 7
    • 0000025241 scopus 로고
    • Influence of the World War II food shortage on the incidence of diabetes mellitus in Japan
    • Goto Y, Nakayama Y, Yagi T: Influence of the World War II food shortage on the incidence of diabetes mellitus in Japan. Diabetes 7:133-135, 1958
    • (1958) Diabetes , vol.7 , pp. 133-135
    • Goto, Y.1    Nakayama, Y.2    Yagi, T.3
  • 8
    • 0001435623 scopus 로고
    • Mangelernahrung und Diabetes Morbiditat
    • Schliack V: Mangelernahrung und Diabetes Morbiditat. Z Klin Med 151:382-396, 1954
    • (1954) Z Klin Med , vol.151 , pp. 382-396
    • Schliack, V.1
  • 9
    • 0025093498 scopus 로고
    • Inducement by fat feeding of basal hyperglycemia in rats with abnormal β-cell function: Model for study of etiology and pathogenesis of NIDDM
    • Pascoe WS, Storlien LH: Inducement by fat feeding of basal hyperglycemia in rats with abnormal β-cell function: model for study of etiology and pathogenesis of NIDDM. Diabetes 39:226-233, 1990
    • (1990) Diabetes , vol.39 , pp. 226-233
    • Pascoe, W.S.1    Storlien, L.H.2
  • 10
    • 0000847623 scopus 로고
    • Non-esterified fatty acids in blood of obese and lean subjects
    • Gorden ES: Non-esterified fatty acids in blood of obese and lean subjects. Am J Clin Nutr 8:740-747, 1960
    • (1960) Am J Clin Nutr , vol.8 , pp. 740-747
    • Gorden, E.S.1
  • 11
    • 0024244339 scopus 로고
    • Measurement of plasma glucose, free fatty acid, lactate and insulin for 24 h in patients with NIDDM
    • Reaven GM, Hollenbeck C, Jeng C-Y, Wu MS, Chen Y-D: Measurement of plasma glucose, free fatty acid, lactate and insulin for 24 h in patients with NIDDM. Diabetes 37:1020-1024, 1988
    • (1988) Diabetes , vol.37 , pp. 1020-1024
    • Reaven, G.M.1    Hollenbeck, C.2    Jeng, C.-Y.3    Wu, M.S.4    Chen, Y.-D.5
  • 13
    • 0024602053 scopus 로고
    • Influence of body fat distribution on free fatty acid metabolism in obesity
    • Jensen MD, Haymond MW, Rizza RA, Cryer PE, Miles JM: Influence of body fat distribution on free fatty acid metabolism in obesity. J Clin Invest 83:1168-1173, 1989
    • (1989) J Clin Invest , vol.83 , pp. 1168-1173
    • Jensen, M.D.1    Haymond, M.W.2    Rizza, R.A.3    Cryer, P.E.4    Miles, J.M.5
  • 14
    • 50549202600 scopus 로고
    • The glucose fatty-acid cycle: Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle PJ, Garland PB, Hales CN, Newsholme EA: The glucose fatty-acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet i:785-789, 1963
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 15
    • 0014322668 scopus 로고
    • Effects of fatty acids on carbohydrate and fatty acid metabolism of rat diaphragm
    • Schonfeld G, Kipnis DM: Effects of fatty acids on carbohydrate and fatty acid metabolism of rat diaphragm. Am J Physiol 215:513-522, 1968
    • (1968) Am J Physiol , vol.215 , pp. 513-522
    • Schonfeld, G.1    Kipnis, D.M.2
  • 16
    • 0014578059 scopus 로고
    • Effect of octanoate on carbohydrate metabolism in red and white muscle of the rhesus monkey
    • Cassens RG, Bocek RM, Beatty CH: Effect of octanoate on carbohydrate metabolism in red and white muscle of the rhesus monkey. Am J Physiol 217:715-719, 1969
    • (1969) Am J Physiol , vol.217 , pp. 715-719
    • Cassens, R.G.1    Bocek, R.M.2    Beatty, C.H.3
  • 17
    • 0015081907 scopus 로고
    • Interrelation of carbohydrate and palmitate metabolism in skeletal muscle
    • Beatty CH, Bocek RM: Interrelation of carbohydrate and palmitate metabolism in skeletal muscle. Am J Physiol 220:1928-1934, 1971
    • (1971) Am J Physiol , vol.220 , pp. 1928-1934
    • Beatty, C.H.1    Bocek, R.M.2
  • 18
    • 0016290713 scopus 로고
    • Glucose metabolism in rat skeletal muscle at rest: Effect of starvation, diabetes, ketone bodies, and free fatty acids
    • Goodman MN, Berger NM, Ruderman NB: Glucose metabolism in rat skeletal muscle at rest: effect of starvation, diabetes, ketone bodies, and free fatty acids. Diabetes 23:881-888, 1974
    • (1974) Diabetes , vol.23 , pp. 881-888
    • Goodman, M.N.1    Berger, N.M.2    Ruderman, N.B.3
  • 25
    • 0023706040 scopus 로고
    • Artificial induction of intravascular lipolysis by lipid-heparin infusions leads to insulin resistance in man
    • Lee HU, Lee HK, Koh CS, Min HK: Artificial induction of intravascular lipolysis by lipid-heparin infusions leads to insulin resistance in man. Diabetologia 31:285-290, 1988
    • (1988) Diabetologia , vol.31 , pp. 285-290
    • Lee, H.U.1    Lee, H.K.2    Koh, C.S.3    Min, H.K.4
  • 27
    • 0028342686 scopus 로고
    • Mechanisms of fatty acid-induced inhibition of glucose uptake
    • Boden G, Chen X, Ruiz J, White JV, Rossetti L: Mechanisms of fatty acid-induced inhibition of glucose uptake. J Clin Invest 93:2438-2446, 1994
    • (1994) J Clin Invest , vol.93 , pp. 2438-2446
    • Boden, G.1    Chen, X.2    Ruiz, J.3    White, J.V.4    Rossetti, L.5
  • 28
    • 0029084869 scopus 로고
    • Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes
    • Boden G, Chen X: Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes. J Clin Invest 96:1261-1268, 1995
    • (1995) J Clin Invest , vol.96 , pp. 1261-1268
    • Boden, G.1    Chen, X.2
  • 29
    • 0025872319 scopus 로고
    • Demonstration of a novel feedback mechanism between FFA oxidation from intracellular and intravascular sources
    • Yki-Jarvinen H, Puhakainen HI, Saloranta C, Groop L, Taskinen M-R: Demonstration of a novel feedback mechanism between FFA oxidation from intracellular and intravascular sources. Am J Physiol 260:E680-E689, 1991
    • (1991) Am J Physiol , vol.260
    • Yki-Jarvinen, H.1    Puhakainen, H.I.2    Saloranta, C.3    Groop, L.4    Taskinen, M.-R.5
  • 30
    • 0025764186 scopus 로고
    • Modulation of hepatic glucose production by non-esterified fatty acids in type 2 (non-insulin-dependent) diabetes mellitus
    • Saloranta C, Franssila-Kallunki A, Ekstrand A, Taskinen M-R, Groop L: Modulation of hepatic glucose production by non-esterified fatty acids in type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 34:409-415, 1991
    • (1991) Diabetologia , vol.34 , pp. 409-415
    • Saloranta, C.1    Franssila-Kallunki, A.2    Ekstrand, A.3    Taskinen, M.-R.4    Groop, L.5
  • 31
    • 0029113227 scopus 로고
    • Interstitial fluid concentrations of glycerol, glucose, and amino acids in human quadricep muscle and adipose tissue: Evidence for significant lipolysis in skeletal muscle
    • Maggs DG, Jacob R, Rife F, Lange R, Leone P, During MJ, Tamborlane WV, Sherwin RS: Interstitial fluid concentrations of glycerol, glucose, and amino acids in human quadricep muscle and adipose tissue: evidence for significant lipolysis in skeletal muscle. J Clin Invest 96:370-377, 1995
    • (1995) J Clin Invest , vol.96 , pp. 370-377
    • Maggs, D.G.1    Jacob, R.2    Rife, F.3    Lange, R.4    Leone, P.5    During, M.J.6    Tamborlane, W.V.7    Sherwin, R.S.8
  • 34
    • 0027136671 scopus 로고
    • Effects of oleate and fatty acids from omental adipocytes on insulin uptake in rat liver cells
    • Kolaczynski JW, Boden G: Effects of oleate and fatty acids from omental adipocytes on insulin uptake in rat liver cells. Endocrinology 133:2871-2874, 1993
    • (1993) Endocrinology , vol.133 , pp. 2871-2874
    • Kolaczynski, J.W.1    Boden, G.2
  • 35
    • 0029151863 scopus 로고
    • Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: Genetic and clinical implications
    • Unger RH: Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: genetic and clinical implications. Diabetes 44:863-870, 1995
    • (1995) Diabetes , vol.44 , pp. 863-870
    • Unger, R.H.1
  • 36
    • 84941021274 scopus 로고
    • Effects of fat infusions on glucose tolerance and insulin plasma levels
    • Felber JP, Vanotti A: Effects of fat infusions on glucose tolerance and insulin plasma levels. Med Exp 10:153-156, 1964
    • (1964) Med Exp , vol.10 , pp. 153-156
    • Felber, J.P.1    Vanotti, A.2
  • 37
    • 0014251318 scopus 로고
    • Effect of acute elevation of plasma glycerol, triglyceride and FFA levels on glucose utilization and plasma insulin
    • Pelkonen R, Miettinen A, Taskinen M-R, Nikkila EA: Effect of acute elevation of plasma glycerol, triglyceride and FFA levels on glucose utilization and plasma insulin. Diabetes 17:76-82, 1968
    • (1968) Diabetes , vol.17 , pp. 76-82
    • Pelkonen, R.1    Miettinen, A.2    Taskinen, M.-R.3    Nikkila, E.A.4
  • 38
    • 0014333141 scopus 로고
    • Stimulation of insulin secretion by noncarbohydrate metabolites
    • Malaisse WJ, Malaisse-Lagae F: Stimulation of insulin secretion by noncarbohydrate metabolites. J Lab Clin Med 72:438-448, 1968
    • (1968) J Lab Clin Med , vol.72 , pp. 438-448
    • Malaisse, W.J.1    Malaisse-Lagae, F.2
  • 39
    • 0015882267 scopus 로고
    • Stimulation of insulin secretion by long-chain free fatty acids
    • Crespin SR, Greenough WB, Steinberg D: Stimulation of insulin secretion by long-chain free fatty acids. J Clin Invest 52:1979-1984, 1973
    • (1973) J Clin Invest , vol.52 , pp. 1979-1984
    • Crespin, S.R.1    Greenough, W.B.2    Steinberg, D.3
  • 40
    • 0016230591 scopus 로고
    • Action of β-hydroxybutyrate, acetoacetate and palmitate on the insulin release from the perfused isolated rat pancreas
    • Goberna RJ, Tamarit J Jr, Fussganger R, Tamarit J, Pfeiffer EF: Action of β-hydroxybutyrate, acetoacetate and palmitate on the insulin release from the perfused isolated rat pancreas. Horm Metab Res 6:256-260, 1974
    • (1974) Horm Metab Res , vol.6 , pp. 256-260
    • Goberna, R.J.1    Tamarit Jr., J.2    Fussganger, R.3    Tamarit, J.4    Pfeiffer, E.F.5
  • 41
    • 0024995157 scopus 로고
    • A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and βcell oxidation through a process likely coupled to fatty acid oxidation
    • Sako Y, Grill VE: A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and βcell oxidation through a process likely coupled to fatty acid oxidation. Endocrinol 127:1580-1589, 1990
    • (1990) Endocrinol , vol.127 , pp. 1580-1589
    • Sako, Y.1    Grill, V.E.2
  • 42
    • 0028268936 scopus 로고
    • Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
    • Zhou Y-P, Grill VE: Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J Clin Invest 93:870-876, 1994
    • (1994) J Clin Invest , vol.93 , pp. 870-876
    • Zhou, Y.-P.1    Grill, V.E.2
  • 43
    • 0029046673 scopus 로고
    • Effects of a 48-h fat infusion on insulin secretion and glucose utilization
    • Boden G, Chen X, Rosner J, Barton M: Effects of a 48-h fat infusion on insulin secretion and glucose utilization. Diabetes 44:1239-1242, 1995
    • (1995) Diabetes , vol.44 , pp. 1239-1242
    • Boden, G.1    Chen, X.2    Rosner, J.3    Barton, M.4
  • 44
    • 0028068288 scopus 로고
    • Mechanism of action of nonglucose insulin secretagogues
    • Liang Y, Matschinsky F: Mechanism of action of nonglucose insulin secretagogues. Ann Rev Nutr 14:59-81, 1994
    • (1994) Ann Rev Nutr , vol.14 , pp. 59-81
    • Liang, Y.1    Matschinsky, F.2
  • 45
  • 46
    • 0013923479 scopus 로고
    • Mechanism for the stimulation of gluconeogenesis by fatty acids in perfused rat liver
    • Williamsson JR, Kreisberg RA, Felts PW: Mechanism for the stimulation of gluconeogenesis by fatty acids in perfused rat liver. Proc Natl Acad Sci USA 6:247-254, 1966
    • (1966) Proc Natl Acad Sci USA , vol.6 , pp. 247-254
    • Williamsson, J.R.1    Kreisberg, R.A.2    Felts, P.W.3
  • 48
    • 0027314195 scopus 로고
    • Fatty acids are potent modulators of lactate utilization in isolated hepatocytes from fed rats
    • Morand C, Remesy C, Demigne C: Fatty acids are potent modulators of lactate utilization in isolated hepatocytes from fed rats. Am J Physiol 264:E816-E823, 1993
    • (1993) Am J Physiol , vol.264
    • Morand, C.1    Remesy, C.2    Demigne, C.3
  • 49
    • 0016711740 scopus 로고
    • Regulation of hepatic gluconeogenesis in the guinea pig by fatty acids and ammonia
    • Jomain-Baum M, Hanson RW: Regulation of hepatic gluconeogenesis in the guinea pig by fatty acids and ammonia. J Biol Chem 250:8978-8985, 1975
    • (1975) J Biol Chem , vol.250 , pp. 8978-8985
    • Jomain-Baum, M.1    Hanson, R.W.2
  • 50
    • 0014670584 scopus 로고
    • Control mechanisms of gluconeogenesis and ketogenesis
    • Williamson J, Browning E, Scholz R: Control mechanisms of gluconeogenesis and ketogenesis. J Biol Chem 224:4607-4616, 1969
    • (1969) J Biol Chem , vol.224 , pp. 4607-4616
    • Williamson, J.1    Browning, E.2    Scholz, R.3
  • 51
    • 0028825129 scopus 로고
    • Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin
    • Rebrin K, Steil GM, Getty L, Bergman RN: Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin. Diabetes 44:1038-1045, 1995
    • (1995) Diabetes , vol.44 , pp. 1038-1045
    • Rebrin, K.1    Steil, G.M.2    Getty, L.3    Bergman, R.N.4
  • 52
    • 0026644792 scopus 로고
    • Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects
    • Fulcher GR, Walker M, Catalano C, Aquis L, Alberti KGMM: Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects. Diabetes 41:1400-1408, 1992
    • (1992) Diabetes , vol.41 , pp. 1400-1408
    • Fulcher, G.R.1    Walker, M.2    Catalano, C.3    Aquis, L.4    Alberti, K.G.M.M.5
  • 53
    • 0028203880 scopus 로고
    • Pronounced blood glucose-lowering effect of the antilipolytic drug acipimox in noninsulin-dependent diabetes mellitus patients during a 3-day intensified treatment period
    • Worm D, Henriksen JE, Vaag A, Thye-Ronn P, Melander A, Beck-Nielsen H: Pronounced blood glucose-lowering effect of the antilipolytic drug acipimox in noninsulin-dependent diabetes mellitus patients during a 3-day intensified treatment period. J Clin Endocrinol Metab 78:717-721, 1994
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 717-721
    • Worm, D.1    Henriksen, J.E.2    Vaag, A.3    Thye-Ronn, P.4    Melander, A.5    Beck-Nielsen, H.6
  • 54
    • 0025949378 scopus 로고
    • Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with noninsulin-dependent diabetes mellitus
    • Vaag A, Skott P, Damsbo P, Gall M-A, Richter EA, Beck-Nielsen H: Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with noninsulin-dependent diabetes mellitus. J Clin Invest 88:1282-1290, 1991
    • (1991) J Clin Invest , vol.88 , pp. 1282-1290
    • Vaag, A.1    Skott, P.2    Damsbo, P.3    Gall, M.-A.4    Richter, E.A.5    Beck-Nielsen, H.6
  • 56
    • 0027515569 scopus 로고
    • Inhibition of lipolysis decreases lipid oxidation and gluconeogenesis from lactate but not fasting hyperglycemia or total hepatic glucose production in NIDDM
    • Puhakainen I, Yki-Jarvinen H: Inhibition of lipolysis decreases lipid oxidation and gluconeogenesis from lactate but not fasting hyperglycemia or total hepatic glucose production in NIDDM. Diabetes 42:1694-1699, 1993
    • (1993) Diabetes , vol.42 , pp. 1694-1699
    • Puhakainen, I.1    Yki-Jarvinen, H.2
  • 57
    • 0021032715 scopus 로고
    • Effect of fatty acids on glucose production and utilization in man
    • Ferrannini E, Barrett E, Bevilacqua S, DeFronzo R: Effect of fatty acids on glucose production and utilization in man. J Clin Invest 72:1737-1747, 1983
    • (1983) J Clin Invest , vol.72 , pp. 1737-1747
    • Ferrannini, E.1    Barrett, E.2    Bevilacqua, S.3    Defronzo, R.4
  • 59
    • 0025775034 scopus 로고
    • Effects of lipid on basal carbohydrate metabolism in normal men
    • Boden G, Jadali F: Effects of lipid on basal carbohydrate metabolism in normal men. Diabetes 40:686-692, 1991
    • (1991) Diabetes , vol.40 , pp. 686-692
    • Boden, G.1    Jadali, F.2
  • 60
    • 0027218865 scopus 로고
    • Interaction between glucose and free fatty acid metabolism in human skeletal muscle
    • Kelley DE, Mokan M, Simoneau J-A, Mandarino LJ: Interaction between glucose and free fatty acid metabolism in human skeletal muscle. J Clin Invest 92:91-98, 1993
    • (1993) J Clin Invest , vol.92 , pp. 91-98
    • Kelley, D.E.1    Mokan, M.2    Simoneau, J.-A.3    Mandarino, L.J.4
  • 62
    • 0025855139 scopus 로고
    • Discovery of a metabolic pathway mediating glucose-induced desensitization of glucose transport system: Role of hexosamine biosynthesis in the induction of insulin resistance
    • Marshall S, Bacote V, Traxinger RR: Discovery of a metabolic pathway mediating glucose-induced desensitization of glucose transport system: role of hexosamine biosynthesis in the induction of insulin resistance. J Biol Chem 266:4706-4712, 1991
    • (1991) J Biol Chem , vol.266 , pp. 4706-4712
    • Marshall, S.1    Bacote, V.2    Traxinger, R.R.3
  • 63
    • 0024379725 scopus 로고
    • Recovery of maximal insulin responsiveness and insulin sensitivity after induction of insulin resistance in primary cultured adipocytes
    • Traxinger RR, Marshall S: Recovery of maximal insulin responsiveness and insulin sensitivity after induction of insulin resistance in primary cultured adipocytes. J Biol Chem 264:8156-8163, 1989
    • (1989) J Biol Chem , vol.264 , pp. 8156-8163
    • Traxinger, R.R.1    Marshall, S.2
  • 64
    • 0027275367 scopus 로고
    • Pre-exposure to glucosamine induces insulin resistance of glucose transport and glycogen synthesis in isolated rat skeletal muscles: Study of mechanisms in muscle and in rat-1 fibroblasts overexpressing the human insulin receptor
    • Robinson KA, Sens DA, Buse MG: Pre-exposure to glucosamine induces insulin resistance of glucose transport and glycogen synthesis in isolated rat skeletal muscles: study of mechanisms in muscle and in rat-1 fibroblasts overexpressing the human insulin receptor. Diabetes 42:1333-1346, 1993
    • (1993) Diabetes , vol.42 , pp. 1333-1346
    • Robinson, K.A.1    Sens, D.A.2    Buse, M.G.3
  • 66
    • 0019413818 scopus 로고
    • Effect of membrane lipid environment on the properties of insulin receptors
    • Ginsberg BH, Brown TJ, Simon I, Spector AA: Effect of membrane lipid environment on the properties of insulin receptors. Diabetes 30:773-780, 1981
    • (1981) Diabetes , vol.30 , pp. 773-780
    • Ginsberg, B.H.1    Brown, T.J.2    Simon, I.3    Spector, A.A.4
  • 67
    • 0019800745 scopus 로고
    • Maintenance of 3T3-L1 cells in cultured media containing saturated fatty acids decreases insulin binding and insulin action
    • Grunfeld C, Baird KL, Kahn CR: Maintenance of 3T3-L1 cells in cultured media containing saturated fatty acids decreases insulin binding and insulin action. Biochem Biophys Res Commun 103:219-226, 1981
    • (1981) Biochem Biophys Res Commun , vol.103 , pp. 219-226
    • Grunfeld, C.1    Baird, K.L.2    Kahn, C.R.3
  • 68
    • 0023615780 scopus 로고
    • Insulin-membrane interactions and membrane fluidity changes
    • Farias RN: Insulin-membrane interactions and membrane fluidity changes. Biochem Biophys Acta 906:459-468, 1987
    • (1987) Biochem Biophys Acta , vol.906 , pp. 459-468
    • Farias, R.N.1
  • 69
    • 0027395358 scopus 로고
    • The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids
    • Borkman M, Storlien LH, Pan DA, Jenkins AB, Chisholm DJ, Campbell LV: The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. N Engl J Med 328:238-244, 1993
    • (1993) N Engl J Med , vol.328 , pp. 238-244
    • Borkman, M.1    Storlien, L.H.2    Pan, D.A.3    Jenkins, A.B.4    Chisholm, D.J.5    Campbell, L.V.6
  • 70
    • 0028587742 scopus 로고
    • Tumor necrosis factor α: A key component of the obesity-diabetes link
    • Hotamisligil GS, Spiegelman BM: Tumor necrosis factor α: a key component of the obesity-diabetes link. Diabetes 43:1271-1278, 1994
    • (1994) Diabetes , vol.43 , pp. 1271-1278
    • Hotamisligil, G.S.1    Spiegelman, B.M.2
  • 71
    • 0342618563 scopus 로고    scopus 로고
    • TNF-α and insulin sensitivity in humans: Effects in vivo of antibody blockade in obese NIDDM patients and in vitro upon human cultured myotubes
    • Hurel S, Ofei F, Wells AN, Newkirk J, Sopwith M, Turnbull D, Taylor R: TNF-α and insulin sensitivity in humans: effects in vivo of antibody blockade in obese NIDDM patients and in vitro upon human cultured myotubes. Exp Clin Endocrinol Diabetes 104 (Suppl. 2):59-60, 1996
    • (1996) Exp Clin Endocrinol Diabetes , vol.104 , Issue.2 SUPPL. , pp. 59-60
    • Hurel, S.1    Ofei, F.2    Wells, A.N.3    Newkirk, J.4    Sopwith, M.5    Turnbull, D.6    Taylor, R.7
  • 72
    • 0028031569 scopus 로고
    • Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes: Central role of tumor necrosis factor-α
    • Hotamisligil GS, Budavari A, Murray D, Spiegelman BM: Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes: central role of tumor necrosis factor-α. J Clin Invest 94:1543-1549, 1994
    • (1994) J Clin Invest , vol.94 , pp. 1543-1549
    • Hotamisligil, G.S.1    Budavari, A.2    Murray, D.3    Spiegelman, B.M.4
  • 74
    • 0029880428 scopus 로고    scopus 로고
    • Effects of prolonged glucose infusion on insulin secretion, clearance, and action in normal subjects
    • Boden G, Ruiz J, Kim C-J, Chen X: Effects of prolonged glucose infusion on insulin secretion, clearance, and action in normal subjects. Am J Physiol 270:E251-E258, 1996
    • (1996) Am J Physiol , vol.270
    • Boden, G.1    Ruiz, J.2    Kim, C.-J.3    Chen, X.4


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